Superfamily : 50891 [ Cyclophilin-like ]
Class : All beta proteins
Fold : Cyclophilin-like
# of Members : 9
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1v9ta-  (   1 )                 agdphVlLtTs-----agnIeLeLdkqkApvSVqnFv
d1w74a-  (  12 )                 latatAtLhTn-----rgdIkIaLFgnhApkTvaNFv
d1x7fa1  ( 245 )                                 mlqLkVhFvd-------eAt-
d1zx8a1  (   2 )                     rveLlFe-----sgkCvIdLnee--yeVVklLk
d2b71a1  (  23 )    leekiayykmkGhterGyItIyTn-----lgdFeVeLyWyhSpkTCLNFy
d2mvza-  (   1 )                  makkGyilMen----ggkieFelfpneApvtvanFe
d2phcb1  (  86 )                                  ieIpVAYggefGpdIefVAq
d2wfia-  (   6 )                 qr-prCfFdIAinnqpagrVvFeLfsdvCpkTCeNFr
d4r3fa-  (   6 )             nlePqPtGaviihtt-----qgdlkvelFAkqtpltCrnFl
                                      bbbb         bbbbbb      aaaaaaa

                             60        70        80        90        100 
d1v9ta-  (  34 )    dYVn-----------s----gfYnnTTFHrVipgfMIqGGGFte-qmqqk
d1w74a-  (  44 )    gLAqGtkdYstqNAsggpsgpFYdgAvFHrViqgfMIqGGDP-tgtgrg-
d1x7fa1  ( 258 )    --------------evEkrATlqelHvrrGditeymVrSTeVrkkYkdyd
d1zx8a1  (  28 )    e---------------------kIpfesvVntwgeEIyFsTpVnvqkenp
d2b71a1  (  68 )    tLCe---------m------gfYdnTiFHrVipnfVIqGGDp-tgtgkgG
d2mvza-  (  33 )    klAne---------------gfYngltFhrvipgfvSqGgCprg------
d2phcb1  ( 106 )    yn--------glsvddVieiHsp-lYrVyfLgfpGfAyLggMderI---a
d2wfia-  (  42 )    CLCtgekgtGk----stqkpLhYks-lFHrVvkdfmVqGgDfsegngrgG
d4r3fa-  (  42 )    qHSl---------d------gyYdgtiFHrlvpgfiiqGGDp-tgtghgG
                    aa                         bb bb   bbbb           

                             110       120       130       140       150 
d1v9ta-  (  69 )    pn----------------------------ppikNeAdn-glrN-trgtI
d1w74a-  (  92 )    -gPgy--------------------------kfadefhp-elqFdkpyLL
d1x7fa1  ( 294 )    Fpvre-----------------------------------Sv-lQerGqV
d1zx8a1  (  58 )    r----evVe-------------------------------------igdV
d2b71a1  ( 102 )    kSiyg-------------------------eyFedeink-elkHtgaGiL
d2mvza-  (  62 )    -----------------------ngtGdAgytipcEtdnnphrH-vtGAM
d2phcb1  ( 146 )    Tprle-----------------------------------prlkVpagSV
d2wfia-  (  88 )    ESIyg-------------------------gffedesf--avkHnkefLL
d4r3fa-  (  76 )    eSiYdgGafsgdldpWpmdqRkghnagpmGvnFkdefhs-rlkFnrrGll
                                                                    bb

                             160       170       180       190       200 
d1v9ta-  (  89 )    AMartadkdsatSqFFINVadNafldhgqrdfGyAVFGkVvk--gmdvAd
d1w74a-  ( 114 )    AMana-gpgtNgSqFFITVgkTphlnr-----rhTIFGeVidaeSqrvVe
d1x7fa1  ( 308 )    VIGNnsfgky-kGELQIIlke------mpiderKNiVGtIA-eeelf---
d1zx8a1  (  67 )    GYwppg------kALCLFfgkTps-ddkiqPasaVnvIgIve----gldL
d2b71a1  ( 126 )    SMsnn-gpntNsSqFfITLaplphLdg-----khTIFArVsk--nmtCIe
d2mvza-  (  88 )    SMAHr-grdtGsCqFFivHepqphldg-----vHtvFGqvts--gmdvvr
d2phcb1  ( 162 )    GIAg--------kqTGWYAie------spgg--wrIIGrIp-lrTFnpgk
d2wfia-  ( 111 )    SManr-gkdtNgSqFFITTkpTphldg-----hhVVFGqVis--GqeVVr
d4r3fa-  ( 125 )    GMAnegapdtngSqFFFtlgkAeelnn-----kntlFGrvAagdtiynlm
                    bb            bbbb                 bbbbb          

                             210       220       230   
d1v9ta-  ( 137 )    kISqvpthdvgpyqnvPskpVvIlsAtvlp     
d1w74a-  ( 158 )    aISktatd----gndrPtdpVvIesItis      
d1x7fa1  ( 347 )    -lLdyVga-----------wtqFtCve        
d1zx8a1  ( 110 )    kIk---------------dgekVaVrfAs-----s
d2b71a1  ( 168 )    nIasvqtt----atnkPifdLkIlrTst       
d2mvza-  ( 130 )    tMk---------------ngDvMkevkvfdep   
d2phcb1  ( 195 )    vppSiVlp-----------gdyVkFvpi---deFw
d2wfia-  ( 153 )    eIEnqktda----askPfaeVrIlsCgel      
d4r3fa-  ( 170 )    kWGeaeli---egterPqypvkitnieillnpfpd
                                          bbbbb
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Peptidyl-prolyl cis-trans isomerase A, PpiACyclophilin (peptidylprolyl isomerase)Escherichia coli [TaxId: 562]view
Peptidyl-prolyl cis-trans isomerase A, PpiACyclophilin (peptidylprolyl isomerase)Mycobacterium tuberculosis [TaxId: 1773]view
Outer surface protein, C-terminal domainOuter surface protein, C-terminal domainBacillus cereus [TaxId: 1396]view
Hypothetical protein TM1367TM1367-likeThermotoga maritima [TaxId: 2336]view
Cyclophilin-like protein PY00693Cyclophilin (peptidylprolyl isomerase)Plasmodium yoelii [TaxId: 5861]view
automated matchesautomated matchesGeobacillus kaustophilus [TaxId: 235909]view
Uncharacterized protein PH0987PH0987 C-terminal domain-likePyrococcus horikoshii [TaxId: 53953]view
automated matchesCyclophilin (peptidylprolyl isomerase)Human (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesChaetomium thermophilum [TaxId: 759272]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230
- - - - - - - - - - - - - A G D P H V L L T T S - - - - - A G N I E L E L D K Q K A P V S V Q N F V D Y V N - - - - - - - - - - - S - - - - G F Y N N T T F H R V I P G F M I Q G G G F T E - Q M Q Q K P N - - - - - - - - - - - - - - - - - - - - - - - - - - - - P P I K N E A D N - G L R N - T R G T I A M A R T A D K D S A T S Q F F I N V A D N A F L D H G Q R D F G Y A V F G K V V K - - G M D V A D K I S Q V P T H D V G P Y Q N V P S K P V V I L S A T V L P - - - - -
- - - - - - - - - - - - - L A T A T A T L H T N - - - - - R G D I K I A L F G N H A P K T V A N F V G L A Q G T K D Y S T Q N A S G G P S G P F Y D G A V F H R V I Q G F M I Q G G D P - T G T G R G - - G P G Y - - - - - - - - - - - - - - - - - - - - - - - - - - K F A D E F H P - E L Q F D K P Y L L A M A N A - G P G T N G S Q F F I T V G K T P H L N R - - - - - R H T I F G E V I D A E S Q R V V E A I S K T A T D - - - - G N D R P T D P V V I E S I T I S - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - M L Q L K V H F V D - - - - - - - E A T - - - - - - - - - - - - - - - E V E K R A T L Q E L H V R R G D I T E Y M V R S T E V R K K Y K D Y D F P V R E - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - S V - L Q E R G Q V V I G N N S F G K Y - K G E L Q I I L K E - - - - - - M P I D E R K N I V G T I A - E E E L F - - - - L L D Y V G A - - - - - - - - - - - W T Q F T C V E - - - - - - - -
- - - - - - - - - - - - - - - - - R V E L L F E - - - - - S G K C V I D L N E E - - Y E V V K L L K E - - - - - - - - - - - - - - - - - - - - - K I P F E S V V N T W G E E I Y F S T P V N V Q K E N P R - - - - E V V E - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - I G D V G Y W P P G - - - - - - K A L C L F F G K T P S - D D K I Q P A S A V N V I G I V E - - - - G L D L K I K - - - - - - - - - - - - - - - D G E K V A V R F A S - - - - - S
L E E K I A Y Y K M K G H T E R G Y I T I Y T N - - - - - L G D F E V E L Y W Y H S P K T C L N F Y T L C E - - - - - - - - - M - - - - - - G F Y D N T I F H R V I P N F V I Q G G D P - T G T G K G G K S I Y G - - - - - - - - - - - - - - - - - - - - - - - - - E Y F E D E I N K - E L K H T G A G I L S M S N N - G P N T N S S Q F F I T L A P L P H L D G - - - - - K H T I F A R V S K - - N M T C I E N I A S V Q T T - - - - A T N K P I F D L K I L R T S T - - - - - - -
- - - - - - - - - - - - - - M A K K G Y I L M E N - - - - G G K I E F E L F P N E A P V T V A N F E K L A N E - - - - - - - - - - - - - - - G F Y N G L T F H R V I P G F V S Q G G C P R G - - - - - - - - - - - - - - - - - - - - - - - - - - - - - N G T G D A G Y T I P C E T D N N P H R H - V T G A M S M A H R - G R D T G S C Q F F I V H E P Q P H L D G - - - - - V H T V F G Q V T S - - G M D V V R T M K - - - - - - - - - - - - - - - N G D V M K E V K V F D E P - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - I E I P V A Y G G E F G P D I E F V A Q Y N - - - - - - - - G L S V D D V I E I H S P - L Y R V Y F L G F P G F A Y L G G M D E R I - - - A T P R L E - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - P R L K V P A G S V G I A G - - - - - - - - K Q T G W Y A I E - - - - - - S P G G - - W R I I G R I P - L R T F N P G K V P P S I V L P - - - - - - - - - - - G D Y V K F V P I - - - D E F W
- - - - - - - - - - - - - Q R - P R C F F D I A I N N Q P A G R V V F E L F S D V C P K T C E N F R C L C T G E K G T G K - - - - S T Q K P L H Y K S - L F H R V V K D F M V Q G G D F S E G N G R G G E S I Y G - - - - - - - - - - - - - - - - - - - - - - - - - G F F E D E S F - - A V K H N K E F L L S M A N R - G K D T N G S Q F F I T T K P T P H L D G - - - - - H H V V F G Q V I S - - G Q E V V R E I E N Q K T D A - - - - A S K P F A E V R I L S C G E L - - - - - -
- - - - - - - - - N L E P Q P T G A V I I H T T - - - - - Q G D L K V E L F A K Q T P L T C R N F L Q H S L - - - - - - - - - D - - - - - - G Y Y D G T I F H R L V P G F I I Q G G D P - T G T G H G G E S I Y D G G A F S G D L D P W P M D Q R K G H N A G P M G V N F K D E F H S - R L K F N R R G L L G M A N E G A P D T N G S Q F F F T L G K A E E L N N - - - - - K N T L F G R V A A G D T I Y N L M K W G E A E L I - - - E G T E R P Q Y P V K I T N I E I L L N P F P D

 

 

 

 

 

Member Chain UniProtKB GO term
d1v9ta_ A P0AFL3 GO:0000413
d1v9ta_ A P0AFL3 GO:0003755
d1v9ta_ A P0AFL3 GO:0006457
d1v9ta_ A P0AFL3 GO:0030288
d1v9ta_ A P0AFL3 GO:0042597
d1v9ta_ A P0AFL3 GO:0000413
d1v9ta_ A P0AFL3 GO:0003755
d1v9ta_ A P0AFL3 GO:0006457
d1v9ta_ A P0AFL3 GO:0030288
d1v9ta_ A P0AFL3 GO:0042597
d1w74a_ A P9WHW3 GO:0000413
d1w74a_ A P9WHW3 GO:0003755
d1w74a_ A P9WHW3 GO:0003824
d1w74a_ A P9WHW3 GO:0005576
d1w74a_ A P9WHW3 GO:0005737
d1w74a_ A P9WHW3 GO:0005829
d1w74a_ A P9WHW3 GO:0005886
d1w74a_ A P9WHW3 GO:0006457
d1w74a_ A P9WHW3 GO:0009274
d1w74a_ A P9WHW3 GO:0010039
d1w74a_ A P9WHW3 GO:0000413
d1w74a_ A P9WHW3 GO:0003755
d1w74a_ A P9WHW3 GO:0003824
d1w74a_ A P9WHW3 GO:0005576
d1w74a_ A P9WHW3 GO:0005737
d1w74a_ A P9WHW3 GO:0005829
d1w74a_ A P9WHW3 GO:0005886
d1w74a_ A P9WHW3 GO:0006457
d1w74a_ A P9WHW3 GO:0009274
d1w74a_ A P9WHW3 GO:0010039
d2b71a1 A Q7RRM6 GO:0000413
d2b71a1 A Q7RRM6 GO:0003755
d2b71a1 A Q7RRM6 GO:0003824
d2b71a1 A Q7RRM6 GO:0006457
d2b71a1 A Q7RRM6 GO:0071013
d2b71a1 A Q7RRM6 GO:0000413
d2b71a1 A Q7RRM6 GO:0003755
d2b71a1 A Q7RRM6 GO:0003824
d2b71a1 A Q7RRM6 GO:0006457
d2b71a1 A Q7RRM6 GO:0071013
d2phcb1 B O58715 GO:0005524
d2phcb1 B O58715 GO:0016787
d2phcb1 B O58715 GO:0005524
d2phcb1 B O58715 GO:0016787
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in