PASS2.8 - Home

solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x

beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x

hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x

                             10        20        30        40        50  
d1jr1b1  (  11 )         syvpddgltAqqLFnc-------gdgLtYndFlilpgyi--dFta
d1mwfa1  (   2 )    akyyn-----------------------epchtFneyllipglstvdCip
d2c6qa1  (  10 )                                   ldFkdVllrpkrstLk-sr
d6d4ra-  (  15 )                    vptggddptkiamlgltFddVlllpaas--dvlp
                                                     333bbb          3

                             60        70        80        90        100 
d1jr1b1  (  47 )    dqVdLtsaLTk-------kitLkTPLVSSPmdtVTeagMAiAMAltGGIG
d1mwfa1  (  29 )    snVnLsTpLVkfqkgqqSeinLkiPLVSaImqSVSgekMAiaLAregGIS
d2c6qa1  (  28 )    seVdLtrsFs--FrnSkqtYsg-vPIIAanmDTVGTfeMAkvLçkfsLFT
d6d4ra-  (  47 )    anAdTsSqLTk-------kirLkvPLVSsamdtVTearMAiaMAragGMG
                    33    bb            bb   bbb        aaaaaaaaa   bb

                             110       120       130       140       150 
d1jr1b1  (  90 )    FIHhnctpefQanEVrkVkkyeqyplAskdakkqLlCGAAIgthedDkyr
d1mwfa1  (  79 )    FIfgsqsiesQaamVhaVknf------------rylVGAGInt-rdFreR
d2c6qa1  (  75 )    AVhkhys----lvqWqefag--------qnpdçLehLAASSgtgssdfeq
d6d4ra-  (  90 )    VLHrnlpvaeQaaqVetVkrsg-----------gllVGAAVgvgddAwer
                    bb     aaaaaaaaaaaa                  bbbb     aaaa

                             160       170       180       190       200 
d1jr1b1  ( 260 )    LdlLalag--VdVVVLdssqGnsifQinMIkyMkekyp-nlQVIGGnVvt
d1mwfa1  ( 247 )    VpaLveag--AdVLCIdssdGfsewQkiTIgwIrdkygdkvkVGAGNIvd
d2c6qa1  ( 113 )    LeqiLeaIpqVkYICLdvanGysehFVefVkdVrkrFp-qhTIMAGnVvt
d6d4ra-  ( 129 )    AmaLrdAg--VdVLVVdtahAhn--VldmVhrLkttvG-diEVVGGnVat
                    aaaaaaa     bbbb       aaaaaaaaaaaaa     bbbbbbb  

                             210       220       230       240       250 
d1jr1b1  ( 307 )    aaqAknLidAgVdALrVGMgcgsi-itqevlacGrpQAtAVYkVSeyArr
d1mwfa1  ( 295 )    geGFryLAdAgADFIKIGiGggsiciTreqkgiGrgQAtAVidVvaeRnk
d2c6qa1  ( 162 )    gemVeeLIlsgADIIKVGiGpgsVcttrkktgvgypQLsAVmeCAdaAhg
d6d4ra-  ( 177 )    raAAaaLveagADAVKVGvGpgsicttrvvagvGapQItAIleAvaaCap
                    aaaaaaaaaa   bbbb         aaaa      aaaaaaaaaaaa  

                             260       270       280       290       300 
d1jr1b1  ( 357 )    f------gVpVIAdggIqnvghIakALALGAsTVMMgslLAATteApgey
d1mwfa1  ( 345 )    yfeetgiyIPVCSdggIvydyHMTLALAMgADFIMLGryFArFeeSpTrk
d2c6qa1  ( 212 )    l------kGhIISdggCscpgdVAkAFGAgADFVMLggmLAGHseSggel
d6d4ra-  ( 227 )    h------gVpVIAdggLqysgDIAkALAAgAsTAMLgslLAgTaeSpgel
                              bbbb     aaaaaaaaa    bbbb aaaa        b

                             310       320       330       340       350 
d1jr1b1  ( 401 )    ffsdgirlKkYrgmgSldAmi------------kvaqgvsgavqdkgsIh
d1mwfa1  ( 395 )    vtingsvmKeYwGEGSsrArNwqrydlggkqklsfeEGvdsyvpyagkLk
d2c6qa1  ( 256 )    ierdgkkyklFYgmsSemAmkkyaggvae---yraseGktvevpfkgdVe
d6d4ra-  ( 271 )    ilvg--qfKsYrGmgSlgAml-------------vpeGiegrvpf-gpLs
                    bb    bbbbbb                           bbbbb    aa

                             360       370       380       390       400 
d1jr1b1  ( 455 )    kfVpyLiagIqhsCqdIGAksLtqVramMysgeLkFekrtssaqveggvh
d1mwfa1  ( 445 )    dnVeaSlnkVkstMcnCGAltIpqLqs-----kAkitlvssvsiveggah
d2c6qa1  ( 303 )    htIrdILggIrstCtyVGAakLkeLsr-----rTtfirv           
d6d4ra-  ( 332 )    tvIhqlvggLraaMgyTGSatIeeLqq------aqfvqitaagl      
                    aaaaaaaaaaaaaaaaa    aaaaaa        bbb            

                             410 
d1jr1b1  ( 505 )    slhsyekrlf
d1mwfa1  ( 490 )    dvivk     
d2c6qa1                       
d6d4ra-

Domains
Outliers

Domain ID	Name	Family	Source	STRING-DB
d1jr1b1 # Domain Specific Files ATM file: Atomic coordinates by ASTRAL ATM2ALI file: Amino acid sequences by ATM2ALI SST file: Secondary structure by SSTRUC PSA file: solvent accessibility by PSA HBD file: Hydrogen bonds by HBOND PSE file: PyMol session file for conserved interactions PDBSUM1: Topological diagram d1jr1b1 # Links to other databases and tools RCSB-PDB: Research Collaboratory for Structural Bioinformatics SCOP: Structural Classification of Proteins EBI: European Bioinformatics Institute HOMSTRAD: Homologous Structure Alignment Database DDBASE: Dial-Derived Domain Database CATH: Class Architecture Topology and Homologous sfily PALI: Phylogeny and ALIgnment of homologous protein structures MODBASE: A Database of Annotated Comparative Protein Structure Models 3Dee: A Database of Protein Domain Definition PQS: Protein Quaternary Structure Query Form at the EBI LPC/CSU: Ligand-Protein Contacts & Contacts of Structural LPFC: A Library of Protein Family Cores MMDB: Molecular Modelling DataBase,NCBI CE: Databases and Tools for 3-D Protein Structure Comparison and Alignment PDBSUM: Summaries and structural analyses of PDB data files Pfam: Protein families database of alignments and HMMs	Inosine monophosphate dehydrogenase (IMPDH)	Inosine monophosphate dehydrogenase (IMPDH)	Chinese hamster (Cricetulus griseus) [TaxId: 10029]	view
d1mwfa1 # Domain Specific Files ATM file: Atomic coordinates by ASTRAL ATM2ALI file: Amino acid sequences by ATM2ALI SST file: Secondary structure by SSTRUC PSA file: solvent accessibility by PSA HBD file: Hydrogen bonds by HBOND PSE file: PyMol session file for conserved interactions PDBSUM1: Topological diagram d1mwfa1 # Links to other databases and tools RCSB-PDB: Research Collaboratory for Structural Bioinformatics SCOP: Structural Classification of Proteins EBI: European Bioinformatics Institute HOMSTRAD: Homologous Structure Alignment Database DDBASE: Dial-Derived Domain Database CATH: Class Architecture Topology and Homologous sfily PALI: Phylogeny and ALIgnment of homologous protein structures MODBASE: A Database of Annotated Comparative Protein Structure Models 3Dee: A Database of Protein Domain Definition PQS: Protein Quaternary Structure Query Form at the EBI LPC/CSU: Ligand-Protein Contacts & Contacts of Structural LPFC: A Library of Protein Family Cores MMDB: Molecular Modelling DataBase,NCBI CE: Databases and Tools for 3-D Protein Structure Comparison and Alignment PDBSUM: Summaries and structural analyses of PDB data files Pfam: Protein families database of alignments and HMMs	Inosine monophosphate dehydrogenase (IMPDH)	Inosine monophosphate dehydrogenase (IMPDH)	Tritrichomonas foetus [TaxId: 5724]	view
d2c6qa1 # Domain Specific Files ATM file: Atomic coordinates by ASTRAL ATM2ALI file: Amino acid sequences by ATM2ALI SST file: Secondary structure by SSTRUC PSA file: solvent accessibility by PSA HBD file: Hydrogen bonds by HBOND PSE file: PyMol session file for conserved interactions PDBSUM1: Topological diagram d2c6qa1 # Links to other databases and tools RCSB-PDB: Research Collaboratory for Structural Bioinformatics SCOP: Structural Classification of Proteins EBI: European Bioinformatics Institute HOMSTRAD: Homologous Structure Alignment Database DDBASE: Dial-Derived Domain Database CATH: Class Architecture Topology and Homologous sfily PALI: Phylogeny and ALIgnment of homologous protein structures MODBASE: A Database of Annotated Comparative Protein Structure Models 3Dee: A Database of Protein Domain Definition PQS: Protein Quaternary Structure Query Form at the EBI LPC/CSU: Ligand-Protein Contacts & Contacts of Structural LPFC: A Library of Protein Family Cores MMDB: Molecular Modelling DataBase,NCBI CE: Databases and Tools for 3-D Protein Structure Comparison and Alignment PDBSUM: Summaries and structural analyses of PDB data files Pfam: Protein families database of alignments and HMMs	automated matches	automated matches	Human (Homo sapiens) [TaxId: 9606]	view
d6d4ra- # Domain Specific Files ATM file: Atomic coordinates by ASTRAL ATM2ALI file: Amino acid sequences by ATM2ALI SST file: Secondary structure by SSTRUC PSA file: solvent accessibility by PSA HBD file: Hydrogen bonds by HBOND PSE file: PyMol session file for conserved interactions PDBSUM1: Topological diagram d6d4ra- # Links to other databases and tools RCSB-PDB: Research Collaboratory for Structural Bioinformatics SCOP: Structural Classification of Proteins EBI: European Bioinformatics Institute HOMSTRAD: Homologous Structure Alignment Database DDBASE: Dial-Derived Domain Database CATH: Class Architecture Topology and Homologous sfily PALI: Phylogeny and ALIgnment of homologous protein structures MODBASE: A Database of Annotated Comparative Protein Structure Models 3Dee: A Database of Protein Domain Definition PQS: Protein Quaternary Structure Query Form at the EBI LPC/CSU: Ligand-Protein Contacts & Contacts of Structural LPFC: A Library of Protein Family Cores MMDB: Molecular Modelling DataBase,NCBI CE: Databases and Tools for 3-D Protein Structure Comparison and Alignment PDBSUM: Summaries and structural analyses of PDB data files Pfam: Protein families database of alignments and HMMs	automated matches	automated matches	Mycobacterium thermoresistibile [TaxId: 1078020]	view

No outliers

Feature	Download
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

									10										20										30										40										50										60										70										80										90										100										110										120										130										140										150										160										170										180										190										200										210										220										230										240										250										260										270										280										290										300										310										320										330										340										350										360										370										380										390										400										410
-	-	-	-	-	S	Y	V	P	D	D	G	L	T	A	Q	Q	L	F	N	C	-	-	-	-	-	-	-	G	D	G	L	T	Y	N	D	F	L	I	L	P	G	Y	I	-	-	D	F	T	A	D	Q	V	D	L	T	S	A	L	T	K	-	-	-	-	-	-	-	K	I	T	L	K	T	P	L	V	S	S	P	M	D	T	V	T	E	A	G	M	A	I	A	M	A	L	T	G	G	I	G	F	I	H	H	N	C	T	P	E	F	Q	A	N	E	V	R	K	V	K	K	Y	E	Q	Y	P	L	A	S	K	D	A	K	K	Q	L	L	C	G	A	A	I	G	T	H	E	D	D	K	Y	R	L	D	L	L	A	L	A	G	-	-	V	D	V	V	V	L	D	S	S	Q	G	N	S	I	F	Q	I	N	M	I	K	Y	M	K	E	K	Y	P	-	N	L	Q	V	I	G	G	N	V	V	T	A	A	Q	A	K	N	L	I	D	A	G	V	D	A	L	R	V	G	M	G	C	G	S	I	-	I	T	Q	E	V	L	A	C	G	R	P	Q	A	T	A	V	Y	K	V	S	E	Y	A	R	R	F	-	-	-	-	-	-	G	V	P	V	I	A	D	G	G	I	Q	N	V	G	H	I	A	K	A	L	A	L	G	A	S	T	V	M	M	G	S	L	L	A	A	T	T	E	A	P	G	E	Y	F	F	S	D	G	I	R	L	K	K	Y	R	G	M	G	S	L	D	A	M	I	-	-	-	-	-	-	-	-	-	-	-	-	K	V	A	Q	G	V	S	G	A	V	Q	D	K	G	S	I	H	K	F	V	P	Y	L	I	A	G	I	Q	H	S	C	Q	D	I	G	A	K	S	L	T	Q	V	R	A	M	M	Y	S	G	E	L	K	F	E	K	R	T	S	S	A	Q	V	E	G	G	V	H	S	L	H	S	Y	E	K	R	L	F
A	K	Y	Y	N	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	E	P	C	H	T	F	N	E	Y	L	L	I	P	G	L	S	T	V	D	C	I	P	S	N	V	N	L	S	T	P	L	V	K	F	Q	K	G	Q	Q	S	E	I	N	L	K	I	P	L	V	S	A	I	M	Q	S	V	S	G	E	K	M	A	I	A	L	A	R	E	G	G	I	S	F	I	F	G	S	Q	S	I	E	S	Q	A	A	M	V	H	A	V	K	N	F	-	-	-	-	-	-	-	-	-	-	-	-	R	Y	L	V	G	A	G	I	N	T	-	R	D	F	R	E	R	V	P	A	L	V	E	A	G	-	-	A	D	V	L	C	I	D	S	S	D	G	F	S	E	W	Q	K	I	T	I	G	W	I	R	D	K	Y	G	D	K	V	K	V	G	A	G	N	I	V	D	G	E	G	F	R	Y	L	A	D	A	G	A	D	F	I	K	I	G	I	G	G	G	S	I	C	I	T	R	E	Q	K	G	I	G	R	G	Q	A	T	A	V	I	D	V	V	A	E	R	N	K	Y	F	E	E	T	G	I	Y	I	P	V	C	S	D	G	G	I	V	Y	D	Y	H	M	T	L	A	L	A	M	G	A	D	F	I	M	L	G	R	Y	F	A	R	F	E	E	S	P	T	R	K	V	T	I	N	G	S	V	M	K	E	Y	W	G	E	G	S	S	R	A	R	N	W	Q	R	Y	D	L	G	G	K	Q	K	L	S	F	E	E	G	V	D	S	Y	V	P	Y	A	G	K	L	K	D	N	V	E	A	S	L	N	K	V	K	S	T	M	C	N	C	G	A	L	T	I	P	Q	L	Q	S	-	-	-	-	-	K	A	K	I	T	L	V	S	S	V	S	I	V	E	G	G	A	H	D	V	I	V	K	-	-	-	-	-
-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	L	D	F	K	D	V	L	L	R	P	K	R	S	T	L	K	-	S	R	S	E	V	D	L	T	R	S	F	S	-	-	F	R	N	S	K	Q	T	Y	S	G	-	V	P	I	I	A	A	N	M	D	T	V	G	T	F	E	M	A	K	V	L	C	K	F	S	L	F	T	A	V	H	K	H	Y	S	-	-	-	-	L	V	Q	W	Q	E	F	A	G	-	-	-	-	-	-	-	-	Q	N	P	D	C	L	E	H	L	A	A	S	S	G	T	G	S	S	D	F	E	Q	L	E	Q	I	L	E	A	I	P	Q	V	K	Y	I	C	L	D	V	A	N	G	Y	S	E	H	F	V	E	F	V	K	D	V	R	K	R	F	P	-	Q	H	T	I	M	A	G	N	V	V	T	G	E	M	V	E	E	L	I	L	S	G	A	D	I	I	K	V	G	I	G	P	G	S	V	C	T	T	R	K	K	T	G	V	G	Y	P	Q	L	S	A	V	M	E	C	A	D	A	A	H	G	L	-	-	-	-	-	-	K	G	H	I	I	S	D	G	G	C	S	C	P	G	D	V	A	K	A	F	G	A	G	A	D	F	V	M	L	G	G	M	L	A	G	H	S	E	S	G	G	E	L	I	E	R	D	G	K	K	Y	K	L	F	Y	G	M	S	S	E	M	A	M	K	K	Y	A	G	G	V	A	E	-	-	-	Y	R	A	S	E	G	K	T	V	E	V	P	F	K	G	D	V	E	H	T	I	R	D	I	L	G	G	I	R	S	T	C	T	Y	V	G	A	A	K	L	K	E	L	S	R	-	-	-	-	-	R	T	T	F	I	R	V	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	V	P	T	G	G	D	D	P	T	K	I	A	M	L	G	L	T	F	D	D	V	L	L	L	P	A	A	S	-	-	D	V	L	P	A	N	A	D	T	S	S	Q	L	T	K	-	-	-	-	-	-	-	K	I	R	L	K	V	P	L	V	S	S	A	M	D	T	V	T	E	A	R	M	A	I	A	M	A	R	A	G	G	M	G	V	L	H	R	N	L	P	V	A	E	Q	A	A	Q	V	E	T	V	K	R	S	G	-	-	-	-	-	-	-	-	-	-	-	G	L	L	V	G	A	A	V	G	V	G	D	D	A	W	E	R	A	M	A	L	R	D	A	G	-	-	V	D	V	L	V	V	D	T	A	H	A	H	N	-	-	V	L	D	M	V	H	R	L	K	T	T	V	G	-	D	I	E	V	V	G	G	N	V	A	T	R	A	A	A	A	A	L	V	E	A	G	A	D	A	V	K	V	G	V	G	P	G	S	I	C	T	T	R	V	V	A	G	V	G	A	P	Q	I	T	A	I	L	E	A	V	A	A	C	A	P	H	-	-	-	-	-	-	G	V	P	V	I	A	D	G	G	L	Q	Y	S	G	D	I	A	K	A	L	A	A	G	A	S	T	A	M	L	G	S	L	L	A	G	T	A	E	S	P	G	E	L	I	L	V	G	-	-	Q	F	K	S	Y	R	G	M	G	S	L	G	A	M	L	-	-	-	-	-	-	-	-	-	-	-	-	-	V	P	E	G	I	E	G	R	V	P	F	-	G	P	L	S	T	V	I	H	Q	L	V	G	G	L	R	A	A	M	G	Y	T	G	S	A	T	I	E	E	L	Q	Q	-	-	-	-	-	-	A	Q	F	V	Q	I	T	A	A	G	L	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-

Member	Chain	UniProtKB	GO term
d1jr1b1	B	P12269	GO:0000166
d1jr1b1	B	P12269	GO:0000166
d1jr1b1	B	P12269	GO:0003824
d1jr1b1	B	P12269	GO:0003824
d1jr1b1	B	P12269	GO:0003938
d1jr1b1	B	P12269	GO:0003938
d1jr1b1	B	P12269	GO:0005634
d1jr1b1	B	P12269	GO:0005634
d1jr1b1	B	P12269	GO:0005737
d1jr1b1	B	P12269	GO:0005737
d1jr1b1	B	P12269	GO:0005829
d1jr1b1	B	P12269	GO:0005829
d1jr1b1	B	P12269	GO:0006164
d1jr1b1	B	P12269	GO:0006164
d1jr1b1	B	P12269	GO:0006177
d1jr1b1	B	P12269	GO:0006177
d1jr1b1	B	P12269	GO:0006183
d1jr1b1	B	P12269	GO:0006183
d1jr1b1	B	P12269	GO:0007623
d1jr1b1	B	P12269	GO:0007623
d1jr1b1	B	P12269	GO:0016491
d1jr1b1	B	P12269	GO:0016491
d1jr1b1	B	P12269	GO:0046651
d1jr1b1	B	P12269	GO:0046651
d1jr1b1	B	P12269	GO:0046872
d1jr1b1	B	P12269	GO:0046872
d1jr1b1	B	P12269	GO:0071353
d1jr1b1	B	P12269	GO:0071353
d1jr1b1	B	P12269	GO:0097294
d1jr1b1	B	P12269	GO:0097294

									10										20										30										40										50										60										70										80										90										100										110										120										130										140										150										160										170										180										190										200										210										220										230										240										250										260										270										280										290										300										310										320										330										340										350										360										370										380										390										400										410
-	-	-	-	-	S	Y	V	P	D	D	G	L	T	A	Q	Q	L	F	N	C	-	-	-	-	-	-	-	G	D	G	L	T	Y	N	D	F	L	I	L	P	G	Y	I	-	-	D	F	T	A	D	Q	V	D	L	T	S	A	L	T	K	-	-	-	-	-	-	-	K	I	T	L	K	T	P	L	V	S	S	P	M	D	T	V	T	E	A	G	M	A	I	A	M	A	L	T	G	G	I	G	F	I	H	H	N	C	T	P	E	F	Q	A	N	E	V	R	K	V	K	K	Y	E	Q	Y	P	L	A	S	K	D	A	K	K	Q	L	L	C	G	A	A	I	G	T	H	E	D	D	K	Y	R	L	D	L	L	A	L	A	G	-	-	V	D	V	V	V	L	D	S	S	Q	G	N	S	I	F	Q	I	N	M	I	K	Y	M	K	E	K	Y	P	-	N	L	Q	V	I	G	G	N	V	V	T	A	A	Q	A	K	N	L	I	D	A	G	V	D	A	L	R	V	G	M	G	C	G	S	I	-	I	T	Q	E	V	L	A	C	G	R	P	Q	A	T	A	V	Y	K	V	S	E	Y	A	R	R	F	-	-	-	-	-	-	G	V	P	V	I	A	D	G	G	I	Q	N	V	G	H	I	A	K	A	L	A	L	G	A	S	T	V	M	M	G	S	L	L	A	A	T	T	E	A	P	G	E	Y	F	F	S	D	G	I	R	L	K	K	Y	R	G	M	G	S	L	D	A	M	I	-	-	-	-	-	-	-	-	-	-	-	-	K	V	A	Q	G	V	S	G	A	V	Q	D	K	G	S	I	H	K	F	V	P	Y	L	I	A	G	I	Q	H	S	C	Q	D	I	G	A	K	S	L	T	Q	V	R	A	M	M	Y	S	G	E	L	K	F	E	K	R	T	S	S	A	Q	V	E	G	G	V	H	S	L	H	S	Y	E	K	R	L	F
A	K	Y	Y	N	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	E	P	C	H	T	F	N	E	Y	L	L	I	P	G	L	S	T	V	D	C	I	P	S	N	V	N	L	S	T	P	L	V	K	F	Q	K	G	Q	Q	S	E	I	N	L	K	I	P	L	V	S	A	I	M	Q	S	V	S	G	E	K	M	A	I	A	L	A	R	E	G	G	I	S	F	I	F	G	S	Q	S	I	E	S	Q	A	A	M	V	H	A	V	K	N	F	-	-	-	-	-	-	-	-	-	-	-	-	R	Y	L	V	G	A	G	I	N	T	-	R	D	F	R	E	R	V	P	A	L	V	E	A	G	-	-	A	D	V	L	C	I	D	S	S	D	G	F	S	E	W	Q	K	I	T	I	G	W	I	R	D	K	Y	G	D	K	V	K	V	G	A	G	N	I	V	D	G	E	G	F	R	Y	L	A	D	A	G	A	D	F	I	K	I	G	I	G	G	G	S	I	C	I	T	R	E	Q	K	G	I	G	R	G	Q	A	T	A	V	I	D	V	V	A	E	R	N	K	Y	F	E	E	T	G	I	Y	I	P	V	C	S	D	G	G	I	V	Y	D	Y	H	M	T	L	A	L	A	M	G	A	D	F	I	M	L	G	R	Y	F	A	R	F	E	E	S	P	T	R	K	V	T	I	N	G	S	V	M	K	E	Y	W	G	E	G	S	S	R	A	R	N	W	Q	R	Y	D	L	G	G	K	Q	K	L	S	F	E	E	G	V	D	S	Y	V	P	Y	A	G	K	L	K	D	N	V	E	A	S	L	N	K	V	K	S	T	M	C	N	C	G	A	L	T	I	P	Q	L	Q	S	-	-	-	-	-	K	A	K	I	T	L	V	S	S	V	S	I	V	E	G	G	A	H	D	V	I	V	K	-	-	-	-	-
-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	L	D	F	K	D	V	L	L	R	P	K	R	S	T	L	K	-	S	R	S	E	V	D	L	T	R	S	F	S	-	-	F	R	N	S	K	Q	T	Y	S	G	-	V	P	I	I	A	A	N	M	D	T	V	G	T	F	E	M	A	K	V	L	C	K	F	S	L	F	T	A	V	H	K	H	Y	S	-	-	-	-	L	V	Q	W	Q	E	F	A	G	-	-	-	-	-	-	-	-	Q	N	P	D	C	L	E	H	L	A	A	S	S	G	T	G	S	S	D	F	E	Q	L	E	Q	I	L	E	A	I	P	Q	V	K	Y	I	C	L	D	V	A	N	G	Y	S	E	H	F	V	E	F	V	K	D	V	R	K	R	F	P	-	Q	H	T	I	M	A	G	N	V	V	T	G	E	M	V	E	E	L	I	L	S	G	A	D	I	I	K	V	G	I	G	P	G	S	V	C	T	T	R	K	K	T	G	V	G	Y	P	Q	L	S	A	V	M	E	C	A	D	A	A	H	G	L	-	-	-	-	-	-	K	G	H	I	I	S	D	G	G	C	S	C	P	G	D	V	A	K	A	F	G	A	G	A	D	F	V	M	L	G	G	M	L	A	G	H	S	E	S	G	G	E	L	I	E	R	D	G	K	K	Y	K	L	F	Y	G	M	S	S	E	M	A	M	K	K	Y	A	G	G	V	A	E	-	-	-	Y	R	A	S	E	G	K	T	V	E	V	P	F	K	G	D	V	E	H	T	I	R	D	I	L	G	G	I	R	S	T	C	T	Y	V	G	A	A	K	L	K	E	L	S	R	-	-	-	-	-	R	T	T	F	I	R	V	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	V	P	T	G	G	D	D	P	T	K	I	A	M	L	G	L	T	F	D	D	V	L	L	L	P	A	A	S	-	-	D	V	L	P	A	N	A	D	T	S	S	Q	L	T	K	-	-	-	-	-	-	-	K	I	R	L	K	V	P	L	V	S	S	A	M	D	T	V	T	E	A	R	M	A	I	A	M	A	R	A	G	G	M	G	V	L	H	R	N	L	P	V	A	E	Q	A	A	Q	V	E	T	V	K	R	S	G	-	-	-	-	-	-	-	-	-	-	-	G	L	L	V	G	A	A	V	G	V	G	D	D	A	W	E	R	A	M	A	L	R	D	A	G	-	-	V	D	V	L	V	V	D	T	A	H	A	H	N	-	-	V	L	D	M	V	H	R	L	K	T	T	V	G	-	D	I	E	V	V	G	G	N	V	A	T	R	A	A	A	A	A	L	V	E	A	G	A	D	A	V	K	V	G	V	G	P	G	S	I	C	T	T	R	V	V	A	G	V	G	A	P	Q	I	T	A	I	L	E	A	V	A	A	C	A	P	H	-	-	-	-	-	-	G	V	P	V	I	A	D	G	G	L	Q	Y	S	G	D	I	A	K	A	L	A	A	G	A	S	T	A	M	L	G	S	L	L	A	G	T	A	E	S	P	G	E	L	I	L	V	G	-	-	Q	F	K	S	Y	R	G	M	G	S	L	G	A	M	L	-	-	-	-	-	-	-	-	-	-	-	-	-	V	P	E	G	I	E	G	R	V	P	F	-	G	P	L	S	T	V	I	H	Q	L	V	G	G	L	R	A	A	M	G	Y	T	G	S	A	T	I	E	E	L	Q	Q	-	-	-	-	-	-	A	Q	F	V	Q	I	T	A	A	G	L	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-

									10										20										30										40										50										60										70										80										90										100										110										120										130										140										150										160										170										180										190										200										210										220										230										240										250										260										270										280										290										300										310										320										330										340										350										360										370										380										390										400										410
-	-	-	-	-	S	Y	V	P	D	D	G	L	T	A	Q	Q	L	F	N	C	-	-	-	-	-	-	-	G	D	G	L	T	Y	N	D	F	L	I	L	P	G	Y	I	-	-	D	F	T	A	D	Q	V	D	L	T	S	A	L	T	K	-	-	-	-	-	-	-	K	I	T	L	K	T	P	L	V	S	S	P	M	D	T	V	T	E	A	G	M	A	I	A	M	A	L	T	G	G	I	G	F	I	H	H	N	C	T	P	E	F	Q	A	N	E	V	R	K	V	K	K	Y	E	Q	Y	P	L	A	S	K	D	A	K	K	Q	L	L	C	G	A	A	I	G	T	H	E	D	D	K	Y	R	L	D	L	L	A	L	A	G	-	-	V	D	V	V	V	L	D	S	S	Q	G	N	S	I	F	Q	I	N	M	I	K	Y	M	K	E	K	Y	P	-	N	L	Q	V	I	G	G	N	V	V	T	A	A	Q	A	K	N	L	I	D	A	G	V	D	A	L	R	V	G	M	G	C	G	S	I	-	I	T	Q	E	V	L	A	C	G	R	P	Q	A	T	A	V	Y	K	V	S	E	Y	A	R	R	F	-	-	-	-	-	-	G	V	P	V	I	A	D	G	G	I	Q	N	V	G	H	I	A	K	A	L	A	L	G	A	S	T	V	M	M	G	S	L	L	A	A	T	T	E	A	P	G	E	Y	F	F	S	D	G	I	R	L	K	K	Y	R	G	M	G	S	L	D	A	M	I	-	-	-	-	-	-	-	-	-	-	-	-	K	V	A	Q	G	V	S	G	A	V	Q	D	K	G	S	I	H	K	F	V	P	Y	L	I	A	G	I	Q	H	S	C	Q	D	I	G	A	K	S	L	T	Q	V	R	A	M	M	Y	S	G	E	L	K	F	E	K	R	T	S	S	A	Q	V	E	G	G	V	H	S	L	H	S	Y	E	K	R	L	F
A	K	Y	Y	N	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	E	P	C	H	T	F	N	E	Y	L	L	I	P	G	L	S	T	V	D	C	I	P	S	N	V	N	L	S	T	P	L	V	K	F	Q	K	G	Q	Q	S	E	I	N	L	K	I	P	L	V	S	A	I	M	Q	S	V	S	G	E	K	M	A	I	A	L	A	R	E	G	G	I	S	F	I	F	G	S	Q	S	I	E	S	Q	A	A	M	V	H	A	V	K	N	F	-	-	-	-	-	-	-	-	-	-	-	-	R	Y	L	V	G	A	G	I	N	T	-	R	D	F	R	E	R	V	P	A	L	V	E	A	G	-	-	A	D	V	L	C	I	D	S	S	D	G	F	S	E	W	Q	K	I	T	I	G	W	I	R	D	K	Y	G	D	K	V	K	V	G	A	G	N	I	V	D	G	E	G	F	R	Y	L	A	D	A	G	A	D	F	I	K	I	G	I	G	G	G	S	I	C	I	T	R	E	Q	K	G	I	G	R	G	Q	A	T	A	V	I	D	V	V	A	E	R	N	K	Y	F	E	E	T	G	I	Y	I	P	V	C	S	D	G	G	I	V	Y	D	Y	H	M	T	L	A	L	A	M	G	A	D	F	I	M	L	G	R	Y	F	A	R	F	E	E	S	P	T	R	K	V	T	I	N	G	S	V	M	K	E	Y	W	G	E	G	S	S	R	A	R	N	W	Q	R	Y	D	L	G	G	K	Q	K	L	S	F	E	E	G	V	D	S	Y	V	P	Y	A	G	K	L	K	D	N	V	E	A	S	L	N	K	V	K	S	T	M	C	N	C	G	A	L	T	I	P	Q	L	Q	S	-	-	-	-	-	K	A	K	I	T	L	V	S	S	V	S	I	V	E	G	G	A	H	D	V	I	V	K	-	-	-	-	-
-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	L	D	F	K	D	V	L	L	R	P	K	R	S	T	L	K	-	S	R	S	E	V	D	L	T	R	S	F	S	-	-	F	R	N	S	K	Q	T	Y	S	G	-	V	P	I	I	A	A	N	M	D	T	V	G	T	F	E	M	A	K	V	L	C	K	F	S	L	F	T	A	V	H	K	H	Y	S	-	-	-	-	L	V	Q	W	Q	E	F	A	G	-	-	-	-	-	-	-	-	Q	N	P	D	C	L	E	H	L	A	A	S	S	G	T	G	S	S	D	F	E	Q	L	E	Q	I	L	E	A	I	P	Q	V	K	Y	I	C	L	D	V	A	N	G	Y	S	E	H	F	V	E	F	V	K	D	V	R	K	R	F	P	-	Q	H	T	I	M	A	G	N	V	V	T	G	E	M	V	E	E	L	I	L	S	G	A	D	I	I	K	V	G	I	G	P	G	S	V	C	T	T	R	K	K	T	G	V	G	Y	P	Q	L	S	A	V	M	E	C	A	D	A	A	H	G	L	-	-	-	-	-	-	K	G	H	I	I	S	D	G	G	C	S	C	P	G	D	V	A	K	A	F	G	A	G	A	D	F	V	M	L	G	G	M	L	A	G	H	S	E	S	G	G	E	L	I	E	R	D	G	K	K	Y	K	L	F	Y	G	M	S	S	E	M	A	M	K	K	Y	A	G	G	V	A	E	-	-	-	Y	R	A	S	E	G	K	T	V	E	V	P	F	K	G	D	V	E	H	T	I	R	D	I	L	G	G	I	R	S	T	C	T	Y	V	G	A	A	K	L	K	E	L	S	R	-	-	-	-	-	R	T	T	F	I	R	V	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	V	P	T	G	G	D	D	P	T	K	I	A	M	L	G	L	T	F	D	D	V	L	L	L	P	A	A	S	-	-	D	V	L	P	A	N	A	D	T	S	S	Q	L	T	K	-	-	-	-	-	-	-	K	I	R	L	K	V	P	L	V	S	S	A	M	D	T	V	T	E	A	R	M	A	I	A	M	A	R	A	G	G	M	G	V	L	H	R	N	L	P	V	A	E	Q	A	A	Q	V	E	T	V	K	R	S	G	-	-	-	-	-	-	-	-	-	-	-	G	L	L	V	G	A	A	V	G	V	G	D	D	A	W	E	R	A	M	A	L	R	D	A	G	-	-	V	D	V	L	V	V	D	T	A	H	A	H	N	-	-	V	L	D	M	V	H	R	L	K	T	T	V	G	-	D	I	E	V	V	G	G	N	V	A	T	R	A	A	A	A	A	L	V	E	A	G	A	D	A	V	K	V	G	V	G	P	G	S	I	C	T	T	R	V	V	A	G	V	G	A	P	Q	I	T	A	I	L	E	A	V	A	A	C	A	P	H	-	-	-	-	-	-	G	V	P	V	I	A	D	G	G	L	Q	Y	S	G	D	I	A	K	A	L	A	A	G	A	S	T	A	M	L	G	S	L	L	A	G	T	A	E	S	P	G	E	L	I	L	V	G	-	-	Q	F	K	S	Y	R	G	M	G	S	L	G	A	M	L	-	-	-	-	-	-	-	-	-	-	-	-	-	V	P	E	G	I	E	G	R	V	P	F	-	G	P	L	S	T	V	I	H	Q	L	V	G	G	L	R	A	A	M	G	Y	T	G	S	A	T	I	E	E	L	Q	Q	-	-	-	-	-	-	A	Q	F	V	Q	I	T	A	A	G	L	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-

									10										20										30										40										50										60										70										80										90										100										110										120										130										140										150										160										170										180										190										200										210										220										230										240										250										260										270										280										290										300										310										320										330										340										350										360										370										380										390										400										410
-	-	-	-	-	S	Y	V	P	D	D	G	L	T	A	Q	Q	L	F	N	C	-	-	-	-	-	-	-	G	D	G	L	T	Y	N	D	F	L	I	L	P	G	Y	I	-	-	D	F	T	A	D	Q	V	D	L	T	S	A	L	T	K	-	-	-	-	-	-	-	K	I	T	L	K	T	P	L	V	S	S	P	M	D	T	V	T	E	A	G	M	A	I	A	M	A	L	T	G	G	I	G	F	I	H	H	N	C	T	P	E	F	Q	A	N	E	V	R	K	V	K	K	Y	E	Q	Y	P	L	A	S	K	D	A	K	K	Q	L	L	C	G	A	A	I	G	T	H	E	D	D	K	Y	R	L	D	L	L	A	L	A	G	-	-	V	D	V	V	V	L	D	S	S	Q	G	N	S	I	F	Q	I	N	M	I	K	Y	M	K	E	K	Y	P	-	N	L	Q	V	I	G	G	N	V	V	T	A	A	Q	A	K	N	L	I	D	A	G	V	D	A	L	R	V	G	M	G	C	G	S	I	-	I	T	Q	E	V	L	A	C	G	R	P	Q	A	T	A	V	Y	K	V	S	E	Y	A	R	R	F	-	-	-	-	-	-	G	V	P	V	I	A	D	G	G	I	Q	N	V	G	H	I	A	K	A	L	A	L	G	A	S	T	V	M	M	G	S	L	L	A	A	T	T	E	A	P	G	E	Y	F	F	S	D	G	I	R	L	K	K	Y	R	G	M	G	S	L	D	A	M	I	-	-	-	-	-	-	-	-	-	-	-	-	K	V	A	Q	G	V	S	G	A	V	Q	D	K	G	S	I	H	K	F	V	P	Y	L	I	A	G	I	Q	H	S	C	Q	D	I	G	A	K	S	L	T	Q	V	R	A	M	M	Y	S	G	E	L	K	F	E	K	R	T	S	S	A	Q	V	E	G	G	V	H	S	L	H	S	Y	E	K	R	L	F
A	K	Y	Y	N	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	E	P	C	H	T	F	N	E	Y	L	L	I	P	G	L	S	T	V	D	C	I	P	S	N	V	N	L	S	T	P	L	V	K	F	Q	K	G	Q	Q	S	E	I	N	L	K	I	P	L	V	S	A	I	M	Q	S	V	S	G	E	K	M	A	I	A	L	A	R	E	G	G	I	S	F	I	F	G	S	Q	S	I	E	S	Q	A	A	M	V	H	A	V	K	N	F	-	-	-	-	-	-	-	-	-	-	-	-	R	Y	L	V	G	A	G	I	N	T	-	R	D	F	R	E	R	V	P	A	L	V	E	A	G	-	-	A	D	V	L	C	I	D	S	S	D	G	F	S	E	W	Q	K	I	T	I	G	W	I	R	D	K	Y	G	D	K	V	K	V	G	A	G	N	I	V	D	G	E	G	F	R	Y	L	A	D	A	G	A	D	F	I	K	I	G	I	G	G	G	S	I	C	I	T	R	E	Q	K	G	I	G	R	G	Q	A	T	A	V	I	D	V	V	A	E	R	N	K	Y	F	E	E	T	G	I	Y	I	P	V	C	S	D	G	G	I	V	Y	D	Y	H	M	T	L	A	L	A	M	G	A	D	F	I	M	L	G	R	Y	F	A	R	F	E	E	S	P	T	R	K	V	T	I	N	G	S	V	M	K	E	Y	W	G	E	G	S	S	R	A	R	N	W	Q	R	Y	D	L	G	G	K	Q	K	L	S	F	E	E	G	V	D	S	Y	V	P	Y	A	G	K	L	K	D	N	V	E	A	S	L	N	K	V	K	S	T	M	C	N	C	G	A	L	T	I	P	Q	L	Q	S	-	-	-	-	-	K	A	K	I	T	L	V	S	S	V	S	I	V	E	G	G	A	H	D	V	I	V	K	-	-	-	-	-
-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	L	D	F	K	D	V	L	L	R	P	K	R	S	T	L	K	-	S	R	S	E	V	D	L	T	R	S	F	S	-	-	F	R	N	S	K	Q	T	Y	S	G	-	V	P	I	I	A	A	N	M	D	T	V	G	T	F	E	M	A	K	V	L	C	K	F	S	L	F	T	A	V	H	K	H	Y	S	-	-	-	-	L	V	Q	W	Q	E	F	A	G	-	-	-	-	-	-	-	-	Q	N	P	D	C	L	E	H	L	A	A	S	S	G	T	G	S	S	D	F	E	Q	L	E	Q	I	L	E	A	I	P	Q	V	K	Y	I	C	L	D	V	A	N	G	Y	S	E	H	F	V	E	F	V	K	D	V	R	K	R	F	P	-	Q	H	T	I	M	A	G	N	V	V	T	G	E	M	V	E	E	L	I	L	S	G	A	D	I	I	K	V	G	I	G	P	G	S	V	C	T	T	R	K	K	T	G	V	G	Y	P	Q	L	S	A	V	M	E	C	A	D	A	A	H	G	L	-	-	-	-	-	-	K	G	H	I	I	S	D	G	G	C	S	C	P	G	D	V	A	K	A	F	G	A	G	A	D	F	V	M	L	G	G	M	L	A	G	H	S	E	S	G	G	E	L	I	E	R	D	G	K	K	Y	K	L	F	Y	G	M	S	S	E	M	A	M	K	K	Y	A	G	G	V	A	E	-	-	-	Y	R	A	S	E	G	K	T	V	E	V	P	F	K	G	D	V	E	H	T	I	R	D	I	L	G	G	I	R	S	T	C	T	Y	V	G	A	A	K	L	K	E	L	S	R	-	-	-	-	-	R	T	T	F	I	R	V	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	V	P	T	G	G	D	D	P	T	K	I	A	M	L	G	L	T	F	D	D	V	L	L	L	P	A	A	S	-	-	D	V	L	P	A	N	A	D	T	S	S	Q	L	T	K	-	-	-	-	-	-	-	K	I	R	L	K	V	P	L	V	S	S	A	M	D	T	V	T	E	A	R	M	A	I	A	M	A	R	A	G	G	M	G	V	L	H	R	N	L	P	V	A	E	Q	A	A	Q	V	E	T	V	K	R	S	G	-	-	-	-	-	-	-	-	-	-	-	G	L	L	V	G	A	A	V	G	V	G	D	D	A	W	E	R	A	M	A	L	R	D	A	G	-	-	V	D	V	L	V	V	D	T	A	H	A	H	N	-	-	V	L	D	M	V	H	R	L	K	T	T	V	G	-	D	I	E	V	V	G	G	N	V	A	T	R	A	A	A	A	A	L	V	E	A	G	A	D	A	V	K	V	G	V	G	P	G	S	I	C	T	T	R	V	V	A	G	V	G	A	P	Q	I	T	A	I	L	E	A	V	A	A	C	A	P	H	-	-	-	-	-	-	G	V	P	V	I	A	D	G	G	L	Q	Y	S	G	D	I	A	K	A	L	A	A	G	A	S	T	A	M	L	G	S	L	L	A	G	T	A	E	S	P	G	E	L	I	L	V	G	-	-	Q	F	K	S	Y	R	G	M	G	S	L	G	A	M	L	-	-	-	-	-	-	-	-	-	-	-	-	-	V	P	E	G	I	E	G	R	V	P	F	-	G	P	L	S	T	V	I	H	Q	L	V	G	G	L	R	A	A	M	G	Y	T	G	S	A	T	I	E	E	L	Q	Q	-	-	-	-	-	-	A	Q	F	V	Q	I	T	A	A	G	L	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-