Superfamily : 56762 [ HydB/Nqo4-like ]
Class : Multi-domain proteins (alpha and beta)
Fold : HydB/Nqo4-like
# of Members : 6
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d4u9hl-  (  20 )    s-ysgpivvdpvtrieghlrieveve--ngkvknAySSStl-frGlEiil
d5aa5c-  (  19 )      klvemnwdpItrIvgsLGIyTkIdfenrrVaeCySTSsi-frgYsifM
d5odqf-  (   2 )        vklsvepVtrVeGhGkIsVsFdd-sgnldkVrFhVve-vrgFekfL
d6qgra-  (   2 )       tkvVEIspTtrLeghSKLTLkVnd-qgiVerGDWLSitpvrgIeklA
d6z8mb-  (  13 )    atgrttiaidpvtrieghlkAevvve--ngkvvdArlsGgm-yrGFEtil
d6zk94-  (  45 )      snltlnfgp-----gvlrlvMeLsge--mVrkCdphigl-lhgteklI
                        bbbbb          bbbbbb      bbbbbbb       aaaa 

                             60        70        80        90        100 
d4u9hl-  (  66 )    kgrdPrdAqhftqrtCgvÇtYtHAlAStRCvDnAvgvhipknAtYiRnlv
d5aa5c-  (  66 )    kgkdPrdSHfiTSrICgiÇGDNHATCSVYAQNMAYgvkPPpIADWIINLG
d5odqf-  (  46 )    egryVedAPiyTPrIÇgiÇQVAHHLASAkAVdnVfgVkIpetAelLRnLM
d6qgra-  (  48 )    igktmeqVPkiASrVCgiCPIAHTLASTeAMEASIgCeiptdAklLRiIL
d6z8mb-  (  60 )    rgrdPrdASqivqri-gvçPtAHStASvlAldeAFgAkvpnnGRitRnli
d6zk94-  (  92 )    eyktYlqALpyFDrLDyVSMMCNEQAYSlAVEklLniqPPprAqWIRVLF
                           aaaa        aaaaaaaaaaaaaaaa     aaaaaaaaaa

                             110       120       130       140       150 
d4u9hl-  ( 116 )    lGAqYlhDHivHFYhlHAlDFvdvtaAlkAdpakAAkvAssisprkttaa
d5aa5c-  ( 116 )    EAAEYMFDHNiFQDNlVgvDFCeqmVr----------------------e
d5odqf-  (  96 )    HQGATVHSHAlHFYmlAAPDLmfPttd-----------------------
d6qgra-  (  98 )    HAANRIHSHAlHN-ilILpdFYipgte-----------------------
d6z8mb-  ( 110 )    FGAnYlqSHilHFYHlSAqDFvqGp-----dtapfvprfpkSdlrls---
d6zk94-  ( 142 )    GEITRLLNHImAV-TtHAldIg----------------------------
                    aaaaaaaaaaaaa a                                   

                             160       170       180       190       200 
d4u9hl-  ( 166 )    dlkavqdklktfvesgqlgpftnayFlggHpaYyldpetnliAt----Ah
d5aa5c-  ( 144 )    TNpgVwekAkt-----aeAphaaeHg------yrTIAdIMtaLnpftgeF
d5odqf-  ( 123 )    -----------------------------dvlkrnlmgIakehp----ei
d6qgra-  ( 124 )    -----------------------------k--kFnLfaneqpAr----sV
d6z8mb-  ( 152 )    ------------------------------------kelnkaGv----dq
d6zk94-  ( 163 )    ------------------------------------------am----tP
                                                                    aa

                             210       220       230       240       250 
d4u9hl-  ( 212 )    yleAlrlqvkAarAMavFGaknphtqFtvvGGvtcydAltpqriaeFeal
d5aa5c-  ( 183 )    yreTllVSryTreMFclMEgrhvhPstLyPGGVgt--vptiqlFtdYitr
d5odqf-  ( 140 )    IkdAieLrkaGqnVVrvVGgraihPvTAvvGGQsk--sLkeeerdeLlkl
d6qgra-  ( 139 )    marIvrIreIAqtIAaiAGgeaihPsNPrIGGMyh--nvsprakqkMadl
d6z8mb-  ( 162 )    yieAlevrriCheMvalFGgrMphvqGqvvGGAte--iPtkeklveYaar
d6zk94-  ( 167 )    ffwMfeErekMfeFYerVSgarmhAaYVrPGGVhq--dLplgLmddIyeF
                    aaaaaaaaaaaaaaaaaaa        bb  bb       aaaaaaaaaa

                             260       270       280       290       300 
d4u9hl-  ( 262 )    wketkaFvdevYipDllvvAaaYk-------------dWtqyGgt-dnFi
d5aa5c-  ( 231 )    LmkYVefMK-kVVPLHdDLFdFFyeAlp---------gYeeVGrRrilLG
d5odqf-  ( 188 )    SertIeLSe-kSIevGkklLenIkde-----------dLldIGyfesaHM
d6qgra-  ( 187 )    AkeClvlVh-eQmefMldVIrnMqnrefVevggkqIpLpkkLGyhnqgvM
d6z8mb-  ( 210 )    FkkvrdFveqkYvpvvYtiGSkYk-------------dMfkvGqgfkAAl
d6zk94-  ( 215 )    sknFslrId-eLeemLtn-nriWrn------------rTvdiGvVt----
                    aaaaaaaaa  aaaaaaaaaaa                            

                             310       320       330       340       350 
d4u9hl-  ( 298 )    tFGEFPkdeyd----------lnsRfFkPGvvfkrdfknikpFd----km
d5aa5c-  ( 271 )    CWGSFQdPnvCdYnYrtMtkWGrgMfVTPGVVVdg---ellttdLvdINl
d5odqf-  ( 226 )    GMVn-----nGvHdLYdg---------kLrVV-nsegkveyeFdpseYmn
d6qgra-  ( 236 )    ATap-----myGsssldd---------nptWd-ftr---wketr---pwd
d6z8mb-  ( 247 )    CvGAFpldnsg-----------kkhlFmpgvYAkg---kdmpFd----ps
d6zk94-  ( 247 )    -----------------aedAlny--------------------------
                                                                      

                             360       370       380       390       400 
d4u9hl-  ( 334 )    qieEhvrHSWYe---------------g-aeArhPwkGqtqpkytdlhgd
d5aa5c-  ( 318 )    nIrILlgSSfYqdWdheetsVknDplgnaVdrkHPWNQtTlprpqkrnfg
d5odqf-  ( 261 )    yIaegvk-------------------------------------------
d6qgra-  ( 265 )    wYMgevtIdledpsypigGTtkvgt---------------------kAnP
d6z8mb-  ( 279 )    kikEyvkySwFa---------------eettglnYkegktipapdka---
d6zk94-  ( 254 )    --------------------------------------------------
                                                                      

                             410       420       430       440       450 
d4u9hl-  ( 368 )    drYSwMkAPRYm------gepMEtG--PlAqvliAysqghpkvkavtdav
d5aa5c-  ( 368 )    gnYTwVmSPRWlDkrtgdhlALDTGGGPIARLWATAlag-----lVdigy
d5odqf-  ( 268 )    -pySyLkFPyLkdkgeed-GiYRVN--TLSRLNVSdkMaTplAqkyYdeF
d6qgra-  ( 294 )    qmeScTgVPTydg------qPvEVG--PrARlatfk--------------
d6z8mb-  ( 311 )    gAYSfvkAPRYd------glSlEvG--PlARMWvnnpelSpvGkkllkdl
d6zk94-  ( 254 )    ---------------------gFsG--VMLRGSgi--qwDLRktqpydVY
                           bbbb                aaaaaaa                

                             460       470       480       490       500 
d4u9hl-  ( 410 )    ---la----------klgvg------pealfStlGRtAARGiEtaviAey
d5aa5c-  ( 413 )    IkStghSVkIyLprtalkpeaefeWkipmwSNAIERDrARTyFQAYSAAA
d5odqf-  ( 314 )    ---vkef----------------gkp---CHhPMLFHyARLIELLsSAEm
d6qgra-  ( 322 )    -----------------------nfd---ekGTfAQHiARQmeYpdCCyt
d6z8mb-  ( 353 )    ---Fg-----isAkkFrdlg------eeaAFSlMGRHvARAEEtyyMlga
d6zk94-  ( 279 )    d-----qVeFdvpigs-------------rGDCydRYlCRVeEMrqSirI
                                                    aaaaaaaaaaaaaaaaaa

                             510       520       530       540       550 
d4u9hl-  ( 441 )    vgvMlqeYkdniakgdnvica----------------------------p
d5aa5c-  ( 463 )    AlyFAeqAlaelhagrtrtft----------------------------d
d5odqf-  ( 342 )    VkelLendkIvge----dira----------------------------e
d6qgra-  ( 346 )    IlncLdnLntsg-----kvlad---------------------------h
d6z8mb-  ( 389 )    iegWlkeikag-----edtvv----------------------------m
d6zk94-  ( 311 )    IsqClnkMpp------geikvddakvSppkraemktsmeslihhfklyte
                    aaaaaa                                            

                             560       570       580       590       600 
d4u9hl-  ( 463 )    wempkqaeGvGfvnAPRGGlSHWiried-gkignFqlvvPStWtlGPrCd
d5aa5c-  ( 485 )    fkvpdeaiGCGFHEAVRGVLSHHLVIrd-gkIanYHPYPPTPWNASPrDi
d5odqf-  ( 360 )    peevvg-dGVGCVEAPRGTLIHhFkTdddGiItdTnLVVATVQN------
d6qgra-  ( 364 )    ipqgdgsmGWAANEAPRGSNIHLArVkd-gkVrwYdMLVPTTWN------
d6z8mb-  ( 406 )    pavpasaeGtGftEAPRGSllHYvkvkd-skidnYqivSASlWnCnPrDd
d6zk94-  ( 355 )    gyqVppgatyTaIEAPKGeFGVyLvSdgssrPyrCkIkAPGfaHLa----
                          bbbbbbbbb  bbbbbbbbb     bbbbbbb  aaaa      

                             610       620       630       640       
d4u9hl-  ( 512 )    knklSPvEaSligtpva---dak-----rPvEilRtvHSFDPCiaÇGvH
d5aa5c-  ( 534 )    ygtpGPYEdAVqnTpIfEengpekF---kGIDImRAVRSFDPCLpÇGVh
d5odqf-  ( 403 )    ---NPAMDiGVrkVAekyIkapedAtpqvlNyMeMLIRAYDPÇLsÇATH
d6qgra-  ( 407 )    ---FPTCSrALt--------------gAPWqIAeMVVRAYDPCVsCATh
d6z8mb-  ( 455 )    mgqrGAvEeAligipvd---diq-----nPvnvaRlirAFDPl-sçAvH
d6zk94-  ( 401 )    -----GLdkMSk--------------ghmlaDVvAIigTQdIvFgEVDr
                         aaaaa                     aaaaaaa     aaaaa
 

 

Domain IDNameFamilySourceDomainSTRING-DB
automated matchesNickel-iron hydrogenase, large subunitDesulfovibrio vulgaris [TaxId: 883]view
automated matchesautomated matchesCupriavidus necator [TaxId: 381666]view
automated matchesautomated matchesMethanothermococcus thermolithotrophicus [TaxId: 523845]view
automated matchesautomated matchesMethanosarcina barkeri [TaxId: 1434108]view
automated matchesNickel-iron hydrogenase, large subunitDesulfovibrio vulgaris [TaxId: 882]view
automated matchesautomated matchesSheep (Ovis aries) [TaxId: 9940]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640
S - Y S G P I V V D P V T R I E G H L R I E V E V E - - N G K V K N A Y S S S T L - F R G L E I I L K G R D P R D A Q H F T Q R T C G V C T Y T H A L A S T R C V D N A V G V H I P K N A T Y I R N L V L G A Q Y L H D H I V H F Y H L H A L D F V D V T A A L K A D P A K A A K V A S S I S P R K T T A A D L K A V Q D K L K T F V E S G Q L G P F T N A Y F L G G H P A Y Y L D P E T N L I A T - - - - A H Y L E A L R L Q V K A A R A M A V F G A K N P H T Q F T V V G G V T C Y D A L T P Q R I A E F E A L W K E T K A F V D E V Y I P D L L V V A A A Y K - - - - - - - - - - - - - D W T Q Y G G T - D N F I T F G E F P K D E Y D - - - - - - - - - - L N S R F F K P G V V F K R D F K N I K P F D - - - - K M Q I E E H V R H S W Y E - - - - - - - - - - - - - - - G - A E A R H P W K G Q T Q P K Y T D L H G D D R Y S W M K A P R Y M - - - - - - G E P M E T G - - P L A Q V L I A Y S Q G H P K V K A V T D A V - - - L A - - - - - - - - - - K L G V G - - - - - - P E A L F S T L G R T A A R G I E T A V I A E Y V G V M L Q E Y K D N I A K G D N V I C A - - - - - - - - - - - - - - - - - - - - - - - - - - - - P W E M P K Q A E G V G F V N A P R G G L S H W I R I E D - G K I G N F Q L V V P S T W T L G P R C D K N K L S P V E A S L I G T P V A - - - D A K - - - - - R P V E I L R T V H S F D P C I A C G V H
- - K L V E M N W D P I T R I V G S L G I Y T K I D F E N R R V A E C Y S T S S I - F R G Y S I F M K G K D P R D S H F I T S R I C G I C G D N H A T C S V Y A Q N M A Y G V K P P P I A D W I I N L G E A A E Y M F D H N I F Q D N L V G V D F C E Q M V R - - - - - - - - - - - - - - - - - - - - - - E T N P G V W E K A K T - - - - - A E A P H A A E H G - - - - - - Y R T I A D I M T A L N P F T G E F Y R E T L L V S R Y T R E M F C L M E G R H V H P S T L Y P G G V G T - - V P T I Q L F T D Y I T R L M K Y V E F M K - K V V P L H D D L F D F F Y E A L P - - - - - - - - - G Y E E V G R R R I L L G C W G S F Q D P N V C D Y N Y R T M T K W G R G M F V T P G V V V D G - - - E L L T T D L V D I N L N I R I L L G S S F Y Q D W D H E E T S V K N D P L G N A V D R K H P W N Q T T L P R P Q K R N F G G N Y T W V M S P R W L D K R T G D H L A L D T G G G P I A R L W A T A L A G - - - - - L V D I G Y I K S T G H S V K I Y L P R T A L K P E A E F E W K I P M W S N A I E R D R A R T Y F Q A Y S A A A A L Y F A E Q A L A E L H A G R T R T F T - - - - - - - - - - - - - - - - - - - - - - - - - - - - D F K V P D E A I G C G F H E A V R G V L S H H L V I R D - G K I A N Y H P Y P P T P W N A S P R D I Y G T P G P Y E D A V Q N T P I F E E N G P E K F - - - K G I D I M R A V R S F D P C L P C G V H
- - - - V K L S V E P V T R V E G H G K I S V S F D D - S G N L D K V R F H V V E - V R G F E K F L E G R Y V E D A P I Y T P R I C G I C Q V A H H L A S A K A V D N V F G V K I P E T A E L L R N L M H Q G A T V H S H A L H F Y M L A A P D L M F P T T D - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - D V L K R N L M G I A K E H P - - - - E I I K D A I E L R K A G Q N V V R V V G G R A I H P V T A V V G G Q S K - - S L K E E E R D E L L K L S E R T I E L S E - K S I E V G K K L L E N I K D E - - - - - - - - - - - D L L D I G Y F E S A H M G M V N - - - - - N G V H D L Y D G - - - - - - - - - K L R V V - N S E G K V E Y E F D P S E Y M N Y I A E G V K - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - P Y S Y L K F P Y L K D K G E E D - G I Y R V N - - T L S R L N V S D K M A T P L A Q K Y Y D E F - - - V K E F - - - - - - - - - - - - - - - - G K P - - - C H H P M L F H Y A R L I E L L S S A E M V K E L L E N D K I V G E - - - - D I R A - - - - - - - - - - - - - - - - - - - - - - - - - - - - E P E E V V G - D G V G C V E A P R G T L I H H F K T D D D G I I T D T N L V V A T V Q N - - - - - - - - - N P A M D I G V R K V A E K Y I K A P E D A T P Q V L N Y M E M L I R A Y D P C L S C A T H
- - - T K V V E I S P T T R L E G H S K L T L K V N D - Q G I V E R G D W L S I T P V R G I E K L A I G K T M E Q V P K I A S R V C G I C P I A H T L A S T E A M E A S I G C E I P T D A K L L R I I L H A A N R I H S H A L H N - I L I L P D F Y I P G T E - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - K - - K F N L F A N E Q P A R - - - - S V M A R I V R I R E I A Q T I A A I A G G E A I H P S N P R I G G M Y H - - N V S P R A K Q K M A D L A K E C L V L V H - E Q M E F M L D V I R N M Q N R E F V E V G G K Q I P L P K K L G Y H N Q G V M A T A P - - - - - M Y G S S S L D D - - - - - - - - - N P T W D - F T R - - - W K E T R - - - P W D W Y M G E V T I D L E D P S Y P I G G T T K V G T - - - - - - - - - - - - - - - - - - - - - K A N P Q M E S C T G V P T Y D G - - - - - - Q P V E V G - - P R A R L A T F K - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - N F D - - - E K G T F A Q H I A R Q M E Y P D C C Y T I L N C L D N L N T S G - - - - - K V L A D - - - - - - - - - - - - - - - - - - - - - - - - - - - H I P Q G D G S M G W A A N E A P R G S N I H L A R V K D - G K V R W Y D M L V P T T W N - - - - - - - - - F P T C S R A L T - - - - - - - - - - - - - - G A P W Q I A E M V V R A Y D P C V S C A T H
A T G R T T I A I D P V T R I E G H L K A E V V V E - - N G K V V D A R L S G G M - Y R G F E T I L R G R D P R D A S Q I V Q R I - G V C P T A H S T A S V L A L D E A F G A K V P N N G R I T R N L I F G A N Y L Q S H I L H F Y H L S A Q D F V Q G P - - - - - D T A P F V P R F P K S D L R L S - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - K E L N K A G V - - - - D Q Y I E A L E V R R I C H E M V A L F G G R M P H V Q G Q V V G G A T E - - I P T K E K L V E Y A A R F K K V R D F V E Q K Y V P V V Y T I G S K Y K - - - - - - - - - - - - - D M F K V G Q G F K A A L C V G A F P L D N S G - - - - - - - - - - - K K H L F M P G V Y A K G - - - K D M P F D - - - - P S K I K E Y V K Y S W F A - - - - - - - - - - - - - - - E E T T G L N Y K E G K T I P A P D K A - - - G A Y S F V K A P R Y D - - - - - - G L S L E V G - - P L A R M W V N N P E L S P V G K K L L K D L - - - F G - - - - - I S A K K F R D L G - - - - - - E E A A F S L M G R H V A R A E E T Y Y M L G A I E G W L K E I K A G - - - - - E D T V V - - - - - - - - - - - - - - - - - - - - - - - - - - - - M P A V P A S A E G T G F T E A P R G S L L H Y V K V K D - S K I D N Y Q I V S A S L W N C N P R D D M G Q R G A V E E A L I G I P V D - - - D I Q - - - - - N P V N V A R L I R A F D P L - S C A V H
- - S N L T L N F G P - - - - - G V L R L V M E L S G E - - M V R K C D P H I G L - L H G T E K L I E Y K T Y L Q A L P Y F D R L D Y V S M M C N E Q A Y S L A V E K L L N I Q P P P R A Q W I R V L F G E I T R L L N H I M A V - T T H A L D I G - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - A M - - - - T P F F W M F E E R E K M F E F Y E R V S G A R M H A A Y V R P G G V H Q - - D L P L G L M D D I Y E F S K N F S L R I D - E L E E M L T N - N R I W R N - - - - - - - - - - - - R T V D I G V V T - - - - - - - - - - - - - - - - - - - - - A E D A L N Y - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G F S G - - V M L R G S G I - - Q W D L R K T Q P Y D V Y D - - - - - Q V E F D V P I G S - - - - - - - - - - - - - R G D C Y D R Y L C R V E E M R Q S I R I I S Q C L N K M P P - - - - - - G E I K V D D A K V S P P K R A E M K T S M E S L I H H F K L Y T E G Y Q V P P G A T Y T A I E A P K G E F G V Y L V S D G S S R P Y R C K I K A P G F A H L A - - - - - - - - - G L D K M S K - - - - - - - - - - - - - - G H M L A D V V A I I G T Q D I V F G E V D R

 

 

 

 

 

Member Chain UniProtKB GO term
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in