Superfamily : 48056 [ Di-copper centre-containing domain ]
Class : All alpha proteins
Fold : Di-copper centre-containing domain
# of Members : 5
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1hc1a2  ( 136 )                                                      
d1js8a1  (2503 )                                                  aiiR
d1llaa2  ( 110 )                                                      
d3awua1  (   2 )                                                   tvR
d4z0ya-  (   1 )    apitAPditsiÇkdAssgignqegAirtrkÇçppslgkikdffpndvrmR
                                                                      

                             60        70        80        90        100 
d1hc1a2  ( 136 )     plyqit-phmFtnsevidkaysakmtqkpgtfnvsfknreqrVayfged
d1js8a1  (2507 )    knVnsLtpsDikeLrdAMakVqad--t------------------sdnGY
d1llaa2  ( 110 )     pVqeif-pDkFipsaaineafkki------lvt-gildpeyrLayyRed
d3awua1  (   5 )    knQatltadekrrFvaAVleLKrs--g---------------------rY
d4z0ya-  (  55 )    WpAhg-tkkqvddYrrAiaaMralpdd------------------dPrSF
                                  aaaaaaaaa                           

                             110       120       130       140       150 
d1hc1a2  ( 188 )    igmNihHVtwHmdfPfwwedsygyhldrK--GelFfwvHhqLTarFdfeR
d1js8a1  (2537 )    qkIAsYHGipl-sÇhy---engtayaÇCqhgmVTFPNWHRLLTKQMEdAL
d1llaa2  ( 167 )    vgiNahHwhwhlvypstwnpyfgkkkdrK--gelFyymHqqMCarYdcer
d3awua1  (  32 )    defVrtHnefimsDtd---s----gerTGhrSPSFLPWhRrFLLdFEqAL
d4z0ya-  (  87 )    vsqAkiHÇAYCngGYtqvdsgfpdidiqiHnSWlFFPFHRWYlYFYEril
                    aaaaaaaaaaa                       aaaaaaaaaaaaaaaa

                             160       170       180       190       200 
d1hc1a2  ( 236 )    lsnwld---pVdel-hWd------riIreGfaPlTsyky-ggeFPvrp--
d1js8a1  (2583 )    vakg--ShvGIPYWdWTttfanLpvLVteek--------------dNsFh
d1llaa2  ( 216 )    lsngmh---rMlpfnnFd------epL-agyaPhLthvasgkyySpRp--
d3awua1  (  75 )    qsvd--ssVtLPYWdWSadrtvrasLW-apdFLGgtGrstdgrVmdGpFA
d4z0ya-  ( 137 )    GslidepnFAlPYWKWdepkGMpisiFlg-------dasnplydqyRDan
                    aa                                                

                             210       220       230       240       250 
d1hc1a2  ( 273 )    --------------dnihFedVdgvahvhdLeitesrIheAIdh--GyIt
d1js8a1  (2617 )    ----hAhIdvan---tdTtrspraq-LfsfFyrqIAlALeq-t-------
d1llaa2  ( 254 )    --------------dglkLrdL-gdIeiseMvrmrerIldSIhl--gyVi
d3awua1  ( 122 )    astgnWpInvrvdsrtyLrRsLggsvaeLPtraeVesVLai-saYDlppy
d4z0ya-  ( 181 )    Hiedrvdldydgdkd---ipdqqvacnlstvyrDlvrnGvdptsFFGgkY
                                                 aaaaaaaaaa           

                             260       270       280       290       300 
d1hc1a2  ( 307 )    dsdghtidIrqpkGielLGdIIESSkySsnvqyYgsLHntAhvMLgrQgd
d1js8a1  (2659 )    dFç-------------dFEiqFEi------------gHnaIhswVGGs--
d1llaa2  ( 287 )    sedgshktLdelhGtdiLGaLVESSyeSvnheyYgnLHnwGhvTMArIhD
d3awua1  ( 171 )    nsaSe-----------GFRNhLEGwrg-------vnLhnrVhvWVg----
d4z0ya-  ( 231 )    vAgdspvan-----gdpsvGsvea------------gStAvhrWvGdptq
                                     aaaaaa              aaaaaaaa     

                             310       320       330       340       350 
d1hc1a2  ( 357 )    phgkfnlppgVMehfeTATrDpSFFrLHkYMdnIFkkHtdsf        
d1js8a1  (2682 )    -sp------yGMstlhyTSYDPLFYLHHSNTDRIWSVWQaLQkyrglpyn
d1llaa2  ( 337 )    PdgrfheepgVMsdtSTSLRDpiFYnWHrFIdnIFheYkntlk       
d3awua1  ( 199 )    ---------GQMatg-VSPNDPVFWLHHAYVDkLWaeWqrrhp------d
d4z0ya-  ( 265 )    pnn------EDMGnfYSAGYDPvFYIHHAnvDRMWklWkellpgHvdit-
                                          aaaaaaaaaaaaaaaaa           

                             360       370       380       390       400 
d1hc1a2                                                               
d1js8a1  (2725 )    tAnçei------nkLvkpLkPFnldtNpnavTka--hstGatSFdyhkLg
d1llaa2                                                               
d3awua1  ( 233 )    saYvptggtpdVVdlnetMkpwn-------------tVrPadLldhta-y
d4z0ya-  ( 309 )    ----------dpdWlnASYvFYden-------kdlvrvyn-dCvnldklk
                                                                      

                             410       420   
d1hc1a2                                      
d1js8a1  (2767 )    YdYdnlnFhgmtipeLeehLkeiqh
d1llaa2                                      
d3awua1  ( 269 )    YtFda                    
d4z0ya-  ( 342 )    YnFien
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Arthropod hemocyaninHemocyanin middle domainSpiny lobster (Panulirus interruptus) [TaxId: 6735]view
Mollusc hemocyaninHemocyanin middle domainGiant octopus (Octopus dofleini) [TaxId: 267067]view
Arthropod hemocyaninHemocyanin middle domainHorseshoe crab (Limulus polyphemus) [TaxId: 6850]view
TyrosinaseTyrosinaseStreptomyces castaneoglobisporus [TaxId: 79261]view
automated matchesautomated matchesCoreopsis grandiflora [TaxId: 13449]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - P L Y Q I T - P H M F T N S E V I D K A Y S A K M T Q K P G T F N V S F K N R E Q R V A Y F G E D I G M N I H H V T W H M D F P F W W E D S Y G Y H L D R K - - G E L F F W V H H Q L T A R F D F E R L S N W L D - - - P V D E L - H W D - - - - - - R I I R E G F A P L T S Y K Y - G G E F P V R P - - - - - - - - - - - - - - - - D N I H F E D V D G V A H V H D L E I T E S R I H E A I D H - - G Y I T D S D G H T I D I R Q P K G I E L L G D I I E S S K Y S S N V Q Y Y G S L H N T A H V M L G R Q G D P H G K F N L P P G V M E H F E T A T R D P S F F R L H K Y M D N I F K K H T D S F - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - A I I R K N V N S L T P S D I K E L R D A M A K V Q A D - - T - - - - - - - - - - - - - - - - - - S D N G Y Q K I A S Y H G I P L - S C H Y - - - E N G T A Y A C C Q H G M V T F P N W H R L L T K Q M E D A L V A K G - - S H V G I P Y W D W T T T F A N L P V L V T E E K - - - - - - - - - - - - - - D N S F H - - - - H A H I D V A N - - - T D T T R S P R A Q - L F S F F Y R Q I A L A L E Q - T - - - - - - - D F C - - - - - - - - - - - - - D F E I Q F E I - - - - - - - - - - - - G H N A I H S W V G G S - - - S P - - - - - - Y G M S T L H Y T S Y D P L F Y L H H S N T D R I W S V W Q A L Q K Y R G L P Y N T A N C E I - - - - - - N K L V K P L K P F N L D T N P N A V T K A - - H S T G A T S F D Y H K L G Y D Y D N L N F H G M T I P E L E E H L K E I Q H
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - P V Q E I F - P D K F I P S A A I N E A F K K I - - - - - - L V T - G I L D P E Y R L A Y Y R E D V G I N A H H W H W H L V Y P S T W N P Y F G K K K D R K - - G E L F Y Y M H Q Q M C A R Y D C E R L S N G M H - - - R M L P F N N F D - - - - - - E P L - A G Y A P H L T H V A S G K Y Y S P R P - - - - - - - - - - - - - - - - D G L K L R D L - G D I E I S E M V R M R E R I L D S I H L - - G Y V I S E D G S H K T L D E L H G T D I L G A L V E S S Y E S V N H E Y Y G N L H N W G H V T M A R I H D P D G R F H E E P G V M S D T S T S L R D P I F Y N W H R F I D N I F H E Y K N T L K - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - T V R K N Q A T L T A D E K R R F V A A V L E L K R S - - G - - - - - - - - - - - - - - - - - - - - - R Y D E F V R T H N E F I M S D T D - - - S - - - - G E R T G H R S P S F L P W H R R F L L D F E Q A L Q S V D - - S S V T L P Y W D W S A D R T V R A S L W - A P D F L G G T G R S T D G R V M D G P F A A S T G N W P I N V R V D S R T Y L R R S L G G S V A E L P T R A E V E S V L A I - S A Y D L P P Y N S A S E - - - - - - - - - - - G F R N H L E G W R G - - - - - - - V N L H N R V H V W V G - - - - - - - - - - - - - G Q M A T G - V S P N D P V F W L H H A Y V D K L W A E W Q R R H P - - - - - - D S A Y V P T G G T P D V V D L N E T M K P W N - - - - - - - - - - - - - T V R P A D L L D H T A - Y Y T F D A - - - - - - - - - - - - - - - - - - - -
A P I T A P D I T S I C K D A S S G I G N Q E G A I R T R K C C P P S L G K I K D F F P N D V R M R W P A H G - T K K Q V D D Y R R A I A A M R A L P D D - - - - - - - - - - - - - - - - - - D P R S F V S Q A K I H C A Y C N G G Y T Q V D S G F P D I D I Q I H N S W L F F P F H R W Y L Y F Y E R I L G S L I D E P N F A L P Y W K W D E P K G M P I S I F L G - - - - - - - D A S N P L Y D Q Y R D A N H I E D R V D L D Y D G D K D - - - I P D Q Q V A C N L S T V Y R D L V R N G V D P T S F F G G K Y V A G D S P V A N - - - - - G D P S V G S V E A - - - - - - - - - - - - G S T A V H R W V G D P T Q P N N - - - - - - E D M G N F Y S A G Y D P V F Y I H H A N V D R M W K L W K E L L P G H V D I T - - - - - - - - - - - D P D W L N A S Y V F Y D E N - - - - - - - K D L V R V Y N - D C V N L D K L K Y N F I E N - - - - - - - - - - - - - - - - - - -

 

 

 

 

 

Member Chain UniProtKB GO term
d1hc1a2 A P04254 GO:0005344
d1hc1a2 A P04254 GO:0005576
d1hc1a2 A P04254 GO:0015671
d1hc1a2 A P04254 GO:0016491
d1hc1a2 A P04254 GO:0046872
d1hc1a2 A P04254 GO:0005344
d1hc1a2 A P04254 GO:0005576
d1hc1a2 A P04254 GO:0015671
d1hc1a2 A P04254 GO:0016491
d1hc1a2 A P04254 GO:0046872
d1js8a1 A O61363 GO:0016491
d1llaa2 A P04253 GO:0005344
d1llaa2 A P04253 GO:0005507
d1llaa2 A P04253 GO:0005576
d1llaa2 A P04253 GO:0015671
d1llaa2 A P04253 GO:0016491
d1llaa2 A P04253 GO:0031404
d1llaa2 A P04253 GO:0046872
d1llaa2 A P04253 GO:0005344
d1llaa2 A P04253 GO:0005507
d1llaa2 A P04253 GO:0005576
d1llaa2 A P04253 GO:0015671
d1llaa2 A P04253 GO:0016491
d1llaa2 A P04253 GO:0031404
d1llaa2 A P04253 GO:0046872
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in