Superfamily : 100895 [ Kazal-type serine protease inhibitors ]
Class : Small proteins
Fold : Kazal-type serine protease inhibitors
# of Members : 13
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1h0za-  (   1 )                     esgkatsyaelÇneyrklvrngklaç--trend
d1hdla-  (   1 )                     k----nedqemçheFqafmkngklfÇpqdkkff
d1iw4a-  (   1 )                       ahmdçtefnplçrçnkmlgdliÇAvigd---
d1ldtl-  (   1I)                     kkvç-açp--------kil---kpvçGsdG---
d1nuba3  (  78 )                     çqdptsÇp--------apigefekVÇSndn---
d1pcea-  (   1 )    ekqvfsrmPiçehmtespdç--s----------riy---dpvÇGtdg---
d1r0ri-  (   6 )      vdçseypkp-----------açt--------ley---rpLÇGsdn---
d1r0tb-  (   2 )    vpmdçsrypnttseegkvmi--lçn--------kal---npVÇGtdg---
d2erwa1  (   4 )                     npç--aÇf--------rny---vpVçGsdg---
                                                             bb       

                             60        70        80        90        100 
d1h0za-  (  32 )    piqGpdgkvhg--ntÇsmÇevfFqaeeeekkk-----------kegesrn
d1hdla-  (  30 )    qs--ldgi--mfinkÇatÇkmilekeaksq                    
d1iw4a-  (  29 )    -ake----ehr--nmçalççehp--------gGfey-sngpçe       
d1ldtl-  (  19I)    ---r----tya--NsçiArçng-----------vsiksegsçp--tgIln
d1nuba3  ( 100 )    ---k----tfd--ssçhFfAtkçtlegtkkGhklhldyigpÇk--yi   
d1pcea-  (  33 )    ---v----tye--SeçklÇlarienkq-----diqivkdgeç        
d1r0ri-  (  29 )    ---k----tyg--nkçnFÇnavvesng-----tltlshfgkç        
d1r0tb-  (  36 )    ---v----tyd--NeÇvLÇahnleqgt-----svgkkhdgeç        
d2erwa1  (  21 )    ---k----Tyg--npçmlnçAaqtkvp-----gLklvhegrÇqrsnveqf
                            bb    aaaaaaaaaa
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Serine proteinase inhibitor lektiSerine proteinase inhibitor lektiHuman (Homo sapiens) [TaxId: 9606]view
Serine proteinase inhibitor lektiSerine proteinase inhibitor lektiHuman (Homo sapiens) [TaxId: 9606]view
Ascidian trypsin inhibitorOvomucoid domain III-likeSea squirt (Halocynthia roretzi) [TaxId: 7729]view
Leech derived tryptase inhibitor (LDTI-C)Ovomucoid domain III-likeMedicinal leech (Hirudo medicinalis) [TaxId: 6421]view
Domain of BM-40/SPARC/osteonectinOvomucoid domain III-likeHuman (Homo sapiens) [TaxId: 9606]view
PEC-60 peptideOvomucoid domain III-likePig (Sus scrofa) [TaxId: 9823]view
Ovomucoid domainsOvomucoid domain III-likeTurkey (Meleagris gallopavo) [TaxId: 9103]view
Ovomucoid domainsOvomucoid domain III-likeTurkey (Meleagris gallopavo) [TaxId: 9103]view
Blood-sucking insect-derived tryptase inhibitorOvomucoid domain III-likeTriatoma infestans [TaxId: 30076]view
Domain ID Name
d1lr7a21lr7 A:89-136
d6kbrc-6kbr C:
d1tgsi-1tgs I:
d2n71a-2n71 A:
FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100
- - - - - - - - - - - - - - - - - E S G K A T S Y A E L C N E Y R K L V R N G K L A C - - T R E N D P I Q G P D G K V H G - - N T C S M C E V F F Q A E E E E K K K - - - - - - - - - - - K E G E S R N
- - - - - - - - - - - - - - - - - K - - - - N E D Q E M C H E F Q A F M K N G K L F C P Q D K K F F Q S - - L D G I - - M F I N K C A T C K M I L E K E A K S Q - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - A H M D C T E F N P L C R C N K M L G D L I C A V I G D - - - - A K E - - - - E H R - - N M C A L C C E H P - - - - - - - - G G F E Y - S N G P C E - - - - - - -
- - - - - - - - - - - - - - - - - K K V C - A C P - - - - - - - - K I L - - - K P V C G S D G - - - - - - R - - - - T Y A - - N S C I A R C N G - - - - - - - - - - - V S I K S E G S C P - - T G I L N
- - - - - - - - - - - - - - - - - C Q D P T S C P - - - - - - - - A P I G E F E K V C S N D N - - - - - - K - - - - T F D - - S S C H F F A T K C T L E G T K K G H K L H L D Y I G P C K - - Y I - - -
E K Q V F S R M P I C E H M T E S P D C - - S - - - - - - - - - - R I Y - - - D P V C G T D G - - - - - - V - - - - T Y E - - S E C K L C L A R I E N K Q - - - - - D I Q I V K D G E C - - - - - - - -
- - V D C S E Y P K P - - - - - - - - - - - A C T - - - - - - - - L E Y - - - R P L C G S D N - - - - - - K - - - - T Y G - - N K C N F C N A V V E S N G - - - - - T L T L S H F G K C - - - - - - - -
V P M D C S R Y P N T T S E E G K V M I - - L C N - - - - - - - - K A L - - - N P V C G T D G - - - - - - V - - - - T Y D - - N E C V L C A H N L E Q G T - - - - - S V G K K H D G E C - - - - - - - -
- - - - - - - - - - - - - - - - - N P C - - A C F - - - - - - - - R N Y - - - V P V C G S D G - - - - - - K - - - - T Y G - - N P C M L N C A A Q T K V P - - - - - G L K L V H E G R C Q R S N V E Q F

 

 

 

 

 

Member Chain UniProtKB GO term
d1iw4a_ A P16589 GO:0004867
d1iw4a_ A P16589 GO:0005576
d1iw4a_ A P16589 GO:0010466
d1ldtl_ L P80424 GO:0004867
d1ldtl_ L P80424 GO:0010466
d1ldtl_ L P00761 GO:0004867
d1ldtl_ L P00761 GO:0010466
d1nuba3 A P09486 GO:0005509
d1nuba3 A P09486 GO:0005615
d1pcea_ A P37109 GO:0004867
d1pcea_ A P37109 GO:0005576
d1r0ri_ I P00780 GO:0004867
d1r0ri_ I P68390 GO:0004867
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in