Superfamily : 310581 [ PIWI domain N-terminal-like ]
Class : Alpha and beta proteins (a/b)
Fold : Phosphotyrosine protein phosphatases I-like
# of Members : 6
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1u04a3  ( 324 )    iaqelenkirvrddkgnsvpisqllwtnysrkYpvIlPyevpekfrkIre
d1yvua3  ( 315 )    kl---nfkdtvlDakgkntkvi--tnlrkFle--lCrP-fv-kkd---vL
d2bgga2  (  11 )            ltyrIgngasvpisntgelikgLr--nygPyevPsLk---yn
d4g0ma-  ( 586 )                                             s-----ivk
d4g0xa1  (   2 )                                       nkkingg-----tVn
d4krea2  ( 411 )       lpapilqYggrnraiAtPnqg-----vwdmrgkqFynGi-----eIk
                                                                      

                             60        70        80        90        100 
d1u04a3  ( 382 )    ipFIILDsgLl----adIqnfAtnEFreLvksy------yekvItedLns
d1yvua3  ( 353 )    sVEiIsVsv------wrkeeFLkeLinfLkn-kgI-kLkikgkslilaqt
d2bgga2  (  48 )    qIALIHnnqfs----slInqLksqIsskIdeVWhI-hnInIsefiYdsph
d4g0ma-  ( 590 )    hWAVLDFTaser-fnkMpndFvdnLidrCwrlgMqMe-apiVyktsrMet
d4g0xa1  (  13 )    nWICINFS--rqVqdnlArtfCqelAqcyvsgaFnp--epvlpPvsa---
d4krea2  ( 448 )    vWAIACFApqkqCreevLknFTdqLrkiSkdagMpIqgqpcfckyaq---
                     bbbbb          aaaaaaaaaaaaaa            bbb     

                             110       120       130       140       150 
d1u04a3  ( 453 )    dkgIieVveqVssfkgk---------elGlAFIAArnkLssekfeeIkrr
d1yvua3  ( 400 )    reEakeKlipVinKi-k---------dVdLVIVFLef----llydfVkre
d2bgga2  (  93 )    ---fdsIksqVdnAidt---------gVdGIMLVlPey-ntpLyykLksy
d4g0ma-  ( 638 )    LsngnaIeelLrsVideAsrkh-ggarPtLVLCAMsrkd--dgyktLkwI
d4g0xa1  (  58 )    --rpeqvekvLktryhdAtsklsqgkeIdLLIVILpdnng-sLygdLkrI
d4krea2  ( 495 )    --gadsVepmFrhLkntys-------gLqLIIVILpgk-t-pVyaeVkrV
                          aaaaaaa                bbbbbb       aaaaaaaa

                             160       170       180       190       200 
d1u04a3  ( 495 )    Lfn-lnViSQvVnedtLknkrdkydrnrLdlfvRhnlLfqvlsklgVkyy
d1yvua3  ( 446 )    Llk--kipSqVIlnrtLkne--------nlkfVlLnvAeqVLaktgNiPy
d2bgga2  ( 130 )    Lin--sipSqFMrydiLsnr--------nLtfyVdnlLvqFVskLgGkpw
d4g0ma-  ( 685 )    AetkLgLvTqcFlTgpAtk---------gGdqyranLAlkMnakv     
d4g0xa1  ( 105 )    CetelgIvSQcClTkhVfk---------s--kqyanValkInvkvgGrnt
d4krea2  ( 534 )    GdtlLgmaTQcvqvknVvk---------tspqtLsnlClkINvklgGinn
                    aa      bbbbbaaaa             aaaaaaaaaaaaaa      

                      
d1u04a3  ( 544 )    v 
d1yvua3  ( 487 )    k 
d2bgga2  ( 170 )    i 
d4g0ma-               
d4g0xa1  ( 146 )    vl
d4krea2  ( 575 )    i
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Argonaute homologue PF0537PIWI domain N-terminalPyrococcus furiosus [TaxId: 2261]view
Argonaute homologue Aq_1447PIWI domain N-terminalAquifex aeolicus [TaxId: 63363]view
Hypothetical protein AF1318PIWI domain N-terminalArchaeoglobus fulgidus [TaxId: 2234]view
automated matchesautomated matchesThale cress (Arabidopsis thaliana) [TaxId: 3702]view
automated matchesautomated matchesThale cress (Arabidopsis thaliana) [TaxId: 3702]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
I A Q E L E N K I R V R D D K G N S V P I S Q L L W T N Y S R K Y P V I L P Y E V P E K F R K I R E I P F I I L D S G L L - - - - A D I Q N F A T N E F R E L V K S Y - - - - - - Y E K V I T E D L N S D K G I I E V V E Q V S S F K G K - - - - - - - - - E L G L A F I A A R N K L S S E K F E E I K R R L F N - L N V I S Q V V N E D T L K N K R D K Y D R N R L D L F V R H N L L F Q V L S K L G V K Y Y V -
K L - - - N F K D T V L D A K G K N T K V I - - T N L R K F L E - - L C R P - F V - K K D - - - V L S V E I I S V S V - - - - - - W R K E E F L K E L I N F L K N - K G I - K L K I K G K S L I L A Q T R E E A K E K L I P V I N K I - K - - - - - - - - - D V D L V I V F L E F - - - - L L Y D F V K R E L L K - - K I P S Q V I L N R T L K N E - - - - - - - - N L K F V L L N V A E Q V L A K T G N I P Y K -
- - - - - - - - L T Y R I G N G A S V P I S N T G E L I K G L R - - N Y G P Y E V P S L K - - - Y N Q I A L I H N N Q F S - - - - S L I N Q L K S Q I S S K I D E V W H I - H N I N I S E F I Y D S P H - - - F D S I K S Q V D N A I D T - - - - - - - - - G V D G I M L V L P E Y - N T P L Y Y K L K S Y L I N - - S I P S Q F M R Y D I L S N R - - - - - - - - N L T F Y V D N L L V Q F V S K L G G K P W I -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - S - - - - - I V K H W A V L D F T A S E R - F N K M P N D F V D N L I D R C W R L G M Q M E - A P I V Y K T S R M E T L S N G N A I E E L L R S V I D E A S R K H - G G A R P T L V L C A M S R K D - - D G Y K T L K W I A E T K L G L V T Q C F L T G P A T K - - - - - - - - - G G D Q Y R A N L A L K M N A K V - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - N K K I N G G - - - - - T V N N W I C I N F S - - R Q V Q D N L A R T F C Q E L A Q C Y V S G A F N P - - E P V L P P V S A - - - - - R P E Q V E K V L K T R Y H D A T S K L S Q G K E I D L L I V I L P D N N G - S L Y G D L K R I C E T E L G I V S Q C C L T K H V F K - - - - - - - - - S - - K Q Y A N V A L K I N V K V G G R N T V L
- - - L P A P I L Q Y G G R N R A I A T P N Q G - - - - - V W D M R G K Q F Y N G I - - - - - E I K V W A I A C F A P Q K Q C R E E V L K N F T D Q L R K I S K D A G M P I Q G Q P C F C K Y A Q - - - - - G A D S V E P M F R H L K N T Y S - - - - - - - G L Q L I I V I L P G K - T - P V Y A E V K R V G D T L L G M A T Q C V Q V K N V V K - - - - - - - - - T S P Q T L S N L C L K I N V K L G G I N N I -

 

 

 

 

 

Member Chain UniProtKB GO term
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in