Superfamily : 54675 [ Nicotinate/Quinolinate PRTase N-terminal domain-like ]
Class : Alpha and beta proteins (a+b)
Fold : alpha/beta-Hammerhead
# of Members : 17
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1o4ua2  (   1 )                       mkildlLmsfVkedegl--d----laSfpl-
d1qpoa2  (   2 )                glsdwelaaaraaIargldedlrygpd----vttlatv
d1vlpa1  (   2 )               sepvIksLldtd-yKit-HAavftnfp------------
d1x1oa1  (  10 )                     wqggleeaLrawlredlgqg-d----ltsllvv
d1ybea2  (   9 )        ttdiatrldpIVrsLidTdfyKLlmLqmIwklyp------------
d1yira2  (   4 )        aes--afserIVqnlldTdfykltmMqaVlhnyp------------
d2b7na1  (   1 )                       meirtfLeralkedlghg-d-----lfervl
d2i1oa1  (   1 )        mnvfntasdedikkGlasdvyFertisaigd--------------k
d2im5a1  (   3 )                  iIrsIldtdlyKfttGyayaklfp------------
d3os4a1  (   3 )             qdaspIltslldtdayklh-qqaVfhhyr------------
d3paja1  (   1 )    mkethnsqdrlaylkqqlpadItrsVidtLkedLggtldpaaditAsl-i
d4hl7a1  (   4 )          nprlfsphIIrsLldLdayKIn--qaihhfyp------------
d4kfna1  (   8 )                  efNILlaTdsyKVthykqypp-------------nt
d4mzya1  (   4 )             tya--ddslTlhTdmyQInmMqtywe-------------lg
d5huoa1  (   6 )                  tdltpfqiddtLkaalredvhse-d----ystnaif
                                           aaaaaaaaaaa                

                             60        70        80        90        100 
d1o4ua2  (  27 )    -rnttagahlllk----------tenvvAsGIevSrm-FLekmg------
d1qpoa2  (  36 )    pasatttaslvtr----------e-agvVagLdVAll-TLnevLg-----
d1vlpa1  (  29 )    --dvtvtykytnrssqltFneA-in----wLkeQFsy-Lgn-lrFteeei
d1x1oa1  (  38 )    pedlegeavilak----------e-ggvlaGLwvAer-VFaLAdp-----
d1ybea2  (  51 )    --evdatfslinrtktvlAeeIdem----eLreQLdh-Art-lrLskken
d1yira2  (  36 )    --naevewefrcrnqedL-rly-lp----aIreqley-Lag-laIsdeql
d2b7na1  (  26 )    ekdfkatafvrak----------q-egvFsgekyAle-LLemtg------
d2i1oa1  (  33 )    çndlrvameatvs-------gpldtwinFtgldeVlk-LLe---------
d2im5a1  (  27 )    --raygefrfidrnrqgfteeF-Ae----lVrgeIra-Maa-lsLtrdek
d3os4a1  (  32 )    --hitvaaefrcrsdell-GvY-Ad----eIrhQvt--lgq-laLtsdef
d3paja1  (  50 )    padristatiitr----------e-agvFcGqlwAde-VFkqLgg-----
d4hl7a1  (  36 )    --dvsvryeliv------eAgL-ld----aIrqeiah-Lgt-lrFsdadI
d4kfna1  (  31 )    s---kvysyfecre--kkye-----etvFygLqyIlnkyLkgkvVtkekI
d4mzya1  (  30 )    radlhavfecyfrempfnhg-----yaiFaGlerLvn-YlenLtFt----
d5huoa1  (  38 )    h-hgqakvslfak----------e-agvLagLtVFqr-VFtlfd------
                        bbbbb                      aaaaaa a           

                             110       120       130       140       150 
d1o4ua2  (  59 )    ----------------------------------LlskFnV--edgeyle
d1qpoa2  (  69 )    ---------------------------------tngyrvldrvedgarVp
d1vlpa1  (  71 )    eyLkqeip------yLpsaYiyIsssnykLhPeeq-Isftsei-------
d1x1oa1  (  71 )    ---------------------------------rTaFtplv--aegarva
d1ybea2  (  94 )    iwLagntfy-grsqiFepeFLswL--syqLpe----yeLk----------
d1yira2  (  76 )    afler-ip------fLapdFirfLg-lFrFnp-ry-Vqtgien-------
d2b7na1  (  58 )    ------------------------------------Iecvqtikdkerfk
d2i1oa1  (  66 )    -------------------------------gld--Vdlya-ipegtilf
d2im5a1  (  68 )    efLqrelp------yLppiYIdfLd-gFrFdp-ee-VtVsida-------
d3os4a1  (  72 )    iyLss-lp------fFqddYLhwLr-dfrfkp-eq-VsVavhd-------
d3paja1  (  83 )    ---------------------------------qVsIewhV--qdgdtLt
d4hl7a1  (  76 )    hyltqhap------hLkatFLsLr--yfhFvPqeq-ve-giv--------
d4kfna1  (  81 )    qeAkdvYkehfqddvFnekgWnyIlek---ydGhLPIeika-vpegfvip
d4mzya1  (  70 )    esdiayLrevee---YpedFLtyLa------nFefkCtvrs-alegdlVf
d5huoa1  (  69 )    ---------------------------------eVtfqnphqfkdgdrlt
                                                        bbb           

                             160       170       180       190  
d1o4ua2  (  73 )    gt------gviGeIegntykllVAerTLlnvlsvmfs       
d1qpoa2  (  86 )    pg------eaLMtLeAqtrglltAerTMlnlvghlsg       
d1vlpa1  ( 109 )    --egkpthyLkIlVsgs-wkdTiLYeipLlsLiseAyfkfvd  
d1x1oa1  (  86 )    eg------teVArVrgplrgIlaGerlAlnlLqrlsg       
d1ybea2  ( 130 )    ------dgqYeLnFhgr-wmdTTLWeipAlsIineLrsrsam  
d1yira2  ( 109 )    -------deFfLrLkgp-wLhVILFevPLlaMiseVrnrarypa
d2b7na1  (  72 )    pk------dalMeIrgdfsmllkVertLlnlLqhssg       
d2i1oa1  (  82 )    PrdanglpvpFIrVegryçdFGmyetailgficqasgi      
d2im5a1  ( 102 )    ------qghLdIrAqgl-lyrVTLWetPilaViseLyyrfiga 
d3os4a1  ( 105 )    -------gkLdIriagl-wCeVi-WevpllaVIseIvhrrrstq
d3paja1  (  98 )    pn------qtLCtLtgpArillTGerNAmnfiqtlsg       
d4hl7a1  ( 115 )    --------qqLIsIrgs-wrdTilYetLV-aIvseVrsrqrwae
d4kfna1  ( 127 )    rg------nvLFtVeNtdpeCyWLTnWIetiLvq-SwypItvat
d4mzya1  ( 110 )    nn------epLIqiegp----lAQCqLVetALlnmVnfqtl   
d5huoa1  (  86 )    sg------dlVLeIiGsvrSLltCerVAlnflqhlsg       
                              bbbbbbb aaaa   aaaaaaaaaaa
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), N-terminal domainNadC N-terminal domain-likeThermotoga maritima [TaxId: 2336]view
Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), N-terminal domainNadC N-terminal domain-likeMycobacterium tuberculosis [TaxId: 1773]view
Nicotinate phosphoribosyltransferase, N-terminal domainMonomeric nicotinate phosphoribosyltransferase N-terminal domain-likeBaker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]view
automated matchesautomated matchesThermus thermophilus HB8 [TaxId: 300852]view
Nicotinate phosphoribosyltransferase, N-terminal domainMonomeric nicotinate phosphoribosyltransferase N-terminal domain-likeAgrobacterium tumefaciens [TaxId: 358]view
Nicotinate phosphoribosyltransferase, N-terminal domainMonomeric nicotinate phosphoribosyltransferase N-terminal domain-likePseudomonas aeruginosa [TaxId: 287]view
automated matchesautomated matchesHelicobacter pylori [TaxId: 210]view
Nicotinate phosphoribosyltransferase Ta1145NadC N-terminal domain-likeThermoplasma acidophilum [TaxId: 2303]view
Nicotinate phosphoribosyltransferase, N-terminal domainMonomeric nicotinate phosphoribosyltransferase N-terminal domain-likePorphyromonas gingivalis [TaxId: 837]view
automated matchesautomated matchesYersinia pestis [TaxId: 214092]view
automated matchesautomated matchesVibrio cholerae [TaxId: 243277]view
automated matchesautomated matchesVibrio cholerae [TaxId: 243277]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view
Putative nicotinate phosphoribosyltransferase EF2626NadC N-terminal domain-likeEnterococcus faecalis [TaxId: 1351]view
automated matchesautomated matchesStreptococcus pyogenes [TaxId: 1115816]view
Domain ID Name
d3l0ga13l0g A:3-107
d3tqva13tqv A:7-119
Created with Raphaëld4hl7a1d1vlpa1d1ybea2d2im5a1d3os4a1d1yira2d2b7na1d1o4ua2d3paja1d5huoa1d1x1oa1d1qpoa2d4kfna1d4mzya1d2i1oa1
FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
- - - - - - - - - - - - - - - - - - - M K I L D L L M S F V K E D E G L - - D - - - - L A S F P L - - R N T T A G A H L L L K - - - - - - - - - - T E N V V A S G I E V S R M - F L E K M G - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - L L S K F N V - - E D G E Y L E G T - - - - - - G V I G E I E G N T Y K L L V A E R T L L N V L S V M F S - - - - - - -
- - - - - - - - - - - - G L S D W E L A A A R A A I A R G L D E D L R Y G P D - - - - V T T L A T V P A S A T T T A S L V T R - - - - - - - - - - E - A G V V A G L D V A L L - T L N E V L G - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - T N G Y R V L D R V E D G A R V P P G - - - - - - E A L M T L E A Q T R G L L T A E R T M L N L V G H L S G - - - - - - -
- - - - - - - - - - - S E P V I K S L L D T D - Y K I T - H A A V F T N F P - - - - - - - - - - - - - - D V T V T Y K Y T N R S S Q L T F N E A - I N - - - - W L K E Q F S Y - L G N - L R F T E E E I E Y L K Q E I P - - - - - - Y L P S A Y I Y I S S S N Y K L H P E E Q - I S F T S E I - - - - - - - - - E G K P T H Y L K I L V S G S - W K D T I L Y E I P L L S L I S E A Y F K F V D - -
- - - - - - - - - - - - - - - - - W Q G G L E E A L R A W L R E D L G Q G - D - - - - L T S L L V V P E D L E G E A V I L A K - - - - - - - - - - E - G G V L A G L W V A E R - V F A L A D P - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - R T A F T P L V - - A E G A R V A E G - - - - - - T E V A R V R G P L R G I L A G E R L A L N L L Q R L S G - - - - - - -
- - - - T T D I A T R L D P I V R S L I D T D F Y K L L M L Q M I W K L Y P - - - - - - - - - - - - - - E V D A T F S L I N R T K T V L A E E I D E M - - - - E L R E Q L D H - A R T - L R L S K K E N I W L A G N T F Y - G R S Q I F E P E F L S W L - - S Y Q L P E - - - - Y E L K - - - - - - - - - - - - - - - - D G Q Y E L N F H G R - W M D T T L W E I P A L S I I N E L R S R S A M - -
- - - - A E S - - A F S E R I V Q N L L D T D F Y K L T M M Q A V L H N Y P - - - - - - - - - - - - - - N A E V E W E F R C R N Q E D L - R L Y - L P - - - - A I R E Q L E Y - L A G - L A I S D E Q L A F L E R - I P - - - - - - F L A P D F I R F L G - L F R F N P - R Y - V Q T G I E N - - - - - - - - - - - - - - D E F F L R L K G P - W L H V I L F E V P L L A M I S E V R N R A R Y P A
- - - - - - - - - - - - - - - - - - - M E I R T F L E R A L K E D L G H G - D - - - - - L F E R V L E K D F K A T A F V R A K - - - - - - - - - - Q - E G V F S G E K Y A L E - L L E M T G - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - I E C V Q T I K D K E R F K P K - - - - - - D A L M E I R G D F S M L L K V E R T L L N L L Q H S S G - - - - - - -
- - - - M N V F N T A S D E D I K K G L A S D V Y F E R T I S A I G D - - - - - - - - - - - - - - K C N D L R V A M E A T V S - - - - - - - G P L D T W I N F T G L D E V L K - L L E - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G L D - - V D L Y A - I P E G T I L F P R D A N G L P V P F I R V E G R Y C D F G M Y E T A I L G F I C Q A S G I - - - - - -
- - - - - - - - - - - - - - I I R S I L D T D L Y K F T T G Y A Y A K L F P - - - - - - - - - - - - - - R A Y G E F R F I D R N R Q G F T E E F - A E - - - - L V R G E I R A - M A A - L S L T R D E K E F L Q R E L P - - - - - - Y L P P I Y I D F L D - G F R F D P - E E - V T V S I D A - - - - - - - - - - - - - Q G H L D I R A Q G L - L Y R V T L W E T P I L A V I S E L Y Y R F I G A -
- - - - - - - - - Q D A S P I L T S L L D T D A Y K L H - Q Q A V F H H Y R - - - - - - - - - - - - - - H I T V A A E F R C R S D E L L - G V Y - A D - - - - E I R H Q V T - - L G Q - L A L T S D E F I Y L S S - L P - - - - - - F F Q D D Y L H W L R - D F R F K P - E Q - V S V A V H D - - - - - - - - - - - - - - G K L D I R I A G L - W C E V I - W E V P L L A V I S E I V H R R R S T Q
M K E T H N S Q D R L A Y L K Q Q L P A D I T R S V I D T L K E D L G G T L D P A A D I T A S L - I P A D R I S T A T I I T R - - - - - - - - - - E - A G V F C G Q L W A D E - V F K Q L G G - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Q V S I E W H V - - Q D G D T L T P N - - - - - - Q T L C T L T G P A R I L L T G E R N A M N F I Q T L S G - - - - - - -
- - - - - - N P R L F S P H I I R S L L D L D A Y K I N - - Q A I H H F Y P - - - - - - - - - - - - - - D V S V R Y E L I V - - - - - - E A G L - L D - - - - A I R Q E I A H - L G T - L R F S D A D I H Y L T Q H A P - - - - - - H L K A T F L S L R - - Y F H F V P Q E Q - V E - G I V - - - - - - - - - - - - - - - - Q Q L I S I R G S - W R D T I L Y E T L V - A I V S E V R S R Q R W A E
- - - - - - - - - - - - - - E F N I L L A T D S Y K V T H Y K Q Y P P - - - - - - - - - - - - - N T S - - - K V Y S Y F E C R E - - K K Y E - - - - - E T V F Y G L Q Y I L N K Y L K G K V V T K E K I Q E A K D V Y K E H F Q D D V F N E K G W N Y I L E K - - - Y D G H L P I E I K A - V P E G F V I P R G - - - - - - N V L F T V E N T D P E C Y W L T N W I E T I L V Q - S W Y P I T V A T
- - - - - - - - - T Y A - - D D S L T L H T D M Y Q I N M M Q T Y W E - - - - - - - - - - - - - L G R A D L H A V F E C Y F R E M P F N H G - - - - - Y A I F A G L E R L V N - Y L E N L T F T - - - - E S D I A Y L R E V E E - - - Y P E D F L T Y L A - - - - - - N F E F K C T V R S - A L E G D L V F N N - - - - - - E P L I Q I E G P - - - - L A Q C Q L V E T A L L N M V N F Q T L - - -
- - - - - - - - - - - - - - T D L T P F Q I D D T L K A A L R E D V H S E - D - - - - Y S T N A I F H - H G Q A K V S L F A K - - - - - - - - - - E - A G V L A G L T V F Q R - V F T L F D - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - E V T F Q N P H Q F K D G D R L T S G - - - - - - D L V L E I I G S V R S L L T C E R V A L N F L Q H L S G - - - - - - -

 

 

 

 

 

 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in