Superfamily : 54403 [ Cystatin/monellin ]
Class : Alpha and beta proteins (a+b)
Fold : Cystatin-like
# of Members : 18
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1x9ya2  (  41 )                                 kqLeInVksdkvPqkVkdlAq
d2bk7b1  (   1 )                                   mei-------ppt-nypAs
d2bk7b2  (  99 )              pdeedntfYqrLksmkepleaqnIpdnfgnvspe-mtlVL
d2ch9a1  (  25 )    tcsqdlnsrv----------------kpgfpkti-------ktn-dpgVl
d2gu3a1  (  99 )                                                 gised
d2gu3a2  (  34 )                                                keeghe
d2octa-  (   2 )                                 ms-gapsatqpataetqhiad
d3mwza1  (   2 )                                  elalrggyrersnqddpeyl
d4eyca1  (  31 )                                                qvlsyk
d4it7a-  (   6 )                                ggfstk-------dvn-dpkIq
d4n6ob1  (  11 )                                gelrdl-------spd-dpqVq
d5o46a-  (   1 )                                  f---pgvwrkhhpdvdprYk
d5zc1a-  (  36 )          vmpi----------------cggisaar-------iPt-adekk
d6uioa-  (  31 )                              aqnyfgsi-------nis-nanvk
d6ztka-  (  13 )                                        gwktqdpt-npkfe
                                                                  aaaa

                             60        70        80        90        100 
d1x9ya2  (  62 )    qqfagyAkalDkqsnaktgkyeLGeAFKIYkfnGeednSYyyPVIkdgkI
d2bk7b1  (  12 )    rAAlvAqnyInyqqGtphrvFevqkVkqAsmedip----------grghk
d2bk7b2  ( 138 )    hLAwvACgyIiwqnstedtwykMvkIqtVkQvqrn----------ddfIE
d2ch9a1  (  51 )    qAArySVekfnnctndm-flFkesrItrAlvqiv------------kGlk
d2gu3a1  ( 104 )    kAakiIkdeg-----------lvskqkeVhlare-----------gnvlL
d2gu3a2  (  40 )    aAaaeAkket-----------dLahvdqvetfvg------------keky
d2octa-  (  22 )    q-vrsqleeky---nkkfpvfkavsfks-------------qvv----ag
d3mwza1  (  22 )    e-AhyATstwSaqqpgkthfDTVveV-kVeTQtv------------agtN
d4eyca1  (  37 )    eAVlrAIdgInqrssd-anlYrlldldprtmd--g----------dpdtp
d4it7a-  (  20 )    aLAgkAlqrInaasndl-fqQtivkVisAktqvv------------agtn
d4n6ob1  (  25 )    kAAqaAVasyNmgsnsi-yYfrdthiikAqsqlv------------aGik
d5o46a-  (  18 )    eWAhfAIssqv---enrtnfDTlmtLisVesqvi------------agvD
d5zc1a-  (  56 )    kLepvLlqsLyahlg---skPtsAeVvlVAtqvv------------agtN
d6uioa-  (  47 )    qAvwfAMkeynkesedk-yvFlvdkilhAklqit------------drme
d6ztka-  (  26 )    nlAhyAVstqv---egreyydTVleLleVqtqiv------------aGvn
                    aaaaaaaaa a         bbbbbbbbbbbb                bb

                             110       120       130       140       150 
d1x9ya2  ( 112 )    vyTLtLsPkn---kdDlnkskedmnYsVkisnfIAkdLdqikdknsnITV
d2bk7b1  (  52 )    yrLkFaVeEiiqk--------------------------------qvkvn
d2bk7b2  ( 178 )    LdYtIlLhniasq---------------------------------eiip
d2ch9a1  (  88 )    YmLeVeIgrTtçkkn----q----------hlrLddÇdfQtnhtlkqtls
d2gu3a1  ( 132 )    weVTYldke--------------------------------------gqy
d2gu3a2  (  67 )    yvVkGtdkk--------------------------------------gta
d2octa-  (  51 )    tnyfikvhvg---d-------------------------------edfvH
d3mwza1  (  60 )    yrLtLkVAeStçelt--s------------tynkdtÇqAna---naaqrt
d4eyca1  (  75 )    KpVSFtVkeTvÇprttq--------------qspedÇdfkk---dGlvkr
d4it7a-  (  57 )    TvLeLlIApTsçrknetsag---------------nçeavs---nGtkqi
d4n6ob1  (  62 )    YfLtMeMgSTdcrktrvtgd----------hvdlttCplAag-aqqeklr
d5o46a-  (  53 )    ykLkMkVAeStÇvigv-d------------syskerÇylkv---nvpyMl
d5zc1a-  (  91 )    YFAKVkVnn--------------------------------------dhy
d6uioa-  (  84 )    YqidvqisrSnÇkkplnnte---------------nÇipqkkpelekkms
d6ztka-  (  61 )    ykLkFtTTqStçkiesgv------------eYskelÇqpkt---nkveav
                    bbbbbbbb                                        bb

                             160       170       180       190       200 
d1x9ya2  ( 159 )    LtdekGfYFeed--g--kvrlVkatp--lanNikekesaktVspqLkqel
d2bk7b1  (  70 )    CtA---eVlypstg---qetapeVnftfe--getgkn             
d2bk7b2  ( 195 )    wqM---qVlwhPq---ygtkVkhnsrlpk                     
d2ch9a1  ( 124 )    ÇyS---eVwvVpwl--qhfeVpvlrçh                       
d2gu3a1  ( 144 )    SlS---yVdft---tG---kilknitp                       
d2gu3a2  (  79 )    lyV---wVPad---kk---akilskeake                     
d2octa-  (  67 )    lrv---fqslph--enksltlsnyqtnkak------------------hd
d3mwza1  (  93 )    ÇtT---viyrnq----geksinsFeçaaa                     
d4eyca1  ( 108 )    Çmg---tVtlnqarg-----sfdIsÇdkdnk                   
d4it7a-  (  89 )    ÇtV---aIwekpwe--nfeeItikeçksa                     
d4n6ob1  ( 101 )    ÇdF---eVlvvpwq--nssqLlkhnçvqm                     
d5o46a-  (  87 )    ÇtA---vVnympwe--hktilksYdçsdrvygv                 
d5zc1a-  ( 103 )    IHT---rVyeqlpcyggaleLhsVqmnktdtdpLdyf             
d6uioa-  ( 119 )    ÇsF---lvGAlPwn--geFnllskeçkdv                     
d6ztka-  (  96 )    ÇtS---iIytvpwq--nikrvlsYhçdap                     
                    bbb   bbbb        bbbbbbbb                        

                             
d1x9ya2  ( 203 )    kttVtPtkv
d2bk7b1                      
d2bk7b2                      
d2ch9a1                      
d2gu3a1                      
d2gu3a2                      
d2octa-  (  94 )    eltyf    
d3mwza1                      
d4eyca1                      
d4it7a-                      
d4n6ob1                      
d5o46a-                      
d5zc1a-                      
d6uioa-                      
d6ztka-
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Staphopain B, prodomainStaphopain B, prodomainStaphylococcus aureus [TaxId: 1280]view
LatexinLatexin-likeHuman (Homo sapiens) [TaxId: 9606]view
LatexinLatexin-likeHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view
Uncharacterized protein YpmBPepSY-likeBacillus subtilis [TaxId: 1423]view
Uncharacterized protein YpmBPepSY-likeBacillus subtilis [TaxId: 1423]view
automated matchesCystatinsHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesIxodes scapularis [TaxId: 6945]view
automated matchesCathelicidin motifHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesAscaris lumbricoides [TaxId: 6252]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesIxodes ricinus [TaxId: 34613]view
automated matchesautomated matchesClonorchis sinensis [TaxId: 79923]view
automated matchesautomated matchesMouse (Mus musculus) [TaxId: 10090]view
automated matchesautomated matchesIxodes ricinus [TaxId: 34613]view
Domain ID Name
d6vlpa-6vlp A:
d2o9ux-2o9u X:
d3nx0a-3nx0 A:
FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - K Q L E I N V K S D K V P Q K V K D L A Q Q Q F A G Y A K A L D K Q S N A K T G K Y E L G E A F K I Y K F N G E E D N S Y Y Y P V I K D G K I V Y T L T L S P K N - - - K D D L N K S K E D M N Y S V K I S N F I A K D L D Q I K D K N S N I T V L T D E K G F Y F E E D - - G - - K V R L V K A T P - - L A N N I K E K E S A K T V S P Q L K Q E L K T T V T P T K V
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - M E I - - - - - - - P P T - N Y P A S R A A L V A Q N Y I N Y Q Q G T P H R V F E V Q K V K Q A S M E D I P - - - - - - - - - - G R G H K Y R L K F A V E E I I Q K - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Q V K V N C T A - - - E V L Y P S T G - - - Q E T A P E V N F T F E - - G E T G K N - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - P D E E D N T F Y Q R L K S M K E P L E A Q N I P D N F G N V S P E - M T L V L H L A W V A C G Y I I W Q N S T E D T W Y K M V K I Q T V K Q V Q R N - - - - - - - - - - D D F I E L D Y T I L L H N I A S Q - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - E I I P W Q M - - - Q V L W H P Q - - - Y G T K V K H N S R L P K - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
T C S Q D L N S R V - - - - - - - - - - - - - - - - K P G F P K T I - - - - - - - K T N - D P G V L Q A A R Y S V E K F N N C T N D M - F L F K E S R I T R A L V Q I V - - - - - - - - - - - - K G L K Y M L E V E I G R T T C K K N - - - - Q - - - - - - - - - - H L R L D D C D F Q T N H T L K Q T L S C Y S - - - E V W V V P W L - - Q H F E V P V L R C H - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G I S E D K A A K I I K D E G - - - - - - - - - - - L V S K Q K E V H L A R E - - - - - - - - - - - G N V L L W E V T Y L D K E - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G Q Y S L S - - - Y V D F T - - - T G - - - K I L K N I T P - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - K E E G H E A A A A E A K K E T - - - - - - - - - - - D L A H V D Q V E T F V G - - - - - - - - - - - - K E K Y Y V V K G T D K K - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G T A L Y V - - - W V P A D - - - K K - - - A K I L S K E A K E - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - M S - G A P S A T Q P A T A E T Q H I A D Q - V R S Q L E E K Y - - - N K K F P V F K A V S F K S - - - - - - - - - - - - - Q V V - - - - A G T N Y F I K V H V G - - - D - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - E D F V H L R V - - - F Q S L P H - - E N K S L T L S N Y Q T N K A K - - - - - - - - - - - - - - - - - - H D E L T Y F - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - E L A L R G G Y R E R S N Q D D P E Y L E - A H Y A T S T W S A Q Q P G K T H F D T V V E V - K V E T Q T V - - - - - - - - - - - - A G T N Y R L T L K V A E S T C E L T - - S - - - - - - - - - - - - T Y N K D T C Q A N A - - - N A A Q R T C T T - - - V I Y R N Q - - - - G E K S I N S F E C A A A - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Q V L S Y K E A V L R A I D G I N Q R S S D - A N L Y R L L D L D P R T M D - - G - - - - - - - - - - D P D T P K P V S F T V K E T V C P R T T Q - - - - - - - - - - - - - - Q S P E D C D F K K - - - D G L V K R C M G - - - T V T L N Q A R G - - - - - S F D I S C D K D N K - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - G G F S T K - - - - - - - D V N - D P K I Q A L A G K A L Q R I N A A S N D L - F Q Q T I V K V I S A K T Q V V - - - - - - - - - - - - A G T N T V L E L L I A P T S C R K N E T S A G - - - - - - - - - - - - - - - N C E A V S - - - N G T K Q I C T V - - - A I W E K P W E - - N F E E I T I K E C K S A - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - G E L R D L - - - - - - - S P D - D P Q V Q K A A Q A A V A S Y N M G S N S I - Y Y F R D T H I I K A Q S Q L V - - - - - - - - - - - - A G I K Y F L T M E M G S T D C R K T R V T G D - - - - - - - - - - H V D L T T C P L A A G - A Q Q E K L R C D F - - - E V L V V P W Q - - N S S Q L L K H N C V Q M - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - F - - - P G V W R K H H P D V D P R Y K E W A H F A I S S Q V - - - E N R T N F D T L M T L I S V E S Q V I - - - - - - - - - - - - A G V D Y K L K M K V A E S T C V I G V - D - - - - - - - - - - - - S Y S K E R C Y L K V - - - N V P Y M L C T A - - - V V N Y M P W E - - H K T I L K S Y D C S D R V Y G V - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - V M P I - - - - - - - - - - - - - - - - C G G I S A A R - - - - - - - I P T - A D E K K K L E P V L L Q S L Y A H L G - - - S K P T S A E V V L V A T Q V V - - - - - - - - - - - - A G T N Y F A K V K V N N - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - D H Y I H T - - - R V Y E Q L P C Y G G A L E L H S V Q M N K T D T D P L D Y F - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - A Q N Y F G S I - - - - - - - N I S - N A N V K Q A V W F A M K E Y N K E S E D K - Y V F L V D K I L H A K L Q I T - - - - - - - - - - - - D R M E Y Q I D V Q I S R S N C K K P L N N T E - - - - - - - - - - - - - - - N C I P Q K K P E L E K K M S C S F - - - L V G A L P W N - - G E F N L L S K E C K D V - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G W K T Q D P T - N P K F E N L A H Y A V S T Q V - - - E G R E Y Y D T V L E L L E V Q T Q I V - - - - - - - - - - - - A G V N Y K L K F T T T Q S T C K I E S G V - - - - - - - - - - - - E Y S K E L C Q P K T - - - N K V E A V C T S - - - I I Y T V P W Q - - N I K R V L S Y H C D A P - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

 

 

 

 

 

Member Chain UniProtKB GO term
d1x9ya2 A P0C1S6 GO:0005576
d1x9ya2 A P0C1S6 GO:0006508
d1x9ya2 A P0C1S6 GO:0008234
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in