PASS2.8 - Home

solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x

beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x

hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x

                             10        20        30        40        50  
d1hcda-  (   1 )        mgnrAfksh-hghflSaege--avkthhgh-hdhhthfhvenhg--
d3llpa1  (   7 )    aeavqiqFGLiNc-gnkyLTAeafgfkVnAsassl-kkkQiWTle--ags
d3llpa2  ( 141 )          qvnIySvtrkryAhlsa-adeIAVdrdvpwgvdSlItlafqd--
d3llpa3  ( 260 )        caqVVLqAa-nernVSTrg--mdLSAnqdee-tdqEtFqleidrdt
d3llpa4  ( 383 )        rpiIvFrGe-h-gfIGcrt--gtLDAnrssy-d---vFqlefnd--
                           bbbb      bbbb      bbbbb          bbbb    

                             60        70        80        90        100 
d1hcda-  (  41 )    gkvAlkthcgkylSigdhkqvylshhlhgdhslFhlehhg-gkvsikGhh
d3llpa1  (  58 )    aAvcLrShlgryLaAdkdGnVtCerevpgpdCrFlivahddgrwSLqSea
d3llpa2  ( 184 )    qrySVqTadhrfLrh--dGr---LvarpepaTGYtlefr---kVAFrDce
d3llpa3  ( 303 )    kkCAFrThtgkYWtltatggVqStassknasCyFdIewrd-rrITLrAsn
d3llpa4  ( 421 )    gAyNIkdstgkyWtvgsdsaVtSsgdtpv---dFfFefcdynkVAIkvg-
                      bbbb     bbbb     bbbbb         bbbb     bbbb   

                             110       120       130   
d1hcda-  (  90 )    -hhyiSAd-hhghvstk-ehhdhdttFeeiii   
d3llpa1  ( 108 )    hrryFGgt-ed-rLsCfaqtvspaekWsvhiamhp
d3llpa2  ( 228 )    -gryLaPsgpsGtLkAg----gkdelFaleqs   
d3llpa3  ( 352 )    -gkFVtSk-knGqLaAsvetAgdsElFlmklin  
d3llpa4  ( 467 )    -gryLkgd-hagvLkAsaetvdpaSlWey      
                       bbbb      bbbb     333  bbb

Domains
Outliers

Domain ID	Name	Family	Source	STRING-DB
d1hcda- # Domain Specific Files ATM file: Atomic coordinates by ASTRAL ATM2ALI file: Amino acid sequences by ATM2ALI SST file: Secondary structure by SSTRUC PSA file: solvent accessibility by PSA HBD file: Hydrogen bonds by HBOND PSE file: PyMol session file for conserved interactions PDBSUM1: Topological diagram d1hcda- # Links to other databases and tools RCSB-PDB: Research Collaboratory for Structural Bioinformatics SCOP: Structural Classification of Proteins EBI: European Bioinformatics Institute HOMSTRAD: Homologous Structure Alignment Database DDBASE: Dial-Derived Domain Database CATH: Class Architecture Topology and Homologous sfily PALI: Phylogeny and ALIgnment of homologous protein structures MODBASE: A Database of Annotated Comparative Protein Structure Models 3Dee: A Database of Protein Domain Definition PQS: Protein Quaternary Structure Query Form at the EBI LPC/CSU: Ligand-Protein Contacts & Contacts of Structural LPFC: A Library of Protein Family Cores MMDB: Molecular Modelling DataBase,NCBI CE: Databases and Tools for 3-D Protein Structure Comparison and Alignment PDBSUM: Summaries and structural analyses of PDB data files Pfam: Protein families database of alignments and HMMs	Histidine-rich actin-binding protein (hisactophilin)	Histidine-rich actin-binding protein (hisactophilin)	Slime mold (Dictyostelium discoideum) [TaxId: 44689]	view
d3llpa1 # Domain Specific Files ATM file: Atomic coordinates by ASTRAL ATM2ALI file: Amino acid sequences by ATM2ALI SST file: Secondary structure by SSTRUC PSA file: solvent accessibility by PSA HBD file: Hydrogen bonds by HBOND PSE file: PyMol session file for conserved interactions PDBSUM1: Topological diagram d3llpa1 # Links to other databases and tools RCSB-PDB: Research Collaboratory for Structural Bioinformatics SCOP: Structural Classification of Proteins EBI: European Bioinformatics Institute HOMSTRAD: Homologous Structure Alignment Database DDBASE: Dial-Derived Domain Database CATH: Class Architecture Topology and Homologous sfily PALI: Phylogeny and ALIgnment of homologous protein structures MODBASE: A Database of Annotated Comparative Protein Structure Models 3Dee: A Database of Protein Domain Definition PQS: Protein Quaternary Structure Query Form at the EBI LPC/CSU: Ligand-Protein Contacts & Contacts of Structural LPFC: A Library of Protein Family Cores MMDB: Molecular Modelling DataBase,NCBI CE: Databases and Tools for 3-D Protein Structure Comparison and Alignment PDBSUM: Summaries and structural analyses of PDB data files Pfam: Protein families database of alignments and HMMs	Fascin	Fascin	Human (Homo sapiens) [TaxId: 9606]	view
d3llpa2 # Domain Specific Files ATM file: Atomic coordinates by ASTRAL ATM2ALI file: Amino acid sequences by ATM2ALI SST file: Secondary structure by SSTRUC PSA file: solvent accessibility by PSA HBD file: Hydrogen bonds by HBOND PSE file: PyMol session file for conserved interactions PDBSUM1: Topological diagram d3llpa2 # Links to other databases and tools RCSB-PDB: Research Collaboratory for Structural Bioinformatics SCOP: Structural Classification of Proteins EBI: European Bioinformatics Institute HOMSTRAD: Homologous Structure Alignment Database DDBASE: Dial-Derived Domain Database CATH: Class Architecture Topology and Homologous sfily PALI: Phylogeny and ALIgnment of homologous protein structures MODBASE: A Database of Annotated Comparative Protein Structure Models 3Dee: A Database of Protein Domain Definition PQS: Protein Quaternary Structure Query Form at the EBI LPC/CSU: Ligand-Protein Contacts & Contacts of Structural LPFC: A Library of Protein Family Cores MMDB: Molecular Modelling DataBase,NCBI CE: Databases and Tools for 3-D Protein Structure Comparison and Alignment PDBSUM: Summaries and structural analyses of PDB data files Pfam: Protein families database of alignments and HMMs	Fascin	Fascin	Human (Homo sapiens) [TaxId: 9606]	view
d3llpa3 # Domain Specific Files ATM file: Atomic coordinates by ASTRAL ATM2ALI file: Amino acid sequences by ATM2ALI SST file: Secondary structure by SSTRUC PSA file: solvent accessibility by PSA HBD file: Hydrogen bonds by HBOND PSE file: PyMol session file for conserved interactions PDBSUM1: Topological diagram d3llpa3 # Links to other databases and tools RCSB-PDB: Research Collaboratory for Structural Bioinformatics SCOP: Structural Classification of Proteins EBI: European Bioinformatics Institute HOMSTRAD: Homologous Structure Alignment Database DDBASE: Dial-Derived Domain Database CATH: Class Architecture Topology and Homologous sfily PALI: Phylogeny and ALIgnment of homologous protein structures MODBASE: A Database of Annotated Comparative Protein Structure Models 3Dee: A Database of Protein Domain Definition PQS: Protein Quaternary Structure Query Form at the EBI LPC/CSU: Ligand-Protein Contacts & Contacts of Structural LPFC: A Library of Protein Family Cores MMDB: Molecular Modelling DataBase,NCBI CE: Databases and Tools for 3-D Protein Structure Comparison and Alignment PDBSUM: Summaries and structural analyses of PDB data files Pfam: Protein families database of alignments and HMMs	Fascin	Fascin	Human (Homo sapiens) [TaxId: 9606]	view
d3llpa4 # Domain Specific Files ATM file: Atomic coordinates by ASTRAL ATM2ALI file: Amino acid sequences by ATM2ALI SST file: Secondary structure by SSTRUC PSA file: solvent accessibility by PSA HBD file: Hydrogen bonds by HBOND PSE file: PyMol session file for conserved interactions PDBSUM1: Topological diagram d3llpa4 # Links to other databases and tools RCSB-PDB: Research Collaboratory for Structural Bioinformatics SCOP: Structural Classification of Proteins EBI: European Bioinformatics Institute HOMSTRAD: Homologous Structure Alignment Database DDBASE: Dial-Derived Domain Database CATH: Class Architecture Topology and Homologous sfily PALI: Phylogeny and ALIgnment of homologous protein structures MODBASE: A Database of Annotated Comparative Protein Structure Models 3Dee: A Database of Protein Domain Definition PQS: Protein Quaternary Structure Query Form at the EBI LPC/CSU: Ligand-Protein Contacts & Contacts of Structural LPFC: A Library of Protein Family Cores MMDB: Molecular Modelling DataBase,NCBI CE: Databases and Tools for 3-D Protein Structure Comparison and Alignment PDBSUM: Summaries and structural analyses of PDB data files Pfam: Protein families database of alignments and HMMs	Fascin	Fascin	Human (Homo sapiens) [TaxId: 9606]	view

No outliers

Feature	Download
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

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A	E	A	V	Q	I	Q	F	G	L	I	N	C	-	G	N	K	Y	L	T	A	E	A	F	G	F	K	V	N	A	S	A	S	S	L	-	K	K	K	Q	I	W	T	L	E	-	-	A	G	S	A	A	V	C	L	R	S	H	L	G	R	Y	L	A	A	D	K	D	G	N	V	T	C	E	R	E	V	P	G	P	D	C	R	F	L	I	V	A	H	D	D	G	R	W	S	L	Q	S	E	A	H	R	R	Y	F	G	G	T	-	E	D	-	R	L	S	C	F	A	Q	T	V	S	P	A	E	K	W	S	V	H	I	A	M	H	P
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-	-	-	-	R	P	I	I	V	F	R	G	E	-	H	-	G	F	I	G	C	R	T	-	-	G	T	L	D	A	N	R	S	S	Y	-	D	-	-	-	V	F	Q	L	E	F	N	D	-	-	G	A	Y	N	I	K	D	S	T	G	K	Y	W	T	V	G	S	D	S	A	V	T	S	S	G	D	T	P	V	-	-	-	D	F	F	F	E	F	C	D	Y	N	K	V	A	I	K	V	G	-	-	G	R	Y	L	K	G	D	-	H	A	G	V	L	K	A	S	A	E	T	V	D	P	A	S	L	W	E	Y	-	-	-	-	-	-

Member	Chain	UniProtKB	GO term
d1hcda_	A	P13231	GO:0003779
d1hcda_	A	P13231	GO:0003785
d1hcda_	A	P13231	GO:0005504
d1hcda_	A	P13231	GO:0005737
d1hcda_	A	P13231	GO:0005829
d1hcda_	A	P13231	GO:0005886
d1hcda_	A	P13231	GO:0006972
d1hcda_	A	P13231	GO:0008289
d1hcda_	A	P13231	GO:0010447
d1hcda_	A	P13231	GO:0015629
d1hcda_	A	P13231	GO:0030041
d1hcda_	A	P13231	GO:0030674
d1hcda_	A	P13231	GO:0030863
d1hcda_	A	P13231	GO:0045335
d1hcda_	A	P13231	GO:0051015
d1hcda_	A	P13231	GO:0003779
d1hcda_	A	P13231	GO:0003785
d1hcda_	A	P13231	GO:0005504
d1hcda_	A	P13231	GO:0005737
d1hcda_	A	P13231	GO:0005829
d1hcda_	A	P13231	GO:0005886
d1hcda_	A	P13231	GO:0006972
d1hcda_	A	P13231	GO:0008289
d1hcda_	A	P13231	GO:0010447
d1hcda_	A	P13231	GO:0015629
d1hcda_	A	P13231	GO:0030041
d1hcda_	A	P13231	GO:0030674
d1hcda_	A	P13231	GO:0030863
d1hcda_	A	P13231	GO:0045335
d1hcda_	A	P13231	GO:0051015

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A	E	A	V	Q	I	Q	F	G	L	I	N	C	-	G	N	K	Y	L	T	A	E	A	F	G	F	K	V	N	A	S	A	S	S	L	-	K	K	K	Q	I	W	T	L	E	-	-	A	G	S	A	A	V	C	L	R	S	H	L	G	R	Y	L	A	A	D	K	D	G	N	V	T	C	E	R	E	V	P	G	P	D	C	R	F	L	I	V	A	H	D	D	G	R	W	S	L	Q	S	E	A	H	R	R	Y	F	G	G	T	-	E	D	-	R	L	S	C	F	A	Q	T	V	S	P	A	E	K	W	S	V	H	I	A	M	H	P
-	-	-	-	-	-	Q	V	N	I	Y	S	V	T	R	K	R	Y	A	H	L	S	A	-	A	D	E	I	A	V	D	R	D	V	P	W	G	V	D	S	L	I	T	L	A	F	Q	D	-	-	Q	R	Y	S	V	Q	T	A	D	H	R	F	L	R	H	-	-	D	G	R	-	-	-	L	V	A	R	P	E	P	A	T	G	Y	T	L	E	F	R	-	-	-	K	V	A	F	R	D	C	E	-	G	R	Y	L	A	P	S	G	P	S	G	T	L	K	A	G	-	-	-	-	G	K	D	E	L	F	A	L	E	Q	S	-	-	-
-	-	-	-	C	A	Q	V	V	L	Q	A	A	-	N	E	R	N	V	S	T	R	G	-	-	M	D	L	S	A	N	Q	D	E	E	-	T	D	Q	E	T	F	Q	L	E	I	D	R	D	T	K	K	C	A	F	R	T	H	T	G	K	Y	W	T	L	T	A	T	G	G	V	Q	S	T	A	S	S	K	N	A	S	C	Y	F	D	I	E	W	R	D	-	R	R	I	T	L	R	A	S	N	-	G	K	F	V	T	S	K	-	K	N	G	Q	L	A	A	S	V	E	T	A	G	D	S	E	L	F	L	M	K	L	I	N	-	-
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A	E	A	V	Q	I	Q	F	G	L	I	N	C	-	G	N	K	Y	L	T	A	E	A	F	G	F	K	V	N	A	S	A	S	S	L	-	K	K	K	Q	I	W	T	L	E	-	-	A	G	S	A	A	V	C	L	R	S	H	L	G	R	Y	L	A	A	D	K	D	G	N	V	T	C	E	R	E	V	P	G	P	D	C	R	F	L	I	V	A	H	D	D	G	R	W	S	L	Q	S	E	A	H	R	R	Y	F	G	G	T	-	E	D	-	R	L	S	C	F	A	Q	T	V	S	P	A	E	K	W	S	V	H	I	A	M	H	P
-	-	-	-	-	-	Q	V	N	I	Y	S	V	T	R	K	R	Y	A	H	L	S	A	-	A	D	E	I	A	V	D	R	D	V	P	W	G	V	D	S	L	I	T	L	A	F	Q	D	-	-	Q	R	Y	S	V	Q	T	A	D	H	R	F	L	R	H	-	-	D	G	R	-	-	-	L	V	A	R	P	E	P	A	T	G	Y	T	L	E	F	R	-	-	-	K	V	A	F	R	D	C	E	-	G	R	Y	L	A	P	S	G	P	S	G	T	L	K	A	G	-	-	-	-	G	K	D	E	L	F	A	L	E	Q	S	-	-	-
-	-	-	-	C	A	Q	V	V	L	Q	A	A	-	N	E	R	N	V	S	T	R	G	-	-	M	D	L	S	A	N	Q	D	E	E	-	T	D	Q	E	T	F	Q	L	E	I	D	R	D	T	K	K	C	A	F	R	T	H	T	G	K	Y	W	T	L	T	A	T	G	G	V	Q	S	T	A	S	S	K	N	A	S	C	Y	F	D	I	E	W	R	D	-	R	R	I	T	L	R	A	S	N	-	G	K	F	V	T	S	K	-	K	N	G	Q	L	A	A	S	V	E	T	A	G	D	S	E	L	F	L	M	K	L	I	N	-	-
-	-	-	-	R	P	I	I	V	F	R	G	E	-	H	-	G	F	I	G	C	R	T	-	-	G	T	L	D	A	N	R	S	S	Y	-	D	-	-	-	V	F	Q	L	E	F	N	D	-	-	G	A	Y	N	I	K	D	S	T	G	K	Y	W	T	V	G	S	D	S	A	V	T	S	S	G	D	T	P	V	-	-	-	D	F	F	F	E	F	C	D	Y	N	K	V	A	I	K	V	G	-	-	G	R	Y	L	K	G	D	-	H	A	G	V	L	K	A	S	A	E	T	V	D	P	A	S	L	W	E	Y	-	-	-	-	-	-

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