Superfamily : 48256 [ Citrate synthase ]
Class : All alpha proteins
Fold : Citrate synthase
# of Members : 6
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d2p2wa-  (   1 )                                                      
d2r9ea-  (   3 )    t-------------------------------------------------
d3msua1  (   1 )    mevmlmskyatlkyadknIeieLpvyspslgndcidvssLvkh-------
d5uqsa-  (  31 )                                     tnLkdiLadlIpkeqar
d6s6fa-  (  16 )                                                      
d6wgya1  (   1 )                                                      
                                                                      

                             60        70        80        90        100 
d2p2wa-  (   1 )                       miqkglegvkicessICyLdginGrLyYrgi
d2r9ea-  (   4 )    ------------------eeiskgledvnikwtrlTtIdgnkGiLrYggy
d3msua1  (  44 )    ----------------giftydpgfmstaaceskITyidGgkGvLlHrgy
d5uqsa-  (  48 )    iktfrqqhgntvvgqitvdmmyggmrgmkglvYeTSvldp-deGIrFrgy
d6s6fa-  (  16 )                                vagqtaLStvgqegagLtYrgy
d6wgya1  (   1 )                    mtvpfvpgldgvvaftteIAepdkdggaLrYrgv
                                                       bbbb    bbbb  b

                             110       120       130       140       150 
d2p2wa-  (  32 )    pVeeLAe--------k-StFEeTAyFLWygklPtkseleeFkrkMAdyRe
d2r9ea-  (  36 )    sVediias-------g-aqDEeIQyLFLygnlPteqelrkYketVqkGYk
d3msua1  (  78 )    pIeeWTq--------k-snYrtLCYALIygelPtdeqvksFrqeiInkMp
d5uqsa-  (  97 )    sIpeCqkmLPkakggeEPLPEGLFWLLVTgqiPteeqVswLskeWAkrAa
d6s6fa-  (  38 )    dVrdLAa--------a-aiFEeVAyLLLygelPnkqqldaYlkkLqgqRd
d6wgya1  (  38 )    dIedLvs--------qrvtFgdVWALLVdgnfg---------sgLppaep
                    baaaaaa            aaaaaaaaaa     aaaaaaaaaaaa    

                             160       170       180       190       200 
d2p2wa-  (  73 )    LpaeAlgiLyhlpknlhYIdVLkiFLsih--------------------e
d2r9ea-  (  78 )    IpdfVinaIrqlpresdAVaMQmaAVaaMaasetkfkwn---------kd
d3msua1  ( 119 )    VcehVkaaIaampqhthPMsSLiaGVnvLaaehihngq----------ke
d5uqsa-  ( 147 )    LpshVvtmLdnfptnlhPMsQLsaAItaLnseSnFarayaegihrtkyWe
d6s6fa-  (  79 )    LpqaLkevLeripkdahpMdVMrtGAsvLgtlepEl--s---------fd
d6wgya1  (  71 )    fpLpihsg--------dvrvDVqaGLamLapiWgYa------pLldidda
                      aaaaaaa        aaaaaaaaaa                       

                             210       220       230       240       250 
d2p2wa-  ( 110 )    dlrekAIrVASvFPTILAYYyrYsk-g-keLirPr---kdLsHVeNFYyM
d2r9ea-  ( 119 )    tDrdvAAeMIGrMSAITVNVYRHIm-n-mpaelPk---psdsYAeSFLnA
d3msua1  ( 159 )    sqdeVAknIVAkIATIAAMAyRhnh-g-kkflePk---meygyAeNFLYM
d5uqsa-  ( 197 )    lIYeDCMdLIAkLPcVAAkIYrnLyregssigaid---skldWShNFTnM
d6s6fa-  ( 118 )    qqrdVADrLLAAFPAIMTYWyrftheg-qrIdCns---dEptIGGHFLaL
d6wgya1  ( 107 )    tArqqLArASVMALSYVAqsargi---yqpaVpqriIdecstvTarFMTr
                     aaaaaaaaaaaaaaaaaaaaaaa                  aaaaaaaa

                             260       270       280       290       300 
d2p2wa-  ( 155 )    Mfg----ern--ekirlLesAFILLMEQd-inaSTfaALviAStlsdLys
d2r9ea-  ( 164 )    Afg----rkAtkeeidAMntALILYTDHe-vpaSTtaGLvaVStlsdMYs
d3msua1  ( 204 )    MfAddesykPdelhikAMdTIFMLHADhe-qnaSTstVrlsGstgnSPYa
d5uqsa-  ( 244 )    Lgyt------daqFTeLMrLYLTIHSDheGgnvSAhtShlvGSalsDPYl
d6s6fa-  ( 164 )    Lhg----kkPselhvkVMNVSLILYAEhe-fnaSTftARvcAStlsdLYs
d6wgya1  ( 154 )    wqg-----ePdprhieAIdaYWVSAAEhg-mnaSTftARviAStgadVAa
                    aa         aaaaaaaaaaaaa        aaaaaaaaaa     aaa

                             310       320       330       340       350 
d2p2wa-  ( 198 )    CIvgALgaLkgplhGGaSekVPpMLeeIg-------sedrVeefVqk-Cl
d2r9ea-  ( 209 )    GItaALaaLkgplhGGaAeaAIaqFdeIk-------dpamVekwFndnIi
d3msua1  ( 253 )    AIiaGItaLwgpahGgaNeaVLkmLseIg-------stenidkyiakakd
d5uqsa-  ( 288 )    SFAaAMngLagplhGlanqeVLvwLtqLqkeVgkdvsdekLrdyIwn-TL
d6s6fa-  ( 209 )    CVtgAIgsLrgplhggaNeaAMelIerFs-------spqeAtaeLlk-ml
d6wgya1  ( 198 )    ALsgAIgaMsgplhgga-PaVlpmLdVea---------gdarsvVgldg-
                    aaaaaaaaa       aaaaaaaaa               aaaaaaa   

                             360       370       380       390       400 
d2p2wa-  ( 240 )    kekrkImGFghrvYktyDPRAvfLkrvLqehfpd-----sklFrIAskLe
d2r9ea-  ( 252 )    ngkkrLmGFghrvYktyDPRAkiFkgiAeklSskkpev-hkvyeIAtkLe
d3msua1  ( 296 )    ----klmGFghrvYkntDPrAtAMkknCeeilakLghsdnplLtVAkkle
d5uqsa-  ( 337 )    nsgrvVpgYghavLrktDprYtCQreFAlkhLphdpmF-kLVaqLykIVP
d6s6fa-  ( 251 )    erkdkImGFghaiYkdsDPrnevIkgwSkqLAdevg-d-kvlfaVSeaId
d6wgya1  ( 243 )    ----elmGFghrvYraeDPrArvLraAAerLgAp-----ryvAvaVeAAl
                                      aaaaaaaaaaaaa          aaaaaaaaa

                             410       420       430       440       450 
d2p2wa-  ( 285 )    eyIvsnki-kniyPnVdLYSSVLFeeLgFp--rnMFTALFATARVVGWTA
d2r9ea-  ( 301 )    dfGikafgskgiyPntDYFSGIVYmSIgFplrnnIYTALFALSRVTGWQA
d3msua1  ( 347 )    eiale----rklfSnVdFYSGIILkaMgIp--edMFTAIfALARTSGWIS
d5uqsa-  ( 386 )    nVlleqgkaknPwPnVdAHSGVLLqyYgM-temnYYTVLfGVSRALGVLA
d6s6fa-  ( 299 )    ktMweqk---klfpnAdFYHASAYhFMgIp--tkLFtPIfVCSRTSGWTA
d6wgya1  ( 287 )    selrrp---daieTnveFWAAVVLdfA-Vp--anMMpaMFtCGRTAGWCA
                    aaa             aaaaaaaaaa      333aaaaaaaaaaaaaaa

                             460       470       480       490 
d2p2wa-  ( 332 )    HVieyvs--dnklirptseyvgpmdveyipierrde     
d2r9ea-  ( 351 )    HFIeYve-eqqrlirpravyvgpaerkyvpiaer       
d3msua1  ( 397 )    QwieMvndpaqkigrprqlytgatnr--------nf     
d5uqsa-  ( 435 )    QLIWSRALg-fplerpk----------smstdgliklvdsk
d6s6fa-  ( 344 )    HVFeqRa--nnriirpsaeytgveqrafvpleqr       
d6wgya1  ( 335 )    HILeQkrlg--klvrpsaiyvgpgprspesvdgwervltta
                    aaaaaaa
 

 

Domain IDNameFamilySourceDomainSTRING-DB
automated matchesautomated matchesThermotoga maritima [TaxId: 2336]view
automated matchesCitrate synthaseThermoplasma acidophilum [TaxId: 2303]view
automated matchesautomated matchesFrancisella tularensis [TaxId: 263]view
automated matchesCitrate synthasePig (Sus scrofa) [TaxId: 9823]view
automated matchesautomated matchesPseudomonas aeruginosa [TaxId: 208964]view
automated matchesautomated matchesMycobacterium bovis [TaxId: 233413]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - M I Q K G L E G V K I C E S S I C Y L D G I N G R L Y Y R G I P V E E L A E - - - - - - - - K - S T F E E T A Y F L W Y G K L P T K S E L E E F K R K M A D Y R E L P A E A L G I L Y H L P K N L H Y I D V L K I F L S I H - - - - - - - - - - - - - - - - - - - - E D L R E K A I R V A S V F P T I L A Y Y Y R Y S K - G - K E L I R P R - - - K D L S H V E N F Y Y M M F G - - - - E R N - - E K I R L L E S A F I L L M E Q D - I N A S T F A A L V I A S T L S D L Y S C I V G A L G A L K G P L H G G A S E K V P P M L E E I G - - - - - - - S E D R V E E F V Q K - C L K E K R K I M G F G H R V Y K T Y D P R A V F L K R V L Q E H F P D - - - - - S K L F R I A S K L E E Y I V S N K I - K N I Y P N V D L Y S S V L F E E L G F P - - R N M F T A L F A T A R V V G W T A H V I E Y V S - - D N K L I R P T S E Y V G P M D V E Y I P I E R R D E - - - - -
T - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - E E I S K G L E D V N I K W T R L T T I D G N K G I L R Y G G Y S V E D I I A S - - - - - - - G - A Q D E E I Q Y L F L Y G N L P T E Q E L R K Y K E T V Q K G Y K I P D F V I N A I R Q L P R E S D A V A M Q M A A V A A M A A S E T K F K W N - - - - - - - - - K D T D R D V A A E M I G R M S A I T V N V Y R H I M - N - M P A E L P K - - - P S D S Y A E S F L N A A F G - - - - R K A T K E E I D A M N T A L I L Y T D H E - V P A S T T A G L V A V S T L S D M Y S G I T A A L A A L K G P L H G G A A E A A I A Q F D E I K - - - - - - - D P A M V E K W F N D N I I N G K K R L M G F G H R V Y K T Y D P R A K I F K G I A E K L S S K K P E V - H K V Y E I A T K L E D F G I K A F G S K G I Y P N T D Y F S G I V Y M S I G F P L R N N I Y T A L F A L S R V T G W Q A H F I E Y V E - E Q Q R L I R P R A V Y V G P A E R K Y V P I A E R - - - - - - -
M E V M L M S K Y A T L K Y A D K N I E I E L P V Y S P S L G N D C I D V S S L V K H - - - - - - - - - - - - - - - - - - - - - - - G I F T Y D P G F M S T A A C E S K I T Y I D G G K G V L L H R G Y P I E E W T Q - - - - - - - - K - S N Y R T L C Y A L I Y G E L P T D E Q V K S F R Q E I I N K M P V C E H V K A A I A A M P Q H T H P M S S L I A G V N V L A A E H I H N G Q - - - - - - - - - - K E S Q D E V A K N I V A K I A T I A A M A Y R H N H - G - K K F L E P K - - - M E Y G Y A E N F L Y M M F A D D E S Y K P D E L H I K A M D T I F M L H A D H E - Q N A S T S T V R L S G S T G N S P Y A A I I A G I T A L W G P A H G G A N E A V L K M L S E I G - - - - - - - S T E N I D K Y I A K A K D - - - - K L M G F G H R V Y K N T D P R A T A M K K N C E E I L A K L G H S D N P L L T V A K K L E E I A L E - - - - R K L F S N V D F Y S G I I L K A M G I P - - E D M F T A I F A L A R T S G W I S Q W I E M V N D P A Q K I G R P R Q L Y T G A T N R - - - - - - - - N F - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - T N L K D I L A D L I P K E Q A R I K T F R Q Q H G N T V V G Q I T V D M M Y G G M R G M K G L V Y E T S V L D P - D E G I R F R G Y S I P E C Q K M L P K A K G G E E P L P E G L F W L L V T G Q I P T E E Q V S W L S K E W A K R A A L P S H V V T M L D N F P T N L H P M S Q L S A A I T A L N S E S N F A R A Y A E G I H R T K Y W E L I Y E D C M D L I A K L P C V A A K I Y R N L Y R E G S S I G A I D - - - S K L D W S H N F T N M L G Y T - - - - - - D A Q F T E L M R L Y L T I H S D H E G G N V S A H T S H L V G S A L S D P Y L S F A A A M N G L A G P L H G L A N Q E V L V W L T Q L Q K E V G K D V S D E K L R D Y I W N - T L N S G R V V P G Y G H A V L R K T D P R Y T C Q R E F A L K H L P H D P M F - K L V A Q L Y K I V P N V L L E Q G K A K N P W P N V D A H S G V L L Q Y Y G M - T E M N Y Y T V L F G V S R A L G V L A Q L I W S R A L G - F P L E R P K - - - - - - - - - - S M S T D G L I K L V D S K
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - V A G Q T A L S T V G Q E G A G L T Y R G Y D V R D L A A - - - - - - - - A - A I F E E V A Y L L L Y G E L P N K Q Q L D A Y L K K L Q G Q R D L P Q A L K E V L E R I P K D A H P M D V M R T G A S V L G T L E P E L - - S - - - - - - - - - F D Q Q R D V A D R L L A A F P A I M T Y W Y R F T H E G - Q R I D C N S - - - D E P T I G G H F L A L L H G - - - - K K P S E L H V K V M N V S L I L Y A E H E - F N A S T F T A R V C A S T L S D L Y S C V T G A I G S L R G P L H G G A N E A A M E L I E R F S - - - - - - - S P Q E A T A E L L K - M L E R K D K I M G F G H A I Y K D S D P R N E V I K G W S K Q L A D E V G - D - K V L F A V S E A I D K T M W E Q K - - - K L F P N A D F Y H A S A Y H F M G I P - - T K L F T P I F V C S R T S G W T A H V F E Q R A - - N N R I I R P S A E Y T G V E Q R A F V P L E Q R - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - M T V P F V P G L D G V V A F T T E I A E P D K D G G A L R Y R G V D I E D L V S - - - - - - - - Q R V T F G D V W A L L V D G N F G - - - - - - - - - S G L P P A E P F P L P I H S G - - - - - - - - D V R V D V Q A G L A M L A P I W G Y A - - - - - - P L L D I D D A T A R Q Q L A R A S V M A L S Y V A Q S A R G I - - - Y Q P A V P Q R I I D E C S T V T A R F M T R W Q G - - - - - E P D P R H I E A I D A Y W V S A A E H G - M N A S T F T A R V I A S T G A D V A A A L S G A I G A M S G P L H G G A - P A V L P M L D V E A - - - - - - - - - G D A R S V V G L D G - - - - - E L M G F G H R V Y R A E D P R A R V L R A A A E R L G A P - - - - - R Y V A V A V E A A L S E L R R P - - - D A I E T N V E F W A A V V L D F A - V P - - A N M M P A M F T C G R T A G W C A H I L E Q K R L G - - K L V R P S A I Y V G P G P R S P E S V D G W E R V L T T A

 

 

 

 

 

Member Chain UniProtKB GO term
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in