Superfamily : 56954 [ Outer membrane efflux proteins (OEP) ]
Class : Membrane and cell surface proteins and peptides
Fold : Outer membrane efflux proteins (OEP)
# of Members : 5
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1ek9a-  (   1 )                                             enLqVYqqA
d1yc9a-  (  63 )                                wPsanWWqrYqdaqLnhLIeeA
d3pika-  (   1 )    cslapdyqrpampVpqqFs--------lyqNagwrtFFvdnqVktlIseA
d5azpa-  (   1 )    ctvgpdyrtpdtaaAkidaTaskpYdrsrfeslWWkqFddptLnqLVeqS
d5azsa-  (   1 )    csmaptyerpaapvadsWs------------ldwksFIvdaeLrrLVdmA
                                                            aaaaaaaaaa

                             60        70        80        90        100 
d1ek9a-  (  11 )    rlsNpelrksaadrdaafekinearspllpqlglgadytysngyr-----
d1yc9a-  (  85 )    lqhSpslcmamarlkgaqgfarqagairsfdlglaasateskvseryqsa
d3pika-  (  54 )    lvnNrdlrmatlkvqearaqyrltdadrypqlngegsgswsgnl------
d5azpa-  (  51 )    lsgNrdlrvafarLraaralrddvAndrfpvvtsrasadigkgqqpg--v
d5azsa-  (  52 )    LdnnrsLrqtlldieaaraqyriqradrvpglnaaatgnrqrqpad-lsa
                    aaa aaaaaaaaaaaaaaaaaaaaa     bbbbbbbbbbbb        

                             110       120       130       140       150 
d1ek9a-  (  56 )    ----danginsnatsaslqlt-qSi--fdskwraltlqekaAgiqdVtyq
d1yc9a-  ( 135 )    tppd----gwndyGtltlnfq-ydfdfwgkNraavvaAtSelaAaeaesv
d3pika-  (  98 )    kgnt----attrefstglnas-fdldffGrlkNmSeaerQnylateeaqr
d5azpa-  (  99 )    tedr----vnserydlgldsa-weldlfGrIrRqlessdAlseAaeAdlq
d5azsa-  ( 101 )    gnrs----evassyqvglalpeyeldlfGrVkSlTdaalqqylAseeaar
                             bbbbbbbbbbbb bb     aaaaaaaaaaaaaaaaaaaaa

                             160       170       180       190       200 
d1ek9a-  ( 100 )    tdqqtLIlnTAtaYFnVLnaidvLsyTqaqkeaIyrqLdqTtqrfnvglv
d1yc9a-  ( 180 )    aarlmISTsIAnaYAeLarlyaNqetVhaalqvRnktvelLekryangle
d3pika-  ( 143 )    avhilLvSnVAqsYFnQQlAyaQlqiAeetlrnYqqsyafVekqlltgss
d5azpa-  ( 144 )    qlqVsLIAeLVdaYGqLRGAqlrekiAlsNlenQkesrqlTeqlrdagvg
d5azsa-  ( 147 )    aariaLVAeVSqaYLsYDGAlrrlalTrqtlvsReysfalidqrraagaA
                    aaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa    

                             210       220       230       240       250 
d1ek9a-  ( 150 )    aitdvqnAraqydtVlaneltarnnLdnaveqLrqiTg-------nyype
d1yc9a-  ( 230 )    tlgsVsqAkavaasveaellgiqesIqlqknaLAalVgqgpdrAasIeeP
d3pika-  ( 193 )    nvlAleqArgviesTrsdiakrqgelaqAnnaLqllLgs-y---gklpqa
d5azpa-  ( 194 )    aeldVlrAdarlaaTaasvpqLqaeAerarhrIAtLLgqrpeeltvdLsp
d5azsa-  ( 197 )    taldyqealgLVeqAraeqerNlrqkqqafnaLvllLgs-ddAaqAIprs
                     aaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa             

                             260       270       280       290       300 
d1ek9a-  ( 193 )    LAaLnvenfktdkpqpvnallkeAekrnlsLlqarlsqdlAreqirqaqD
d1yc9a-  ( 280 )    h--it----ltsryv-------gllghRaditAarwraeAAaqqvgiaqa
d3pika-  ( 239 )    qtvns--dsLqsvklpaglsSqiLl-qrpdImeAehaLmaanAnIGaarA
d5azpa-  ( 244 )    rdlpa----ItkaLP--IgdPgeLlrrRPdIraaerrlaAstAdVGvatA
d5azsa-  ( 246 )    pgqr---pKLlqdiap--gtPseLierrPdIlaaehrLrArnadiGaarA
                                                aaaaaaaaaaaaaaaaaaaaaa

                             310       320       330       340       350 
d1ek9a-  ( 243 )    ghlptldltastgisdtsysgsktrgaag---tqyddsngqnkvglsfsl
d1yc9a-  ( 324 )    qfypdvtlsafigyqaf------------gldhlfdsgndagaigpaiyl
d3pika-  ( 286 )    affpsisltsgistass------------dlsslfnassgmwnfipkiei
d5azpa-  ( 288 )    dlfprvslsgflgftag------------rgsqigssaArawsvgpsisw
d5azsa-  ( 291 )    affprisltgsfgtssa------------emsglfdggsrswsflptltl
                        bbbbbbbbbbbb                       bbbbbbbbbb 

                             360       370       380       390       400 
d1ek9a-  ( 291 )    piyqgg-vnsqvkqaqynfvgaseqlesahrsVvqtVrsSfnnInasiss
d1yc9a-  ( 362 )    plftggrlegqltsaearyqeAvaqyngtlvqAlheiadvvtssqalqar
d3pika-  ( 324 )    pifnagrnqanldiaeirqqqsvvnYeqkIqnAfkeVadAlalrqslndq
d5azpa-  ( 326 )    aafdlgsVrarlrgakadadaalasYeqqvllAleeSanaFsdYgkrqer
d5azsa-  ( 329 )    pifdggrnranlslaearkdsavaaYegtIqtAfreVadalaasdtlrre
                           aaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa

                             410       420       430       440       450 
d1ek9a-  ( 341 )    Inaykqavvsaqssld-aeagysvgtrtIvdVLdaTttLynakqelAnar
d1yc9a-  ( 412 )    inkteqavqqaeqalhiatnrYqgglatYldVlvaEesllnnqralvnlq
d3pika-  ( 374 )    IsaqqrylaslqitlqraralyqhgavsYleVldaErslfaTrqtlldln
d5azpa-  ( 376 )    lvslvrqSeaSraaaqqaairYregttdFlvLldaereqlsAedaqAqAe
d5azsa-  ( 379 )    ekalralAnssnealklakaryesgvdnHlryLdaqrssflneiafidgs
                    aaaaaaaaaaaaaaaaaaaaaaa     aaaaaaaaaaaaaaaaaaaaaa

                             460       470       480      
d1ek9a-  ( 391 )    YnYlinqLniksalGtLneqdllalnnaLskpvsTnpe
d1yc9a-  ( 462 )    sraFsldLalIhAlgGGf                    
d3pika-  ( 424 )    yarqvneIsLYtaLgGG                     
d5azpa-  ( 426 )    velYrGIVaIYrSLGGGwqps                 
d5azsa-  ( 429 )    tqrqiaLVdLfrAlG                       
                    aaaaaaaaaaaaaa
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Integral outer membrane protein TolC, efflux pump componentOuter membrane efflux proteins (OEP)Escherichia coli [TaxId: 562]view
automated matchesautomated matchesVibrio cholerae [TaxId: 666]view
automated matchesautomated matchesEscherichia coli [TaxId: 562]view
automated matchesautomated matchesPseudomonas aeruginosa [TaxId: 208964]view
automated matchesautomated matchesPseudomonas aeruginosa [TaxId: 208964]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - E N L Q V Y Q Q A R L S N P E L R K S A A D R D A A F E K I N E A R S P L L P Q L G L G A D Y T Y S N G Y R - - - - - - - - - D A N G I N S N A T S A S L Q L T - Q S I - - F D S K W R A L T L Q E K A A G I Q D V T Y Q T D Q Q T L I L N T A T A Y F N V L N A I D V L S Y T Q A Q K E A I Y R Q L D Q T T Q R F N V G L V A I T D V Q N A R A Q Y D T V L A N E L T A R N N L D N A V E Q L R Q I T G - - - - - - - N Y Y P E L A A L N V E N F K T D K P Q P V N A L L K E A E K R N L S L L Q A R L S Q D L A R E Q I R Q A Q D G H L P T L D L T A S T G I S D T S Y S G S K T R G A A G - - - T Q Y D D S N G Q N K V G L S F S L P I Y Q G G - V N S Q V K Q A Q Y N F V G A S E Q L E S A H R S V V Q T V R S S F N N I N A S I S S I N A Y K Q A V V S A Q S S L D - A E A G Y S V G T R T I V D V L D A T T T L Y N A K Q E L A N A R Y N Y L I N Q L N I K S A L G T L N E Q D L L A L N N A L S K P V S T N P E
- - - - - - - - - - - - - - - - - - - - - - - - - - - - W P S A N W W Q R Y Q D A Q L N H L I E E A L Q H S P S L C M A M A R L K G A Q G F A R Q A G A I R S F D L G L A A S A T E S K V S E R Y Q S A T P P D - - - - G W N D Y G T L T L N F Q - Y D F D F W G K N R A A V V A A T S E L A A A E A E S V A A R L M I S T S I A N A Y A E L A R L Y A N Q E T V H A A L Q V R N K T V E L L E K R Y A N G L E T L G S V S Q A K A V A A S V E A E L L G I Q E S I Q L Q K N A L A A L V G Q G P D R A A S I E E P H - - I T - - - - L T S R Y V - - - - - - - G L L G H R A D I T A A R W R A E A A A Q Q V G I A Q A Q F Y P D V T L S A F I G Y Q A F - - - - - - - - - - - - G L D H L F D S G N D A G A I G P A I Y L P L F T G G R L E G Q L T S A E A R Y Q E A V A Q Y N G T L V Q A L H E I A D V V T S S Q A L Q A R I N K T E Q A V Q Q A E Q A L H I A T N R Y Q G G L A T Y L D V L V A E E S L L N N Q R A L V N L Q S R A F S L D L A L I H A L G G G F - - - - - - - - - - - - - - - - - - - -
C S L A P D Y Q R P A M P V P Q Q F S - - - - - - - - L Y Q N A G W R T F F V D N Q V K T L I S E A L V N N R D L R M A T L K V Q E A R A Q Y R L T D A D R Y P Q L N G E G S G S W S G N L - - - - - - K G N T - - - - A T T R E F S T G L N A S - F D L D F F G R L K N M S E A E R Q N Y L A T E E A Q R A V H I L L V S N V A Q S Y F N Q Q L A Y A Q L Q I A E E T L R N Y Q Q S Y A F V E K Q L L T G S S N V L A L E Q A R G V I E S T R S D I A K R Q G E L A Q A N N A L Q L L L G S - Y - - - G K L P Q A Q T V N S - - D S L Q S V K L P A G L S S Q I L L - Q R P D I M E A E H A L M A A N A N I G A A R A A F F P S I S L T S G I S T A S S - - - - - - - - - - - - D L S S L F N A S S G M W N F I P K I E I P I F N A G R N Q A N L D I A E I R Q Q Q S V V N Y E Q K I Q N A F K E V A D A L A L R Q S L N D Q I S A Q Q R Y L A S L Q I T L Q R A R A L Y Q H G A V S Y L E V L D A E R S L F A T R Q T L L D L N Y A R Q V N E I S L Y T A L G G G - - - - - - - - - - - - - - - - - - - - -
C T V G P D Y R T P D T A A A K I D A T A S K P Y D R S R F E S L W W K Q F D D P T L N Q L V E Q S L S G N R D L R V A F A R L R A A R A L R D D V A N D R F P V V T S R A S A D I G K G Q Q P G - - V T E D R - - - - V N S E R Y D L G L D S A - W E L D L F G R I R R Q L E S S D A L S E A A E A D L Q Q L Q V S L I A E L V D A Y G Q L R G A Q L R E K I A L S N L E N Q K E S R Q L T E Q L R D A G V G A E L D V L R A D A R L A A T A A S V P Q L Q A E A E R A R H R I A T L L G Q R P E E L T V D L S P R D L P A - - - - I T K A L P - - I G D P G E L L R R R P D I R A A E R R L A A S T A D V G V A T A D L F P R V S L S G F L G F T A G - - - - - - - - - - - - R G S Q I G S S A A R A W S V G P S I S W A A F D L G S V R A R L R G A K A D A D A A L A S Y E Q Q V L L A L E E S A N A F S D Y G K R Q E R L V S L V R Q S E A S R A A A Q Q A A I R Y R E G T T D F L V L L D A E R E Q L S A E D A Q A Q A E V E L Y R G I V A I Y R S L G G G W Q P S - - - - - - - - - - - - - - - - -
C S M A P T Y E R P A A P V A D S W S - - - - - - - - - - - - L D W K S F I V D A E L R R L V D M A L D N N R S L R Q T L L D I E A A R A Q Y R I Q R A D R V P G L N A A A T G N R Q R Q P A D - L S A G N R S - - - - E V A S S Y Q V G L A L P E Y E L D L F G R V K S L T D A A L Q Q Y L A S E E A A R A A R I A L V A E V S Q A Y L S Y D G A L R R L A L T R Q T L V S R E Y S F A L I D Q R R A A G A A T A L D Y Q E A L G L V E Q A R A E Q E R N L R Q K Q Q A F N A L V L L L G S - D D A A Q A I P R S P G Q R - - - P K L L Q D I A P - - G T P S E L I E R R P D I L A A E H R L R A R N A D I G A A R A A F F P R I S L T G S F G T S S A - - - - - - - - - - - - E M S G L F D G G S R S W S F L P T L T L P I F D G G R N R A N L S L A E A R K D S A V A A Y E G T I Q T A F R E V A D A L A A S D T L R R E E K A L R A L A N S S N E A L K L A K A R Y E S G V D N H L R Y L D A Q R S S F L N E I A F I D G S T Q R Q I A L V D L F R A L G - - - - - - - - - - - - - - - - - - - - - - -

 

 

 

 

 

Member Chain UniProtKB GO term
d1ek9a_ A P02930 GO:0005216
d1ek9a_ A P02930 GO:0005515
d1ek9a_ A P02930 GO:0009279
d1ek9a_ A P02930 GO:0009410
d1ek9a_ A P02930 GO:0009636
d1ek9a_ A P02930 GO:0014070
d1ek9a_ A P02930 GO:0015125
d1ek9a_ A P02930 GO:0015288
d1ek9a_ A P02930 GO:0015562
d1ek9a_ A P02930 GO:0015721
d1ek9a_ A P02930 GO:0016020
d1ek9a_ A P02930 GO:0019867
d1ek9a_ A P02930 GO:0030288
d1ek9a_ A P02930 GO:0034220
d1ek9a_ A P02930 GO:0042802
d1ek9a_ A P02930 GO:0042930
d1ek9a_ A P02930 GO:0042931
d1ek9a_ A P02930 GO:0046677
d1ek9a_ A P02930 GO:0055085
d1ek9a_ A P02930 GO:0098567
d1ek9a_ A P02930 GO:0140330
d1ek9a_ A P02930 GO:1990196
d1ek9a_ A P02930 GO:1990281
d1ek9a_ A P02930 GO:1990961
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in