BASE   PART 1   PART 2   PART 3   PART 4  
Superfamily : 56601 [ beta-lactamase/transpeptidase-like ]
Class : Multi-domain proteins (alpha and beta)
Fold : beta-lactamase/transpeptidase-like
# of Members : 8
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1ci9a-  (  15 )                                                      
d1ei5a3  (   3 )                                                      
d1yqsa-  (   3 )                                                      
d2d83a-  (   2 )                                                      
d2dcfa1  (   5 )    stgqhpaRypgAaagePtldswqepphnrwAfahlgeMvpsaavsrrpgh
d2ffya-  (   4 )                                                      
d6kbya1  (   1 )                                                      
d6njka-  (  26 )                                                      
                                                                      

                             60        70        80        90        100 
d1ci9a-  (  15 )         aaslaarLdavFdqAlrerrLVGAVaIVArhgeilYrraqglAdr
d1ei5a3  (   3 )          kfdtsaLeafVrhIpqnykGPGGVVAVVkdgevvLqhawgfAdl
d1yqsa-  (   3 )       l-paPddtgLqaVLhtAlsqg-ApGAMVrVddng-tihqlsegvAdr
d2d83a-  (   2 )          sdlnnaIqgiLddHvarg-VvGVSLALclpgeetslyqsgyAdk
d2dcfa1  (  59 )    alar-lgaIaaqlp-dLeqrLeqTyTDAFLVLr--gtevvAeYYra----
d2ffya-  (   4 )        apqqindivhrtitplieqqkipGMAvAviyqgkp-yyftwgyadi
d6kbya1  (   1 )     anideskikdtVddlIqpLmqknnIpGMSVAVTvngkn-yiynyglaak
d6njka-  (  26 )      sAtseqivdiAdasFapvieqyriPGlvvGitWqgqh-SfyatgvAar
                            aaaaaaaaaaaaaa     bbbbbbbb  bb bbbbbbbbb 

                             110       120       130       140       150 
d1ci9a-  (  60 )    eagrpMredTLFrLAsVTKPIVALAVLrLvargeLaldApVtrwlpeFrP
d1ei5a3  (  47 )    rtrtpMtldtrMpICsVSKQFTCAVLLdaV----gePelLddaLeayLd-
d1yqsa-  (  47 )    atgraItTtDrFRVGsVTKSFSAVVLLqLvdegkLdLdasVntylpglLp
d2d83a-  (  45 )    fnkmpMtgdhLFRIAsCTKSFIATGLHLLvqdgtVdLdepItrWfpdlpk
d2dcfa1  ( 101 )    ----gfapddrhlLmaVSKSLCGTVVGALvdegrIdpaqpVteyVpeLa-
d2ffya-  (  49 )    akkqpvtqqtlFElGsvSKtFtGvlGGDAiArgeiklsDpttkywpelt-
d6kbya1  (  49 )    qpqqpVtenTLFEVGsLSKTFAATLASyAqvsgkLsldqsVShyVpeLr-
d6njka-  (  73 )    kgnvaAtpdtiFElGsiSKiFtAtlAAlaedrg-ldldapvsdsipqle-
                       bb      bb 333aaaaaaaaaaaaaa                   

                             160       170       180       190       200 
d1ci9a-  ( 110 )    rladgseplVtIhhLLTHtSGLGY-wlleGagsvydrlgISdGidlr-df
d1ei5a3  (  92 )    ---kFederPaVrdLCnNQSGLrdYwalsvlc----------gadpegvf
d1yqsa-  (  97 )    dd------rItVrqVMSHrSGLyd-YtndmfaqtvpgFes---Vrnk-vf
d2d83a-  (  95 )    Aa------qMpVrILLnHrSgLPd-FetsM--pMis---------dk-sW
d2dcfa1  ( 146 )    ---gSvYdgpsVlqVLdMqIsIdYnedyvdpaSevqtHdrSAgwrtrrhg
d2ffya-  (  98 )    ---akqWngitllhlAtYtAGGlplqvpd------------------evk
d6kbya1  (  98 )    ---gssFdhVsVlnVGTHTS-gLqlfmpe------------------dIk
d6njka-  ( 122 )    ---gaaFGairlvDlstHvtGGlplqvpg------------------evg
                               aaaaa                                  

                             210       220       230       240       250 
d1ci9a-  ( 158 )    dLdeNLrrLasA-pLsfaPgsgwqySL-ALDVLGAVVeratgqpLaaAVd
d1ei5a3  ( 129 )    lpaqAqslLrrlktThfepgshysyCnGNFRILAdLIeahtgrtLvdiLs
d1yqsa-  ( 136 )    syqdLItlSlkh-gvtnapgaaysySnTNFVVAGmLIekltghsVatEYq
d2d83a-  ( 126 )    taqeIVdfSfrh-gvqkePwhgMeySnTGYVLAGmIIahetgkpYSdHLr
d2dcfa1  ( 193 )    dpadTYeFLttL-rgdgstg-eFqyCsANTDVLAWIVErvTglrYveALs
d2ffya-  ( 127 )    sssdllrfYqnw-qpawapgtqRlyAnSSiGlFGalAvkpSglsFeqAMq
d6kbya1  ( 126 )    nttqLmayLkaw-kpadaAgthRvySnIGTGLLGmIAAkslgvsYedAIe
d6njka-  ( 151 )    nvaelirwlesw-qppqp--gtRsYSnvSiGllGhitaqt-g-sFaqaAq
                     aaaaaaaaa                aaaaaaaaaaaaaa    aaaaaa

                             260       270       280       290       300 
d1ci9a-  ( 206 )    alVAqplgMrdCgFvSa---eperFAvPYhdgq-pePvrMrdgievpLpe
d1ei5a3  ( 179 )    -eiFapAgM-rAeLisd-talfd-eCtGYegdtv----------------
d1yqsa-  ( 185 )    nrIFtplnLtdTfYvhpdtvIpgthAnGYLtpde---------ag-ga--
d2d83a-  ( 175 )    srIFaplgMkdTwVGthetfpierEArGYMhaaaddenpqWdvsgagdpv
d2dcfa1  ( 241 )    tyLwakLdAdr--------------datItvDt-----------------
d2ffya-  ( 176 )    trvFqplklnhtwinvp-paeeknyAwGyre-------------------
d6kbya1  ( 175 )    ktLLpqLgMhhSyLkVp-adqmenyAwGYnk-------------------
d6njka-  ( 198 )    dvlFpa-glgstyvdvp-ddA-dryAfGYdr-------------------
                    a                           b                     

                             310       320       330       340       350 
d1ci9a-  ( 252 )    ghgaavrFApsrvfepgAYpSGGAgMyGSAdDVlrALeAIranp-----g
d1ei5a3  ( 211 )    ---rgflpAtn---r--iqwmGDAGICASLndMIaWEqfIdatr--d---
d1yqsa-  ( 223 )    -----lvdSTe---QtVSwAQSAgAVISSTqDLDtFFsALMsg------q
d2d83a-  ( 225 )    dg---VwdSTew--FplsGaNAAgDMVSTPrDIVkFLnALFdg------r
d2dcfa1  ( 260 )    ----------------tGFGFAngGVsCTArDLArVGrMMLdgGvApggr
d2ffya-  ( 206 )    -----gkavhv---spgaldaeAygvkStiedMArWvqsnlkpl--dine
d6kbya1  ( 205 )    ---k-depvhv---nmeilGnEAyGIKTTSsdLLrYVqANMgql--l---
d6njka-  ( 228 )    ---ktdapirv---npgvladeAygvkStArD-lrlldlElgrg--gan-
                           b                  bb aaaaaaaaaaaa         

                             360       370       380       390       400 
d1ci9a-  ( 297 )    FLpetlAdaArrdqA-g--vgaeTr--gpGWGFGYLSAVLdd---paaA-
d1ei5a3  ( 248 )    ---dglYrrLsgpqtfkd---------gvaApYGFGLnLhetg-------
d1yqsa-  ( 259 )    LMsaaqlaqMq-qwt-tvn---st------qGYGLGLrrrdL---s----
d2d83a-  ( 264 )    ILdqkrlwEMkdnik-pAffpgSnT-----vaNGHGLLlMrY---g----
d2dcfa1  ( 294 )    VVsedWVrrVlaGgsheaMtdkgftntfpdGSYTrQWwCTg-----neR-
d2ffya-  ( 246 )    ktlqqGiqlAqsRYWqtg-----------dMyqGlGWEMldWpvnpdsii
d6kbya1  ( 247 )    akMqqALtaTHtGyfkSg-----------eItQDLMWeQLpypVslpnLl
d6njka-  ( 269 )    paltaAlertrqGqAeta-----------yYtqD-iWeqYpwpvdvar-e
                       aaaaaaa                     bb    bbbb         

                             410       420       430       440       450 
d1ci9a-  ( 338 )    ---------------------gTpQhagTLqwgGvyG--HsWFVDralGl
d1ei5a3  ( 281 )    ------------------------gkrLTGHgGalrGWrCqRwhCaderL
d1yqsa-  ( 291 )    -----------------------çgisVyGHtGtVqGYYTYAFAskdGkR
d2d83a-  ( 301 )    ------------------------sseLkGHLGqIPGHTSIMGrDeetgA
d2dcfa1  ( 338 )    ---------------------g------NVSGiGihG--QNLWLDpltdS
d2ffya-  ( 285 )    ngSdAkialaarpvkaitpptpavraSWvHKtgatgGFGSYvAFiPekel
d6kbya1  ( 286 )    tGNdma--mtksvAtpivpplppqenvWINKtGstnGFGAYIAFVPakkM
d6njka-  ( 308 )    aGngydFilspqpAtrltpplppqrdvilnKtGatnGFGGYvAllpgqdl
                                              bbbbbbbb    bbbbbbb333 b

                             460       470       480     
d1ci9a-  ( 365 )    SvLLLTNTAYeGmsg---pLtialrdaVya       
d1ei5a3  ( 307 )    STIAMFNFeg---------gAseVAfkLMniALgv  
d1yqsa-  ( 318 )    SVTALANTsnn---vnVlnTMarTLesAFçGkp    
d2d83a-  ( 327 )    ALMLIQNSGAGdfeSfyLkGVnePVdrVLeaIknsrs
d2dcfa1  ( 359 )    VIVKLSsWpdpdt-ehwhrlQngILldVSrALdav  
d2ffya-  ( 335 )    GivMlAnknYp------npaRvdAAwqilnalq    
d6kbya1  ( 334 )    GIVMLANknYs------idqRVtvAykILssLegnk 
d6njka-  ( 358 )    GivvlAnRnYp------neARvrathalitdllatq 
                    bbbbbb           aaaaaaaaaaaaa
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Esterase EstBbeta-Lactamase/D-ala carboxypeptidaseBurkholderia gladioli [TaxId: 28095]view
D-aminopeptidase, N-terminal domainbeta-Lactamase/D-ala carboxypeptidaseOchrobactrum anthropi [TaxId: 529]view
automated matchesbeta-Lactamase/D-ala carboxypeptidaseStreptomyces sp. [TaxId: 31952]view
D-Amino acid amidase DaaAbeta-Lactamase/D-ala carboxypeptidaseOchrobactrum anthropi [TaxId: 529]view
6-aminohexanoate-dimer hydrolase NylCbeta-Lactamase/D-ala carboxypeptidaseFlavobacterium sp. [TaxId: 239]view
AMPC beta-Lactamase, class Cbeta-Lactamase/D-ala carboxypeptidaseEscherichia coli, cephalosporinase [TaxId: 562]view
automated matchesautomated matchesKlebsiella pneumoniae [TaxId: 573]view
automated matchesautomated matchesSulfitobacter sp. [TaxId: 52598]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - A A S L A A R L D A V F D Q A L R E R R L V G A V A I V A R H G E I L Y R R A Q G L A D R E A G R P M R E D T L F R L A S V T K P I V A L A V L R L V A R G E L A L D A P V T R W L P E F R P R L A D G S E P L V T I H H L L T H T S G L G Y - W L L E G A G S V Y D R L G I S D G I D L R - D F D L D E N L R R L A S A - P L S F A P G S G W Q Y S L - A L D V L G A V V E R A T G Q P L A A A V D A L V A Q P L G M R D C G F V S A - - - E P E R F A V P Y H D G Q - P E P V R M R D G I E V P L P E G H G A A V R F A P S R V F E P G A Y P S G G A G M Y G S A D D V L R A L E A I R A N P - - - - - G F L P E T L A D A A R R D Q A - G - - V G A E T R - - G P G W G F G Y L S A V L D D - - - P A A A - - - - - - - - - - - - - - - - - - - - - - G T P Q H A G T L Q W G G V Y G - - H S W F V D R A L G L S V L L L T N T A Y E G M S G - - - P L T I A L R D A V Y A - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - K F D T S A L E A F V R H I P Q N Y K G P G G V V A V V K D G E V V L Q H A W G F A D L R T R T P M T L D T R M P I C S V S K Q F T C A V L L D A V - - - - G E P E L L D D A L E A Y L D - - - - K F E D E R P A V R D L C N N Q S G L R D Y W A L S V L C - - - - - - - - - - G A D P E G V F L P A Q A Q S L L R R L K T T H F E P G S H Y S Y C N G N F R I L A D L I E A H T G R T L V D I L S - E I F A P A G M - R A E L I S D - T A L F D - E C T G Y E G D T V - - - - - - - - - - - - - - - - - - - R G F L P A T N - - - R - - I Q W M G D A G I C A S L N D M I A W E Q F I D A T R - - D - - - - - - D G L Y R R L S G P Q T F K D - - - - - - - - - G V A A P Y G F G L N L H E T G - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G K R L T G H G G A L R G W R C Q R W H C A D E R L S T I A M F N F E G - - - - - - - - - G A S E V A F K L M N I A L G V - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - L - P A P D D T G L Q A V L H T A L S Q G - A P G A M V R V D D N G - T I H Q L S E G V A D R A T G R A I T T T D R F R V G S V T K S F S A V V L L Q L V D E G K L D L D A S V N T Y L P G L L P D D - - - - - - R I T V R Q V M S H R S G L Y D - Y T N D M F A Q T V P G F E S - - - V R N K - V F S Y Q D L I T L S L K H - G V T N A P G A A Y S Y S N T N F V V A G M L I E K L T G H S V A T E Y Q N R I F T P L N L T D T F Y V H P D T V I P G T H A N G Y L T P D E - - - - - - - - - A G - G A - - - - - - - L V D S T E - - - Q T V S W A Q S A G A V I S S T Q D L D T F F S A L M S G - - - - - - Q L M S A A Q L A Q M Q - Q W T - T V N - - - S T - - - - - - Q G Y G L G L R R R D L - - - S - - - - - - - - - - - - - - - - - - - - - - - - - - - C G I S V Y G H T G T V Q G Y Y T Y A F A S K D G K R S V T A L A N T S N N - - - V N V L N T M A R T L E S A F C G K P - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - S D L N N A I Q G I L D D H V A R G - V V G V S L A L C L P G E E T S L Y Q S G Y A D K F N K M P M T G D H L F R I A S C T K S F I A T G L H L L V Q D G T V D L D E P I T R W F P D L P K A A - - - - - - Q M P V R I L L N H R S G L P D - F E T S M - - P M I S - - - - - - - - - D K - S W T A Q E I V D F S F R H - G V Q K E P W H G M E Y S N T G Y V L A G M I I A H E T G K P Y S D H L R S R I F A P L G M K D T W V G T H E T F P I E R E A R G Y M H A A A D D E N P Q W D V S G A G D P V D G - - - V W D S T E W - - F P L S G A N A A G D M V S T P R D I V K F L N A L F D G - - - - - - R I L D Q K R L W E M K D N I K - P A F F P G S N T - - - - - V A N G H G L L L M R Y - - - G - - - - - - - - - - - - - - - - - - - - - - - - - - - - S S E L K G H L G Q I P G H T S I M G R D E E T G A A L M L I Q N S G A G D F E S F Y L K G V N E P V D R V L E A I K N S R S
S T G Q H P A R Y P G A A A G E P T L D S W Q E P P H N R W A F A H L G E M V P S A A V S R R P G H A L A R - L G A I A A Q L P - D L E Q R L E Q T Y T D A F L V L R - - G T E V V A E Y Y R A - - - - - - - - G F A P D D R H L L M A V S K S L C G T V V G A L V D E G R I D P A Q P V T E Y V P E L A - - - - G S V Y D G P S V L Q V L D M Q I S I D Y N E D Y V D P A S E V Q T H D R S A G W R T R R H G D P A D T Y E F L T T L - R G D G S T G - E F Q Y C S A N T D V L A W I V E R V T G L R Y V E A L S T Y L W A K L D A D R - - - - - - - - - - - - - - D A T I T V D T - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - T G F G F A N G G V S C T A R D L A R V G R M M L D G G V A P G G R V V S E D W V R R V L A G G S H E A M T D K G F T N T F P D G S Y T R Q W W C T G - - - - - N E R - - - - - - - - - - - - - - - - - - - - - - G - - - - - - N V S G I G I H G - - Q N L W L D P L T D S V I V K L S S W P D P D T - E H W H R L Q N G I L L D V S R A L D A V - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - A P Q Q I N D I V H R T I T P L I E Q Q K I P G M A V A V I Y Q G K P - Y Y F T W G Y A D I A K K Q P V T Q Q T L F E L G S V S K T F T G V L G G D A I A R G E I K L S D P T T K Y W P E L T - - - - A K Q W N G I T L L H L A T Y T A G G L P L Q V P D - - - - - - - - - - - - - - - - - - E V K S S S D L L R F Y Q N W - Q P A W A P G T Q R L Y A N S S I G L F G A L A V K P S G L S F E Q A M Q T R V F Q P L K L N H T W I N V P - P A E E K N Y A W G Y R E - - - - - - - - - - - - - - - - - - - - - - - - G K A V H V - - - S P G A L D A E A Y G V K S T I E D M A R W V Q S N L K P L - - D I N E K T L Q Q G I Q L A Q S R Y W Q T G - - - - - - - - - - - D M Y Q G L G W E M L D W P V N P D S I I N G S D A K I A L A A R P V K A I T P P T P A V R A S W V H K T G A T G G F G S Y V A F I P E K E L G I V M L A N K N Y P - - - - - - N P A R V D A A W Q I L N A L Q - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - A N I D E S K I K D T V D D L I Q P L M Q K N N I P G M S V A V T V N G K N - Y I Y N Y G L A A K Q P Q Q P V T E N T L F E V G S L S K T F A A T L A S Y A Q V S G K L S L D Q S V S H Y V P E L R - - - - G S S F D H V S V L N V G T H T S - G L Q L F M P E - - - - - - - - - - - - - - - - - - D I K N T T Q L M A Y L K A W - K P A D A A G T H R V Y S N I G T G L L G M I A A K S L G V S Y E D A I E K T L L P Q L G M H H S Y L K V P - A D Q M E N Y A W G Y N K - - - - - - - - - - - - - - - - - - - - - - K - D E P V H V - - - N M E I L G N E A Y G I K T T S S D L L R Y V Q A N M G Q L - - L - - - A K M Q Q A L T A T H T G Y F K S G - - - - - - - - - - - E I T Q D L M W E Q L P Y P V S L P N L L T G N D M A - - M T K S V A T P I V P P L P P Q E N V W I N K T G S T N G F G A Y I A F V P A K K M G I V M L A N K N Y S - - - - - - I D Q R V T V A Y K I L S S L E G N K -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - S A T S E Q I V D I A D A S F A P V I E Q Y R I P G L V V G I T W Q G Q H - S F Y A T G V A A R K G N V A A T P D T I F E L G S I S K I F T A T L A A L A E D R G - L D L D A P V S D S I P Q L E - - - - G A A F G A I R L V D L S T H V T G G L P L Q V P G - - - - - - - - - - - - - - - - - - E V G N V A E L I R W L E S W - Q P P Q P - - G T R S Y S N V S I G L L G H I T A Q T - G - S F A Q A A Q D V L F P A - G L G S T Y V D V P - D D A - D R Y A F G Y D R - - - - - - - - - - - - - - - - - - - - - - K T D A P I R V - - - N P G V L A D E A Y G V K S T A R D - L R L L D L E L G R G - - G A N - P A L T A A L E R T R Q G Q A E T A - - - - - - - - - - - Y Y T Q D - I W E Q Y P W P V D V A R - E A G N G Y D F I L S P Q P A T R L T P P L P P Q R D V I L N K T G A T N G F G G Y V A L L P G Q D L G I V V L A N R N Y P - - - - - - N E A R V R A T H A L I T D L L A T Q -

 

 

 

 

 

Member Chain UniProtKB GO term
d1ci9a_ A Q9KX40 GO:0005737
d1ci9a_ A Q9KX40 GO:0016787
d1ci9a_ A Q9KX40 GO:0005737
d1ci9a_ A Q9KX40 GO:0016787
d1ci9a_ A Q9KX40 GO:0005737
d1ci9a_ A Q9KX40 GO:0016787
d1ei5a3 A Q9ZBA9 GO:0004177
d1ei5a3 A Q9ZBA9 GO:0006508
d1ei5a3 A Q9ZBA9 GO:0004177
d1ei5a3 A Q9ZBA9 GO:0006508
d1ei5a3 A Q9ZBA9 GO:0004177
d1ei5a3 A Q9ZBA9 GO:0006508
d1ei5a3 A Q9ZBA9 GO:0004177
d1ei5a3 A Q9ZBA9 GO:0006508
d1ei5a3 A Q9ZBA9 GO:0004177
d1ei5a3 A Q9ZBA9 GO:0006508
d2dcfa1 A P07062 GO:0016787
d2dcfa1 A P07062 GO:0019875
d2dcfa1 A P07062 GO:0019876
d2dcfa1 A P07062 GO:0016787
d2dcfa1 A P07062 GO:0019875
d2dcfa1 A P07062 GO:0019876
d2dcfa1 A P07062 GO:0016787
d2dcfa1 A P07062 GO:0019875
d2dcfa1 A P07062 GO:0019876
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in