Superfamily : 50923 [ Hemopexin-like domain ]
Class : All beta proteins
Fold : 4-bladed beta-propeller
# of Members : 7
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1hxna-  ( 226 )            strçdpdlvLsAMVsDnhgATYVFsgshYWrldtd-----gw
d1itva-  (   1 )            ddAçnvn-iFdAIAeig-nqLyLFkdgkyWrFsegrgsrPq-
d1qhua1  (  24 )            ieqÇsdgwsFdATTlDdngtmLFFkdefVWksh-----rGi-
d1rtga-  ( 458 )    tptlgpvtpeiçkqdIvFdGIAqIr-geIFFFkdrFIWrTvt-prdkPm-
d1su3a2  ( 271 )        gpqtpkAcdskLtFdAITtir-gevMFFkdrFYMrtnp-fypeVe-
d3c7xa-  ( 316 )            pnIçd--GnFdTVAmLr-gemFVFkerwFWrVr--nnqvmdg
d6o5ea-  ( 153 )            melçs-gkpFdAFtDlkngslfAFrgqySYeldekavrpGy-
                                       bbbb    bbbbbb  bbbb           

                             60        70        80        90        100 
d1hxna-  ( 265 )    hswpIahqWpqGPstVdAAFswe---dkLYLIqdtkVyVFlTkggytlvn
d1itva-  (  40 )    GpflIadkWpaLprkLdSVfeEpl-skklFFFsgrqVWVYtg---asvl-
d1qhua1  (  60 )    -relIserWknFigpVdAAFrhg--htsVyLIkgdkVwvyt---------
d1rtga-  ( 505 )    GpllvatfWpeLpekIdAVYeapq-eekAVFFAgneYwiYsa---stler
d1su3a2  ( 314 )    -lnfisvfWpqLpngLeAAYeFad-rdEVRFFkgnkYwAVqg---qnvl-
d3c7xa-  ( 353 )    ypmpIgqfWrgLpasInTAYerkd--gkFVFFkgdkHwVFde---aslep
d6o5ea-  ( 193 )    -pklirdvW-gieGpidAAFtrinsqGktYlFkgsqYwrFed---gvldp
                     bbbaaaa         bbbb       bbbbb  bbbbbb     bb  

                             110       120       130       140       150 
d1hxna-  ( 312 )    gypkrLekeLgsPpisleaVdAAFVçp----gssrLHIMagrrLWwLdLk
d1itva-  (  85 )    -gprrLdkL--gLgadVaqVtGALrsg-----rgkmlLFSgrrLWrFdvk
d1qhua1  (  98 )    -spksLqdeFpgIp---fpLdAAVEÇhrgeÇqdeGILFFqgnrKWFWdlt
d1rtga-  ( 551 )    gypkpLtsl--gLppdvqrVdAAFNWs----knkkTyIFagdkFWrynev
d1su3a2  ( 359 )    gypkdIyssF-gFp-tvkhIdAALSee----ntGkTyFFvankYwrYDEy
d3c7xa-  ( 398 )    gypkhIkelgrgLpt--dkIDAALfwm----pngkTyFFrgnkYyrFnee
d6o5ea-  ( 238 )    dyprnisdgFdgip---dnvdAAlAlp------ervYFFkgkqyweyqf-
                       bb                bbbb         bbbbbb  bbbbbb  

                             160       170       180       190       200 
d1hxna-  ( 359 )    sgaqAtWt---elpWHe-------kVdGALÇmekpLgpnsçstsgpNLYL
d1itva-  ( 127 )    aq---mVdprsaseVdrmFpgVpldThDVFqfr------------ekaYF
d1qhua1  ( 151 )    tg---tkk---ersWp----aV-gnÇtSALrwl------------grYYÇ
d1rtga-  ( 595 )    kk---kmdpgFpklIadaWnaIpdnLdAVVDlq----------ggghSyF
d1su3a2  ( 404 )    kr---smdpgYpkmIahdFpgIghkVdAVFmk------------dgfFyF
d3c7xa-  ( 442 )    lr---aVdseYpknIk-vWegIpesPrGSFMgs----------devfTyF
d6o5ea-  ( 331 )    -------q---pqfisrdWhgvpgqvdAAMAgr------------iSvfF
                         bb     bb             bbbb               bbbb

                             210       220       230       240 
d1hxna-  ( 400 )    IhgpnLyçYvdkLnaak-----nlppqrVsr-lLgÇth     
d1itva-  ( 162 )    CqdrfYwrVssrselnqvd-----qvgyvtydiLqÇp----ed
d1qhua1  ( 178 )    FqgnqFlrFnpv--sGevpp---gypldVrdyfLsÇpgrghrs
d1rtga-  ( 632 )    FkgayYlkLeNq--slksv-----kfgsiksdWLgç       
d1su3a2  ( 439 )    FhgtrQykFdpk--tkril-----tlqkAns-wFn        
d3c7xa-  ( 478 )    YkgnkywkFnnq--klkvep---gypksAlrdwMgçp----sg
d6o5ea-  ( 439 )    FsgdkYyrvnlr--trrvdtvdppYprsiaqywlgçpa     
                    bb  bbbbbb       b        bbaaa
 

 

Domain IDNameFamilySourceDomainSTRING-DB
HemopexinHemopexin-like domainRabbit (Oryctolagus cuniculus) [TaxId: 9986]view
Gelatinase B (MMP-9)Hemopexin-like domainHuman (Homo sapiens) [TaxId: 9606]view
HemopexinHemopexin-like domainRabbit (Oryctolagus cuniculus) [TaxId: 9986]view
Gelatinase A (MMP-2), C-terminal domainHemopexin-like domainHuman (Homo sapiens) [TaxId: 9606]view
Collagenase (MMP1), C-terminal domainHemopexin-like domainHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240
- - - - - - - - S T R C D P D L V L S A M V S D N H G A T Y V F S G S H Y W R L D T D - - - - - G W H S W P I A H Q W P Q G P S T V D A A F S W E - - - D K L Y L I Q D T K V Y V F L T K G G Y T L V N G Y P K R L E K E L G S P P I S L E A V D A A F V C P - - - - G S S R L H I M A G R R L W W L D L K S G A Q A T W T - - - E L P W H E - - - - - - - K V D G A L C M E K P L G P N S C S T S G P N L Y L I H G P N L Y C Y V D K L N A A K - - - - - N L P P Q R V S R - L L G C T H - - - - -
- - - - - - - - D D A C N V N - I F D A I A E I G - N Q L Y L F K D G K Y W R F S E G R G S R P Q - G P F L I A D K W P A L P R K L D S V F E E P L - S K K L F F F S G R Q V W V Y T G - - - A S V L - - G P R R L D K L - - G L G A D V A Q V T G A L R S G - - - - - R G K M L L F S G R R L W R F D V K A Q - - - M V D P R S A S E V D R M F P G V P L D T H D V F Q F R - - - - - - - - - - - - E K A Y F C Q D R F Y W R V S S R S E L N Q V D - - - - - Q V G Y V T Y D I L Q C P - - - - E D
- - - - - - - - I E Q C S D G W S F D A T T L D D N G T M L F F K D E F V W K S H - - - - - R G I - - R E L I S E R W K N F I G P V D A A F R H G - - H T S V Y L I K G D K V W V Y T - - - - - - - - - - S P K S L Q D E F P G I P - - - F P L D A A V E C H R G E C Q D E G I L F F Q G N R K W F W D L T T G - - - T K K - - - E R S W P - - - - A V - G N C T S A L R W L - - - - - - - - - - - - G R Y Y C F Q G N Q F L R F N P V - - S G E V P P - - - G Y P L D V R D Y F L S C P G R G H R S
T P T L G P V T P E I C K Q D I V F D G I A Q I R - G E I F F F K D R F I W R T V T - P R D K P M - G P L L V A T F W P E L P E K I D A V Y E A P Q - E E K A V F F A G N E Y W I Y S A - - - S T L E R G Y P K P L T S L - - G L P P D V Q R V D A A F N W S - - - - K N K K T Y I F A G D K F W R Y N E V K K - - - K M D P G F P K L I A D A W N A I P D N L D A V V D L Q - - - - - - - - - - G G G H S Y F F K G A Y Y L K L E N Q - - S L K S V - - - - - K F G S I K S D W L G C - - - - - - -
- - - - G P Q T P K A C D S K L T F D A I T T I R - G E V M F F K D R F Y M R T N P - F Y P E V E - - L N F I S V F W P Q L P N G L E A A Y E F A D - R D E V R F F K G N K Y W A V Q G - - - Q N V L - G Y P K D I Y S S F - G F P - T V K H I D A A L S E E - - - - N T G K T Y F F V A N K Y W R Y D E Y K R - - - S M D P G Y P K M I A H D F P G I G H K V D A V F M K - - - - - - - - - - - - D G F F Y F F H G T R Q Y K F D P K - - T K R I L - - - - - T L Q K A N S - W F N - - - - - - - -
- - - - - - - - P N I C D - - G N F D T V A M L R - G E M F V F K E R W F W R V R - - N N Q V M D G Y P M P I G Q F W R G L P A S I N T A Y E R K D - - G K F V F F K G D K H W V F D E - - - A S L E P G Y P K H I K E L G R G L P T - - D K I D A A L F W M - - - - P N G K T Y F F R G N K Y Y R F N E E L R - - - A V D S E Y P K N I K - V W E G I P E S P R G S F M G S - - - - - - - - - - D E V F T Y F Y K G N K Y W K F N N Q - - K L K V E P - - - G Y P K S A L R D W M G C P - - - - S G
- - - - - - - - M E L C S - G K P F D A F T D L K N G S L F A F R G Q Y S Y E L D E K A V R P G Y - - P K L I R D V W - G I E G P I D A A F T R I N S Q G K T Y L F K G S Q Y W R F E D - - - G V L D P D Y P R N I S D G F D G I P - - - D N V D A A L A L P - - - - - - E R V Y F F K G K Q Y W E Y Q F - - - - - - - - Q - - - P Q F I S R D W H G V P G Q V D A A M A G R - - - - - - - - - - - - I S V F F F S G D K Y Y R V N L R - - T R R V D T V D P P Y P R S I A Q Y W L G C P A - - - - -

 

 

 

 

 

Member Chain UniProtKB GO term
d1qhua1 A P20058 GO:0006879
d1qhua1 A P20058 GO:0015232
d1qhua1 A P20058 GO:0015886
d1su3a2 A P03956 GO:0004175
d1su3a2 A P03956 GO:0004222
d1su3a2 A P03956 GO:0004252
d1su3a2 A P03956 GO:0005576
d1su3a2 A P03956 GO:0005615
d1su3a2 A P03956 GO:0006508
d1su3a2 A P03956 GO:0008233
d1su3a2 A P03956 GO:0008237
d1su3a2 A P03956 GO:0008270
d1su3a2 A P03956 GO:0022617
d1su3a2 A P03956 GO:0030198
d1su3a2 A P03956 GO:0030574
d1su3a2 A P03956 GO:0031012
d1su3a2 A P03956 GO:0031334
d1su3a2 A P03956 GO:0046872
d1su3a2 A P03956 GO:0071492
d1su3a2 A P03956 GO:0004175
d1su3a2 A P03956 GO:0004222
d1su3a2 A P03956 GO:0004252
d1su3a2 A P03956 GO:0005576
d1su3a2 A P03956 GO:0005615
d1su3a2 A P03956 GO:0006508
d1su3a2 A P03956 GO:0008233
d1su3a2 A P03956 GO:0008237
d1su3a2 A P03956 GO:0008270
d1su3a2 A P03956 GO:0022617
d1su3a2 A P03956 GO:0030198
d1su3a2 A P03956 GO:0030574
d1su3a2 A P03956 GO:0031012
d1su3a2 A P03956 GO:0031334
d1su3a2 A P03956 GO:0046872
d1su3a2 A P03956 GO:0071492
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in