Superfamily : 57262 [ Leech antihemostatic proteins ]
Class : Small proteins
Fold : Knottins (small inhibitors, toxins, lectins)
# of Members : 5
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1bx7a-  (   3 )    gntÇgge-tçsa---Aqvçlk---gçnevhÇrirÇkyglkkdengÇey
d1deca-  (   1 )    ap----rlpqÇqgddqekÇlÇn-kdppg-qÇrfprgdadpe     
d1e0fi-  (   1 )    irfgmgkvpÇpdgeVgytÇDÇg-eklygqn----------dgqÇsg
d1skza1  (   7 )      gÇeea-gÇpe---gsniitdrçtÇsgvrçrvhÇphgfqrsryGçe-
d2pw8i1  (   3 )           ytdÇtesgQNlÇlÇegsngqgnkÇilgsdgeknqçvtgeGt
                                              b                       

                             60       
d1bx7a-  (  47 )    pçsçak---------a  
d1deca-                               
d1e0fi-  (  40 )    dpkpssefeefeideeek
d1skza1  (  50 )    fçkçrl---------epm
d2pw8i1  (  46 )    pkpqsgdfeeipeelq  
                                      

 

 

Domain IDNameFamilySourceDomainSTRING-DB
HirustasinHuristasin-likeMedicinal leech (Hirudo medicinalis) [TaxId: 6421]view
DecorsinHirudin-likeNorth american leech (Macrobdella decora) [TaxId: 6405]view
HaemadinHirudin-likeIndian leech (Haemadipsa sylvestris) [TaxId: 13555]view
Factor Xa inhibitor antistasinHuristasin-likeMexican leech (Haementeria officinalis) [TaxId: 6410]view
automated matchesHirudin-likeMedicinal leech (Hirudo medicinalis) [TaxId: 6421]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60
G N T C G G E - T C S A - - - A Q V C L K - - - G C V C N E V H C R I R C K Y G L K K D E N G C E Y P C S C A K - - - - - - - - - A - -
A P - - - - R L P Q C Q G D D Q E K C L C N - K D E C P P G - Q C R F P R G D A D P Y C E - - - - - - - - - - - - - - - - - - - - - - -
I R F G M G K V P C P D G E V G Y T C D C G - E K I C L Y G Q S C N - - - - - - - - - - D G Q C S G D P K P S S E F E E F E I D E E E K
- - G C E E A - G C P E - - - G S A C N I I T D R C T C S G V R C R V H C P H G F Q R S R Y G C E - F C K C R L - - - - - - - - - E P M
- - - - - - - Y T D C T E S G Q N L C L C E G S N V C G Q G N K C I L G S D G E K N Q C V T G E G T P K P Q S G D F E E I P E E L Q - -

 

 

 

 

 

Member Chain UniProtKB GO term
d1bx7a_ A P80302 GO:0004857
d1bx7a_ A P80302 GO:0004867
d1bx7a_ A P80302 GO:0005576
d1bx7a_ A P80302 GO:0008201
d1bx7a_ A P80302 GO:0010466
d1bx7a_ A P80302 GO:0050819
d1deca_ A P17350 GO:0004857
d1deca_ A P17350 GO:0005576
d1deca_ A P17350 GO:0007155
d1e0fi_ I P00734 GO:0004857
d1e0fi_ I P00734 GO:0004867
d1e0fi_ I P00734 GO:0010466
d1e0fi_ I Q25163 GO:0004857
d1e0fi_ I Q25163 GO:0004867
d1e0fi_ I Q25163 GO:0010466
d1skza1 A P15358 GO:0004857
d1skza1 A P15358 GO:0004867
d1skza1 A P15358 GO:0005576
d1skza1 A P15358 GO:0008201
d1skza1 A P15358 GO:0010466
d1skza1 A P15358 GO:0050819