Superfamily : 63829 [ Calcium-dependent phosphotriesterase ]
Class : All beta proteins
Fold : 6-bladed beta-propeller
# of Members : 6
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d2dg1a2  (   6 )    qdlptLfysgkSnsavPiises--------eLqtitAepwleIs-k---k
d2ghsa1  (  21 )                                   atvfpfagrvLd--e---t
d2p4oa1  (   4 )                 saglppiya--------dkpielapakiitsFp---v
d3o4pa-  (   1 )                                  mipvieplFtkvte-----d
d3srea-  (  18 )                    dqssfqtrFnvhreVtpvelpncnlvgId-----
d5gtqa-  (   2 )                                       gpvvekI---aeLgk
                                                           bb         

                             60        70        80        90        100 
d2dg1a2  (  44 )    gLqLEGLNFdr-qgqLFLLDvf-------egnIfkInPetkeikrpfvSh
d2ghsa1  (  35 )    plLgEgPtFdpasgTAwWFnIle-------reLHeLhlasg-ktv-haLp
d2p4oa1  (  30 )    ntfLEnLaSap-dgtIfVTnhe-------vGeIVsIt----pgqihatve
d3o4pa-  (  17 )    ipGAEGPvFDk-ngdFYivAPevevngkpaGeiLridlktgkktvickPe
d3srea-  (  50 )    -nGSEDLeILp-nGlAFISsgl-------sGkIllMdLnepavseleii-
d5gtqa-  (  14 )    ytvGEgPhWdhetqTLyFVDtve-------ktFHkYvpsqkkytf-Ckvd
                        bbbbb      bbbbb           bbbbb       bb bb  

                             110       120       130       140       150 
d2dg1a2  (  86 )    ----k---anPAAIkIhkd---grLFVCYLgdfkstGGIFAAtenG----
d2ghsa1  (  78 )    ---------FGSaLakis---dskQLIASd------dGLflRdtatg---
d2p4oa1  (  71 )    --------gkVSGLAft-----gdLVATgwna-dsiPvVslVksdg----
d3o4pa-  (  66 )    vngyg---GiPAGCqCdrd-a-nqlfvADMr-----lGllvvqtdG----
d3srea-  ( 104 )    gntLdissFnPhGISTfiddntvyLLVVNhpg--ssSTVEvFkFq-----
d5gtqa-  (  56 )    --------klVSFIIplag-spgrFVVSLe------reIAILtWdgvsaa
                                bbbb        bbbbb        bbbbb        

                             160       170       180       190       200 
d2dg1a2  ( 122 )    -dnlqdiiedls---tayCIDDMvFdskgGFYFTDfrgy---------s-
d2ghsa1  ( 108 )    --vltlhaeLesdlp-gnrSnDGr-HpsGAlWIGT-Grkae---------
d2p4oa1  ( 105 )    -t-vetLltlp----dAifLnGITPLsdtqYLTADSy-------------
d3o4pa-  ( 102 )    -t-feeiakkDsegrrMqGCndCaFDyeGnlWitAPAgevApadytrSm-
d3srea-  ( 148 )    esLlHltir-----hlLpSVNDIvAv-gphFYATNdhyfidpylkswEmh
d5gtqa-  (  91 )    PtsieaIvnVephik-nNrLndGkADplGnLWTGTmAidAglpi------
                       bbb               bbbb     bbbbb               

                             210       220       230       240       250 
d2dg1a2  ( 158 )    -tnplGGVYyVspdfrtvtpIiq--nIS-------VANGIALst----de
d2ghsa1  ( 146 )    --tgaGSIyHVa-kg-kvtkLfa--dIs-------iPNSICFsp----dG
d2p4oa1  ( 136 )    ----rGAIWlIdvvqpsGsiWlehpLarsnssvfpAANGLkrfg------
d3o4pa-  ( 149 )    -qekfGSiYCfttdg-qMiqvdt--aFq-------FPnGiAvRHmndgrp
d3srea-  ( 198 )    lglawSfVTYysp--ndvrvVa---gFd-------fANGInisp----dg
d5gtqa-  ( 134 )    -gpvtGsLYHLgadk-kvkmhes--nIa-------iANGLAWsn----dl
                         bbbbbb      bbbbbb  bb         bbbbbb        

                             260       270       280       290       300 
d2dg1a2  ( 194 )    kvLWVTETtanrLHrIaLeddgvtiqpfgatipyyFtg---heGPDSCcI
d2ghsa1  ( 179 )    ttGyfvdt-vnrl-rVpLdartGlptg-kaevfidst--gikgg-DGSVC
d2p4oa1  ( 178 )    nfLYVSNtek-lLLrIpVdstd-kpg--ePeiFve------qTnIdDFaF
d3o4pa-  ( 188 )    yqlivAEtptkklwSYdikg-pAkie--nkkvWGhipgt-hegGADGMdF
d3srea-  ( 233 )    kyVYIAeLLahkIhVyekhanw-tLtp----lvlsf-----dTLVdNIsV
d5gtqa-  ( 169 )    kkMYYIDSgkrrVDeYdYdastlsI-s-nqrpLFtFekheVpgyPdGQti
                     bbbbbb    bbbbbb                bb            bbb

                             310       320       330       340       350 
d2dg1a2  ( 241 )    Ds-ddNLYVAMy-gq------------GrVLVFnk-rG-ypIGqIlIpgr
d2ghsa1  ( 226 )    Da-eghIWnARw-ge------------gAVDrydt--dGnhiArYeVp--
d2p4oa1  ( 219 )    Dv-eGnLYGAT-hiy------------nsVVrIap-dr--sTtiIAqa--
d3o4pa-  ( 234 )    De-dnnllvAnw-gs------------shiEvFgp-dGgqPkmrirCpF-
d3srea-  ( 274 )    dpvtgdLWVGCHPNGmriffydanpPGSEVLrIqdIl-spvtvvyAenGt
d5gtqa-  ( 217 )    De-egnLWVAVf-qG------------qrIIkIstqqpevlldtvkIp--
                          bbbb                  bbbbb        bbbbb    

                             360       370       380       390       400 
d2dg1a2  ( 275 )    deghmlrSTHPqFipg---tnqLIICSNdiemg------------gGSmL
d2ghsa1  ( 258 )    -----GqTTCPAFIgp--dAsrLLVTSArehld----ddaitanpqhGLT
d2p4oa1  ( 250 )    -eqgViGSTAVaFGqtegdctAIYVVTNGGflpppt-------gvvpAnV
d3o4pa-  ( 268 )    -----ekPSnLHfkpq---tktiFVtEh--en---------------nAv
d3srea-  ( 327 )    ---vLqGSTVAavyk------gLLIGTvf------------------hkA
d5gtqa-  ( 251 )    ----DPQVTSVaFGGp--nldeLYVTSAglqlddssfd--kslVn--GhV
                           bbbbbb        bbbbbb                      b

                             410       420 
d2dg1a2  ( 310 )    YTVn-GFakghqsfQfq      
d2ghsa1  ( 298 )    FeLgi-eVkGrfeplYrl     
d2p4oa1  ( 293 )    VrLe-vgkpgyplg         
d3o4pa-  ( 293 )    wkFe-WqrnGkkqYCetlkfgif
d3srea-  ( 351 )    LyCdl                  
d5gtqa-  ( 291 )    YrVtgLgvkGfagvkVkl     
                    bbb
 

 

Domain IDNameFamilySourceDomainSTRING-DB
automated matchesSGL-likeStaphylococcus aureus [TaxId: 1280]view
RegucalcinSGL-likeAgrobacterium tumefaciens [TaxId: 358]view
Hypothetical protein All0351 homologueAll0351-likeNostoc punctiforme [TaxId: 272131]view
Diisopropylfluorophosphatase (phosphotriesterase, DFP)SGL-likeSquid (Loligo vulgaris) [TaxId: 6622]view
automated matchesSerum paraoxonase/arylesterase 1, PON1Artificial gene [TaxId: 32630]view
automated matchesautomated matchesFirefly (Photinus pyralis) [TaxId: 7054]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420
Q D L P T L F Y S G K S N S A V P I I S E S - - - - - - - - E L Q T I T A E P W L E I S - K - - - K G L Q L E G L N F D R - Q G Q L F L L D V F - - - - - - - E G N I F K I N P E T K E I K R P F V S H - - - - K - - - A N P A A I K I H K D - - - G R L F V C Y L G D F K S T G G I F A A T E N G - - - - - D N L Q D I I E D L S - - - T A Y C I D D M V F D S K G G F Y F T D F R G Y - - - - - - - - - S - - T N P L G G V Y Y V S P D F R T V T P I I Q - - N I S - - - - - - - V A N G I A L S T - - - - D E K V L W V T E T T A N R L H R I A L E D D G V T I Q P F G A T I P Y Y F T G - - - H E G P D S C C I D S - D D N L Y V A M Y - G Q - - - - - - - - - - - - G R V L V F N K - R G - Y P I G Q I L I P G R D E G H M L R S T H P Q F I P G - - - T N Q L I I C S N D I E M G - - - - - - - - - - - - G G S M L Y T V N - G F A K G H Q S F Q F Q - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - A T V F P F A G R V L D - - E - - - T P L L G E G P T F D P A S G T A W W F N I L E - - - - - - - R E L H E L H L A S G - K T V - H A L P - - - - - - - - - F G S A L A K I S - - - D S K Q L I A S D - - - - - - D G L F L R D T A T G - - - - - V L T L H A E L E S D L P - G N R S N D G R - H P S G A L W I G T - G R K A E - - - - - - - - - - - T G A G S I Y H V A - K G - K V T K L F A - - D I S - - - - - - - I P N S I C F S P - - - - D G T T G Y F V D T - V N R L - R V P L D A R T G L P T G - K A E V F I D S T - - G I K G G - D G S V C D A - E G H I W N A R W - G E - - - - - - - - - - - - G A V D R Y D T - - D G N H I A R Y E V P - - - - - - - G Q T T C P A F I G P - - D A S R L L V T S A R E H L D - - - - D D A I T A N P Q H G L T F E L G I - E V K G R F E P L Y R L - - - - -
- - - - - - - - - - - - - S A G L P P I Y A - - - - - - - - D K P I E L A P A K I I T S F P - - - V N T F L E N L A S A P - D G T I F V T N H E - - - - - - - V G E I V S I T - - - - P G Q I H A T V E - - - - - - - - G K V S G L A F T - - - - - G D L V A T G W N A - D S I P V V S L V K S D G - - - - - T - V E T L L T L P - - - - D A I F L N G I T P L S D T Q Y L T A D S Y - - - - - - - - - - - - - - - - - R G A I W L I D V V Q P S G S I W L E H P L A R S N S S V F P A A N G L K R F G - - - - - - N F L Y V S N T E K - L L L R I P V D S T D - K P G - - E P E I F V E - - - - - - Q T N I D D F A F D V - E G N L Y G A T - H I Y - - - - - - - - - - - - N S V V R I A P - D R - - S T T I I A Q A - - - E Q G V I G S T A V A F G Q T E G D C T A I Y V V T N G G F L P P P T - - - - - - - G V V P A N V V R L E - V G K P G Y P L G - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - M I P V I E P L F T K V T E - - - - - D I P G A E G P V F D K - N G D F Y I V A P E V E V N G K P A G E I L R I D L K T G K K T V I C K P E V N G Y G - - - G I P A G C Q C D R D - A - N Q L F V A D M R - - - - - L G L L V V Q T D G - - - - - T - F E E I A K K D S E G R R M Q G C N D C A F D Y E G N L W I T A P A G E V A P A D Y T R S M - - Q E K F G S I Y C F T T D G - Q M I Q V D T - - A F Q - - - - - - - F P N G I A V R H M N D G R P Y Q L I V A E T P T K K L W S Y D I K G - P A K I E - - N K K V W G H I P G T - H E G G A D G M D F D E - D N N L L V A N W - G S - - - - - - - - - - - - S H I E V F G P - D G G Q P K M R I R C P F - - - - - - E K P S N L H F K P Q - - - T K T I F V T E H - - E N - - - - - - - - - - - - - - - N A V W K F E - W Q R N G K K Q Y C E T L K F G I F
- - - - - - - - - - - - - - - - D Q S S F Q T R F N V H R E V T P V E L P N C N L V G I D - - - - - - N G S E D L E I L P - N G L A F I S S G L - - - - - - - S G K I L L M D L N E P A V S E L E I I - G N T L D I S S F N P H G I S T F I D D N T V Y L L V V N H P G - - S S S T V E V F K F Q - - - - - E S L L H L T I R - - - - - H L L P S V N D I V A V - G P H F Y A T N D H Y F I D P Y L K S W E M H L G L A W S F V T Y Y S P - - N D V R V V A - - - G F D - - - - - - - F A N G I N I S P - - - - D G K Y V Y I A E L L A H K I H V Y E K H A N W - T L T P - - - - L V L S F - - - - - D T L V D N I S V D P V T G D L W V G C H P N G M R I F F Y D A N P P G S E V L R I Q D I L - S P V T V V Y A E N G T - - - V L Q G S T V A A V Y K - - - - - - G L L I G T V F - - - - - - - - - - - - - - - - - - H K A L Y C D L - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G P V V E K I - - - A E L G K Y T V G E G P H W D H E T Q T L Y F V D T V E - - - - - - - K T F H K Y V P S Q K K Y T F - C K V D - - - - - - - - K L V S F I I P L A G - S P G R F V V S L E - - - - - - R E I A I L T W D G V S A A P T S I E A I V N V E P H I K - N N R L N D G K A D P L G N L W T G T M A I D A G L P I - - - - - - - G P V T G S L Y H L G A D K - K V K M H E S - - N I A - - - - - - - I A N G L A W S N - - - - D L K K M Y Y I D S G K R R V D E Y D Y D A S T L S I - S - N Q R P L F T F E K H E V P G Y P D G Q T I D E - E G N L W V A V F - Q G - - - - - - - - - - - - Q R I I K I S T Q Q P E V L L D T V K I P - - - - - - D P Q V T S V A F G G P - - N L D E L Y V T S A G L Q L D D S S F D - - K S L V N - - G H V Y R V T G L G V K G F A G V K V K L - - - - -

 

 

 

 

 

Member Chain UniProtKB GO term
d2ghsa1 A Q7D0W3 GO:0004341
d2ghsa1 A Q7D0W3 GO:0005509
d2ghsa1 A Q7D0W3 GO:0019853
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in