Superfamily : 51726 [ UROD/MetE-like ]
Class : Alpha and beta proteins (a/b)
Fold : TIM beta/alpha-barrel
# of Members : 6
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1j93a-  (  10 )                       tqPlLLdAVrgkeVerPPVWLmrqaGr-ymk
d1r3ra-  (  11 )                   fpelkndtFlrAAwgeeTdyTPVWCMrQAgr-YLp
d2ejaa-  (   2 )                      pkndlLlrSLrgepIgrFPVWLMrQagr-yMp
d4ay7a-  (   7 )                     ftlktrLlaALkgepvdkvPVCSVTqTGI-v-e
d4l6ha1  (   1 )                                      mVqSSVLGFPriggqr
d4l6ha2  ( 404 )    dpvqerlttinealAtRkaaFpeRlteQakynlplFpTTTIGsFptn---
                                          aaaaa                       

                             60        70        80        90        100 
d1j93a-  (  40 )    syqllcekyp---lfrDrSenvdlVveISLQpWk-vfrPdGViLfS----
d1r3ra-  (  45 )    eFretraaq----dffsTCrspeaCCeLTlQPLr-rFpLDAAiIfS----
d2ejaa-  (  33 )    eyrkIrnrVk---nfleLCknvdlAteISllPlk-iLgVDAIiIfS----
d4ay7a-  (  38 )    LMdvv---gA---pWpeAHtnpelMAkLAlaNhe-lSgLeAVRLpY----
d4l6ha1  (  17 )    elkkiTeaywsgkAtveeLl--akGkelrehnWlQqagVdiIPSndFSyy
d4l6ha2  ( 460 )    --nkfa-----gqitaeyea--ineIetVVrfQe-eigLdVLVHGepERn
                    aaaaa                 aaaaaaaaaaaa        b       

                             110       120       130       140       150 
d1j93a-  (  82 )    -diLtPLsgMnIpFdiik-g------------------------------
d1r3ra-  (  86 )    -niLVVPqaLgMeVtmvp-g------------------------------
d2ejaa-  (  75 )    -diLVPLepLgVkVefve-g------------------------------
d4ay7a-  (  78 )    --lTVLVeAMgCeInmGtkn------------------------------
d4l6ha1  (  67 )    DqVLdLSllFnAiprYtkfdlapidvLFAMGrglaaaaavtaLemvWfdS
d4l6ha2  ( 504 )    dmVqyFGeqLngFaftt-----ngwvqsy-----g---------------
                                                                      

                             160       170       180       190       200 
d1j93a-  ( 100 )    -kgpvIfdpLrtaadVekVreF-iPeks--VpyVGeALtiLrkeVnnqAA
d1r3ra-  ( 104 )    -kgpsFpepLreeqdLerLrdpevVase--LgyVfqAItlTrqrLagrVP
d2ejaa-  (  93 )    -egpkL-swsg---kVsdLkkY--dpsq--NayVyeIIkrVkeaqd-eVP
d4ay7a-  (  96 )    -rqPsVtghpypk-dLegAaVpadLlqrgrIpvVleAIkiIrekVgpdvP
d4l6ha1  ( 126 )    nyhYVrPTFshs------tFLaa-------gikPvdeFneAkal-g--Vq
d4l6ha2  ( 529 )    --syvrpPiIvg------dVsrp-------kaMTvkeSvyAqsiTs--kp
                        b                           aaaaaaaaaaa       

                             210       220       230       240       250 
d1j93a-  ( 146 )    VLGfVGAPFTLASyVVEggssknFtkIkrLAfaepkvLhaLLqkFAtSMA
d1r3ra-  ( 151 )    LIGfAGAPWTLMTyMVegggsstMaqAkrWLyqrpqAShqLLriLTdALV
d2ejaa-  ( 133 )    VIGfAGAPFTLLSyLiegGaskdfksTklfMwenpkeYkrLMdiLTeTVL
d4ay7a-  ( 144 )    IVGGMEGPVtVASdLVs------vksFmkwsikktdlLeqALdiATeASi
d4l6ha1  ( 164 )    TRPvIlGPVSYLylG---kaddS-----------dlepisLLpkIlpvYk
d4l6ha2  ( 563 )    MKGMLTGPvTILrwS---fprd------------dvsgkiQAlQLGLALr
                     bbbbb aaaaaa                        aaaaaaaaaaaaa

                             260       270       280       290       300 
d1j93a-  ( 196 )    kYIryQAdsgAqAVQIfDSwATe--Ls---pvdFeeFSlpyLkqIVdsVk
d1r3ra-  ( 201 )    pYLvgQVvaGAqALQLfEshAgh--Lg---pqlFnkFAlpYIrdVAkqVk
d2ejaa-  ( 183 )    aYLkeQikAgAdVVQIfDswVnn--Ls---ledYgeyVypyVnyLIseLk
d4ay7a-  ( 188 )    iYAnAMveagAdVIAIaDpvASpdlMs---pdsFrqfLksrLqkFAssVn
d4l6ha1  ( 202 )    eLLqkLkeagAeqVQIdEPVLVldLp-----eavqskFkeAYdaL---vg
d4l6ha2  ( 598 )    dEVndLegagItVIQVdepAeGlplragkersdylnwAAqSFrVATSgVe
                    aaaaaaaa    bbbbb   3         aaaaaaa aaaaaaaa    

                             310       320       330       340       350 
d1j93a-  ( 241 )    lthp-----nlPLILYAs-gSggLLerLp----lTgVdVVSLDwtv---d
d1r3ra-  ( 246 )    arLreaglapvPMIIFAk-dGhfALeeLA----qAgYeVVGLDwtv---a
d2ejaa-  ( 228 )    dfs------dtpVIYFFr-gSssFidlAv----dYrAdALSVDwsv---d
d4ay7a-  ( 235 )    ----------svTVLHIcgnVnpILsdMA----dCgFeGLSVeekIg--s
d4l6ha1  ( 244 )    -------adVPeLiLTTYFg---dVrpNlaIen-LpVaGFHFDFvrVpeQ
d4l6ha2  ( 650 )    -------ns-TqIHSHfcdp---haLdADVvsi-spypNhGlGlfipps-
                                bbbb                      bbb         

                             360       370       380       390       400 
d1j93a-  ( 278 )    MadGrrrLgpnvAIQGnVdPg--vLfgskefItnrIndTvkkA-gkgkHI
d1r3ra-  ( 288 )    pkkArecVgktVTLQGNldPc--aLyaseeeIgqlVkqmLddF-gphrYI
d2ejaa-  ( 264 )    IPelFkiy--dkGFQGnLepa--vLyaseevIeekTlglLrrIpvktrYV
d4ay7a-  ( 269 )    AkkgkevIgtrArLVGnVsSpfTLlpGpvdkIkaeAkeALeg----gIdV
d4l6ha1  ( 284 )    LdeVAsiLkdgQtLSAGVVdGrniwktdfakasavVqkAikvgk---dVv
d4l6ha2  ( 717 )    FvsIl--ypaskfWVNPdcgltg-wpvsLtnMVaAkefray         
                    aaaaaa      bbb             aaaaaaaaaaa          b

                             410       420       430       440       450 
d1j93a-  ( 325 )    LNLGhGIkv----------------gTpeenFahFFeiAkglry      
d1r3ra-  ( 335 )    ANLGhGLyp----------------dMdpehVgaFVdaVhkhSrllrq  
d2ejaa-  ( 310 )    FNLGhGLap----------------dMelekVkyLVdlVksfplt     
d4ay7a-  ( 315 )    LAPGcgIap----------------mTpleNVkALvaARdefy----a  
d4l6ha1  ( 333 )    VATSSsLlhTpvdlsetldavidWfSfAtqKLdEVvvIAknvsgedVsql
d4l6ha2                                                               
                                                aaaaaaaaaaaa          

                             460    
d1j93a-                             
d1r3ra-                             
d2ejaa-                             
d4ay7a-                             
d4l6ha1  ( 387 )    eanaasiarsessitn
d4l6ha2
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Uroporphyrinogen decarboxylase, URODUroporphyrinogen decarboxylase, URODTobacco (Nicotiana tabacum), UROD-III [TaxId: 4097]view
Uroporphyrinogen decarboxylase, URODUroporphyrinogen decarboxylase, URODHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesAquifex aeolicus [TaxId: 63363]view
automated matchesautomated matchesMethanosarcina mazei [TaxId: 2209]view
automated matchesautomated matchesCandida albicans [TaxId: 237561]view
automated matchesautomated matchesCandida albicans [TaxId: 237561]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460
- - - - - - - - - - - - - - - - - - - T Q P L L L D A V R G K E V E R P P V W L M R Q A G R - Y M K S Y Q L L C E K Y P - - - L F R D R S E N V D L V V E I S L Q P W K - V F R P D G V I L F S - - - - - D I L T P L S G M N I P F D I I K - G - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - K G P V I F D P L R T A A D V E K V R E F - I P E K S - - V P Y V G E A L T I L R K E V N N Q A A V L G F V G A P F T L A S Y V V E G G S S K N F T K I K R L A F A E P K V L H A L L Q K F A T S M A K Y I R Y Q A D S G A Q A V Q I F D S W A T E - - L S - - - P V D F E E F S L P Y L K Q I V D S V K L T H P - - - - - N L P L I L Y A S - G S G G L L E R L P - - - - L T G V D V V S L D W T V - - - D M A D G R R R L G P N V A I Q G N V D P G - - V L F G S K E F I T N R I N D T V K K A - G K G K H I L N L G H G I K V - - - - - - - - - - - - - - - - G T P E E N F A H F F E I A K G L R Y - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - F P E L K N D T F L R A A W G E E T D Y T P V W C M R Q A G R - Y L P E F R E T R A A Q - - - - D F F S T C R S P E A C C E L T L Q P L R - R F P L D A A I I F S - - - - - N I L V V P Q A L G M E V T M V P - G - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - K G P S F P E P L R E E Q D L E R L R D P E V V A S E - - L G Y V F Q A I T L T R Q R L A G R V P L I G F A G A P W T L M T Y M V E G G G S S T M A Q A K R W L Y Q R P Q A S H Q L L R I L T D A L V P Y L V G Q V V A G A Q A L Q L F E S H A G H - - L G - - - P Q L F N K F A L P Y I R D V A K Q V K A R L R E A G L A P V P M I I F A K - D G H F A L E E L A - - - - Q A G Y E V V G L D W T V - - - A P K K A R E C V G K T V T L Q G N L D P C - - A L Y A S E E E I G Q L V K Q M L D D F - G P H R Y I A N L G H G L Y P - - - - - - - - - - - - - - - - D M D P E H V G A F V D A V H K H S R L L R Q - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - P K N D L L L R S L R G E P I G R F P V W L M R Q A G R - Y M P E Y R K I R N R V K - - - N F L E L C K N V D L A T E I S L L P L K - I L G V D A I I I F S - - - - - D I L V P L E P L G V K V E F V E - G - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - E G P K L - S W S G - - - K V S D L K K Y - - D P S Q - - N A Y V Y E I I K R V K E A Q D - E V P V I G F A G A P F T L L S Y L I E G G A S K D F K S T K L F M W E N P K E Y K R L M D I L T E T V L A Y L K E Q I K A G A D V V Q I F D S W V N N - - L S - - - L E D Y G E Y V Y P Y V N Y L I S E L K D F S - - - - - - D T P V I Y F F R - G S S S F I D L A V - - - - D Y R A D A L S V D W S V - - - D I P E L F K I Y - - D K G F Q G N L E P A - - V L Y A S E E V I E E K T L G L L R R I P V K T R Y V F N L G H G L A P - - - - - - - - - - - - - - - - D M E L E K V K Y L V D L V K S F P L T - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - F T L K T R L L A A L K G E P V D K V P V C S V T Q T G I - V - E L M D V V - - - G A - - - P W P E A H T N P E L M A K L A L A N H E - L S G L E A V R L P Y - - - - - - L T V L V E A M G C E I N M G T K N - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - R Q P S V T G H P Y P K - D L E G A A V P A D L L Q R G R I P V V L E A I K I I R E K V G P D V P I V G G M E G P V T V A S D L V S - - - - - - V K S F M K W S I K K T D L L E Q A L D I A T E A S I I Y A N A M V E A G A D V I A I A D P V A S P D L M S - - - P D S F R Q F L K S R L Q K F A S S V N - - - - - - - - - - S V T V L H I C G N V N P I L S D M A - - - - D C G F E G L S V E E K I G - - S A K K G K E V I G T R A R L V G N V S S P F T L L P G P V D K I K A E A K E A L E G - - - - G I D V L A P G C G I A P - - - - - - - - - - - - - - - - M T P L E N V K A L V A A R D E F Y - - - - A - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - M V Q S S V L G F P R I G G Q R E L K K I T E A Y W S G K A T V E E L L - - A K G K E L R E H N W L Q Q A G V D I I P S N D F S Y Y D Q V L D L S L L F N A I P R Y T K F D L A P I D V L F A M G R G L A A A A A V T A L E M V W F D S N Y H Y V R P T F S H S - - - - - - T F L A A - - - - - - - G I K P V D E F N E A K A L - G - - V Q T R P V I L G P V S Y L Y L G - - - K A D D S - - - - - - - - - - - D L E P I S L L P K I L P V Y K E L L Q K L K E A G A E Q V Q I D E P V L V L D L P - - - - - E A V Q S K F K E A Y D A L - - - V G - - - - - - - A D V P E L I L T T Y F G - - - D V R P N L A I E N - L P V A G F H F D F V R V P E Q L D E V A S I L K D G Q T L S A G V V D G R N I W K T D F A K A S A V V Q K A I K V G K - - - D V V V A T S S S L L H T P V D L S E T L D A V I D W F S F A T Q K L D E V V V I A K N V S G E D V S Q L E A N A A S I A R S E S S I T N
D P V Q E R L T T I N E A L A T R K A A F P E R L T E Q A K Y N L P L F P T T T I G S F P T N - - - - - N K F A - - - - - G Q I T A E Y E A - - I N E I E T V V R F Q E - E I G L D V L V H G E P E R N D M V Q Y F G E Q L N G F A F T T - - - - - N G W V Q S Y - - - - - G - - - - - - - - - - - - - - - - - S Y V R P P I I V G - - - - - - D V S R P - - - - - - - K A M T V K E S V Y A Q S I T S - - K P M K G M L T G P V T I L R W S - - - F P R D - - - - - - - - - - - - D V S G K I Q A L Q L G L A L R D E V N D L E G A G I T V I Q V D E P A E G L P L R A G K E R S D Y L N W A A Q S F R V A T S G V E - - - - - - - N S - T Q I H S H F C D P - - - H A L D A D V V S I - S P Y P N H G L G L F I P P S - F V S I L - - Y P A S K F W V N P D C G L T G - W P V S L T N M V A A K E F R A Y - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

 

 

 

 

 

Member Chain UniProtKB GO term
d1j93a_ A Q42967 GO:0004853
d1j93a_ A Q42967 GO:0006778
d1j93a_ A Q42967 GO:0006779
d1j93a_ A Q42967 GO:0006782
d1j93a_ A Q42967 GO:0009507
d1j93a_ A Q42967 GO:0015995
d1j93a_ A Q42967 GO:0016831
d1r3ra_ A P06132 GO:0004853
d1r3ra_ A P06132 GO:0005515
d1r3ra_ A P06132 GO:0005654
d1r3ra_ A P06132 GO:0005737
d1r3ra_ A P06132 GO:0005829
d1r3ra_ A P06132 GO:0006778
d1r3ra_ A P06132 GO:0006779
d1r3ra_ A P06132 GO:0006782
d1r3ra_ A P06132 GO:0006783
d1r3ra_ A P06132 GO:0006784
d1r3ra_ A P06132 GO:0006785
d1r3ra_ A P06132 GO:0006787
d1r3ra_ A P06132 GO:0016831
d1r3ra_ A P06132 GO:0042168
d1r3ra_ A P06132 GO:0048034
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in