Superfamily : 82109 [ MIR domain ]
Class : All beta proteins
Fold : beta-Trefoil
# of Members : 5
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1n4ka2  ( 236 )          ggdvvrLfHa----eqekFLTCdehr-----kkqhVFLrttgr-
d1t9fa1  (  22 )    dedfVtÇysvLkFiNA----ndgSrLHShdvkYgsgsgqqSVTAVk----
d1xzza1  (   7 )      sfLhigdiCSLYAeg---stnGFISTlg------lvddrCVVqpeagd
d3im6a-  (  13 )       fLrtddeVvLqCtAtihqqkLCLAAegg-------nrlCfLe---st
d3mala-  (  35 )      veITYGSaIKLmHe----ktkfrLHShdvpYgsgSgqqsVTGfp----
                             bbbbbb         bbbb             bbbb     

                             60        70        80        90        100 
d1n4ka2  ( 270 )    qsatsatsskAlWevevvq-------------------------------
d1t9fa1  (  64 )    ----nsddinSHWqIfpalna-----------------------------
d1xzza1  (  46 )    lnnpPkkfrDClFkLcpmnrYsaQkqfwkasttdavllnklhhaAdlekk
d3im6a-  (  53 )    ---sppdlsiCtFvLeqSlsvraLqemlant-------------------
d3mala-  (  75 )    ----gvvdsnSyWiVkpvpgt-----------------------------
                            333 bbbb                                  

                             110       120       130       140       150 
d1n4ka2  ( 302 )    ------------------lfrFkHlatghyLAAev-------dmvysLvS
d1t9fa1  (  81 )    ---kçn---rgdaikÇgdkIrLkHlttgtFLhShh-ftAPlskqhqEVSA
d1xzza1  ( 102 )    qnetenrkllgtvIqYgnvIQLlHlkSnkyLTVnkrlpAlleknAmrVtL
d3im6a-  (  86 )    -----------vtLlYghAILLrHsysgmyLCCls--t-----safdVGL
d3mala-  (  92 )    ---tek---qgdaVksgatIrLQHmktrkWLHShl-haSpisg-nlEVSC
                                      bbbbbb     bbbbbb          bbbbb

                             160       170       180       190       200 
d1n4ka2  ( 358 )    vpeGn--disSiFeldp---------------yvrLrHlctntwVhstni
d1t9fa1  ( 124 )    fgseaeSdtgDDWtViÇn------gdeWleseqFkLrHavtgSyLSLSgq
d1xzza1  ( 152 )    de---aGnegSwFyIqpfyklrsigdsVvigdkVvLnPvnAgqpLhASsh
d3im6a-  ( 150 )    qedtt--geaCWWtIhpas---segekVrvgddLILvSMsseryLhlsyg
d3mala-  ( 134 )    fgddtnsdtgDhWkLiIegs----gktWkqdqrVrLqHidtsGyLHShdk
                    b       333 bbbb                bbbbbb     bbbbbbb

                             210       220       230      
d1n4ka2  ( 405 )    piDkeeekpvmlkIGTsplkedkEaFaivpv       
d1t9fa1  ( 168 )    qfgrpih--gqrEVVGTdsitggSaWkVaeGi      
d1xzza1  ( 199 )    qLv-dnp--gCneVNSvncn---TSWkIvlf       
d3im6a-  ( 198 )    ------n--sswhVdAafqq---tlWsVap        
d3mala-  ( 180 )    kyqriag--gqQEVCGirekkadNIWlAaeGvylplne
                    b          bbbbbb        bbbb
 

 

Domain IDNameFamilySourceDomainSTRING-DB
IP3 receptor type 1 binding core, domain 1MIR domainMouse (Mus musculus) [TaxId: 10090]view
Hypothetical protein R12E2.13 (1D10)MIR domainNematode (Caenorhabditis elegans) [TaxId: 6239]view
IP3 receptor type 1 ligand binding suppressor domainRyanodine receptor N-terminal-likeMouse (Mus musculus) [TaxId: 10090]view
automated matchesRyanodine receptor N-terminal-likeMouse (Mus musculus) [TaxId: 10090]view
automated matchesautomated matchesThale cress (Arabidopsis thaliana) [TaxId: 3702]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230
- - - - - - G G D V V R L F H A - - - - E Q E K F L T C D E H R - - - - - K K Q H V F L R T T G R - Q S A T S A T S S K A L W E V E V V Q - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - L F R F K H L A T G H Y L A A E V - - - - - - - D M V Y S L V S V P E G N - - D I S S I F E L D P - - - - - - - - - - - - - - - Y V R L R H L C T N T W V H S T N I P I D K E E E K P V M L K I G T S P L K E D K E A F A I V P V - - - - - - -
D E D F V T C Y S V L K F I N A - - - - N D G S R L H S H D V K Y G S G S G Q Q S V T A V K - - - - - - - - N S D D I N S H W Q I F P A L N A - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - K C N - - - R G D A I K C G D K I R L K H L T T G T F L H S H H - F T A P L S K Q H Q E V S A F G S E A E S D T G D D W T V I C N - - - - - - G D E W L E S E Q F K L R H A V T G S Y L S L S G Q Q F G R P I H - - G Q R E V V G T D S I T G G S A W K V A E G I - - - - - -
- - S F L H I G D I C S L Y A E G - - - S T N G F I S T L G - - - - - - L V D D R C V V Q P E A G D L N N P P K K F R D C L F K L C P M N R Y S A Q K Q F W K A S T T D A V L L N K L H H A A D L E K K Q N E T E N R K L L G T V I Q Y G N V I Q L L H L K S N K Y L T V N K R L P A L L E K N A M R V T L D E - - - A G N E G S W F Y I Q P F Y K L R S I G D S V V I G D K V V L N P V N A G Q P L H A S S H Q L V - D N P - - G C N E V N S V N C N - - - T S W K I V L F - - - - - - -
- - - F L R T D D E V V L Q C T A T I H Q Q K L C L A A E G G - - - - - - - N R L C F L E - - - S T - - - S P P D L S I C T F V L E Q S L S V R A L Q E M L A N T - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - V T L L Y G H A I L L R H S Y S G M Y L C C L S - - T - - - - - S A F D V G L Q E D T T - - G E A C W W T I H P A S - - - S E G E K V R V G D D L I L V S M S S E R Y L H L S Y G - - - - - - N - - S S W H V D A A F Q Q - - - T L W S V A P - - - - - - - -
- - V E I T Y G S A I K L M H E - - - - K T K F R L H S H D V P Y G S G S G Q Q S V T G F P - - - - - - - - G V V D S N S Y W I V K P V P G T - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - T E K - - - Q G D A V K S G A T I R L Q H M K T R K W L H S H L - H A S P I S G - N L E V S C F G D D T N S D T G D H W K L I I E G S - - - - G K T W K Q D Q R V R L Q H I D T S G Y L H S H D K K Y Q R I A G - - G Q Q E V C G I R E K K A D N I W L A A E G V Y L P L N E

 

 

 

 

 

Member Chain UniProtKB GO term
d1n4ka2 A P11881 GO:0005220
d1n4ka2 A P11881 GO:0005262
d1n4ka2 A P11881 GO:0005783
d1n4ka2 A P11881 GO:0006816
d1n4ka2 A P11881 GO:0016020
d1n4ka2 A P11881 GO:0070588
d1n4ka2 A P11881 GO:0070679
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in