Superfamily : 55464 [ Origin of replication-binding domain, RBD-like ]
Class : Alpha and beta proteins (a+b)
Fold : Origin of replication-binding domain, RBD-like
# of Members : 7
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1f08a1  ( 159 )                                                      
d1m55a-  (   1 )    matFYEViVrVPf---------dveehLpgIs------------------
d1p4da-  (   1 )      mMsIaqVr--sagsAGnyYtdkdnyyVLgsmgerWagrGAeqLglqgs
d1r9wa-  ( 210 )                                                      
d3l57a-  (   1 )      mLdIttItrqnVtsVvgyysdaddyys--ssfTsWqgtGAealglsgd
d4nbpa-  ( 135 )                                                      
d6q1ma-  (   7 )                                                      
                                                                      

                             60        70        80        90        100 
d1f08a1  ( 159 )    atvfklglFksLFlcsFhd--ITrlfkndkttnqqWVLAVfgLa------
d1m55a-  (  24 )    ---dsFvdwvt-------gqiwelpp-------------------eSdLn
d1p4da-  (  47 )    VdkdvFtrLLeGrLp--dgadlSrmqdgsnrHrpGydLtFsApkSVSMMA
d1r9wa-  ( 210 )    kqgamlavFkdtYglsFtd--LVr-------tctdWVTAIFgVn------
d3l57a-  (  50 )    VesarFkeLLvGeid--tfthMqR---gakkerLGYdLtFsApkgVSmqA
d4nbpa-  ( 135 )     dpdFpvdLhaf--Lsqav--f---------sntvasFAVYTt-------
d6q1ma-  (   7 )                                frvyskyLfLtYpqCtl-----
                       aaaaaaa                        bbbbbbb         

                             110       120       130       140       150 
d1f08a1  ( 201 )    ------------evffeaSfelLkkq--------------C-sFLQMqkr
d1m55a-  (  45 )    ltlVeqpqLTVAdrIrrvFLyeWnkfSk-----------qeSkfFVQFEk
d1p4da-  (  95 )    MLGgDkrLidAHnqAVdfAVrqVEalASTrvmtdgqsetvlTgnLVMALF
d1r9wa-  ( 252 )    ------------ptiAegFktlIqpf--------------I-lYAHIQcl
d3l57a-  (  98 )    lihgdktIieaHekAVaaAVreAeklAqArtg----svtqnTnnLVVATF
d4nbpa-  ( 166 )    ------------kekAqiLykkLmek--------------y-sVtFISrH
d6q1ma-  (  24 )    ----------ePqyALdsLrtlLnky--------------eplYIAAVre
                                aaaaaaaaaaaa                     bbbbb

                             160       170       180       190       200 
d1f08a1  ( 224 )    she-----ggtCAVYLIcFntaksRetVrnlManmLnv--reecLMLqPP
d1m55a-  (  84 )    gs-------eyfhLHTLVets---------------gIs-----------
d1p4da-  ( 145 )    NHDtsrdqePqLhThAVVANVTqhn-----------geWktL-ssdkvgk
d1r9wa-  ( 275 )    dck-----wgvLILALLrYkcgksrltVAkgLstlLhv--petcMLIqpP
d3l57a-  ( 148 )    Rhet---rdPdLhThAFVMNMTqred----------gqwraL-k------
d4nbpa-  ( 189 )    gfg-----g--hNILFFlTphrhrvsaInnyCqklCt----fsfLiCkgV
d6q1ma-  (  50 )    lhe----dgsphLHVLVQNlrAsI--tnpnaLn--lrmdtspfsifhPnI
                    bb        bbbbbbbbb  bb                           

                             210       220       230       240       250 
d1f08a1  ( 267 )    --ki-----rglsAAlfWfksslsp-------------------------
d1m55a-  ( 101 )    -------smvLgryVsqIraqLvkvVFq-giePqIn-dWVaitkvkkgga
d1p4da-  ( 183 )    tgFienVyanqiafGrlYrekLkeqVealGYeTevvgkhgmWeMpgVpve
d1r9wa-  ( 318 )    --kl-----rssvAAlyWyrtgisn-------------------------
d3l57a-  ( 181 )    ---ndeLmrnkmhLgdvYkqeLaleLtkagyeLrynsn-ntFdmAh    
d4nbpa-  ( 228 )    --n----------keylFYsaLcrq-------------------------
d6q1ma-  (  93 )    qaAk-----dCnqvrdyItkeVdsdv------------------------
                               aaaaaaaaaa                             

                             260       270       280       290       300 
d1f08a1  ( 285 )    -------------------aTlkhg-----alpewIraqttln       
d1m55a-  ( 142 )    nkvvdsgyIpayLLpkvQpeLQWAwTnldeYklAalnleeRkrLvaqfla
d1p4da-  ( 233 )    aFsvdpeikmaeWmqt-lketgfd--------irayrdaAdqradlrtlt
d1r9wa-  ( 336 )    -------------------iSevmg-----dtPewIqrlTiiq       
d3l57a-                                                               
d4nbpa-  ( 241 )    -------------------pYavveesiqgGLkehdfnpe          
d6q1ma-  ( 114 )    -------------------ntaewgtfvavs                   
                                         bbbb                         

                      
d1f08a1               
d1m55a-  ( 192 )    es
d1p4da-  ( 306 )    pg
d1r9wa-               
d3l57a-               
d4nbpa-               
d6q1ma-
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Replication initiation protein E1Replication initiation protein E1Bovine papillomavirus [TaxId: 10571]view
Replication protein Rep, nuclease domainReplication protein Rep, nuclease domainAdeno-associated virus, aav-5 [TaxId: 272636]view
F factor TraI relaxaseRelaxase domainEscherichia coli [TaxId: 562]view
Replication initiation protein E1Replication initiation protein E1Human papillomavirus type 18 [TaxId: 333761]view
automated matchesautomated matchesEscherichia coli [TaxId: 562]view
The origin DNA-binding domain of SV40 T-antigenThe origin DNA-binding domain of SV40 T-antigenJc polyomavirus [TaxId: 10632]view
automated matchesautomated matchesWheat dwarf virus [TaxId: 10834]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - A T V F K L G L F K S L F L C S F H D - - I T R L F K N D K T T N Q Q W V L A V F G L A - - - - - - - - - - - - - - - - - - E V F F E A S F E L L K K Q - - - - - - - - - - - - - - C - S F L Q M Q K R S H E - - - - - G G T C A V Y L I C F N T A K S R E T V R N L M A N M L N V - - R E E C L M L Q P P - - K I - - - - - R G L S A A L F W F K S S L S P - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - A T L K H G - - - - - A L P E W I R A Q T T L N - - - - - - - - -
M A T F Y E V I V R V P F - - - - - - - - - D V E E H L P G I S - - - - - - - - - - - - - - - - - - - - - D S F V D W V T - - - - - - - G Q I W E L P P - - - - - - - - - - - - - - - - - - - E S D L N L T L V E Q P Q L T V A D R I R R V F L Y E W N K F S K - - - - - - - - - - - Q E S K F F V Q F E K G S - - - - - - - E Y F H L H T L V E T S - - - - - - - - - - - - - - - G I S - - - - - - - - - - - - - - - - - - S M V L G R Y V S Q I R A Q L V K V V F Q - G I E P Q I N - D W V A I T K V K K G G A N K V V D S G Y I P A Y L L P K V Q P E L Q W A W T N L D E Y K L A A L N L E E R K R L V A Q F L A E S
- - M M S I A Q V R - - S A G S A G N Y Y T D K D N Y Y V L G S M G E R W A G R G A E Q L G L Q G S V D K D V F T R L L E G R L P - - D G A D L S R M Q D G S N R H R P G Y D L T F S A P K S V S M M A M L G G D K R L I D A H N Q A V D F A V R Q V E A L A S T R V M T D G Q S E T V L T G N L V M A L F N H D T S R D Q E P Q L H T H A V V A N V T Q H N - - - - - - - - - - - G E W K T L - S S D K V G K T G F I E N V Y A N Q I A F G R L Y R E K L K E Q V E A L G Y E T E V V G K H G M W E M P G V P V E A F S V D P E I K M A E W M Q T - L K E T G F D - - - - - - - - I R A Y R D A A D Q R A D L R T L T P G
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - K Q G A M L A V F K D T Y G L S F T D - - L V R - - - - - - - T C T D W V T A I F G V N - - - - - - - - - - - - - - - - - - P T I A E G F K T L I Q P F - - - - - - - - - - - - - - I - L Y A H I Q C L D C K - - - - - W G V L I L A L L R Y K C G K S R L T V A K G L S T L L H V - - P E T C M L I Q P P - - K L - - - - - R S S V A A L Y W Y R T G I S N - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - I S E V M G - - - - - D T P E W I Q R L T I I Q - - - - - - - - -
- - M L D I T T I T R Q N V T S V V G Y Y S D A D D Y Y S - - S S F T S W Q G T G A E A L G L S G D V E S A R F K E L L V G E I D - - T F T H M Q R - - - G A K K E R L G Y D L T F S A P K G V S M Q A L I H G D K T I I E A H E K A V A A A V R E A E K L A Q A R T G - - - - S V T Q N T N N L V V A T F R H E T - - - R D P D L H T H A F V M N M T Q R E D - - - - - - - - - - G Q W R A L - K - - - - - - - - - N D E L M R N K M H L G D V Y K Q E L A L E L T K A G Y E L R Y N S N - N T F D M A H - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - D P D F P V D L H A F - - L S Q A V - - F - - - - - - - - - S N T V A S F A V Y T T - - - - - - - - - - - - - - - - - - - K E K A Q I L Y K K L M E K - - - - - - - - - - - - - - Y - S V T F I S R H G F G - - - - - G - - H N I L F F L T P H R H R V S A I N N Y C Q K L C T - - - - F S F L I C K G V - - N - - - - - - - - - - K E Y L F Y S A L C R Q - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - P Y A V V E E S I Q G G L K E H D F N P E - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - F R V Y S K Y L F L T Y P Q C T L - - - - - - - - - - - - - - - E P Q Y A L D S L R T L L N K Y - - - - - - - - - - - - - - E P L Y I A A V R E L H E - - - - D G S P H L H V L V Q N L R A S I - - T N P N A L N - - L R M D T S P F S I F H P N I Q A A K - - - - - D C N Q V R D Y I T K E V D S D V - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - N T A E W G T F V A V S - - - - - - - - - - - - - - - - - - - - -

 

 

 

 

 

Member Chain UniProtKB GO term
d1r9wa_ A P06789 GO:0003677
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in