Superfamily : 56747 [ Prim-pol domain ]
Class : Alpha and beta proteins (a+b)
Fold : Prim-pol domain
# of Members : 4
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1ro2a-  (  40 )                                                      
d1v33a-  (   1 )         mllreVtreeRknFYtneWkvkdIpdfIvktlelREFGFDhsgeg
d1zt2a1  (   3 )    tftlhqgqtnlIksfFrnyYlnae--leLp----kdmelREFALqpfgsd
d2atza1  (   5 )                                 elklIkidtshyFekkpglge
                                                             bbb      

                             60        70        80        90        100 
d1ro2a-  (  40 )                                                      
d1v33a-  (  46 )    ---------psdrknqytdirdLedyIra-tAPyAVySSVAlYekPq---
d1zt2a1  (  47 )    ---------tyvrhlsfssseeLrdyLvnrnLPlhLfYSSArYqlpsarn
d2atza1  (  26 )    rvdyagrcfynkfqrvnaLtssliqkHlkr--eieIAHnLIlr-------
                                        aaaaaaaa       bbbb           

                             110       120       130       140       150 
d1ro2a-  (  40 )                                                      
d1v33a-  (  83 )    --emegwlGTELVFdIdAkdLpLrrcehe---------------------
d1zt2a1  (  88 )    meeK-awmGSDLLFdIdadhlÇklrsirFCpvcGnavvsekcerdnveTl
d2atza1  (  68 )    -------------------------------------------ndkVeNI
                                                                      

                             160       170       180       190       200 
d1ro2a-  (  40 )                sserIryAkwMleh----gfnIIPIdpeskkPvlk---
d1v33a-  ( 110 )    -pgtVcpiCLnDAkeIVrdTViILreElgFndIhIIYsG-rGYhIRVld-
d1zt2a1  ( 137 )    eYveMtseÇIkrgleqTrnLveILeddfgl-kPkVYFsGNrgFhVqVdçy
d2atza1  (  75 )    VFdYngr----nperFyhkAqllLree-gfnFTAYntktpghLhLYVhkg
                                aaaaaaaaaaaaaa       bbbb     bbbbb   

                             210       220       230       240       250 
d1ro2a-  (  71 )    -------------ewqkYShemPsd-------------------eekqrF
d1v33a-  ( 157 )    ewAlkldsksRerilsfVSASeiedveeFrklLlnkrgwFvlnhg-yPrA
d1zt2a1  ( 186 )    gnçAlldsdeRkeiAeyVmGi------gvpgyp-----------------
d2atza1  ( 121 )    ----hTelgeGerlVktLSkLaq-------------glpkeWkvf-Psne
                           aaaaaaaaaaa                                

                             260       270       280       290       300 
d1ro2a-  (  89 )    lkmIeegynYAIPGGQkgMVIMdFeskekLkaWIgesaLeelÇrkTLÇTn
d1v33a-  ( 206 )    FRlRFG-------YFI-----lRIklphLinagIrksiAksIlkske---
d1zt2a1  ( 213 )    --------------------------------------------------
d2atza1  ( 154 )    wPkefN----ILaLpy---evfakerg-----------------------
                                                                      

                             310       320       330       340       350 
d1ro2a-  ( 139 )    tVhgGIHIYVlSndiPphkInpLFeen-----------------------
d1v33a-  ( 241 )    eIyeeFVrkailaAFpq-----gVgieslAkLFalSTrfSksYFdgrVTv
d1zt2a1  ( 213 )    ----------------------ggsenapgWvGRknrginGVtIdeqVTi
d2atza1  ( 174 )    --------------------------------------------------
                                                                      

                             360       370       380       390       400 
d1ro2a-  ( 166 )    ----gkgIIdLqsynsyVlGLgSçvnHlhçttd-------------kÇpw
d1v33a-  ( 286 )    dlkriLrLPsTLHSkvGLiAkyVgtnerdVm---rfnPFk----------
d1zt2a1  ( 241 )    dvkrlIrIPnSLhGkSGLiVkrV-pnlddfeFnetLSpftgyTiFlPyit
d2atza1  ( 174 )    -----------------------------------------sswak    
                          b                                           

                             410       420       430       440       450 
d1ro2a-  ( 199 )    keqnyttçytlynelkeIskVdLkslLrfLaekGkrlgItlsktAkewle
d1v33a-  ( 323 )    --------hAVPkfRke----eVkveykkflesl---gt           
d1zt2a1  ( 290 )    ieteVLgsiikLnrgipikikSSiGIYLhlrnLG---eVkayv       
d2atza1                                                               
                                          aaaaaaaa                    

                     
d1ro2a-  ( 249 )    g
d1v33a-              
d1zt2a1              
d2atza1
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Bifunctional DNA primase/polymerase N-terminal domainBifunctional DNA primase/polymerase N-terminal domainSulfolobus islandicus [TaxId: 43080]view
DNA primasePriA-likePyrococcus horikoshii [TaxId: 53953]view
DNA primase small subunit PriAPriA-likeSulfolobus solfataricus [TaxId: 2287]view
Hypothetical protein HP0184HP0184-likeHelicobacter pylori [TaxId: 210]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - S S E R I R Y A K W M L E H - - - - G F N I I P I D P E S K K P V L K - - - - - - - - - - - - - - - - E W Q K Y S H E M P S D - - - - - - - - - - - - - - - - - - - E E K Q R F L K M I E E G Y N Y A I P G G Q K G M V I M D F E S K E K L K A W I G E S A L E E L C R K T L C T N T V H G G I H I Y V L S N D I P P H K I N P L F E E N - - - - - - - - - - - - - - - - - - - - - - - - - - - G K G I I D L Q S Y N S Y V L G L G S C V N H L H C T T D - - - - - - - - - - - - - K C P W K E Q N Y T T C Y T L Y N E L K E I S K V D L K S L L R F L A E K G K R L G I T L S K T A K E W L E G
- - - - - M L L R E V T R E E R K N F Y T N E W K V K D I P D F I V K T L E L R E F G F D H S G E G - - - - - - - - - P S D R K N Q Y T D I R D L E D Y I R A - T A P Y A V Y S S V A L Y E K P Q - - - - - E M E G W L G T E L V F D I D A K D L P L R R C E H E - - - - - - - - - - - - - - - - - - - - - - P G T V C P I C L N D A K E I V R D T V I I L R E E L G F N D I H I I Y S G - R G Y H I R V L D - E W A L K L D S K S R E R I L S F V S A S E I E D V E E F R K L L L N K R G W F V L N H G - Y P R A F R L R F G - - - - - - - Y F I - - - - - L R I K L P H L I N A G I R K S I A K S I L K S K E - - - E I Y E E F V R K A I L A A F P Q - - - - - G V G I E S L A K L F A L S T R F S K S Y F D G R V T V D L K R I L R L P S T L H S K V G L I A K Y V G T N E R D V M - - - R F N P F K - - - - - - - - - - - - - - - - - - H A V P K F R K E - - - - E V K V E Y K K F L E S L - - - G T - - - - - - - - - - - -
T F T L H Q G Q T N L I K S F F R N Y Y L N A E - - L E L P - - - - K D M E L R E F A L Q P F G S D - - - - - - - - - T Y V R H L S F S S S E E L R D Y L V N R N L P L H L F Y S S A R Y Q L P S A R N M E E K - A W M G S D L L F D I D A D H L C K L R S I R F C P V C G N A V V S E K C E R D N V E T L E Y V E M T S E C I K R G L E Q T R N L V E I L E D D F G L - K P K V Y F S G N R G F H V Q V D C Y G N C A L L D S D E R K E I A E Y V M G I - - - - - - G V P G Y P - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G G S E N A P G W V G R K N R G I N G V T I D E Q V T I D V K R L I R I P N S L H G K S G L I V K R V - P N L D D F E F N E T L S P F T G Y T I F L P Y I T I E T E V L G S I I K L N R G I P I K I K S S I G I Y L H L R N L G - - - E V K A Y V - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - E L K L I K I D T S H Y F E K K P G L G E R V D Y A G R C F Y N K F Q R V N A L T S S L I Q K H L K R - - E I E I A H N L I L R - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - N D K V E N I V F D Y N G R - - - - N P E R F Y H K A Q L L L R E E - G F N F T A Y N T K T P G H L H L Y V H K G - - - - H T E L G E G E R L V K T L S K L A Q - - - - - - - - - - - - - G L P K E W K V F - P S N E W P K E F N - - - - I L A L P Y - - - E V F A K E R G - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - S S W A K - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

 

 

 

 

 

Member Chain UniProtKB GO term
d1v33a_ A O57934 GO:0000428
d1v33a_ A O57934 GO:0003896
d1v33a_ A O57934 GO:0006259
d1v33a_ A O57934 GO:0006260
d1v33a_ A O57934 GO:0006269
d1v33a_ A O57934 GO:0016779
d1v33a_ A O57934 GO:0046872
d1v33a_ A O57934 GO:1990077
d1zt2a1 A Q97Z83 GO:0000428
d1zt2a1 A Q97Z83 GO:0003896
d1zt2a1 A Q97Z83 GO:0005515
d1zt2a1 A Q97Z83 GO:0006259
d1zt2a1 A Q97Z83 GO:0006260
d1zt2a1 A Q97Z83 GO:0006269
d1zt2a1 A Q97Z83 GO:0016779
d1zt2a1 A Q97Z83 GO:0046872
d1zt2a1 A Q97Z83 GO:1990077
d1zt2a1 A Q9UWW1 GO:0000428
d1zt2a1 A Q9UWW1 GO:0003896
d1zt2a1 A Q9UWW1 GO:0005515
d1zt2a1 A Q9UWW1 GO:0006259
d1zt2a1 A Q9UWW1 GO:0006260
d1zt2a1 A Q9UWW1 GO:0006269
d1zt2a1 A Q9UWW1 GO:0016779
d1zt2a1 A Q9UWW1 GO:0046872
d1zt2a1 A Q9UWW1 GO:1990077
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in