Superfamily : 81606 [ PP2C-like ]
Class : Alpha and beta proteins (a+b)
Fold : PP2C-like
# of Members : 7
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1txoa-  (   6 )                      lvLryaarsdrGlvranneDsvyAga------
d2j82a-  (1001 )                        mdVaGltdcGlirksnqDafyID---ekhq
d2jfra-  (   0 )                   gmasvlsaatatdqGpvrennqDaclad------g
d2pk0a1  (   1 )                        meiSlltdiGqrrsnnqDfInqfe-Nkagv
d3fxka1  (   2 )    gafldkpkmekhnaqgqgngLryGLSsMqGw-rvemeDahtAvigLpsg-
d6ihra1  (   1 )                         eAqfftdtGqhrdkneDaGgify-Nqtnq
d6jkva-  (   4 )                   nsVsyyrSasyshvGmvrkvnEDasLdA---pe-a
                                         bbbbbbb         bbbbbb       

                             60        70        80        90        100 
d1txoa-  (  32 )    ----rLLALAdG-gghaaGevaSqlViaaLa--hldd--d-epg-gdlla
d2j82a-  (1028 )    ----rFFIVAdGm---agGeeASrlAVdhIr--qyLethl-edlqhdpvt
d2jfra-  (  29 )    ----iLYAVAdGfg--arGhhASatALktLs--agfaa-------apdrd
d2pk0a1  (  30 )    ----pLIILAdGmgghrAGniASemTVtdLG--sdWaetd-fselseIrd
d3fxka1  (  50 )    leswSFFAVYdGhagsqvAkyCcehLldhItnnqdFkgsagapsvenVkn
d6ihra1  (  29 )    ----qLLVLCdGmgghkaGevASkfVtdeLk--srFeaen-lIeqhqAen
d6jkva-  (  35 )    ----gLWVVAdGmgghaaGdfVSslIvdtLr--ripaa----ssLpaYvg
                         bbbbbbbb     aaaaaaaaaaaaa  a             aaa

                             110       120       130       140       150 
d1txoa-  (  73 )    -LdaAVraGnsaIaaqv-eepdleg-gTTLTAILFag---nrLGLVHIGD
d2j82a-  (1071 )    LLrqAFlaAnhaIveqq-------dmGTTAVVILLde-kgdrAwCAHVGd
d2jfra-  (  64 )    gLleAVqqANlrVfelLgdep--tvSGTTLTAVAVFepgqggpLVVNIGd
d2pk0a1  (  73 )    wMlvsIetENrkIyelgqsd-dykgMGTTIEAVAIvg---dnIIFAHVGd
d3fxka1  ( 100 )    GIrtGFleIDehMrvmsekkhgadrSGSTAVGVLISp---qhTYFINCGd
d6ihra1  (  72 )    wLrnnIkdINfqLyhyAqenaeykgMGTTCVCALvfe---ksVVIANVGd
d6jkva-  (  75 )    aLrtgLaqVNerVrqeaglrg-vsvMGSTLVLLAArg---nqAsCLwAGd
                    aaaaaaaaaaaaaaaaa         bb bbbbbb      bbbbbbb  

                             160       170       180       190       200 
d1txoa-  ( 119 )    SrGYLlrdg-LtqITkddTfvqtlvdegritpeeahs-------hpqrsl
d2j82a-  (1120 )    SrIYrwr-dqLqqITsdhtw----------------------------ia
d2jfra-  ( 112 )    SPLYrIrdghMeqltddHSvAgelvrmgeitrheaRw-------hpqrhl
d2pk0a1  ( 119 )    SrIGIVrqgeYhllTsdhSlvnelvkagqlteeeaas-------hpq-ni
d3fxka1  ( 147 )    SrGLLCrnrkVhffTqdHkPsnplEk----erIqnAggsVmiqrVngsla
d6ihra1  ( 119 )    SrAYVInsrqieqITsdhSfVnhlvltgqitpeeaft-------hpqrni
d6jkva-  ( 121 )    SrLYrLrggvLeaiSrdhsyvqelldn---------h-------hpranv
                     bbbbb    bbb      aaaaaaa                        

                             210       220       230       240       250 
d1txoa-  ( 162 )    i-raLtGh---------------ev-Ptltr-eAr-agD-rYLLCSdGLS
d2j82a-  (1163 )    ls-CLGr-----------------lqIdIqpidLe-pgD-rLLLCSdGLT
d2jfra-  ( 155 )    ltrALGigp--------------higpdvfgIdCg-pgD-rLLISSdGLf
d2pk0a1  ( 162 )    itqsIGqan--------------pVepdlgvhlLe-egD-yLVVNSdGLT
d3fxka1  ( 193 )    VSrALGDfdyKcvhgkgpteQlVSPePeVhdierseedDqFIILACdGIW
d6ihra1  ( 162 )    itkvMGtdk--------------rVsPdLfikrln-fyd-yLLLNSdGLT
d6jkva-  ( 164 )    vtrAVGvhe--------------qLeLseaalhVl-pgD-SFLLCSdGLn
                                               bbbbbb       bbbbb aaaa

                             260       270       280       290       300 
d1txoa-  ( 195 )    dpVsd-tIleALqip-----eVa-SAhrLIelAlrggGpdNVTVVVAdLe
d2j82a-  (1197 )    eeLtddvIsiyLsep-----nVq-AAaaLVdAAkthgG-dnVTVVVIsv 
d2jfra-  ( 189 )    aaAdealIvdAAtSp-----dpqvAVrrLvevAndaggsdNTTVVVIdLg
d2pk0a1  ( 196 )    nmLsnadIAtvLtqe----ktLddKNqdLItlAnhrgGldNITVALVyve
d3fxka1  ( 243 )    dvMgneeLCdfVrsrLevtddLekVCneVVdtCLykgsrdNMSVILICFp
d6ihra1  ( 196 )    dyVkdneIkrlLvke----gtIedhGdqLmqlAldnhSkdNVTFILaaie
d6jkva-  ( 198 )    ktAddseLrdvLshs-----dPyaVVrsLVhlGltrgApdNITALVVrAf
                        aaaaaaaa         aaaaaaaaaaaaaa      bbbbbbb  

                        
d1txoa-  ( 240 )    h   
d2j82a-                 
d2jfra-                 
d2pk0a1  ( 242 )    s   
d3fxka1  ( 293 )    napk
d6ihra1  ( 242 )    g--v
d6jkva-
 

 

Domain IDNameFamilySourceDomainSTRING-DB
putative serine/threonine phosphatase pstp/pppPP2C-likeMycobacterium tuberculosis [TaxId: 1773]view
automated matchesautomated matchesSynechococcus elongatus [TaxId: 32046]view
automated matchesautomated matchesMycobacterium smegmatis [TaxId: 246196]view
automated matchesautomated matchesStreptococcus agalactiae [TaxId: 205921]view
automated matchesPP2C-likeHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesStaphylococcus aureus [TaxId: 1280]view
automated matchesautomated matchesPseudomonas aeruginosa [TaxId: 287]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300
- - - - - - - - - - - - - - - - - - L V L R Y A A R S D R G L V R A N N E D S V Y A G A - - - - - - - - - - R L L A L A D G - G G H A A G E V A S Q L V I A A L A - - H L D D - - D - E P G - G D L L A - L D A A V R A G N S A I A A Q V - E E P D L E G - G T T L T A I L F A G - - - N R L G L V H I G D S R G Y L L R D G - L T Q I T K D D T F V Q T L V D E G R I T P E E A H S - - - - - - - H P Q R S L I - R A L T G H - - - - - - - - - - - - - - - E V - P T L T R - E A R - A G D - R Y L L C S D G L S D P V S D - T I L E A L Q I P - - - - - E V A - S A H R L I E L A L R G G G P D N V T V V V A D L E H - - -
- - - - - - - - - - - - - - - - - - - - M D V A G L T D C G L I R K S N Q D A F Y I D - - - E K H Q - - - - R F F I V A D G M - - - A G G E E A S R L A V D H I R - - Q Y L E T H L - E D L Q H D P V T L L R Q A F L A A N H A I V E Q Q - - - - - - - D M G T T A V V I L L D E - K G D R A W C A H V G D S R I Y R W R - D Q L Q Q I T S D H T W - - - - - - - - - - - - - - - - - - - - - - - - - - - - I A L S - C L G R - - - - - - - - - - - - - - - - - L Q I D I Q P I D L E - P G D - R L L L C S D G L T E E L T D D V I S I Y L S E P - - - - - N V Q - A A A A L V D A A K T H G G - D N V T V V V I S V - - - - -
- - - - - - - - - - - - - - - G M A S V L S A A T A T D Q G P V R E N N Q D A C L A D - - - - - - G - - - - I L Y A V A D G F G - - A R G H H A S A T A L K T L S - - A G F A A - - - - - - - A P D R D G L L E A V Q Q A N L R V F E L L G D E P - - T V S G T T L T A V A V F E P G Q G G P L V V N I G D S P L Y R I R D G H M E Q L T D D H S V A G E L V R M G E I T R H E A R W - - - - - - - H P Q R H L L T R A L G I G P - - - - - - - - - - - - - - H I G P D V F G I D C G - P G D - R L L I S S D G L F A A A D E A L I V D A A T S P - - - - - D P Q V A V R R L V E V A N D A G G S D N T T V V V I D L G - - - -
- - - - - - - - - - - - - - - - - - - - M E I S L L T D I G Q R R S N N Q D F I N Q F E - N K A G V - - - - P L I I L A D G M G G H R A G N I A S E M T V T D L G - - S D W A E T D - F S E L S E I R D W M L V S I E T E N R K I Y E L G Q S D - D Y K G M G T T I E A V A I V G - - - D N I I F A H V G D S R I G I V R Q G E Y H L L T S D H S L V N E L V K A G Q L T E E E A A S - - - - - - - H P Q - N I I T Q S I G Q A N - - - - - - - - - - - - - - P V E P D L G V H L L E - E G D - Y L V V N S D G L T N M L S N A D I A T V L T Q E - - - - K T L D D K N Q D L I T L A N H R G G L D N I T V A L V Y V E S - - -
G A F L D K P K M E K H N A Q G Q G N G L R Y G L S S M Q G W - R V E M E D A H T A V I G L P S G - L E S W S F F A V Y D G H A G S Q V A K Y C C E H L L D H I T N N Q D F K G S A G A P S V E N V K N G I R T G F L E I D E H M R V M S E K K H G A D R S G S T A V G V L I S P - - - Q H T Y F I N C G D S R G L L C R N R K V H F F T Q D H K P S N P L E K - - - - E R I Q N A G G S V M I Q R V N G S L A V S R A L G D F D Y K C V H G K G P T E Q L V S P E P E V H D I E R S E E D D Q F I I L A C D G I W D V M G N E E L C D F V R S R L E V T D D L E K V C N E V V D T C L Y K G S R D N M S V I L I C F P N A P K
- - - - - - - - - - - - - - - - - - - - - E A Q F F T D T G Q H R D K N E D A G G I F Y - N Q T N Q - - - - Q L L V L C D G M G G H K A G E V A S K F V T D E L K - - S R F E A E N - L I E Q H Q A E N W L R N N I K D I N F Q L Y H Y A Q E N A E Y K G M G T T C V C A L V F E - - - K S V V I A N V G D S R A Y V I N S R Q I E Q I T S D H S F V N H L V L T G Q I T P E E A F T - - - - - - - H P Q R N I I T K V M G T D K - - - - - - - - - - - - - - R V S P D L F I K R L N - F Y D - Y L L L N S D G L T D Y V K D N E I K R L L V K E - - - - G T I E D H G D Q L M Q L A L D N H S K D N V T F I L A A I E G - - V
- - - - - - - - - - - - - - - N S V S Y Y R S A S Y S H V G M V R K V N E D A S L D A - - - P E - A - - - - G L W V V A D G M G G H A A G D F V S S L I V D T L R - - R I P A A - - - - S S L P A Y V G A L R T G L A Q V N E R V R Q E A G L R G - V S V M G S T L V L L A A R G - - - N Q A S C L W A G D S R L Y R L R G G V L E A I S R D H S Y V Q E L L D N - - - - - - - - - H - - - - - - - H P R A N V V T R A V G V H E - - - - - - - - - - - - - - Q L E L S E A A L H V L - P G D - S F L L C S D G L N K T A D D S E L R D V L S H S - - - - - D P Y A V V R S L V H L G L T R G A P D N I T A L V V R A F - - - -

 

 

 

 

 

Member Chain UniProtKB GO term
d1txoa_ A P9WHW5 GO:0004722
d1txoa_ A P9WHW5 GO:0006470
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in