Superfamily : 56322 [ ADC synthase ]
Class : Alpha and beta proteins (a+b)
Fold : ADC synthase
# of Members : 6
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1i7qa-  (   5 )    kpqLtllkvqAs-yrgd-pTtLFhqLCgar------paTLLlEsAeindk
d1k0ea-  (   3 )      tlsPavitll-wrqdAAefyFsrLS-hl------pwAMLlHSGyAdhp
d1qdla-  (  -1 )          amevhpisefaspfeVFkcIErdf------kVAGLlEsi-----
d2fn1a2  (   3 )                     ifwptIsgvLrq------aeeCYVYer------
d2g5fa1  (  15 )           sssipmpagvnpAdLAAELaavVt-esvdedYLLYEc------
d3bzna-  (   1 )                   mqslttaLenlLrhlsqeipatpgIrVidipFplk
                                      aaaaaaaaa           bbbbb       

                             60        70        80        90        100 
d1i7qa-  (  47 )    qnlqSLLVIdSALRItAlgh--tVsVqAltaNGpaLLplLdeaLppeVrn
d1k0ea-  (  43 )    ySrfDIVVAepiCtLtTfgk--eTvVses---------------------
d1qdla-  (  40 )    --rySvIAWStngylkIh-----------ddPvniLngylk---------
d2fn1a2  (  39 )    --pcwYLGkgcqArLhInadGtqAtFidda--------------------
d2g5fa1  (  52 )    --gqWVLAAGvqAmVeLDsd--elrvirdg--------------------
d3bzna-  (  36 )    d------------------------------afdALsWLasQqtyPQFYW
                        bbbb      bbb                                 

                             110       120       130       140       150 
d1i7qa-  (  95 )    qarpnGreLtFpaidavqdedarLrslSVFdALrtIltLVd-spa---de
d1k0ea-  (  70 )    ----ekrtttt---------------ddPLqVLqqVLdradirPthnedl
d1qdla-  (  68 )    ----------------------------------------dlkladIp-g
d2fn1a2  (  67 )    -----geqkWavd--------------sIadCArrFmahpqVk-------
d2g5fa1  (  78 )    -----vtrqqwsg--------------rPGaaLgeaVd-rLLl-------
d3bzna-  (  56 )    qqrngdeEAVVLgAitrFt---------sLdqAqrfLrqhp-------eh
                                                 aaaaaaaa             

                             160       170       180       190       200 
d1i7qa-  ( 141 )    reAVMLGGLFAydLVagfenLpa-lrqdqrCpdFCFYLAETLLVLdhqrg
d1k0ea-  ( 101 )    pFQGGALGLFGYDLGrrfesLpeiAeqdivLPdMAVGIYdWALIVDhqrh
d1qdla-  (  77 )    lFkGGMIGYISydAVrfwekIrdlkpaAedWPyAEFFtPdNiIIYDhneg
d2fn1a2  (  91 )    -gr-rVYGQVgFnFAAhargiafnag---eWPLLTLTVPreeliFe---g
d2g5fa1  ( 102 )    -etdqAFGWVAFEFGVhryglqrLap---hTpLArVFSPrtrImVs---e
d3bzna-  (  90 )    a-dLrIWGLNafdps-----------------qGnLLLPrLEWrrcg--g
                         bbbbb                       bbbbb  bbbbb     

                             210       220       230       240       250 
d1i7qa-  ( 190 )    sArLQASVFSeqaseaqrLqhrLeqLqaeLqppqpiphqklenMqlscnq
d1k0ea-  ( 151 )    tVsLLShn---------dvnarrawLes--qqfspqedftLts-dWqsnM
d1qdla-  ( 127 )    kVyvnAdls-------------------svggcgdigeFkvsfydes--l
d2fn1a2  ( 134 )    nvtvya-----------------------------------aplaVdtal
d2g5fa1  ( 148 )    ILfaGrhraIrllatgvr--------------------eVpqsrsvdvsd
d3bzna-  ( 120 )    kAtLRLTLfse--ssLqhdAiqAkefIatLvsikplpglhLtttreqhwp
                     bbbb                                             

                             260       270       280       290       300 
d1i7qa-  ( 241 )    sdeeYgavVseLqeaIrqgeIfQVVPSRrFsLpC---paplgPYqtLkdn
d1k0ea-  ( 189 )    treqYgekFrqVqeyLhsgdCyQVNLAQrFhAty--sGdeWqAFlqLNqa
d1qdla-  ( 156 )    nknsYeriVseSLeyIrsgyIfQVVLSRFyRYif--sgdpLrIYynLrri
d2fn1a2  ( 171 )    ngeaYkqqVarAvaeIrrgeYvKVIVSrAipLps--rIdMpaTl-yGrqa
d2g5fa1  ( 184 )    p-sgFrrrVavAvdeIaagrYhkViLSRcv-Vpf--aIdFplTYRlGrrh
d3bzna-  ( 168 )    dktgWtqlIelAtktiaegeLdKVVLARATdLhFaspVnaAAMMaaSrrl
                     aaaaaaaaaaaaaaaa     bbbbbbbbb         aaaaaaaa  

                             310       320       330       340       350 
d1i7qa-  ( 288 )    NpSPyMFFMqDd-dFtLFGASPEsALkYdagnrqIeIyPIaGTRprGrra
d1k0ea-  ( 237 )    nrAPfSAFLrLe-qgAILSLSPERFIlCd--nseIqTrPIkGtlpra---
d1qdla-  ( 204 )    npspyMFYLkFd-eKyLIGSSpeLLFrVq--dniVetypiagtrprGadq
d2fn1a2  ( 219 )    NtPvrSFMFrQe-greALGFSPElVMsVt--gnkVvtePLaGTrdrmgn-
d2g5fa1  ( 231 )    ntPvrSFLLqLg-girALGYSpelVTaVra-dgVViTePlAgtralgrg-
d3bzna-  ( 218 )    nlnCYHFYMAfdgenaFLGSSPERLWrRr--dkaLrTEALaGTvannp--
                        bbbbbb     bbbbbb  bbbbbb    bbbb  bbbbbb     

                             360       370       380       390       400 
d1i7qa-  ( 337 )    dgsldldlDsrieleMrtdhkElaEHlmLvdlArndLarICqagsryvad
d1k0ea-  ( 295 )    -----------------nsakdraENlmIVdlMrnDIgrvAvagsvkvpe
d1qdla-  ( 251 )    ------eedlkleleLmnsekdkaeHlmLVdlarnDLgkVCvpgtvkvpe
d2fn1a2  ( 265 )    -----pehn-akeaeLlhdskEvlEHilSVkeAiaeLeaVClpgsVvved
d2g5fa1  ( 278 )    -----paidrlarddLesnskeiveHaiSVrsSleeItdiAepgsaavid
d3bzna-  ( 264 )    ----ddkqAqqlGewLmaddkNqrENmlVveDIcqrLqadTq--tldvl-
                               aaaaaa  aaaaaaaaaaaaaaaaaa         bbbb

                             410       420       430       440       450 
d1i7qa-  ( 387 )    ltkVdrYsfVMHLVSrVVGtLradLdVLhAYqACMNMGTLSGapkvrAMq
d1k0ea-  ( 328 )    lfvvepfpaVhHLVStItAqLpeqlhASdLLraAFPGGSITGApkvrAMe
d1qdla-  ( 295 )    lmyVekyshvQhIVSkViGtLkkkynALnVLsatFPaGtVSGapkpmAMn
d2fn1a2  ( 310 )    lmsVrqrgsVQHLGSgVSGqLa-nkdaWdAFtvLFPsITASGipKnaALn
d2g5fa1  ( 323 )    fmtVrergsvQhLgStIrArldpssdrMaALeaLFPAVtASGipkaaGVe
d3bzna-  ( 307 )    ppqvlrlrkVQHLrrcIwTsLn-kadDviCLhqLQptAAVAGlprdlArq
                    bbbbbb   bbbbbbbbbbb      aaaaaaaa   333 bb aaaaaa

                             460       470       480       490       500 
d1i7qa-  ( 437 )    lIaalrstrRGSYGGRVgyFTavrnLdTCIVirsAYVedghRtVQaGAgV
d1k0ea-  ( 378 )    IIDeLEpqrRnAWCGSIgYLSFCgNMdTSITirTLTAIngqIfCsAGGGI
d1qdla-  ( 345 )    IIetLEeykRgPYAGAVgfISAdgnAeFaIAirTAFLNkelLRIHaGAgI
d2fn1a2  ( 360 )    aImqIektpReLYSGAILLLdd--tFDAALVlrSVFQDsqrcWIQaGAGI
d2g5fa1  ( 373 )    AIfrlD-cpRglYSGAVVmLsadggLdAALTlrAAYqvggrTwLrAGAgI
d3bzna-  ( 356 )    fiarhEpftRewYAGSAGYLSlq-qSEFCVSlrSAkIsgnvVrLYAGAGI
                    aaaaa          bbbbb     bbbbb   bbbbb  bbbbbbbbbb

                             510       520       530 
d1i7qa-  ( 487 )    VqdSiperEAdeTrnkAraVLrAIataHhAvf
d1k0ea-  ( 428 )    VadSqeeaeyqeTfdkVnrIlkqLek      
d1qdla-  ( 395 )    vydSnpeseyfeTehkLkaLktAIgvr     
d2fn1a2  ( 409 )    IaqStperEltETrekLaSIapyLm       
d2g5fa1  ( 423 )    ieeseperEFeeTc-kLstLtpyLVar     
d3bzna-  ( 405 )    VrgSdpeqEwqeIdnkaagLrtLLqm      
                         aaaaaaaaaaaa
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Anthranilate synthase aminodeoxyisochorismate synthase/lyase subunit, TrpEADC synthaseSerratia marcescens [TaxId: 615]view
P-aminobenzoate synthase component IADC synthaseEscherichia coli [TaxId: 562]view
Anthranilate synthase aminodeoxyisochorismate synthase/lyase subunit, TrpEADC synthaseSulfolobus solfataricus [TaxId: 2287]view
Salicylate synthetase Irp9ADC synthaseYersinia enterocolitica [TaxId: 630]view
Salicylate synthase MbtIADC synthaseMycobacterium tuberculosis [TaxId: 1773]view
automated matchesADC synthaseEscherichia coli [TaxId: 562]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
K P Q L T L L K V Q A S - Y R G D - P T T L F H Q L C G A R - - - - - - P A T L L L E S A E I N D K Q N L Q S L L V I D S A L R I T A L G H - - T V S V Q A L T A N G P A L L P L L D E A L P P E V R N Q A R P N G R E L T F P A I D A V Q D E D A R L R S L S V F D A L R T I L T L V D - S P A - - - D E R E A V M L G G L F A Y D L V A G F E N L P A - L R Q D Q R C P D F C F Y L A E T L L V L D H Q R G S A R L Q A S V F S E Q A S E A Q R L Q H R L E Q L Q A E L Q P P Q P I P H Q K L E N M Q L S C N Q S D E E Y G A V V S E L Q E A I R Q G E I F Q V V P S R R F S L P C - - - P A P L G P Y Q T L K D N N P S P Y M F F M Q D D - D F T L F G A S P E S A L K Y D A G N R Q I E I Y P I A G T R P R G R R A D G S L D L D L D S R I E L E M R T D H K E L A E H L M L V D L A R N D L A R I C Q A G S R Y V A D L T K V D R Y S F V M H L V S R V V G T L R A D L D V L H A Y Q A C M N M G T L S G A P K V R A M Q L I A A L R S T R R G S Y G G R V G Y F T A V R N L D T C I V I R S A Y V E D G H R T V Q A G A G V V Q D S I P E R E A D E T R N K A R A V L R A I A T A H H A V F
- - T L S P A V I T L L - W R Q D A A E F Y F S R L S - H L - - - - - - P W A M L L H S G Y A D H P Y S R F D I V V A E P I C T L T T F G K - - E T V V S E S - - - - - - - - - - - - - - - - - - - - - - - - - E K R T T T T - - - - - - - - - - - - - - - D D P L Q V L Q Q V L D R A D I R P T H N E D L P F Q G G A L G L F G Y D L G R R F E S L P E I A E Q D I V L P D M A V G I Y D W A L I V D H Q R H T V S L L S H N - - - - - - - - - D V N A R R A W L E S - - Q Q F S P Q E D F T L T S - D W Q S N M T R E Q Y G E K F R Q V Q E Y L H S G D C Y Q V N L A Q R F H A T Y - - S G D E W Q A F L Q L N Q A N R A P F S A F L R L E - Q G A I L S L S P E R F I L C D - - N S E I Q T R P I K G T L P R A - - - - - - - - - - - - - - - - - - - - N S A K D R A E N L M I V D L M R N D I G R V A V A G S V K V P E L F V V E P F P A V H H L V S T I T A Q L P E Q L H A S D L L R A A F P G G S I T G A P K V R A M E I I D E L E P Q R R N A W C G S I G Y L S F C G N M D T S I T I R T L T A I N G Q I F C S A G G G I V A D S Q E E A E Y Q E T F D K V N R I L K Q L E K - - - - - -
- - - - - - A M E V H P I S E F A S P F E V F K C I E R D F - - - - - - K V A G L L E S I - - - - - - - R Y S V I A W S T N G Y L K I H - - - - - - - - - - - D D P V N I L N G Y L K - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - D L K L A D I P - G L F K G G M I G Y I S Y D A V R F W E K I R D L K P A A E D W P Y A E F F T P D N I I I Y D H N E G K V Y V N A D L S - - - - - - - - - - - - - - - - - - - S V G G C G D I G E F K V S F Y D E S - - L N K N S Y E R I V S E S L E Y I R S G Y I F Q V V L S R F Y R Y I F - - S G D P L R I Y Y N L R R I N P S P Y M F Y L K F D - E K Y L I G S S P E L L F R V Q - - D N I V E T Y P I A G T R P R G A D Q - - - - - - E E D L K L E L E L M N S E K D K A E H L M L V D L A R N D L G K V C V P G T V K V P E L M Y V E K Y S H V Q H I V S K V I G T L K K K Y N A L N V L S A T F P A G T V S G A P K P M A M N I I E T L E E Y K R G P Y A G A V G F I S A D G N A E F A I A I R T A F L N K E L L R I H A G A G I V Y D S N P E S E Y F E T E H K L K A L K T A I G V R - - - - -
- - - - - - - - - - - - - - - - - I F W P T I S G V L R Q - - - - - - A E E C Y V Y E R - - - - - - - - P C W Y L G K G C Q A R L H I N A D G T Q A T F I D D A - - - - - - - - - - - - - - - - - - - - - - - - - G E Q K W A V D - - - - - - - - - - - - - - S I A D C A R R F M A H P Q V K - - - - - - - - G R - R V Y G Q V G F N F A A H A R G I A F N A G - - - E W P L L T L T V P R E E L I F E - - - G N V T V Y A - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - A P L A V D T A L N G E A Y K Q Q V A R A V A E I R R G E Y V K V I V S R A I P L P S - - R I D M P A T L - Y G R Q A N T P V R S F M F R Q E - G R E A L G F S P E L V M S V T - - G N K V V T E P L A G T R D R M G N - - - - - - P E H N - A K E A E L L H D S K E V L E H I L S V K E A I A E L E A V C L P G S V V V E D L M S V R Q R G S V Q H L G S G V S G Q L A - N K D A W D A F T V L F P S I T A S G I P K N A A L N A I M Q I E K T P R E L Y S G A I L L L D D - - T F D A A L V L R S V F Q D S Q R C W I Q A G A G I I A Q S T P E R E L T E T R E K L A S I A P Y L M - - - - - - -
- - - - - - - S S S I P M P A G V N P A D L A A E L A A V V T - E S V D E D Y L L Y E C - - - - - - - - G Q W V L A A G V Q A M V E L D S D - - E L R V I R D G - - - - - - - - - - - - - - - - - - - - - - - - - V T R Q Q W S G - - - - - - - - - - - - - - R P G A A L G E A V D - R L L L - - - - - - - - E T D Q A F G W V A F E F G V H R Y G L Q R L A P - - - H T P L A R V F S P R T R I M V S - - - E I L F A G R H R A I R L L A T G V R - - - - - - - - - - - - - - - - - - - - E V P Q S R S V D V S D P - S G F R R R V A V A V D E I A A G R Y H K V I L S R C V - V P F - - A I D F P L T Y R L G R R H N T P V R S F L L Q L G - G I R A L G Y S P E L V T A V R A - D G V V I T E P L A G T R A L G R G - - - - - - P A I D R L A R D D L E S N S K E I V E H A I S V R S S L E E I T D I A E P G S A A V I D F M T V R E R G S V Q H L G S T I R A R L D P S S D R M A A L E A L F P A V T A S G I P K A A G V E A I F R L D - C P R G L Y S G A V V M L S A D G G L D A A L T L R A A Y Q V G G R T W L R A G A G I I E E S E P E R E F E E T C - K L S T L T P Y L V A R - - - - -
- - - - - - - - - - - - - - - M Q S L T T A L E N L L R H L S Q E I P A T P G I R V I D I P F P L K D - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - A F D A L S W L A S Q Q T Y P Q F Y W Q Q R N G D E E A V V L G A I T R F T - - - - - - - - - S L D Q A Q R F L R Q H P - - - - - - - E H A - D L R I W G L N A F D P S - - - - - - - - - - - - - - - - - Q G N L L L P R L E W R R C G - - G K A T L R L T L F S E - - S S L Q H D A I Q A K E F I A T L V S I K P L P G L H L T T T R E Q H W P D K T G W T Q L I E L A T K T I A E G E L D K V V L A R A T D L H F A S P V N A A A M M A A S R R L N L N C Y H F Y M A F D G E N A F L G S S P E R L W R R R - - D K A L R T E A L A G T V A N N P - - - - - - D D K Q A Q Q L G E W L M A D D K N Q R E N M L V V E D I C Q R L Q A D T Q - - T L D V L - P P Q V L R L R K V Q H L R R C I W T S L N - K A D D V I C L H Q L Q P T A A V A G L P R D L A R Q F I A R H E P F T R E W Y A G S A G Y L S L Q - Q S E F C V S L R S A K I S G N V V R L Y A G A G I V R G S D P E Q E W Q E I D N K A A G L R T L L Q M - - - - - -

 

 

 

 

 

Member Chain UniProtKB GO term
d1i7qa_ A P00897 GO:0000162
d1i7qa_ A P00897 GO:0004049
d1i7qa_ A P00897 GO:0005515
d1i7qa_ A P00897 GO:0009058
d1i7qa_ A P00897 GO:0016829
d1i7qa_ A P00897 GO:0046872
d1i7qa_ A P00900 GO:0000162
d1i7qa_ A P00900 GO:0004049
d1i7qa_ A P00900 GO:0005515
d1i7qa_ A P00900 GO:0009058
d1i7qa_ A P00900 GO:0016829
d1i7qa_ A P00900 GO:0046872
d1i7qa_ A P00897 GO:0000162
d1i7qa_ A P00897 GO:0004049
d1i7qa_ A P00897 GO:0005515
d1i7qa_ A P00897 GO:0009058
d1i7qa_ A P00897 GO:0016829
d1i7qa_ A P00897 GO:0046872
d1i7qa_ A P00900 GO:0000162
d1i7qa_ A P00900 GO:0004049
d1i7qa_ A P00900 GO:0005515
d1i7qa_ A P00900 GO:0009058
d1i7qa_ A P00900 GO:0016829
d1i7qa_ A P00900 GO:0046872
d1i7qa_ A P00897 GO:0000162
d1i7qa_ A P00897 GO:0004049
d1i7qa_ A P00897 GO:0005515
d1i7qa_ A P00897 GO:0009058
d1i7qa_ A P00897 GO:0016829
d1i7qa_ A P00897 GO:0046872
d1i7qa_ A P00900 GO:0000162
d1i7qa_ A P00900 GO:0004049
d1i7qa_ A P00900 GO:0005515
d1i7qa_ A P00900 GO:0009058
d1i7qa_ A P00900 GO:0016829
d1i7qa_ A P00900 GO:0046872
d1k0ea_ A P05041 GO:0000162
d1k0ea_ A P05041 GO:0000287
d1k0ea_ A P05041 GO:0008153
d1k0ea_ A P05041 GO:0009058
d1k0ea_ A P05041 GO:0009356
d1k0ea_ A P05041 GO:0009396
d1k0ea_ A P05041 GO:0016740
d1k0ea_ A P05041 GO:0046654
d1k0ea_ A P05041 GO:0046656
d1k0ea_ A P05041 GO:0046820
d1k0ea_ A P05041 GO:0046982
d1k0ea_ A P05041 GO:0120284
d1qdla_ A Q06128 GO:0000162
d1qdla_ A Q06128 GO:0004049
d1qdla_ A Q06128 GO:0009058
d1qdla_ A Q06128 GO:0016829
d1qdla_ A Q06128 GO:0046872
d1qdla_ A Q06129 GO:0000162
d1qdla_ A Q06129 GO:0004049
d1qdla_ A Q06129 GO:0009058
d1qdla_ A Q06129 GO:0016829
d1qdla_ A Q06129 GO:0046872
d1qdla_ A Q06128 GO:0000162
d1qdla_ A Q06128 GO:0004049
d1qdla_ A Q06128 GO:0009058
d1qdla_ A Q06128 GO:0016829
d1qdla_ A Q06128 GO:0046872
d1qdla_ A Q06129 GO:0000162
d1qdla_ A Q06129 GO:0004049
d1qdla_ A Q06129 GO:0009058
d1qdla_ A Q06129 GO:0016829
d1qdla_ A Q06129 GO:0046872
d1qdla_ A Q06128 GO:0000162
d1qdla_ A Q06128 GO:0004049
d1qdla_ A Q06128 GO:0009058
d1qdla_ A Q06128 GO:0016829
d1qdla_ A Q06128 GO:0046872
d1qdla_ A Q06129 GO:0000162
d1qdla_ A Q06129 GO:0004049
d1qdla_ A Q06129 GO:0009058
d1qdla_ A Q06129 GO:0016829
d1qdla_ A Q06129 GO:0046872
d2g5fa1 A P9WFX1 GO:0000162
d2g5fa1 A P9WFX1 GO:0000287
d2g5fa1 A P9WFX1 GO:0004106
d2g5fa1 A P9WFX1 GO:0005886
d2g5fa1 A P9WFX1 GO:0008909
d2g5fa1 A P9WFX1 GO:0009058
d2g5fa1 A P9WFX1 GO:0009697
d2g5fa1 A P9WFX1 GO:0010106
d2g5fa1 A P9WFX1 GO:0016829
d2g5fa1 A P9WFX1 GO:0016833
d2g5fa1 A P9WFX1 GO:0016853
d2g5fa1 A P9WFX1 GO:0019540
d2g5fa1 A P9WFX1 GO:0043904
d2g5fa1 A P9WFX1 GO:0046872
d2g5fa1 A P9WFX1 GO:0052572
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in