Superfamily : 63712 [ Nicotinic receptor ligand binding domain-like ]
Class : All beta proteins
Fold : Nicotinic receptor ligand binding domain-like
# of Members : 6
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d2xysa-  (   1 )      qanlmrLksdlfn---rspmypGPtk--ddpltVTLgFtLqdIvkvds
d4afha-  (   1 )    snglmakrLrrelLntYeqlgksglPflddigkVdVkFgLSLqllksieq
d4uxua-  (   3 )      gkyaqkLfndLfe---dYsnalrPvedtdkvLnVtLqItLsqIkdMde
d6dw1a-  (  12 )       tvftrildrlld---gYdnrlrPgl--g-vTeVkTdIfVtsFGpVsd
d6dw1b-  (   8 )      nsyvketvdrLlk---gY-irlRpfg--gppvdVGMrIdVasIdmvsv
d7ndva-  (  20 )       ldradIlynIrq---tSrpdviPtqr-drpVaVsVSLkFinIleVne
                         aaaaaaaaa                   bbbbbbbbbbbbbbbb 

                             60        70        80        90        100 
d2xysa-  (  44 )    s----tnEVDLvYyEqQrWkL---nslmwdpneygnitdFrTs---aadI
d4afha-  (  51 )    rgmgfnSiGTFkAiVkLsWvDtiL---rwdpeppfdfqkIeIs---PdeI
d4uxua-  (  48 )    r----nqiLtAyLwirQiWhD---ayLtWdrdqydgldsirip---SdlV
d6dw1a-  (  56 )    -----dmEYtIdVfFrQsWkD----rLkFk----gpmtvlrln-lmaskI
d6dw1b-  (  54 )    -----nmdYtLtMyFqQsWkDk---rLsYs----giplnltldnrvAdqL
d7ndva-  (  63 )    i----tneVDVvFwqqTtWsDrtL---awnss--hSpdqVsVp---issL
                           bbbbbbbbbbbbb                   bbb        

                             110       120       130       140       150 
d2xysa-  (  84 )    wtPdItAysstr-pvqvls----pqiAvVthdGsVmfipaqrLSFmçdPt
d4afha-  (  95 )    WtPdIkLfnSvdldMtldr----ttqAiVfsnGtVlWiPpAvLkVlÇvsq
d4uxua-  (  88 )    WrPdIvlynkaddesspv-----ntnVvLrydGlItwdapaitkSsÇvvd
d6dw1a-  (  94 )    WtPdTffhnGkk--svahnmtmpnklLrItedGtLlYtmrltVrAeÇpMh
d6dw1b-  (  92 )    WvPdTyflndkk--sfvhgvtvknrmIrLhpdGtVlyglritTtAaÇmm-
d7ndva-  ( 101 )    WvPdLaAynais-kpevlt----pqlArVvsdGeVlymPsIrqrFsçdVs
                        bbb                  bbbb    bbbb  bbbbbbb    

                             160       170       180       190       200 
d2xysa-  ( 129 )    gvdse-eGvtÇaVkFGSwvySGfeIdLkTdt--dqVdlssyyasSkyeIl
d4afha-  ( 141 )    d-----dvdsÇhFqFgSwvysvdeVDIhfmddkaeVlldfyq-ds-leil
d4uxua-  ( 134 )    vtyfPfdNQqÇnLtFGSwtynGnqVdIfnal--dsGdlsdfiedveWeVh
d6dw1a-  ( 142 )    led--pDahaÇpLkFGSyaytraeVvYeWtrparSVvvadgsrLnqYdll
d6dw1b-  ( 140 )    lrryplDeqnÇtLeIESygyttddIeFywnggegAVtgvnkIeLpqFsiv
d7ndva-  ( 146 )    gVdte-sGAtÇrIkIGSwthhsreIsVdpts--d--dseyFsqysrFeIl
                            bbbbbbbbb       bbbb                    bb

                             210       220       230 
d2xysa-  ( 176 )    sAtQtrqvqhysccpepyiDVnLvVkFrer 
d4afha-  ( 184 )    ensAqrqevvypccesayVeMkYlLALrse 
d4uxua-  ( 182 )    gMpAvknvisygccsepyPdVtFtLlLkrrs
d6dw1a-  ( 194 )    gqtvdsgivqsst--geyvVMtThFhLkrk 
d6dw1b-  ( 190 )    dykMvskkveftt--gayprLsLsfrLkrn 
d7ndva-  ( 194 )    dVtqkknsvtysccpeayeDVeVsLnFrkkg
                    bbbbbbbbb        bbbbbbbbbbb
 

 

Domain IDNameFamilySourceDomainSTRING-DB
automated matchesautomated matchesCalifornia sea hare (Aplysia californica) [TaxId: 6500]view
automated matchesautomated matchesCapitella teleta [TaxId: 283909]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesNorway rat (Rattus norvegicus) [TaxId: 10116]view
automated matchesautomated matchesNorway rat (Rattus norvegicus) [TaxId: 10116]view
automated matchesNicotinic receptor ligand binding domain-likeGreat pond snail (Lymnaea stagnalis) [TaxId: 6523]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230
- - Q A N L M R L K S D L F N - - - R S P M Y P G P T K - - D D P L T V T L G F T L Q D I V K V D S S - - - - T N E V D L V Y Y E Q Q R W K L - - - N S L M W D P N E Y G N I T D F R T S - - - A A D I W T P D I T A Y S S T R - P V Q V L S - - - - P Q I A V V T H D G S V M F I P A Q R L S F M C D P T G V D S E - E G V T C A V K F G S W V Y S G F E I D L K T D T - - D Q V D L S S Y Y A S S K Y E I L S A T Q T R Q V Q H Y S C C P E P Y I D V N L V V K F R E R -
S N G L M A K R L R R E L L N T Y E Q L G K S G L P F L D D I G K V D V K F G L S L Q L L K S I E Q R G M G F N S I G T F K A I V K L S W V D T I L - - - R W D P E P P F D F Q K I E I S - - - P D E I W T P D I K L F N S V D L D M T L D R - - - - T T Q A I V F S N G T V L W I P P A V L K V L C V S Q D - - - - - D V D S C H F Q F G S W V Y S V D E V D I H F M D D K A E V L L D F Y Q - D S - L E I L E N S A Q R Q E V V Y P C C E S A Y V E M K Y L L A L R S E -
- - G K Y A Q K L F N D L F E - - - D Y S N A L R P V E D T D K V L N V T L Q I T L S Q I K D M D E R - - - - N Q I L T A Y L W I R Q I W H D - - - A Y L T W D R D Q Y D G L D S I R I P - - - S D L V W R P D I V L Y N K A D D E S S P V - - - - - N T N V V L R Y D G L I T W D A P A I T K S S C V V D V T Y F P F D N Q Q C N L T F G S W T Y N G N Q V D I F N A L - - D S G D L S D F I E D V E W E V H G M P A V K N V I S Y G C C S E P Y P D V T F T L L L K R R S
- - - T V F T R I L D R L L D - - - G Y D N R L R P G L - - G - V T E V K T D I F V T S F G P V S D - - - - - D M E Y T I D V F F R Q S W K D - - - - R L K F K - - - - G P M T V L R L N - L M A S K I W T P D T F F H N G K K - - S V A H N M T M P N K L L R I T E D G T L L Y T M R L T V R A E C P M H L E D - - P D A H A C P L K F G S Y A Y T R A E V V Y E W T R P A R S V V V A D G S R L N Q Y D L L G Q T V D S G I V Q S S T - - G E Y V V M T T H F H L K R K -
- - N S Y V K E T V D R L L K - - - G Y - I R L R P F G - - G P P V D V G M R I D V A S I D M V S V - - - - - N M D Y T L T M Y F Q Q S W K D K - - - R L S Y S - - - - G I P L N L T L D N R V A D Q L W V P D T Y F L N D K K - - S F V H G V T V K N R M I R L H P D G T V L Y G L R I T T T A A C M M - L R R Y P L D E Q N C T L E I E S Y G Y T T D D I E F Y W N G G E G A V T G V N K I E L P Q F S I V D Y K M V S K K V E F T T - - G A Y P R L S L S F R L K R N -
- - - L D R A D I L Y N I R Q - - - T S R P D V I P T Q R - D R P V A V S V S L K F I N I L E V N E I - - - - T N E V D V V F W Q Q T T W S D R T L - - - A W N S S - - H S P D Q V S V P - - - I S S L W V P D L A A Y N A I S - K P E V L T - - - - P Q L A R V V S D G E V L Y M P S I R Q R F S C D V S G V D T E - S G A T C R I K I G S W T H H S R E I S V D P T S - - D - - D S E Y F S Q Y S R F E I L D V T Q K K N S V T Y S C C P E A Y E D V E V S L N F R K K G

 

 

 

 

 

Member Chain UniProtKB GO term
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in