Superfamily : 75304 [ Amidase signature (AS) enzymes ]
Class : Alpha and beta proteins (a/b)
Fold : Amidase signature (AS) enzymes
# of Members : 4
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1gr8a-  (   1 )                                               misLAdL
d1m22a-  (  42 )                                          pfpyaetdVadL
d2gi3a1  (   2 )                                         iDldFrkltIeeC
d3ppma-  (  33 )    grqkArgAatrArqkqrasletMdkaVqrfrlqnpdldseaLltlpLlqL
                                                                  aaaa

                             60        70        80        90        100 
d1gr8a-  (   8 )    qrrIetgelspnaAIaqShaaIearek---eVhAFvrhdks---------
d1m22a-  (  54 )    qarMtageldSttLTqaYlqrIaalDrtgprLrAVIelNpdAlkeAaerd
d2gi3a1  (  15 )    lkLs----eerekLPqlSLeTikrldp---hVkAFIsvrnv---------
d3ppma-  (  83 )    vqkLqsgelspeaVFftYLGkAwevnk---gTnCVTsYLtdCetqLsqAp
                    aaaaa     aaaaaaaaaaaaaaaaa   aa  bbbb            

                             110       120       130       140       150 
d1gr8a-  (  46 )    ---arAqasgpLrGIAVGIKDIIdTanMpTeMgSeIyrgwqPrsdApVVm
d1m22a-  ( 104 )    rerrdgrlrgpLHGIPLLLKDNINAapMATSAGSlALqgfrp-ddAyLVr
d2gi3a1  (  51 )    ----svekkgkfwGIPvAIKDNIlTlg-rTTCASrilenyeSvfDAtVVk
d3ppma-  ( 130 )    r-------qglLyGVPVSLKECFsYkghdSTLGLslnEgmpsesdCvVVq
                                   bbbbb              333         aaaa

                             160       170       180       190       200 
d1gr8a-  (  93 )    mLkraGATIIGKTtTTAFas------r--dpt---aTlNPhntghSPGGS
d1m22a-  ( 153 )    rLrdaGAVVLGKTNLSEWanfRGndsisGwSArGgqTrNPYrishSPcGS
d2gi3a1  (  97 )    k-keagfvvVgKANLDefag------sSTerSaffpTrNPwdlerVPGGS
d3ppma-  ( 173 )    VLklqGAVPFVHTNVPQSmf-----sYDCsNpLfgqTmNpwkssKSPGGS
                    aaaa   bbbbbb                                     

                             210       220       230       240       250 
d1gr8a-  ( 132 )    SSGSAAAVGAgMIPLALGTQtgGsVIRPAAYCgTAAIKPSfrmLptvgVk
d1m22a-  ( 203 )    SSGSAVAVAANLASVAIGtEtdGsIVcPAAINgVVGLKPTvGLVSrdGII
d2gi3a1  ( 142 )    SGGSAAAVSaG-VVAAlGSDtGGsVRqPASLCGVVGYKPTyGLVSrygLv
d3ppma-  ( 218 )    SGGEGALIGsgGSPLGLGTDigGsIRFPSAFCGICGLKPTGnRLSksgLk
                     aaaaaaaa     bbbbbb     aaaaaaa  bbbb            

                             260       270       280       290       300 
d1gr8a-  ( 182 )    cyS---waL-dTVGLFGarAeDLArGLlaMtgr----------------s
d1m22a-  ( 253 )    pIS---fsQ-dTAGPMARsVaDAAaVLtaIagrddadpaTatmpgravyd
d2gi3a1  ( 192 )    afA---ssL-DQIGPITKtVrDAAi-LeiisgrdendatTvn----rkvd
d3ppma-  ( 268 )    gCvygqtAVqlSLGPMArdVeSLAlCLkALLce-hLftldptVppl--pF
                               bbbbbb  aaaaaaaaaaa                    

                             310       320       330       340       350 
d1gr8a-  ( 212 )    eFsgiv--pakaPrIGVVrQefAgavepaAeqGLqaAikAAeragAsVqa
d1m22a-  ( 299 )    YtarldpqgLrgkrIGlLqt--pLlkyrgMpplIeqAateLrragAvVvp
d2gi3a1  ( 234 )    FlseIe--egvsgkFAVpeeIyehdIeegVserFeeAlkLLerlgAkver
d3ppma-  ( 315 )    reevYrss--rpLrVGyyetDnYTmPSpAMrrALieTkqrLeaagHtLip
                                 bbbb     3    aaaaaaaaaaaaaaaa   bbbb

                             360       370       380       390       400 
d1gr8a-  ( 260 )    idLpeaVheAwrIHpiIqdfEAHraLawEfs-------------------
d1m22a-  ( 347 )    veLpnqgaWae-aertLlLyEFkagLerYFnth-rAp--lrsLadLiafN
d2gi3a1  ( 283 )    vkI-phikySvaTyyvIapaeasst-----n-------------------
d3ppma-  ( 363 )    FlPnnIpyALevLSTGGlFsdGGrsFlqnFkgDfvDpCLgdlIliLrlps
                             aa aaaaaaaaaaaaa a                       

                             410       420       430       440       450 
d1gr8a-  ( 291 )    -ehhdeIapm--LrasLdatvglt----pkeydeArriGrrGr-re-Lge
d1m22a-  ( 393 )    qahskqElglf-gqelLveAdatagl-adpaYirarsdArrlAGpeGIda
d2gi3a1  ( 334 )    -vgfgevrrr--iigtftlsaayy----eayf-na-kvrrkIs-de-Lne
d3ppma-  ( 413 )    wfKrllslllkplfpRlAaflnnmrprsaeklwkLqheIemYr-qs-Via
                     a    a aa    aaaaaaa       aaaaaaaaaaaaaaa aa aaa

                             460       470       480       490       500 
d1gr8a-  ( 332 )    vFe--gVdVLLTYSAPGtApakala----sTgdprYNrLWTLMGNPCVNV
d1m22a-  ( 441 )    AlaahqLdALVAPTT-GvAwpir-------sfpgeSysAAAVAGyPSLTV
d2gi3a1  ( 377 )    vLs--qydAILTPTspvTAfkigeikdpltyyldifTIpANLAgLPAISV
d3ppma-  ( 461 )    qWkamnLdVLLTPML-GPALdln--tPgrAtGAvSYTmLYNCLdFPAGVV
                    aaa     bbbbb                        aaaaaa   bbbb

                             510       520       530       540       550 
d1gr8a-  ( 376 )    pVlkvg------------------------------gLPIGVQVIArfgn
d1m22a-  ( 487 )    PMgqid------------------------------glPVGLLFMGtaws
d2gi3a1  ( 426 )    PFGfsn------------------------------nLPVGVQVIGrrfa
d3ppma-  ( 508 )    pVttVtaeDdaqMelYkGyfgDiwDiiLkkAMknSvgLPVAVQCVAlpwq
                    bbbbb                                bbbbbbbb     

                             560       570      
d1gr8a-  ( 396 )    DahALaTAwfLedalak           
d1m22a-  ( 507 )    EpkLIeMAyAYeqrtr---arrpPhfdt
d2gi3a1  ( 446 )    DgkVFrIAraIEknSpyNengFplPeva
d3ppma-  ( 558 )    EElCLRFMreVeqlmtp--qkqp     
                    aaaaaaaaaaaaaaa
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Malonamidase E2Amidase signature (AS) enzymesBradyrhizobium japonicum [TaxId: 375]view
Peptide amidase PamAmidase signature (AS) enzymesStenotrophomonas maltophilia [TaxId: 40324]view
Glutamyl-tRNA(Gln) amidotransferase subunit AAmidase signature (AS) enzymesThermotoga maritima [TaxId: 2336]view
automated matchesAmidase signature (AS) enzymesNorway rat (Rattus norvegicus) [TaxId: 10116]view

 

No outliers

Created with Raphaëld3ppma-d1m22a-d2gi3a1d1gr8a-
FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

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- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - M I S L A D L Q R R I E T G E L S P N A A I A Q S H A A I E A R E K - - - E V H A F V R H D K S - - - - - - - - - - - - A R A Q A S G P L R G I A V G I K D I I D T A N M P T E M G S E I Y R G W Q P R S D A P V V M M L K R A G A T I I G K T T T T A F A S - - - - - - R - - D P T - - - A T L N P H N T G H S P G G S S S G S A A A V G A G M I P L A L G T Q T G G S V I R P A A Y C G T A A I K P S F R M L P T V G V K C Y S - - - W A L - D T V G L F G A R A E D L A R G L L A M T G R - - - - - - - - - - - - - - - - S E F S G I V - - P A K A P R I G V V R Q E F A G A V E P A A E Q G L Q A A I K A A E R A G A S V Q A I D L P E A V H E A W R I H P I I Q D F E A H R A L A W E F S - - - - - - - - - - - - - - - - - - - - E H H D E I A P M - - L R A S L D A T V G L T - - - - P K E Y D E A R R I G R R G R - R E - L G E V F E - - G V D V L L T Y S A P G T A P A K A L A - - - - S T G D P R Y N R L W T L M G N P C V N V P V L K V G - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G L P I G V Q V I A R F G N D A H A L A T A W F L E D A L A K - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - P F P Y A E T D V A D L Q A R M T A G E L D S T T L T Q A Y L Q R I A A L D R T G P R L R A V I E L N P D A L K E A A E R D R E R R D G R L R G P L H G I P L L L K D N I N A A P M A T S A G S L A L Q G F R P - D D A Y L V R R L R D A G A V V L G K T N L S E W A N F R G N D S I S G W S A R G G Q T R N P Y R I S H S P C G S S S G S A V A V A A N L A S V A I G T E T D G S I V C P A A I N G V V G L K P T V G L V S R D G I I P I S - - - F S Q - D T A G P M A R S V A D A A A V L T A I A G R D D A D P A T A T M P G R A V Y D Y T A R L D P Q G L R G K R I G L L Q T - - P L L K Y R G M P P L I E Q A A T E L R R A G A V V V P V E L P N Q G A W A E - A E R T L L L Y E F K A G L E R Y F N T H - R A P - - L R S L A D L I A F N Q A H S K Q E L G L F - G Q E L L V E A D A T A G L - A D P A Y I R A R S D A R R L A G P E G I D A A L A A H Q L D A L V A P T T - G V A W P I R - - - - - - - S F P G E S Y S A A A V A G Y P S L T V P M G Q I D - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G L P V G L L F M G T A W S E P K L I E M A Y A Y E Q R T R - - - A R R P P H F D T
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - I D L D F R K L T I E E C L K L S - - - - E E R E K L P Q L S L E T I K R L D P - - - H V K A F I S V R N V - - - - - - - - - - - - - S V E K K G K F W G I P V A I K D N I L T L G - R T T C A S R I L E N Y E S V F D A T V V K K - K E A G F V V V G K A N L D E F A G - - - - - - S S T E R S A F F P T R N P W D L E R V P G G S S G G S A A A V S A G - V V A A L G S D T G G S V R Q P A S L C G V V G Y K P T Y G L V S R Y G L V A F A - - - S S L - D Q I G P I T K T V R D A A I - L E I I S G R D E N D A T T V N - - - - R K V D F L S E I E - - E G V S G K F A V P E E I Y E H D I E E G V S E R F E E A L K L L E R L G A K V E R V K I - P H I K Y S V A T Y Y V I A P A E A S S T - - - - - N - - - - - - - - - - - - - - - - - - - - V G F G E V R R R - - I I G T F T L S A A Y Y - - - - E A Y F - N A - K V R R K I S - D E - L N E V L S - - Q Y D A I L T P T S P V T A F K I G E I K D P L T Y Y L D I F T I P A N L A G L P A I S V P F G F S N - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - N L P V G V Q V I G R R F A D G K V F R I A R A I E K N S P Y N E N G F P L P E V A
G R Q K A R G A A T R A R Q K Q R A S L E T M D K A V Q R F R L Q N P D L D S E A L L T L P L L Q L V Q K L Q S G E L S P E A V F F T Y L G K A W E V N K - - - G T N C V T S Y L T D C E T Q L S Q A P R - - - - - - - Q G L L Y G V P V S L K E C F S Y K G H D S T L G L S L N E G M P S E S D C V V V Q V L K L Q G A V P F V H T N V P Q S M F - - - - - S Y D C S N P L F G Q T M N P W K S S K S P G G S S G G E G A L I G S G G S P L G L G T D I G G S I R F P S A F C G I C G L K P T G N R L S K S G L K G C V Y G Q T A V Q L S L G P M A R D V E S L A L C L K A L L C E - H L F T L D P T V P P L - - P F R E E V Y R S S - - R P L R V G Y Y E T D N Y T M P S P A M R R A L I E T K Q R L E A A G H T L I P F L P N N I P Y A L E V L S T G G L F S D G G R S F L Q N F K G D F V D P C L G D L I L I L R L P S W F K R L L S L L L K P L F P R L A A F L N N M R P R S A E K L W K L Q H E I E M Y R - Q S - V I A Q W K A M N L D V L L T P M L - G P A L D L N - - T P G R A T G A V S Y T M L Y N C L D F P A G V V P V T T V T A E D D A Q M E L Y K G Y F G D I W D I I L K K A M K N S V G L P V A V Q C V A L P W Q E E L C L R F M R E V E Q L M T P - - Q K Q P - - - - -

 

 

 

 

 

 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in