Superfamily : 53639 [ AraD/HMP-PK domain-like ]
Class : Alpha and beta proteins (a/b)
Fold : AraD/HMP-PK domain-like
# of Members : 9
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1e48p-  (   1 )         mernklArqIidtcleMtrl---gLNqgtaGnVSVryq-------
d1k0wa-  (   1 )          mledlkrqVLeaNlaLpkh---nLVtltwGnVSAVdre------
d1pvta-  (   2X)          ghreTireIqkVaywlaik---glseanaGnISVrld----erp
d2irpa-  (   2 )    nvelfkkfsekVeeIieaGriLhsr---gwVpatsGNISAkVse------
d2opib-  (   2 )          itdehielFlaqAhrYgda---kL-lcssgnLSwrig-------
d2pb9a1  ( 268 )          ekwrIyeeLtnavreFesinPvrLIPevGTnFVySlplpyAr--
d2phpa1  ( 241 )        yinkekViknLsyAiyllkk-nF-tLIPevGSNiAESlp--fPk--
d2v2ba-  (   2 )       qnItqSwFVqgMikATtdAwlk---gWDerngGnLTLrLddadiapy
d4c24a1  (   2 )             svkqeLikyGk-Lvet---dltg-tgGNLSvFdr-------
                             aaaaaaaaaaaaaaa            bbbbb         

                             60        70        80        90        100 
d1e48p-  (  36 )    ----------------------dgMLItPt-gipyekLt---eshIVfId
d1k0wa-  (  36 )    ---------------------rgVFVIKPs-gvdysiMt---addMVVVs
d1pvta-  (  37 )    egyevk--svneYgfdydgp--eYLLITat-g-SrreVyed-dskIClLH
d2irpa-  (  43 )    ----------------------eyIAITas-gkhKGkLt---pedIllId
d2opib-  (  36 )    ----------------------eeALISGt-gSwvptLa---kekVSiCn
d2pb9a1  ( 310 )    -------------------stkd-VAGVkgrIvkyg--------------
d2phpa1  ( 282 )    -------------------dfkd-VAALtgrIiknkl-------------
d2v2ba-  (  46 )    hdnfhqqpryipLsqpmplLantPFIVTGs-gkfFrnVqldpaanLGIVk
d4c24a1  (  35 )    ---------------------kqlMaITPs-gidFfeIk---esDIVvMd
                                            bbb                   bbb 

                             110       120       130       140       150 
d1e48p-  (  60 )    g---ngkhee------gklPSsqwrFHmaAYqsrp-----dAnAVVHNhA
d1k0wa-  (  61 )    i--etgevveg-----akkpssdtpTHrlLYqafp-----sIgGIVHThS
d1pvta-  (  82 )    vlp-gkhYeiLhGn---gkPTseFpTHLIHakFkenp---ekkAIVHThP
d2irpa-  (  67 )    y---eGrpvg------ggkpsaetlLHTtVYklfp-----eVnaVVHThS
d2opib-  (  60 )    i--asgtptn------gvkps-estFHLgvLrerp-----dVnVVLHFqS
d2pb9a1  ( 326 )    ------nsVkavgpVefGaSdhLArAVltY-rfyp-----eyrSAInIry
d2phpa1  ( 299 )    ------ggfyivgdiefGasehIAkiIlsASkfnp-----eirAC-nIky
d2v2ba-  (  95 )    VdsdGaGYhIlwGLtneavPTssLpaHFlSHcerikatngkDrVIMHChA
d4c24a1  (  60 )    i---nGnvveg-----erlpSsEwyMHLiQYqtrd-----dIdAIIHAhT
                                           aaaaaaaaaa          bbbb   

                             160       170       180       190       200 
d1e48p-  (  96 )    -vhCtaVSilnr------------sIpAIhfmIAaAggn--------sIp
d1k0wa-  (  99 )    -rhAtiWAqaGq------------sIpAtgttHAnyFyg--------tIP
d1pvta-  ( 127 )    -lnLltLnl------eefqeLlpk---kihpevlifFpq--------gis
d2irpa-  ( 103 )    -pnAtvISivekkd----------fVeledyellkaFpdIhthevkIkIP
d2opib-  (  97 )    -eyAtaiScknkpt----------nFnV-taeIPchVgs--------eIp
d2pb9a1  ( 365 )    sreIIeeiieiAer-------------------------------gfkvS
d2phpa1  ( 338 )    dggLIklLkd-----------------------------------kfaVs
d2v2ba-  ( 145 )    -tnLiaLTyvlendtavFTrqLWE----gsteCLvvFpd--------GVG
d4c24a1  (  97 )    -tyAtvLAclre------------pLpAShymIAvAg-k--------dVr
                     aaaaaaa                                          

                             210       220       230       240       250 
d1e48p-  ( 125 )    CApyat------fgtreLsehValaLk-------nrkATLLq----hhGL
d1k0wa-  ( 128 )    CTrkMtdaeingeyeweTGnVIvetFekqgidaaqMpGVLVh----shGP
d1pvta-  ( 162 )    vVefek------pGsveLGlkTvekSeg-------kdAVLWd----khgV
d2irpa-  ( 142 )    IFpneq------n-iplLakeVenyFktsed----kYGFLIr----ghGL
d2opib-  ( 128 )    vIpyyr------pgSpeLakaVvealk--------hnSvLLt----nhGQ
d2pb9a1  ( 385 )    fYdrreEpeika--gatipwGIetAIkri----erPDIIyhlgdvgkepI
d2phpa1  ( 353 )    sFdrkeeppn-----vstewGTkiACekfg---gVPdIIYDrGgegkepI
d2v2ba-  ( 182 )    Ilpwmv------pgtdaIgqaTAqeMqk-------HsLVLWP----fhGV
d4c24a1  ( 125 )    vA-yat------ygt-kLAvnAakaMe-------grrAVLLA----nhGI
                    b               aaaaaaaaa            bbbb        b

                             260       270       280       290       300 
d1e48p-  ( 158 )    IACevnLekAlwLAheVevLAqlYlttlaitdpVpvlsdeeIavvlekf 
d1k0wa-  ( 174 )    FAWgknAedAVhnaivLeeVAymgifcrqlapqlpdmqqtllnkhYlrkh
d1pvta-  ( 195 )    VAFGkdVaeAydRVeiLekaAeillrvlslg----rnptg          
d2irpa-  ( 177 )    YTWgrs-eeAliHTeaLEfIFecelklls---h                 
d2opib-  ( 161 )    VVcGkdfdqVyerAtfFe-ACriivqsgg---dysvltpeeiedleiyvl
d2pb9a1  ( 434 )    lVFGrnP-eVLekIkLi                                 
d2phpa1  ( 397 )    rVLGrdAieVvkkvevIqkiyntl                          
d2v2ba-  ( 215 )    FGSgptldeTfglIdtAekSAqvLvkvysmggmgqtisaaeLialGkrfg
d4c24a1  ( 158 )    LAGA-nLlnAfnIVeeVeyCAkiyclaknfg-epvvlpdeeMl-maekfk
                    bbbb  aaaaaaaaaaaaaaaaaaaaa                       

                             
d1e48p-                      
d1k0wa-                      
d1pvta-                      
d2irpa-                      
d2opib-  ( 208 )    gk       
d2pb9a1                      
d2phpa1                      
d2v2ba-  ( 265 )    vtplasAla
d4c24a1
 

 

Domain IDNameFamilySourceDomainSTRING-DB
L-fuculose-1-phosphate aldolaseAraD-like aldolase/epimeraseEscherichia coli [TaxId: 562]view
L-ribulose-5-phosphate 4-epimeraseAraD-like aldolase/epimeraseEscherichia coli [TaxId: 562]view
Putative sugar-phosphate aldolaseAraD-like aldolase/epimeraseThermotoga maritima [TaxId: 2336]view
automated matchesautomated matchesAquifex aeolicus [TaxId: 224324]view
automated matchesautomated matchesBacteroides thetaiotaomicron [TaxId: 226186]view
Phosphomethylpyrimidine kinasePhosphomethylpyrimidine kinase C-terminal domain-likePyrococcus furiosus [TaxId: 2261]view
Uncharacterized protein MJ0236Phosphomethylpyrimidine kinase C-terminal domain-likeMethanocaldococcus jannaschii [TaxId: 2190]view
automated matchesAraD-like aldolase/epimeraseEscherichia coli [TaxId: 562]view
automated matchesautomated matchesStreptococcus pneumoniae [TaxId: 170187]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300
- - - - - M E R N K L A R Q I I D T C L E M T R L - - - G L N Q G T A G N V S V R Y Q - - - - - - - - - - - - - - - - - - - - - - - - - - - - - D G M L I T P T - G I P Y E K L T - - - E S H I V F I D G - - - N G K H E E - - - - - - G K L P S S Q W R F H M A A Y Q S R P - - - - - D A N A V V H N H A - V H C T A V S I L N R - - - - - - - - - - - - S I P A I H F M I A A A G G N - - - - - - - - S I P C A P Y A T - - - - - - F G T R E L S E H V A L A L K - - - - - - - N R K A T L L Q - - - - H H G L I A C E V N L E K A L W L A H E V E V L A Q L Y L T T L A I T D P V P V L S D E E I A V V L E K F - - - - - - - - - -
- - - - - - M L E D L K R Q V L E A N L A L P K H - - - N L V T L T W G N V S A V D R E - - - - - - - - - - - - - - - - - - - - - - - - - - - R G V F V I K P S - G V D Y S I M T - - - A D D M V V V S I - - E T G E V V E G - - - - - A K K P S S D T P T H R L L Y Q A F P - - - - - S I G G I V H T H S - R H A T I W A Q A G Q - - - - - - - - - - - - S I P A T G T T H A N Y F Y G - - - - - - - - T I P C T R K M T D A E I N G E Y E W E T G N V I V E T F E K Q G I D A A Q M P G V L V H - - - - S H G P F A W G K N A E D A V H N A I V L E E V A Y M G I F C R Q L A P Q L P D M Q Q T L L N K H Y L R K H - - - - - - - - -
- - - - - - G H R E T I R E I Q K V A Y W L A I K - - - G L S E A N A G N I S V R L D - - - - E R P E G Y E V K - - S V N E Y G F D Y D G P - - E Y L L I T A T - G - S R R E V Y E D - D S K I C L L H V L P - G K H Y E I L H G N - - - G K P T S E F P T H L I H A K F K E N P - - - E K K A I V H T H P - L N L L T L N L - - - - - - E E F Q E L L P K - - - K I H P E V L I F F P Q - - - - - - - - G I S V V E F E K - - - - - - P G S V E L G L K T V E K S E G - - - - - - - K D A V L W D - - - - K H G V V A F G K D V A E A Y D R V E I L E K A A E I L L R V L S L G - - - - R N P T G - - - - - - - - - - - - - - - - - - -
N V E L F K K F S E K V E E I I E A G R I L H S R - - - G W V P A T S G N I S A K V S E - - - - - - - - - - - - - - - - - - - - - - - - - - - - E Y I A I T A S - G K H K G K L T - - - P E D I L L I D Y - - - E G R P V G - - - - - - G G K P S A E T L L H T T V Y K L F P - - - - - E V N A V V H T H S - P N A T V I S I V E K K D - - - - - - - - - - F V E L E D Y E L L K A F P D I H T H E V K I K I P I F P N E Q - - - - - - N - I P L L A K E V E N Y F K T S E D - - - - K Y G F L I R - - - - G H G L Y T W G R S - E E A L I H T E A L E F I F E C E L K L L S - - - H - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - I T D E H I E L F L A Q A H R Y G D A - - - K L - L C S S G N L S W R I G - - - - - - - - - - - - - - - - - - - - - - - - - - - - - E E A L I S G T - G S W V P T L A - - - K E K V S I C N I - - A S G T P T N - - - - - - G V K P S - E S T F H L G V L R E R P - - - - - D V N V V L H F Q S - E Y A T A I S C K N K P T - - - - - - - - - - N F N V - T A E I P C H V G S - - - - - - - - E I P V I P Y Y R - - - - - - P G S P E L A K A V V E A L K - - - - - - - - H N S V L L T - - - - N H G Q V V C G K D F D Q V Y E R A T F F E - A C R I I V Q S G G - - - D Y S V L T P E E I E D L E I Y V L G K - - - - - - -
- - - - - - E K W R I Y E E L T N A V R E F E S I N P V R L I P E V G T N F V Y S L P L P Y A R - - - - - - - - - - - - - - - - - - - - - S T K D - V A G V K G R I V K Y G - - - - - - - - - - - - - - - - - - - - N S V K A V G P V E F G A S D H L A R A V L T Y - R F Y P - - - - - E Y R S A I N I R Y S R E I I E E I I E I A E R - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G F K V S F Y D R R E E P E I K A - - G A T I P W G I E T A I K R I - - - - E R P D I I Y H L G D V G K E P I L V F G R N P - E V L E K I K L I - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - Y I N K E K V I K N L S Y A I Y L L K K - N F - T L I P E V G S N I A E S L P - - F P K - - - - - - - - - - - - - - - - - - - - - D F K D - V A A L T G R I I K N K L - - - - - - - - - - - - - - - - - - - G G F Y I V G D I E F G A S E H I A K I I L S A S K F N P - - - - - E I R A C - N I K Y D G G L I K L L K D - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - K F A V S S F D R K E E P P N - - - - - V S T E W G T K I A C E K F G - - - G V P D I I Y D R G G E G K E P I R V L G R D A I E V V K K V E V I Q K I Y N T L - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - Q N I T Q S W F V Q G M I K A T T D A W L K - - - G W D E R N G G N L T L R L D D A D I A P Y H D N F H Q Q P R Y I P L S Q P M P L L A N T P F I V T G S - G K F F R N V Q L D P A A N L G I V K V D S D G A G Y H I L W G L T N E A V P T S S L P A H F L S H C E R I K A T N G K D R V I M H C H A - T N L I A L T Y V L E N D T A V F T R Q L W E - - - - G S T E C L V V F P D - - - - - - - - G V G I L P W M V - - - - - - P G T D A I G Q A T A Q E M Q K - - - - - - - H S L V L W P - - - - F H G V F G S G P T L D E T F G L I D T A E K S A Q V L V K V Y S M G G M G Q T I S A A E L I A L G K R F G V T P L A S A L A
- - - - - - - - - S V K Q E L I K Y G K - L V E T - - - D L T G - T G G N L S V F D R - - - - - - - - - - - - - - - - - - - - - - - - - - - - K Q L M A I T P S - G I D F F E I K - - - E S D I V V M D I - - - N G N V V E G - - - - - E R L P S S E W Y M H L I Q Y Q T R D - - - - - D I D A I I H A H T - T Y A T V L A C L R E - - - - - - - - - - - - P L P A S H Y M I A V A G - K - - - - - - - - D V R V A - Y A T - - - - - - Y G T - K L A V N A A K A M E - - - - - - - G R R A V L L A - - - - N H G I L A G A - N L L N A F N I V E E V E Y C A K I Y C L A K N F G - E P V V L P D E E M L - M A E K F K - - - - - - - - -

 

 

 

 

 

Member Chain UniProtKB GO term
d1e48p_ P P0AB87 GO:0005829
d1e48p_ P P0AB87 GO:0005996
d1e48p_ P P0AB87 GO:0006004
d1e48p_ P P0AB87 GO:0008270
d1e48p_ P P0AB87 GO:0008738
d1e48p_ P P0AB87 GO:0016829
d1e48p_ P P0AB87 GO:0016830
d1e48p_ P P0AB87 GO:0016832
d1e48p_ P P0AB87 GO:0019317
d1e48p_ P P0AB87 GO:0019323
d1e48p_ P P0AB87 GO:0019568
d1e48p_ P P0AB87 GO:0019571
d1e48p_ P P0AB87 GO:0042355
d1e48p_ P P0AB87 GO:0046872
d1k0wa_ A P08203 GO:0003824
d1k0wa_ A P08203 GO:0005829
d1k0wa_ A P08203 GO:0005996
d1k0wa_ A P08203 GO:0008270
d1k0wa_ A P08203 GO:0008742
d1k0wa_ A P08203 GO:0016832
d1k0wa_ A P08203 GO:0016853
d1k0wa_ A P08203 GO:0019323
d1k0wa_ A P08203 GO:0019324
d1k0wa_ A P08203 GO:0019568
d1k0wa_ A P08203 GO:0019569
d1k0wa_ A P08203 GO:0019572
d1k0wa_ A P08203 GO:0032991
d1k0wa_ A P08203 GO:0042802
d1k0wa_ A P08203 GO:0046872
d1pvta_ A Q9X0G1 GO:0005829
d1pvta_ A Q9X0G1 GO:0016830
d1pvta_ A Q9X0G1 GO:0016832
d1pvta_ A Q9X0G1 GO:0019323
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in