Superfamily : 63737 [ Zn aminopeptidase N-terminal domain ]
Class : All beta proteins
Fold : Zn aminopeptidase N-terminal domain
# of Members : 5
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1z1wa1  (   1 )                      meVekYdLtLdFdiq-----krtFnGtEtItA
d3u9wa1  (1003 )    ivdtcSlAspas-----vCrTkhLhLrCsVdft-----rrTLtgtAaLtV
d4fkea1  (  63 )    qskpwnr-----yrLpttLlPdsYnVtLrPyltpnadglyiFkgkSiVrF
d4qmea1  (   2 )    s-----tvhylkdyqtPaYhilktdlhFdin-e-----p-qtvvkSrltv
d6q4ra1  (  45 )    tpfpwnk-----irLPeyViPvhYdLlIhAnLt-----tltFwGtTkVeI
                                      bbbbbbbbbbbb          bbbbbbbbbb

                             60        70        80        90        100 
d1z1wa1  (  28 )    da-----gdIvLdAvgLqIn----wMkVngr--------dtaftyd--gq
d3u9wa1  (1043 )    qSqednlrsLvLDTkdLtIe----kVvIng------qevkyalgerqsyk
d4fkea1  ( 108 )    lCqep-tdvIIIHSkkLnYtTqghmVvLrGvgdsqvpeidrTelve--lT
d4qmea1  (  41 )    ePqrvge-plvldGs-akll----sVking------aaAdyvle------
d6q4ra1  (  85 )    tAsqp-tstIILHShhLqIs----rAtLrkl---seepL-qvlehp--rq
                    bb      bbbbb    bbb    bbbb            bbbb      

                             110       120       130       140       150 
d1z1wa1  (  59 )    -tVrApGds------qpQkIeIsFagkVsd-slsGIyyagr---------
d3u9wa1  (1083 )    GspMeIsLpiaLsknqeivIeIsFeTsp---kSsALqWlt---peqtsgk
d4fkea1  ( 155 )    -eYLVVhLkgsLqpghmYeMeSeFqgeLad-dlaGFyrseymegn----v
d4qmea1  (  73 )    getltia--gvps--erFtveveteilPaenkslGlyasg----------
d6q4ra1  ( 129 )    -eQIALlApepLlvglpYtVVIhYagnLse-tfhGFykstyrtke---ge
                      bbbbb          bbbbbbbbb         bbbb           

                             160       170       180       190       200 
d1z1wa1  (  92 )    engmItThFeatdArrMFPCvDhpaykAvFaItVvIdkd--ydAiSnmpp
d3u9wa1  (1127 )    ehpyLfSqCqaihCRAILPcQDTpsVkLtYtAeVsVpke--LvAlMsAir
d4fkea1  ( 199 )    kkvlAtTqMqstdArkSFPCFDepamkAtFnItLiHpnn--ltAlSnmpp
d4qmea1  ( 110 )    g--nlftqCepegFrkitFYiDrpdv-SkFtttivAdkkrypvllSngnk
d6q4ra1  ( 174 )    lrilAsTqFeptaArmAFPCFDepafkAsFsIkIrrepr--HlAiSnmpl
                       bbbb      333            bbbbbbbb      bbbb   b

                             210       220       230    
d1z1wa1  ( 140 )    krievs-----erkvVeFqdTprmSTylLyVGIGkf
d3u9wa1  (1175 )    dg-etpDpedpsrkiykFiqkvpipCylIaLvVGa 
d4fkea1  ( 247 )    kgsstplaedpnwsvTeFetTpvmSTylLaYiVSef
d4qmea1  ( 158 )    id-ggefs--dgrhwvkwedpfsKpSylFalvAg  
d6q4ra1  ( 222 )    vk-svtvae--glieDhFdvTvkmSTylVaFiISdf
                    bb bbb      bbbbbb       333  bbbb
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Tricorn protease interacting factor F3 N-terminal domainZn aminopeptidase N-terminal domainThermoplasma acidophilum [TaxId: 2303]view
Leukotriene A4 hydrolase N-terminal domainZn aminopeptidase N-terminal domainHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesPig (Sus scrofa) [TaxId: 9823]view
Aminopeptidase N (APN) N-terminal domainZn aminopeptidase N-terminal domainNeisseria meningitidis [TaxId: 122586]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230
- - - - - - - - - - - - - - - - - - M E V E K Y D L T L D F D I Q - - - - - K R T F N G T E T I T A D A - - - - - G D I V L D A V G L Q I N - - - - W M K V N G R - - - - - - - - D T A F T Y D - - G Q - T V R A P G D S - - - - - - Q P Q K I E I S F A G K V S D - S L S G I Y Y A G R - - - - - - - - - E N G M I T T H F E A T D A R R M F P C V D H P A Y K A V F A I T V V I D K D - - Y D A I S N M P P K R I E V S - - - - - E R K V V E F Q D T P R M S T Y L L Y V G I G K F
I V D T C S L A S P A S - - - - - V C R T K H L H L R C S V D F T - - - - - R R T L T G T A A L T V Q S Q E D N L R S L V L D T K D L T I E - - - - K V V I N G - - - - - - Q E V K Y A L G E R Q S Y K G S P M E I S L P I A L S K N Q E I V I E I S F E T S P - - - K S S A L Q W L T - - - P E Q T S G K E H P Y L F S Q C Q A I H C R A I L P C Q D T P S V K L T Y T A E V S V P K E - - L V A L M S A I R D G - E T P D P E D P S R K I Y K F I Q K V P I P C Y L I A L V V G A -
Q S K P W N R - - - - - Y R L P T T L L P D S Y N V T L R P Y L T P N A D G L Y I F K G K S I V R F L C Q E P - T D V I I I H S K K L N Y T T Q G H M V V L R G V G D S Q V P E I D R T E L V E - - L T - E Y L V V H L K G S L Q P G H M Y E M E S E F Q G E L A D - D L A G F Y R S E Y M E G N - - - - V K K V L A T T Q M Q S T D A R K S F P C F D E P A M K A T F N I T L I H P N N - - L T A L S N M P P K G S S T P L A E D P N W S V T E F E T T P V M S T Y L L A Y I V S E F
S - - - - - T V H Y L K D Y Q T P A Y H I L K T D L H F D I N - E - - - - - P - Q T V V K S R L T V E P Q R V G E - P L V L D G S - A K L L - - - - S V K I N G - - - - - - A A A D Y V L E - - - - - - G E T L T I A - - G V P S - - E R F T V E V E T E I L P A E N K S L G L Y A S G - - - - - - - - - - G - - N L F T Q C E P E G F R K I T F Y I D R P D V - S K F T T T I V A D K K R Y P V L L S N G N K I D - G G E F S - - D G R H W V K W E D P F S K P S Y L F A L V A G - -
T P F P W N K - - - - - I R L P E Y V I P V H Y D L L I H A N L T - - - - - T L T F W G T T K V E I T A S Q P - T S T I I L H S H H L Q I S - - - - R A T L R K L - - - S E E P L - Q V L E H P - - R Q - E Q I A L L A P E P L L V G L P Y T V V I H Y A G N L S E - T F H G F Y K S T Y R T K E - - - G E L R I L A S T Q F E P T A A R M A F P C F D E P A F K A S F S I K I R R E P R - - H L A I S N M P L V K - S V T V A E - - G L I E D H F D V T V K M S T Y L V A F I I S D F

 

 

 

 

 

Member Chain UniProtKB GO term
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in