Superfamily : 55088 [ Methyl-coenzyme M reductase subunits ]
Class : Alpha and beta proteins (a+b)
Fold : Ferredoxin-like
# of Members : 5
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1e6yc-  (3002 )                                                      
d5a0ya1  (   2 )    adklfinalkkkfeespeekkttfytlggwkqSerktefVnaGkevaakr
d5a0yb1  (   2 )                                                      
d7b1sb1  (   2 )                                                      
d7b1sc-  (   2 )                                                      
                                                                      

                             60        70        80        90        100 
d1e6yc-  (3002 )                                      ayerqyypGatsVAan
d5a0ya1  (  52 )    gipqynpdigtplGqrvlmpyqvsttd------tyvegddlhfvnnaamq
d5a0yb1  (   2 )               akfedkvdlyd----drgnlveeqvplealsplrnpaik
d7b1sb1  (   2 )               ayltekidlyg----dngkvlesdipleavtpvqnpavr
d7b1sc-  (   2 )                                      vyqrqflpaddrVTkn
                                                                  aaaa

                             110       120       130       140       150 
d1e6yc-  (3018 )    rrkHmsg--kLeklreIsdedLTaVLghrapgs---------dypsthpp
d5a0ya1  (  96 )    qmwDdirR-----tViVGLnhahavIek-----rlgkeVtpetIthYLet
d5a0yb1  (  37 )    sivqgikr-----tVaVnLegIenaLktAkVgGpackim-----------
d7b1sb1  (  37 )    elasifkR-----sVaVnLggAqkaLstGhYAneyihfpdipnkdklg--
d7b1sc-  (  18 )    rkkVVdpsvkLekirtLsdkdFltLIghrhlge---------ayrsvnpp
                    aaaaaa            aaaaaaaa                        

                             160       170       180       190       200 
d1e6yc-  (3057 )    laemgepa-strenvaatpGaaaGDrvryIQFADSm------------yn
d5a0ya1  ( 136 )    VnhAMpgaavvqehmvethpalVadSyVkVfTGndeiadeIdpafVidin
d5a0yb1  (  71 )    --------------------------------------grel---dldIv
d7b1sb1  (  80 )    ----------------iksspggkyppksvk-------vrTm---dLpLv
d7b1sc-  (  59 )    laeigepedpirelvppteGakaGDrvCtIiMTDSv------------yn
                                                                      

                             210       220       230       240       250 
d1e6yc-  (3095 )    APAtpyfRsyFAainfr----gVdpgtls--grQiVeArErdMe------
d5a0ya1  ( 186 )    kqfpedqAetlkaevg-------------dgiwQvVrIPtivSrtc-dga
d5a0yb1  (  80 )    gn-AesIaaaAkemIqvtedddTnVellgggkrAlVqVPsarfdvaaeys
d7b1sb1  ( 104 )    dd-AddIaarLkerLqvnpddgTeVrvmkkgnvLyVkISeqlAntgveyt
d7b1sc-  (  97 )    PPIahyTRawMYhnrfr----gIdNgvys--grVtLeMrErdLe------
                        aaaaaaaaaaa        bbbb      bbbb  aaaaa      

                             260       270       280       290       300 
d1e6yc-  (3133 )    qCAkvQMetEITDHAlAGVRGatvhGhsvrlqedgVMfDmldRRrlen--
d5a0ya1  ( 222 )    tTsrwSAmqIgmSMis----Aykqaage-----aAtgdFayaAk----ae
d5a0yb1  ( 129 )    aAplvTAtAFvqAIin----efdvsm-------ydanMVkaAVLGrypqs
d7b1sb1  ( 153 )    tAlttTAqaMtdLVme----kydldf-------hAspLVhcAFyGrypqt
d7b1sc-  ( 135 )    eACrtLFEteICDASRDQVRQytctGhscrldpdgmMfDpieRCimsg--
                    aaaaaaaa                                          

                             310       320       330       340       350 
d1e6yc-  (3181 )    -----gtIiMdkDQvaipldrkVdLgkpMsseeAakrTTiYrvdn-vafr
d5a0ya1  ( 260 )    vihmg----------------t----------------------------
d5a0yb1  ( 168 )    veymgAnIatmldipqkl-egp                            
d7b1sb1  ( 192 )    yefmgGnVisllaascan-egp                            
d7b1sc-  ( 183 )    -----gnVvYqkdSfGnpVdtpInMgkplseeeLierTVvyrtdrgepmt
                           bb                                         

                             360       370       380       
d1e6yc-  (3225 )    ----------dDaeVvewvhrifdqrtkfgfqpk     
d5a0ya1  ( 266 )    -----------------------------------ylpv
d5a0yb1                                                    
d7b1sb1                                                    
d7b1sc-  ( 228 )    regDpgapdeeVrealqwsrriqwlrmlgnmvpdkikgm
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Methyl-coenzyme M reductase gamma chainMethyl-coenzyme M reductase gamma chainMethanosarcina barkeri [TaxId: 2208]view
automated matchesMethyl-coenzyme M reductase alpha and beta chain N-terminal domainMethanothermobacter marburgensis [TaxId: 145263]view
automated matchesMethyl-coenzyme M reductase alpha and beta chain N-terminal domainMethanothermobacter marburgensis [TaxId: 145263]view
automated matchesautomated matchesCandidatus ethanoperedens [TaxId: 2766897]view
automated matchesautomated matchesCandidatus ethanoperedens [TaxId: 2766897]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

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- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - A Y E R Q Y Y P G A T S V A A N R R K H M S G - - K L E K L R E I S D E D L T A V L G H R A P G S - - - - - - - - - D Y P S T H P P L A E M G E P A - S T R E N V A A T P G A A A G D R V R Y I Q F A D S M - - - - - - - - - - - - Y N A P A T P Y F R S Y F A A I N F R - - - - G V D P G T L S - - G R Q I V E A R E R D M E - - - - - - Q C A K V Q M E T E I T D H A L A G V R G A T V H G H S V R L Q E D G V M F D M L D R R R L E N - - - - - - - G T I I M D K D Q V A I P L D R K V D L G K P M S S E E A A K R T T I Y R V D N - V A F R - - - - - - - - - - D D A E V V E W V H R I F D Q R T K F G F Q P K - - - - -
A D K L F I N A L K K K F E E S P E E K K T T F Y T L G G W K Q S E R K T E F V N A G K E V A A K R G I P Q Y N P D I G T P L G Q R V L M P Y Q V S T T D - - - - - - T Y V E G D D L H F V N N A A M Q Q M W D D I R R - - - - - T V I V G L N H A H A V I E K - - - - - R L G K E V T P E T I T H Y L E T V N H A M P G A A V V Q E H M V E T H P A L V A D S Y V K V F T G N D E I A D E I D P A F V I D I N K Q F P E D Q A E T L K A E V G - - - - - - - - - - - - - D G I W Q V V R I P T I V S R T C - D G A T T S R W S A M Q I G M S M I S - - - - A Y K Q A A G E - - - - - A A T G D F A Y A A K - - - - A E V I H M G - - - - - - - - - - - - - - - - T - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Y L P V
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - A K F E D K V D L Y D - - - - D R G N L V E E Q V P L E A L S P L R N P A I K S I V Q G I K R - - - - - T V A V N L E G I E N A L K T A K V G G P A C K I M - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G R E L - - - D L D I V G N - A E S I A A A A K E M I Q V T E D D D T N V E L L G G G K R A L V Q V P S A R F D V A A E Y S A A P L V T A T A F V Q A I I N - - - - E F D V S M - - - - - - - Y D A N M V K A A V L G R Y P Q S V E Y M G A N I A T M L D I P Q K L - E G P - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - A Y L T E K I D L Y G - - - - D N G K V L E S D I P L E A V T P V Q N P A V R E L A S I F K R - - - - - S V A V N L G G A Q K A L S T G H Y A N E Y I H F P D I P N K D K L G - - - - - - - - - - - - - - - - - - I K S S P G G K Y P P K S V K - - - - - - - V R T M - - - D L P L V D D - A D D I A A R L K E R L Q V N P D D G T E V R V M K K G N V L Y V K I S E Q L A N T G V E Y T T A L T T T A Q A M T D L V M E - - - - K Y D L D F - - - - - - - H A S P L V H C A F Y G R Y P Q T Y E F M G G N V I S L L A A S C A N - E G P - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - V Y Q R Q F L P A D D R V T K N R K K V V D P S V K L E K I R T L S D K D F L T L I G H R H L G E - - - - - - - - - A Y R S V N P P L A E I G E P E D P I R E L V P P T E G A K A G D R V C T I I M T D S V - - - - - - - - - - - - Y N P P I A H Y T R A W M Y H N R F R - - - - G I D N G V Y S - - G R V T L E M R E R D L E - - - - - - E A C R T L F E T E I C D A S R D Q V R Q Y T C T G H S C R L D P D G M M F D P I E R C I M S G - - - - - - - G N V V Y Q K D S F G N P V D T P I N M G K P L S E E E L I E R T V V Y R T D R G E P M T R E G D P G A P D E E V R E A L Q W S R R I Q W L R M L G N M V P D K I K G M

 

 

 

 

 

Member Chain UniProtKB GO term
d1e6yc_ C P07962 GO:0005737
d1e6yc_ C P07962 GO:0015948
d1e6yc_ C P07962 GO:0016740
d1e6yc_ C P07962 GO:0050524
d1e6yc_ C P07955 GO:0005737
d1e6yc_ C P07955 GO:0015948
d1e6yc_ C P07955 GO:0016740
d1e6yc_ C P07955 GO:0050524
d1e6yc_ C P07964 GO:0005737
d1e6yc_ C P07964 GO:0015948
d1e6yc_ C P07964 GO:0016740
d1e6yc_ C P07964 GO:0050524
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in