BASE   PART 1   PART 2   PART 3  
Superfamily : 55331 [ Tautomerase/MIF ]
Class : Alpha and beta proteins (a+b)
Fold : Tautomerase/MIF
# of Members : 26
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1gyxa-  (   1 )        phidikcfprldeq-qkaalaaditdviirhln------skdssIs
d1hfoa-  (   1 )        PiFtLnTnik-atd-vpsdFlssTsalVgniLs------kpgsyVa
d1otga-  (   2 )        PhFiVeCSdnIreeAdLpgLfakVnptLaatg------iFplAgIr
d1u9da1  (   2 )        phLrFraVeahiVesLvptLlneLsslLs----------tarnaFt
d2aala1  (   1 )        PlLkFdLfygrtda-qiksLldAAhgAMvdAFg------vpandry
d2os5a-  (   1 )        PmVrVATnlp-dkd-VpanFeerLtdlLaeSMn------kprnrIa
d2x4ka1  (   1 )      mmpivnvkllegrsde-qlknlvsevtdavekttg------AnrqaIh
d2xcza-  (   1 )        PlInIqAsvp-ava-dansLlqeLsskLaelLg------kpekyVm
d3abfa-  (   1 )       mvvlkvtllegrppe-kkrelvr-lte-asrllg------epyeeVr
d3b64a-  (   1 )         pvITfVstpLdhh-krenLaqvYraVTrdvLg------kpedlVm
d3ej9a-  (   1 )        pmiscdmrygrtde-qkralsagllrviseatg------eprenIf
d3ej9b-  (   1 )        pfiechiatglsva-rkqqlirdvidvtnksig------sdpkiIn
d3gada-  (   2 )        pcCeLiTNisipdd-kaqnAlseIedaIsnvLg------kpvayIm
d3kana-  (   1 )        PfLeLdTnLp-anr-vpagLekrLcaaAasiLg------kpadrVn
d3t5sa1  (   1 )       mpcAiVtTnaft-------dqadaFcldMgvLat------gpvsyCm
d4dh4a-  (   1 )        PkCmIfCpvaAtpa-qqdaLlkdAekaVadALg------kplsyVm
d4fdxa-  (   1 )        piiqmnllegrtve-qkrnavaaiteavvrtld------vrpdqVr
d4grpa-  (   1 )    paaaAmFiVnTnVp-ras-vpdgFlseLtqqLaqaTg------KppqyIa
d4jj9a1  (   2 )        phLvIlySgNLdrdld-gavcrgLadal-tVrddegrqVfptggtr
d4lhpa-  (   1 )        PlIrIdLTsdrs---qrraIAdaVhdaLv-vLa------Ipardrf
d4lkba1  (   2 )        vqIkVyGLaekLnp-ikaeLsniLHtSLievlq------ispekrf
d6cuqa1  (   1 )       mphAlItLSAditee-ikkeIaheSmkILsevig-------pis-Ca
d6lr3a-  (   2 )        PvItVnTnva-eks-IpvfFqaaLtnmMtkaLq------kpkevMf
d6vvna1  (   1 )        ptlevylpqghave-rkasliqgltqatvdaig------apaesVr
d6vvna2  (  62 )        pviiailiagrtda-qkkaliaqlsetiaavld------aplqsTr
                         bbbbbb         aaaaaaaaaaaaaaaa         333 b

                             60        70        80        90        100 
d1gyxa-  (  41 )    ialqqiqpesw--qaiWdaeiapqme------------------------
d1hfoa-  (  39 )    Vhintdq--qlsfg-----------gstnpAAfgtLmSiggI-epsrnrd
d1otga-  (  42 )    Srvhwv--dtwqmadgq---------hdyAfVhMtLkIgagr-slesrqq
d1u9da1  (  38 )    felint---qyfae---------g----gvypVeVlWfg--r-eqqtqdq
d2aala1  (  40 )    Qtvsqhrpgemvle-----dtglgygrssaVVlLtViSrpr--seeqkvc
d2os5a-  (  39 )    IeVlAgq--rithg-----------asrnpVAvIkVeSigaL-saddnir
d2x4ka1  (  42 )    Vvieemkpnhygva------------------------------------
d2xcza-  (  39 )    tsLqCgv--pmtfs-----------gntepTCyVeVkSigaL-dgsrtqe
d3abfa-  (  41 )    VilyeVrrdqwaag------------------------------------
d3b64a-  (  40 )    mtfhdst--pmhff-----------gstdpVAcVrVealggy-gpsepek
d3ej9a-  (  40 )    fviregsGinfvqh------------------------------------
d3ej9b-  (  40 )    VlLvehaeanmsis------------------------------------
d3gada-  (  41 )    SnYdyqk--nlrfs-----------gsnegYCfVrLtSiggi-nrsnnss
d3kana-  (  39 )    Vtvrpgl--amaLs-----------gstepCAqLsIsSigvVgtaednrs
d3t5sa1  (  41 )    AgVrka---dmsfg-----------tstdlCCfVdfy-----------gn
d4dh4a-  (  40 )    vgYsqtg--qmrfg-----------gssdpCAfIrVaSiggi-tsstnck
d4fdxa-  (  40 )    Ilinelgvehfsva------------------------------------
d4grpa-  (  43 )    VhVvpdq--lmafg-----------gssepCAlCsLhSIgki-ggaqnrs
d4jj9a1  (  48 )    Vlaypa--phyaiadgGqagrdagesGdyGfAyLnLr-grgr-seavqrr
d4lhpa-  (  40 )    qiltahdpsdiiae-----daglgfqrspsVViIhVftqag--rtitkqr
d4lkba1  (  41 )    HrffpldkldFyyp-----s-----drtdnYLiIeIifegr--svetkkq
d6cuqa1  (  41 )    TqVvt-s--vggfg-----------g-ivkSAfIdIkS-sgL---gkqeg
d6lr3a-  (  40 )    VdlrSga--nimmg-----------gdrnpCVfAtVeCigrL-nptsnla
d6vvna1  (  40 )    IlLselpatnIglg------------------------------------
d6vvna2  ( 101 )    Vmikdipntdfgig------------------------------------
                    bbbb                                              

                             110       120       130       140       150 
d1gyxa-  (  65 )    --------------------------------------alikkpgysmna
d1hfoa-  (  75 )    HsakLfdhLntkL-gIpknr---MyIhfvnlngddvgw-ngttf      
d1otga-  (  80 )    agemLfelIkthFaalmesrlLaLsFeieelhptlnfkq---nnvhalfk
d1u9da1  (  70 )    IaqvItdqIrqllga---dshLaVvfiplq---------------rtayy
d2aala1  (  83 )    FyklLtgaLerdc-gIspdD---VivaLvensdadwsfgrgraeflt---
d2os5a-  (  75 )    HtqkItqfCqdTL-kLpkdk---ViItyfdlqpihvgf-ngttvaaa---
d2x4ka1  (  56 )    ----------------------------------------gvrksd    
d2xcza-  (  75 )    VselVcgHIeqnL-gIpadr---IyIgfedvparlwgw-ngstfg     
d3abfa-  (  55 )    ----------------------------------------gvlfsdkegt
d3b64a-  (  76 )    VtsiVtaaItkEC-gIvadr---IfVlyfspl--hcgw-ngtnf      
d3ej9a-  (  54 )    ----------------------------------------gehlpdyvp 
d3ej9b-  (  54 )    ----------------------------------------grih---ge 
d3gada-  (  77 )    LadkItkiLsnhL-gVkprr---VyIefrdcsaqnfaf-sgslfg     
d3kana-  (  76 )    hsahFfefLtkeL-aLgqdr---IlIrffpleswqigk-igtvmtfl   
d3t5sa1  (  74 )    psaaItgcLt--h-FVkper---VyIsfn                     
d4dh4a-  (  76 )    IaaaLsaACerhL-gVpknr---IyTtftnkspsewam-gdrtf      
d4fdxa-  (  54 )    ----------------------------------------gqtAamrq  
d4grpa-  (  79 )    YsklLcgLLaerL-rIspdr---VyInyydmnaanvgw-nnstfa     
d4jj9a1  (  95 )    AgetIaqaarallapLlqqrrVgltfqidvgaevydakf---gnlhalf 
d4lhpa-  (  84 )    VfaaItesLapi--gVagsD---VfIaitenaphdwsfgfgsaqYvt---
d4lkba1  (  80 )    LlrdIfkkVdekf-gisvyD---IeItlfeipkqnwgi-rgipgde    
d6cuqa1  (  75 )    LsdrYckLLeqkA-gIeggn---Iylnftemtgnnwgy-dhtf       
d6lr3a-  (  76 )    MardMedmFiehL-nVrrer---IvIrfipvpalfcsf-ngalh--d---
d6vvna1  (  54 )    ----------------------------------------gtltpsal  
d6vvna2  ( 115 )    ----------------------------------------gqtAralg-r
                                                                      

                          
d1gyxa-                   
d1hfoa-                   
d1otga-                   
d1u9da1  ( 102 )    ldgqhf
d2aala1  ( 126 )    gdlv  
d2os5a-  ( 117 )    ----tm
d2x4ka1                   
d2xcza-                   
d3abfa-                   
d3b64a-                   
d3ej9a-                   
d3ej9b-                   
d3gada-                   
d3kana-                   
d3t5sa1                   
d4dh4a-                   
d4fdxa-                   
d4grpa-                   
d4jj9a1                   
d4lhpa-  ( 126 )    gelaip
d4lkba1                   
d6cuqa1                   
d6lr3a-  ( 116 )    ----vs
d6vvna1                   
d6vvna2
 

 

Domain IDNameFamilySourceDomainSTRING-DB
4-oxalocrotonate tautomerase homologue YdcE4-oxalocrotonate tautomerase-likeEscherichia coli [TaxId: 562]view
Microphage migration inhibition factor (MIF)MIF-relatedTrichinella spiralis [TaxId: 6334]view
5-carboxymethyl-2-hydroxymuconate isomerase (CHMI)5-carboxymethyl-2-hydroxymuconate isomerase (CHMI)Escherichia coli [TaxId: 562]view
Hypothetical protein VC0714VC0714-likeVibrio cholerae [TaxId: 666]view
Malonate semialdehyde decarboxylase, MSADMSAD-likePseudomonas pavonaceae [TaxId: 47881]view
automated matchesautomated matchesAncylostoma ceylanicum [TaxId: 53326]view
automated matchesautomated matchesStaphylococcus aureus [TaxId: 1280]view
automated matchesautomated matchesProchlorococcus marinus [TaxId: 74547]view
automated matchesautomated matchesThermus thermophilus HB8 [TaxId: 300852]view
automated matchesautomated matchesLeishmania major [TaxId: 5664]view
automated matches4-oxalocrotonate tautomerase-likePseudomonas pavonaceae [TaxId: 47881]view
automated matches4-oxalocrotonate tautomerase-likePseudomonas pavonaceae [TaxId: 47881]view
Microphage migration inhibition factor (MIF)MIF-relatedPlasmodium yoelii [TaxId: 73239]view
D-dopachrome tautomeraseMIF-relatedHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesGiardia lamblia [TaxId: 184922]view
automated matchesautomated matchesToxoplasma gondii [TaxId: 5811]view
automated matchesautomated matchesMethylibium petroleiphilum [TaxId: 420662]view
Microphage migration inhibition factor (MIF)MIF-relatedHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesBordetella bronchiseptica [TaxId: 257310]view
automated matchesautomated matchesCoryneform bacterium [TaxId: 1728]view
automated matchesautomated matchesNostoc sp. [TaxId: 103690]view
automated matchesautomated matchesEntamoeba (Entamoeba histolytica) [TaxId: 5759]view
Microphage migration inhibition factor (MIF)MIF-relatedOncomelania hupensis [TaxId: 56141]view
automated matchesautomated matchesCaballeronia arationis [TaxId: 1777142]view
automated matchesautomated matchesCaballeronia arationis [TaxId: 1777142]view
Domain ID Name
d2orma-2orm A:
FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150
- - - - P H I D I K C F P R L D E Q - Q K A A L A A D I T D V I I R H L N - - - - - - S K D S S I S I A L Q Q I Q P E S W - - Q A I W D A E I A P Q M E - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - A L I K K P G Y S M N A - - - - - -
- - - - P I F T L N T N I K - A T D - V P S D F L S S T S A L V G N I L S - - - - - - K P G S Y V A V H I N T D Q - - Q L S F G - - - - - - - - - - - G S T N P A A F G T L M S I G G I - E P S R N R D H S A K L F D H L N T K L - G I P K N R - - - M Y I H F V N L N G D D V G W - N G T T F - - - - - - - - - - - -
- - - - P H F I V E C S D N I R E E A D L P G L F A K V N P T L A A T G - - - - - - I F P L A G I R S R V H W V - - D T W Q M A D G Q - - - - - - - - - H D Y A F V H M T L K I G A G R - S L E S R Q Q A G E M L F E L I K T H F A A L M E S R L L A L S F E I E E L H P T L N F K Q - - - N N V H A L F K - - - - - -
- - - - P H L R F R A V E A H I V E S L V P T L L N E L S S L L S - - - - - - - - - - T A R N A F T F E L I N T - - - Q Y F A E - - - - - - - - - G - - - - G V Y P V E V L W F G - - R - E Q Q T Q D Q I A Q V I T D Q I R Q L L G A - - - D S H L A V V F I P L Q - - - - - - - - - - - - - - - R T A Y Y L D G Q H F
- - - - P L L K F D L F Y G R T D A - Q I K S L L D A A H G A M V D A F G - - - - - - V P A N D R Y Q T V S Q H R P G E M V L E - - - - - D T G L G Y G R S S A V V L L T V I S R P R - - S E E Q K V C F Y K L L T G A L E R D C - G I S P D D - - - V I V A L V E N S D A D W S F G R G R A E F L T - - - G D L V - -
- - - - P M V R V A T N L P - D K D - V P A N F E E R L T D L L A E S M N - - - - - - K P R N R I A I E V L A G Q - - R I T H G - - - - - - - - - - - A S R N P V A V I K V E S I G A L - S A D D N I R H T Q K I T Q F C Q D T L - K L P K D K - - - V I I T Y F D L Q P I H V G F - N G T T V A A A - - - - - - - T M
- - M M P I V N V K L L E G R S D E - Q L K N L V S E V T D A V E K T T G - - - - - - A N R Q A I H V V I E E M K P N H Y G V A - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G V R K S D - - - - - - - - - -
- - - - P L I N I Q A S V P - A V A - D A N S L L Q E L S S K L A E L L G - - - - - - K P E K Y V M T S L Q C G V - - P M T F S - - - - - - - - - - - G N T E P T C Y V E V K S I G A L - D G S R T Q E V S E L V C G H I E Q N L - G I P A D R - - - I Y I G F E D V P A R L W G W - N G S T F G - - - - - - - - - - -
- - - M V V L K V T L L E G R P P E - K K R E L V R - L T E - A S R L L G - - - - - - E P Y E E V R V I L Y E V R R D Q W A A G - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G V L F S D K E G T - - - - - -
- - - - - P V I T F V S T P L D H H - K R E N L A Q V Y R A V T R D V L G - - - - - - K P E D L V M M T F H D S T - - P M H F F - - - - - - - - - - - G S T D P V A C V R V E A L G G Y - G P S E P E K V T S I V T A A I T K E C - G I V A D R - - - I F V L Y F S P L - - H C G W - N G T N F - - - - - - - - - - - -
- - - - P M I S C D M R Y G R T D E - Q K R A L S A G L L R V I S E A T G - - - - - - E P R E N I F F V I R E G S G I N F V Q H - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G E H L P D Y V P - - - - - - -
- - - - P F I E C H I A T G L S V A - R K Q Q L I R D V I D V T N K S I G - - - - - - S D P K I I N V L L V E H A E A N M S I S - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G R I H - - - G E - - - - - - -
- - - - P C C E L I T N I S I P D D - K A Q N A L S E I E D A I S N V L G - - - - - - K P V A Y I M S N Y D Y Q K - - N L R F S - - - - - - - - - - - G S N E G Y C F V R L T S I G G I - N R S N N S S L A D K I T K I L S N H L - G V K P R R - - - V Y I E F R D C S A Q N F A F - S G S L F G - - - - - - - - - - -
- - - - P F L E L D T N L P - A N R - V P A G L E K R L C A A A A S I L G - - - - - - K P A D R V N V T V R P G L - - A M A L S - - - - - - - - - - - G S T E P C A Q L S I S S I G V V G T A E D N R S H S A H F F E F L T K E L - A L G Q D R - - - I L I R F F P L E S W Q I G K - I G T V M T F L - - - - - - - - -
- - - M P C A I V T T N A F T - - - - - - - D Q A D A F C L D M G V L A T - - - - - - G P V S Y C M A G V R K A - - - D M S F G - - - - - - - - - - - T S T D L C C F V D F Y - - - - - - - - - - - G N P S A A I T G C L T - - H - F V K P E R - - - V Y I S F N - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - P K C M I F C P V A A T P A - Q Q D A L L K D A E K A V A D A L G - - - - - - K P L S Y V M V G Y S Q T G - - Q M R F G - - - - - - - - - - - G S S D P C A F I R V A S I G G I - T S S T N C K I A A A L S A A C E R H L - G V P K N R - - - I Y T T F T N K S P S E W A M - G D R T F - - - - - - - - - - - -
- - - - P I I Q M N L L E G R T V E - Q K R N A V A A I T E A V V R T L D - - - - - - V R P D Q V R I L I N E L G V E H F S V A - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G Q T A A M R Q - - - - - - - -
P A A A A M F I V N T N V P - R A S - V P D G F L S E L T Q Q L A Q A T G - - - - - - K P P Q Y I A V H V V P D Q - - L M A F G - - - - - - - - - - - G S S E P C A L C S L H S I G K I - G G A Q N R S Y S K L L C G L L A E R L - R I S P D R - - - V Y I N Y Y D M N A A N V G W - N N S T F A - - - - - - - - - - -
- - - - P H L V I L Y S G N L D R D L D - G A V C R G L A D A L - T V R D D E G R Q V F P T G G T R V L A Y P A - - P H Y A I A D G G Q A G R D A G E S G D Y G F A Y L N L R - G R G R - S E A V Q R R A G E T I A Q A A R A L L A P L L Q Q R R V G L T F Q I D V G A E V Y D A K F - - - G N L H A L F - - - - - - -
- - - - P L I R I D L T S D R S - - - Q R R A I A D A V H D A L V - V L A - - - - - - I P A R D R F Q I L T A H D P S D I I A E - - - - - D A G L G F Q R S P S V V I I H V F T Q A G - - R T I T K Q R V F A A I T E S L A P I - - G V A G S D - - - V F I A I T E N A P H D W S F G F G S A Q Y V T - - - G E L A I P
- - - - V Q I K V Y G L A E K L N P - I K A E L S N I L H T S L I E V L Q - - - - - - I S P E K R F H R F F P L D K L D F Y Y P - - - - - S - - - - - D R T D N Y L I I E I I F E G R - - S V E T K K Q L L R D I F K K V D E K F - G I S V Y D - - - I E I T L F E I P K Q N W G I - R G I P G D E - - - - - - - - - -
- - - M P H A L I T L S A D I T E E - I K K E I A H E S M K I L S E V I G - - - - - - - P I S - C A T Q V V T - S - - V G G F G - - - - - - - - - - - G - I V K S A F I D I K S - S G L - - - G K Q E G L S D R Y C K L L E Q K A - G I E G G N - - - I Y L N F T E M T G N N W G Y - D H T F - - - - - - - - - - - - -
- - - - P V I T V N T N V A - E K S - I P V F F Q A A L T N M M T K A L Q - - - - - - K P K E V M F V D L R S G A - - N I M M G - - - - - - - - - - - G D R N P C V F A T V E C I G R L - N P T S N L A M A R D M E D M F I E H L - N V R R E R - - - I V I R F I P V P A L F C S F - N G A L H - - D - - - - - - - V S
- - - - P T L E V Y L P Q G H A V E - R K A S L I Q G L T Q A T V D A I G - - - - - - A P A E S V R I L L S E L P A T N I G L G - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G T L T P S A L - - - - - - - -
- - - - P V I I A I L I A G R T D A - Q K K A L I A Q L S E T I A A V L D - - - - - - A P L Q S T R V M I K D I P N T D F G I G - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G Q T A R A L G - R - - - - - -

 

 

 

 

 

Member Chain UniProtKB GO term
d1gyxa_ A P31992 GO:0005737
d1gyxa_ A P31992 GO:0016853
d1gyxa_ A P31992 GO:0016862
d1gyxa_ A P31992 GO:0042803
d1gyxa_ A P31992 GO:0005737
d1gyxa_ A P31992 GO:0016853
d1gyxa_ A P31992 GO:0016862
d1gyxa_ A P31992 GO:0042803
d1hfoa_ A P81529 GO:0004167
d1hfoa_ A P81529 GO:0005125
d1hfoa_ A P81529 GO:0005576
d1hfoa_ A P81529 GO:0005615
d1hfoa_ A P81529 GO:0007165
d1hfoa_ A P81529 GO:0016853
d1hfoa_ A P81529 GO:0050178
d1hfoa_ A P81529 GO:0004167
d1hfoa_ A P81529 GO:0005125
d1hfoa_ A P81529 GO:0005576
d1hfoa_ A P81529 GO:0005615
d1hfoa_ A P81529 GO:0007165
d1hfoa_ A P81529 GO:0016853
d1hfoa_ A P81529 GO:0050178
d1hfoa_ A P81529 GO:0004167
d1hfoa_ A P81529 GO:0005125
d1hfoa_ A P81529 GO:0005576
d1hfoa_ A P81529 GO:0005615
d1hfoa_ A P81529 GO:0007165
d1hfoa_ A P81529 GO:0016853
d1hfoa_ A P81529 GO:0050178
d1otga_ A Q05354 GO:0008704
d1otga_ A Q05354 GO:0009056
d1otga_ A Q05354 GO:0016853
d1otga_ A Q05354 GO:0008704
d1otga_ A Q05354 GO:0009056
d1otga_ A Q05354 GO:0016853
d1otga_ A Q05354 GO:0008704
d1otga_ A Q05354 GO:0009056
d1otga_ A Q05354 GO:0016853
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in