Superfamily : 46565 [ Chaperone J-domain ]
Class : All alpha proteins
Fold : Long alpha-hairpin
# of Members : 10
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1fafa-  (   1 )    mdrvlsradkerllellklpr-----------------------qlwgdf
d1fpoa1  (   1 )              mdyFtlFglpary-----------------------qLdt
d1gh6a1  (   7 )          reeSlqLMdlLgler-----------------------sawgni
d1iura1  (  14 )         ilkevtsvveqAwklpe----------------------------
d1wjza1  (   8 )    maleqtlkk--dWysilgAdp-------------------------sanm
d2o37a-  (   1 )          mvketkLYdLLgvsp-------------------------sAne
d2qwob-  ( 813 )       dpeklkIleWiegkernIraLLstMhtVLwagetkWkpvgmadLvtp
d2yuaa1  (   8 )    s-qgdcsysrtalydllgvps-------------------------tAtq
d3ag7a1  ( 551 )    eeiknidakirkWssgksgnIrsLLstLqyILwsgs-gWkpvplmdMieg
d6rzya1  (   3 )              mdyYtllgvdk-------------------------gcse
                               aaaaa                                 a

                             60        70        80        90        100 
d1fafa-  (  28 )    grMqqaykqqslllhpdk------ggshalmqelnslWgtfktevy----
d1fpoa1  (  18 )    qaLslrfqdlqrqyhpdkf-asgsqaeqlaAvqqsatInqAwqtLrh---
d1gh6a1  (  28 )    plMrkaYlkkCkeFhpdk------ggdeekMkkMNtlYkkmEdgvkyahq
d1iura1  (  31 )    serkkiirrlylkwhpdknpe---n--hdiAnevfkhlqnEinrlek---
d1wjza1  (  31 )    sdlkqkyqklillyhpdkqsadvpagtmeeCmqkfieidqAwkilGn---
d2o37a-  (  20 )    qeLkkgyrkAalkyhpdkp---------tGdtekfkeIseAfeILnd---
d2qwob-  ( 860 )    eqVkkvyrkAvlvVhpckAt-----gq--pyeqyAkmIfmELndAws---
d2yuaa1  (  32 )    aqikaayyrqcflyhpdrns------gsaeaaerftrisqAyvvlgs---
d3ag7a1  ( 600 )    naVrkSYqrAlliLhpdkLqq---kgasanqkymAekVfelLqeAwd---
d6rzya1  (  18 )    ddlrraylklamkwhpdkh-vnk--gskveAeekfkniceAysvlsd---
                    aaaaaaaaaaaaa               aaaaaaaaaaaaaaaaa     

                             110       120       130       140       150 
d1fafa-  (  68 )    -----nlrmnlggtgf----------------------------------
d1fpoa1  (  64 )    ---plmRaeyllslhg                                  
d1gh6a1  (  72 )    pdfgg----------fwdateIptYgtdeWeqWwnafneenlfcseemps
d1iura1  (  73 )    -----qafld------qnadrasrrtf                       
d1wjza1  (  78 )    ---eetkkkYdlqr                                    
d2o37a-  (  58 )    ---pqkreiYdqyGleaArsggpsfgp                       
d2qwob-  ( 900 )    -----efenq                                        
d2yuaa1  (  73 )    ---atlrrkydrgllsdedlrgpg                          
d3ag7a1  ( 644 )    -----hfntl------gp                                
d6rzya1  (  62 )    ---nekrvkydl                                      
                         aaaa                                         

                          
d1fafa-  (  79 )    -----q
d1fpoa1                   
d1gh6a1  ( 112 )    sddeat
d1iura1                   
d1wjza1                   
d2o37a-                   
d2qwob-                   
d2yuaa1                   
d3ag7a1                   
d6rzya1
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Large T antigen, the N-terminal J domainChaperone J-domainMurine polyomavirus [TaxId: 10634]view
HSC20 (HSCB), N-terminal (J) domainChaperone J-domainEscherichia coli [TaxId: 562]view
Large T antigen, the N-terminal J domainChaperone J-domainSimian virus 40, Sv40 [TaxId: 10633]view
Hypothetical protein KIAA0730Chaperone J-domainHuman (Homo sapiens) [TaxId: 9606]view
CSL-type zinc finger-containing protein 3 (J-domain protein DjC7, 1700030a21RIK)Chaperone J-domainMouse (Mus musculus) [TaxId: 10090]view
automated matchesautomated matchesBaker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]view
Auxilin J-domainChaperone J-domainCow (Bos taurus) [TaxId: 9913]view
automated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesThale cress (Arabidopsis thaliana) [TaxId: 3702]view
automated matchesautomated matchesPlasmodium falciparum [TaxId: 36329]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150
M D R V L S R A D K E R L L E L L K L P R - - - - - - - - - - - - - - - - - - - - - - - Q L W G D F G R M Q Q A Y K Q Q S L L L H P D K - - - - - - G G S H A L M Q E L N S L W G T F K T E V Y - - - - - - - - - N L R M N L G G T G F - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Q
- - - - - - - - - - M D Y F T L F G L P A R Y - - - - - - - - - - - - - - - - - - - - - - - Q L D T Q A L S L R F Q D L Q R Q Y H P D K F - A S G S Q A E Q L A A V Q Q S A T I N Q A W Q T L R H - - - - - - P L M R A E Y L L S L H G - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - R E E S L Q L M D L L G L E R - - - - - - - - - - - - - - - - - - - - - - - S A W G N I P L M R K A Y L K K C K E F H P D K - - - - - - G G D E E K M K K M N T L Y K K M E D G V K Y A H Q P D F G G - - - - - - - - - - F W D A T E I P T Y G T D E W E Q W W N A F N E E N L F C S E E M P S S D D E A T
- - - - - I L K E V T S V V E Q A W K L P E - - - - - - - - - - - - - - - - - - - - - - - - - - - - S E R K K I I R R L Y L K W H P D K N P E - - - N - - H D I A N E V F K H L Q N E I N R L E K - - - - - - - - Q A F L D - - - - - - Q N A D R A S R R T F - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
M A L E Q T L K K - - D W Y S I L G A D P - - - - - - - - - - - - - - - - - - - - - - - - - S A N M S D L K Q K Y Q K L I L L Y H P D K Q S A D V P A G T M E E C M Q K F I E I D Q A W K I L G N - - - - - - E E T K K K Y D L Q R - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - M V K E T K L Y D L L G V S P - - - - - - - - - - - - - - - - - - - - - - - - - S A N E Q E L K K G Y R K A A L K Y H P D K P - - - - - - - - - T G D T E K F K E I S E A F E I L N D - - - - - - P Q K R E I Y D Q Y G L E A A R S G G P S F G P - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - D P E K L K I L E W I E G K E R N I R A L L S T M H T V L W A G E T K W K P V G M A D L V T P E Q V K K V Y R K A V L V V H P C K A T - - - - - G Q - - P Y E Q Y A K M I F M E L N D A W S - - - - - - - - E F E N Q - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
S - Q G D C S Y S R T A L Y D L L G V P S - - - - - - - - - - - - - - - - - - - - - - - - - T A T Q A Q I K A A Y Y R Q C F L Y H P D R N S - - - - - - G S A E A A E R F T R I S Q A Y V V L G S - - - - - - A T L R R K Y D R G L L S D E D L R G P G - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
E E I K N I D A K I R K W S S G K S G N I R S L L S T L Q Y I L W S G S - G W K P V P L M D M I E G N A V R K S Y Q R A L L I L H P D K L Q Q - - - K G A S A N Q K Y M A E K V F E L L Q E A W D - - - - - - - - H F N T L - - - - - - G P - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - M D Y Y T L L G V D K - - - - - - - - - - - - - - - - - - - - - - - - - G C S E D D L R R A Y L K L A M K W H P D K H - V N K - - G S K V E A E E K F K N I C E A Y S V L S D - - - - - - N E K R V K Y D L - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

 

 

 

 

 

Member Chain UniProtKB GO term
d1fpoa1 A P0A6L9 GO:0001671
d1fpoa1 A P0A6L9 GO:0005515
d1fpoa1 A P0A6L9 GO:0005829
d1fpoa1 A P0A6L9 GO:0006457
d1fpoa1 A P0A6L9 GO:0044571
d1fpoa1 A P0A6L9 GO:0051087
d1fpoa1 A P0A6L9 GO:0051259
d1fpoa1 A P0A6L9 GO:0097428
d1fpoa1 A P0A6L9 GO:1990230
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in