Superfamily : 54695 [ POZ domain ]
Class : Alpha and beta proteins (a+b)
Fold : POZ domain
# of Members : 22
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1buoa-  (   6 )        m-gmiqlqnpshptgllckanqmrl-agtlCdVvImVd-----sqe
d1fs1b2  (   3 )                                       sikLqSsdg----ei
d1lqbb-  (  17 )                                      myVkLISsdg----he
d1nn7a-  (  42 )                                       livLnVsg-----tr
d1r29a-  (   7 )           s-qiqftrhasdvllnlnrlrs-rdilTdVvIvVs-----req
d2ppia1  (   6 )              avsdphaarllralssfrr-----fcahlvd-------ge
d2q81a1  (   2 )               dfpqhsqhvleqlnqqrq-lgllCdctfvvd-----gvh
d2vpka1  (   4 )                 shhcehll-rlnkqre-agflcdCtivig-----efq
d2z8ha1  (   1 )    msvsesavfayessvhstnvllslndqrk-kdvlCdVtVlVe-----gqr
d3drza-  (  43 )                                   s--kwVrLnVgg-----ty
d3ga1a-  (   3 )    q------tlqmeipnfgnsileclneqrl-qglyCdVsVvVk-----gha
d3kvta-  (  10 )                                      nrviInVgg-----ir
d3m4ta-  (   3 )        srklisatdiqysgsllnslneqrg-hGlfCdVtViVe-----drk
d3m5ba-  (   5 )           pirLpSpygsdrlvqlaarlrp---alCdTlItVg-----sqe
d4bgca1  (  52 )                                      ervvINIsg-----lr
d5bxda-  (  29 )                                   nap-vhidvGg------hm
d5ftaa-  (  30 )                                   s--syvklnvgg-----al
d5zb2b-  (   4 )                                      dfvtLvSkdd----ke
d6guwa-  (  11 )           sytyqvskhsaemlhnlngqrkdgGrfCdViLrVg-----ees
d6i0qa-  (  22 )                                   sFpevvelnvgg-----qv
d6n34a-  (   6 )           ylmfedenfiessvaklnalRk-sgqfCdVrLqVc-----ghe
d6w67a-  (  51 )           tfsytledhtkqafgimnelrl-sqqlCdVtLqVkyqdapaaq
                                                        bbbbb       bb

                             60        70        80        90        100 
d1buoa-  (  45 )    fhAhrtvLactSk-mFeilfhrns-----------qhytL--dflspkTF
d1fs1b2  (  14 )    feVdveiak-qsv-tiktmledl----------gmdpVplp--nvnaaiL
d1lqbb-  (  29 )    fivkrehAl-tSg-tIkamlsgpn------------evnFr--eIpshVL
d1nn7a-  (  52 )    fqtwqdtLerypdtLLGsserd-----ffyhpetq-qyfFd---rdpdIF
d1r29a-  (  43 )    frAhktvLmacSg-lFysiFtdqlkrnl-------svinLd-peinpeGF
d2ppia1  (  41 )    ipvq-niLaaaSp-yitkn----------ynps--------tylgisvvM
d2q81a1  (  35 )    fkAhkavLaacSe-YFkmlfvd--qkdv------v-----hldisnaaGL
d2vpka1  (  35 )    f-AHrnvlasfSe-yFgaiyrs--tsen------n--vfldqsqvkAdGF
d2z8ha1  (  45 )    frAhrsvLaacSs-yFhsrIvg--qtda------eLtvtLp-eeVtvkGF
d3drza-  (  55 )    flTtrqtLçrdpkSfLyrLÇqadpdLdsd-kdetg-AYlId---rdptyF
d3ga1a-  (  41 )    fkAhravLaasSs-yFrdlFnn--srsa--------vveLp-aaVqpqSF
d3kvta-  (  21 )    hetykatLkkipaTrLSrLtegm----lnydpvln-Eyffd---rhpgVF
d3m4ta-  (  43 )    frAHkniLsasSt-yFhqlFsvag-----------qvveL--sfIrAeIF
d3m5ba-  (  40 )    fpAhslvLagvsq-qLGrr----------------gqwaLg-egispstF
d4bgca1  (  63 )    fetql-tL-qfpeTLLGdprrm-----ryfdplrn-EyfFd---rnrpSF
d5bxda-  (  41 )    ytsslatLtkypeSrIGrlFdg--te-pivldslkqhYfid---rdGqMF
d5ftaa-  (  43 )    yyttmqtltkq-dtmlkaMlsgrmev---ltdseg-wilid---rcGkhF
d5zb2b-  (  16 )    yeIsrsAAm-iSp-tLka-----g------------rielk--qfdshIL
d6guwa-  (  49 )    fpAhkavLaacSe-yFesvfsc-----g-------keleM--htIspkVF
d6i0qa-  (  36 )    yftrhstlisiphSllwkmFsp--kandlakdskg-rffid---rdGflF
d6n34a-  (  43 )    mlAhravLaccSp-yLfeifns-----g------ishvkF--ddLnpeAV
d6w67a-  (  93 )    fmAhkvVLassSp-vFkamFtnglreqg------mevvsI--egIhpkvM
                    bbb aaaa      aaaaa                  bb       aaaa

                             110       120       130       140       150 
d1buoa-  (  81 )    qqILeyAYta----------tlq-akaeDlddLlyAAeiLeIeyLeeqcl
d1fs1b2  (  56 )    kkviqwcthhkdd                                     
d1lqbb-  (  71 )    skVcmyFtykvrytnssteipefpiapeialellmAanfLdc        
d1nn7a-  (  93 )    rHIlnfYrtg--LhYp-he---------cIsaYdeeLafFgLipeiIgdc
d1r29a-  (  84 )    niLLdfMYts----------rln-lregNimaVmaTAmyLqMehVvdtCr
d2ppia1  (  84 )    reILdyIFsg------------------qirtdVvaad-LlLtdLtlccl
d2q81a1  (  71 )    gqVLefMYta----------kls-lspenVddVlaVAtfLqMqdIitaCh
d2vpka1  (  74 )    qklleFiYtg----------tln-ldswnvkeihqAAdylkveevvtkCk
d2z8ha1  (  85 )    epLIqfAYta----------kLi-LskdnVdeVÇrCVefLsVhnIeesçf
d3drza-  ( 100 )    gpVLnyLrhg-klvInkdl---------aeegVleEAefYnI--tsLikl
d3ga1a-  (  79 )    qqILsfCYtg----------rls-mnvgdqdlLmyTAgfLqIqeImek  
d3kvta-  (  63 )    aqIInyYrsg-kLhYptdv---------cgplFeeeLefWgLdsnqVepc
d3m4ta-  (  79 )    aeILnyIYss----------kivrvrsdlldeLIkSGqlLgVkfIaelg 
d3m5ba-  (  72 )    aqLLnFVYG-----------esVeLqpgeLrpLqeAAraLgVqsLeeaCw
d4bgca1  ( 105 )    dAIlyYYqsgGrIrrpvnV---------pidiFseEIrfYqLgeeAmkFr
d5bxda-  (  85 )    ryILnFLrts-kllipddfk--------dytlLyeEAkyFqL--qpMlle
d5ftaa-  (  85 )    gtilnYlrdg-avplpsr----------eieellaeAkyYlv--qglvee
d5zb2b-  (  45 )    ekaveyLnynlkys-----ipefeiptemslelllAadyLsi        
d6guwa-  (  91 )    rdILdfAYts----------kIv-vrlecfpeLmtAAkfLlMrsVieiCq
d6i0qa-  (  83 )    ryildYlrdr-qvvlpdhfp--------ekgrlkreAeyFql--pdlvkl
d6n34a-  (  84 )    evLLnyAYta----------qlk-adkelvkdVysAAkkLkMdrVkqvCg
d6w67a-  ( 134 )    erLIefaYta----------sis-mgekcVlhVmnGAvmYqIdsVvraCa
                    aaaaaaaaa                    aaaaaaaaaa           

                             160 
d1buoa-  ( 120 )    kmletiq     
d1fs1b2                         
d1lqbb-                         
d1nn7a-  ( 133 )    cyeYkdrrrena
d1r29a-  ( 123 )    kfikas      
d2ppia1                         
d2q81a1  ( 110 )    alksl       
d2vpka1  ( 113 )    ikme        
d2z8ha1  ( 124 )    qflkfkfldsts
d3drza-  ( 138 )    Vkdkirer    
d3ga1a-                         
d3kvta-  ( 103 )    cwtyta      
d3m4ta-                         
d3m5ba-  ( 111 )    rar         
d4bgca1  ( 148 )    degfl       
d5bxda-  ( 124 )    Merwkq      
d5ftaa-  ( 124 )    Cqaalq      
d5zb2b-                         
d6guwa-  ( 130 )    evikqs      
d6i0qa-  ( 122 )    ltp         
d6n34a-  ( 123 )    dyllsrm     
d6w67a-  ( 173 )    dflvqql
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Promyelocytic leukaemia zinc finger (PLZF) protein BTB domainBTB/POZ domainHuman (Homo sapiens) [TaxId: 9606]view
Cyclin A/CDK2-associated p45, Skp1BTB/POZ domainHuman (Homo sapiens) [TaxId: 9606]view
Elongin CBTB/POZ domainHuman (Homo sapiens) [TaxId: 9606]view
Potassium channel kv4.2Tetramerization domain of potassium channelsNorway rat (Rattus norvegicus) [TaxId: 10116]view
B-cell lymphoma 6 (Bcl6) protein BTB domainBTB/POZ domainHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesMouse (Mus musculus) [TaxId: 10090]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view
akv3.1 voltage-gated potassium channelTetramerization domain of potassium channelsCalifornia sea hare (Aplysia californica) [TaxId: 6500]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view
automated matchesTetramerization domain of potassium channelsHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view
automated matchesBTB/POZ domainBaker's yeast (Saccharomyces cerevisiae) [TaxId: 559292]view
automated matchesautomated matchesZebrafish (Danio rerio) [TaxId: 7955]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160
- - - - M - G M I Q L Q N P S H P T G L L C K A N Q M R L - A G T L C D V V I M V D - - - - - S Q E F H A H R T V L A C T S K - M F E I L F H R N S - - - - - - - - - - - Q H Y T L - - D F L S P K T F Q Q I L E Y A Y T A - - - - - - - - - - T L Q - A K A E D L D D L L Y A A E I L E I E Y L E E Q C L K M L E T I Q - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - S I K L Q S S D G - - - - E I F E V D V E I A K - Q S V - T I K T M L E D L - - - - - - - - - - G M D P V P L P - - N V N A A I L K K V I Q W C T H H K D D - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - M Y V K L I S S D G - - - - H E F I V K R E H A L - T S G - T I K A M L S G P N - - - - - - - - - - - - E V N F R - - E I P S H V L S K V C M Y F T Y K V R Y T N S S T E I P E F P I A P E I A L E L L M A A N F L D C - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - L I V L N V S G - - - - - T R F Q T W Q D T L E R Y P D T L L G S S E R D - - - - - F F Y H P E T Q - Q Y F F D - - - R D P D I F R H I L N F Y R T G - - L H Y P - H E - - - - - - - - - C I S A Y D E E L A F F G L I P E I I G D C C Y E Y K D R R R E N A
- - - - - - - S - Q I Q F T R H A S D V L L N L N R L R S - R D I L T D V V I V V S - - - - - R E Q F R A H K T V L M A C S G - L F Y S I F T D Q L K R N L - - - - - - - S V I N L D - P E I N P E G F N I L L D F M Y T S - - - - - - - - - - R L N - L R E G N I M A V M A T A M Y L Q M E H V V D T C R K F I K A S - - - - - -
- - - - - - - - - - A V S D P H A A R L L R A L S S F R R - - - - - F C A H L V D - - - - - - - G E I P V Q - N I L A A A S P - Y I T K N - - - - - - - - - - Y N P S - - - - - - - - T Y L G I S V V M R E I L D Y I F S G - - - - - - - - - - - - - - - - - - Q I R T D V V A A D - L L L T D L T L C C L - - - - - - - - - - - -
- - - - - - - - - - - D F P Q H S Q H V L E Q L N Q Q R Q - L G L L C D C T F V V D - - - - - G V H F K A H K A V L A A C S E - Y F K M L F V D - - Q K D V - - - - - - V - - - - - H L D I S N A A G L G Q V L E F M Y T A - - - - - - - - - - K L S - L S P E N V D D V L A V A T F L Q M Q D I I T A C H A L K S L - - - - - - -
- - - - - - - - - - - - - S H H C E H L L - R L N K Q R E - A G F L C D C T I V I G - - - - - E F Q F - A H R N V L A S F S E - Y F G A I Y R S - - T S E N - - - - - - N - - V F L D Q S Q V K A D G F Q K L L E F I Y T G - - - - - - - - - - T L N - L D S W N V K E I H Q A A D Y L K V E E V V T K C K I K M E - - - - - - - -
M S V S E S A V F A Y E S S V H S T N V L L S L N D Q R K - K D V L C D V T V L V E - - - - - G Q R F R A H R S V L A A C S S - Y F H S R I V G - - Q T D A - - - - - - E L T V T L P - E E V T V K G F E P L I Q F A Y T A - - - - - - - - - - K L I - L S K D N V D E V C R C V E F L S V H N I E E S C F Q F L K F K F L D S T S
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - S - - K W V R L N V G G - - - - - T Y F L T T R Q T L C R D P K S F L Y R L C Q A D P D L D S D - K D E T G - A Y L I D - - - R D P T Y F G P V L N Y L R H G - K L V I N K D L - - - - - - - - - A E E G V L E E A E F Y N I - - T S L I K L V K D K I R E R - - - -
Q - - - - - - T L Q M E I P N F G N S I L E C L N E Q R L - Q G L Y C D V S V V V K - - - - - G H A F K A H R A V L A A S S S - Y F R D L F N N - - S R S A - - - - - - - - V V E L P - A A V Q P Q S F Q Q I L S F C Y T G - - - - - - - - - - R L S - M N V G D Q D L L M Y T A G F L Q I Q E I M E K - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - N R V I I N V G G - - - - - I R H E T Y K A T L K K I P A T R L S R L T E G M - - - - L N Y D P V L N - E Y F F D - - - R H P G V F A Q I I N Y Y R S G - K L H Y P T D V - - - - - - - - - C G P L F E E E L E F W G L D S N Q V E P C C W T Y T A - - - - - -
- - - - S R K L I S A T D I Q Y S G S L L N S L N E Q R G - H G L F C D V T V I V E - - - - - D R K F R A H K N I L S A S S T - Y F H Q L F S V A G - - - - - - - - - - - Q V V E L - - S F I R A E I F A E I L N Y I Y S S - - - - - - - - - - K I V R V R S D L L D E L I K S G Q L L G V K F I A E L G - - - - - - - - - - - - -
- - - - - - - P I R L P S P Y G S D R L V Q L A A R L R P - - - A L C D T L I T V G - - - - - S Q E F P A H S L V L A G V S Q - Q L G R R - - - - - - - - - - - - - - - - G Q W A L G - E G I S P S T F A Q L L N F V Y G - - - - - - - - - - - E S V E L Q P G E L R P L Q E A A R A L G V Q S L E E A C W R A R - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - E R V V I N I S G - - - - - L R F E T Q L - T L - Q F P E T L L G D P R R M - - - - - R Y F D P L R N - E Y F F D - - - R N R P S F D A I L Y Y Y Q S G G R I R R P V N V - - - - - - - - - P I D I F S E E I R F Y Q L G E E A M K F R D E G F L - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - N A P - V H I D V G G - - - - - - H M Y T S S L A T L T K Y P E S R I G R L F D G - - T E - P I V L D S L K Q H Y F I D - - - R D G Q M F R Y I L N F L R T S - K L L I P D D F K - - - - - - - - D Y T L L Y E E A K Y F Q L - - Q P M L L E M E R W K Q - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - S - - S Y V K L N V G G - - - - - A L Y Y T T M Q T L T K Q - D T M L K A M L S G R M E V - - - L T D S E G - W I L I D - - - R C G K H F G T I L N Y L R D G - A V P L P S R - - - - - - - - - - E I E E L L A E A K Y Y L V - - Q G L V E E C Q A A L Q - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - D F V T L V S K D D - - - - K E Y E I S R S A A M - I S P - T L K A - - - - - G - - - - - - - - - - - - R I E L K - - Q F D S H I L E K A V E Y L N Y N L K Y S - - - - - I P E F E I P T E M S L E L L L A A D Y L S I - - - - - - - - - - - - - - - - - - - -
- - - - - - - S Y T Y Q V S K H S A E M L H N L N G Q R K D G G R F C D V I L R V G - - - - - E E S F P A H K A V L A A C S E - Y F E S V F S C - - - - - G - - - - - - - K E L E M - - H T I S P K V F R D I L D F A Y T S - - - - - - - - - - K I V - V R L E C F P E L M T A A K F L L M R S V I E I C Q E V I K Q S - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - S F P E V V E L N V G G - - - - - Q V Y F T R H S T L I S I P H S L L W K M F S P - - K A N D L A K D S K G - R F F I D - - - R D G F L F R Y I L D Y L R D R - Q V V L P D H F P - - - - - - - - E K G R L K R E A E Y F Q L - - P D L V K L L T P - - - - - - - - -
- - - - - - - Y L M F E D E N F I E S S V A K L N A L R K - S G Q F C D V R L Q V C - - - - - G H E M L A H R A V L A C C S P - Y L F E I F N S - - - - - G - - - - - - I S H V K F - - D D L N P E A V E V L L N Y A Y T A - - - - - - - - - - Q L K - A D K E L V K D V Y S A A K K L K M D R V K Q V C G D Y L L S R M - - - - -
- - - - - - - T F S Y T L E D H T K Q A F G I M N E L R L - S Q Q L C D V T L Q V K Y Q D A P A A Q F M A H K V V L A S S S P - V F K A M F T N G L R E Q G - - - - - - M E V V S I - - E G I H P K V M E R L I E F A Y T A - - - - - - - - - - S I S - M G E K C V L H V M N G A V M Y Q I D S V V R A C A D F L V Q Q L - - - - -

 

 

 

 

 

Member Chain UniProtKB GO term
d1fs1b2 B Q13309 GO:0006511
d1fs1b2 B P63208 GO:0006511
d1fs1b2 B Q13309 GO:0006511
d1fs1b2 B P63208 GO:0006511
d1lqbb_ B Q15370 GO:0006511
d1lqbb_ B Q15369 GO:0006511
d1lqbb_ B P40337 GO:0006511
d1lqbb_ B Q16665 GO:0006511
d1lqbb_ B Q15370 GO:0006511
d1lqbb_ B Q15369 GO:0006511
d1lqbb_ B P40337 GO:0006511
d1lqbb_ B Q16665 GO:0006511
d1lqbb_ B Q15370 GO:0006511
d1lqbb_ B Q15369 GO:0006511
d1lqbb_ B P40337 GO:0006511
d1lqbb_ B Q16665 GO:0006511
d1nn7a_ A Q63881 GO:0005249
d1nn7a_ A Q63881 GO:0006813
d1nn7a_ A Q63881 GO:0008076
d1nn7a_ A Q63881 GO:0051260
d3kvta_ A O76457 GO:0005249
d3kvta_ A O76457 GO:0006813
d3kvta_ A O76457 GO:0008076
d3kvta_ A O76457 GO:0051260
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in