Superfamily : 418735 [ Perfringolysin N-terminal-like ]
Class : Membrane and cell surface proteins and peptides
Fold : Perfringolysin N-terminal-like
# of Members : 5
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1pfoa1  (  30 )    ditdknqsidsGIssLsYnrnevLasngdkies-fvpkegkkagnkfivV
d2qp2a1  (  11 )    eenserdvEirdrny---frklSlFdd-----------------------
d3hvna3  (  32 )           dinqyFqsLtyepqeiLtnegeyidn-ppattgmlengrfvvl
d6jmpa-  (   1 )       mankaVndfIlaMnydkkklLthqgesien-rfikegnqlpdeFVvI
d6nala1  (   2 )      gnnralindklaslqynpktvvfn-Gtsisnidlpaeerfddstyiv-
                            aaaaaa                          bb    bbb 

                             60        70        80        90        100 
d1pfoa1  (  79 )    erqkrslttspv--dIsIidsvndrTyPG-ALQLAdkaLv----enrpti
d2qp2a1  (  36 )    ------tVIagAEMIGTSYdVFgkYCnvGsCmnsLFdkInasednFkvti
d3hvna3  (  74 )    rrekknitnnsa--diaVIdakaanIyPG-ALLrAdqnLL----dnnPtl
d6jmpa-  (  47 )    erkkrslstnts--disVTatndsrLYPG-ALLVVdetLl----ennPtl
d6nala1  (  50 )    trekcsyeadf---diAvPsayedvtyPG-AllvAsndll----dgkPqe
                    bbbbbbbbb       b              bbb  aaaa          

                             110       120       130       140       150 
d1pfoa1  ( 122 )    LmvkRkpInInIdLpgLkg-ensikVddPtygkVsgAideLvskWnekys
d2qp2a1  (  84 )    gktlkVPyYIdCysvg-dlkytnAsge--sIesYQsnISskSrig-----
d3hvna3  ( 117 )    IsiaRgdLtLsLnLPglangdshtvVnsPtrstVrtgvnnLLskwnnty-
d6jmpa-  (  90 )    LavdRapmtYsIdLpglassdsflqVedPsnssVrgaVndlLakWhqdy-
d6nala1  (  92 )    lavdKdrvnitvdlpgat--disfkv-vPtfanvragindilskwFdshg
                           bbbbbb         bbbb    aaaaaaaaaaaaaaaa    

                             160       170       180       190       200 
d1pfoa1  ( 171 )    sth--tlpArtqysesmVysksQIssaLnVnakvLensLgVdfnAVanne
d2qp2a1  ( 127 )    ---------------------------nylFFSaSLkvDF-dtdsLtdfe
d3hvna3  ( 166 )    aGeygNtqAelqydetmAysmsQLkTkFgtsFekIavpLdInfdaVnsge
d6jmpa-  ( 139 )    -GqvnnVpA-mqhekitAhsmeQLkvkFgsdFekIGnsLdIdfnsVhsGe
d6nala1  ( 139 )    --gewslpAnFqyssslvydenEll-kFGCdisylkqklsidFsstraek
                               bbbbbb               aaaaaa    aaaaa   

                             210       220       230       240       250 
d1pfoa1  ( 219 )    kkVMILaykQiFYtVsAdlpknpsdLFdd-------sV-tFndLkqkgVs
d2qp2a1  ( 149 )    nAFSRIQyTydlYiLkss-aeaLkeFLkesVktaLdkAdteedMndLFn-
d3hvna3  ( 216 )    kqVQIVNfKQiYYtVsVdePespskLFg--------tt--vedLkrngIt
d6jmpa-  ( 188 )    kqIqIVnFkQiYYtVsVdavknPGdVFqd-------tV-tvedLrqrgIs
d6nala1  ( 187 )    ksvYliRFKqiFYsvsAerpakpAdiFae-------st-twedlaragis
                     bbbbbbbbbbbbbbbb                       aaaaaa    

                             260       270       280       290       300 
d1pfoa1  ( 261 )    neaPPLMVsnVaYGrtIyVKLeTt---sSsk-----dVqaAFkal--ikn
d2qp2a1  ( 197 )    -twGSHFLSGVVMGGCAqYSSSTnkytSnLtnsfdvVAaaSFagfIGlsa
d3hvna3  ( 258 )    devPPVYVssVsyGRSMFIKLeTs---srst-----qVqaaFkaA--Ikg
d6jmpa-  ( 230 )    aerPLVYIssVayGRQVYLKLETt---sKsd-----eveaAFesl--ikg
d6nala1  ( 229 )    eehPPlFvknvqyGRqiFlKFeSk---lsst-----elettikgtCskdG
                        bbbbbbbbbbbbbbbbbbb              aaaaaaaa     

                             310       320       330       340       350 
d1pfoa1  ( 301 )    tdikn--sqqykdIyenSsFtAVVlGGdaq------ehnkvvtk----dF
d2qp2a1  ( 246 )    rt-gnsfmeDikkFrsaSnikthaIGGdlsrfdPfggAtadpsaeiaaAk
d3hvna3  ( 298 )    vdisg--naeyqdILknTsFsAyiFGGdags-----aatvvsgn-----I
d6jmpa-  ( 270 )    vapq----tewkqIldnTeVkAVILgGdpss-----garvvtgk-----v
d6nala1  ( 271 )    lkidanasaalkeklsqidvsivvhgGs--------eavynglslnsddv
                             aaaaaaa bbbbbbbb               bbb      a

                             360       370       380       390       400 
d1pfoa1  ( 339 )    deIrkvikdnatFsTknpAyPiSYtSVFLkdnsvAavhnkTdyiettSte
d2qp2a1  ( 298 )    kaFedWkasVp-----napeLVNFAds-----------------------
d3hvna3  ( 336 )    etLkkiieegarygkLnlgvpISYsTnFVkdnrpAqilsnSeyieTtstv
d6jmpa-  ( 306 )    dmVedLiqegsrFtAdhpGlpIsYtTSFLrdnvvAtfqnsTdyveTkVta
d6nala1  ( 314 )    qkinriiwdntllSrtntAaplnYytvFlkdgvsagvhGtteyvaekter
                    aaaaaaaa           bbbbbbbbb          bbbbbbbbbbbb

                             410       420       430       440       450 
d1pfoa1  ( 389 )    ys                                                
d2qp2a1  ( 320 )    ----------------------nPLtGIWeLCsd-----rtqkakLkkHF
d3hvna3  ( 386 )    hn                                                
d6jmpa-  ( 356 )    yrnGdLlLdHsGaYvAqYyItwdeLsYdhqGkevltpkawdrngqdlta-
d6nala1  ( 364 )    ys                                                
                    b                                                 

                             460       470       480       490       500 
d1pfoa1                                                               
d2qp2a1  ( 343 )    e-----tvwApaesakrrvh                              
d3hvna3                                                               
d6jmpa-  ( 405 )    hfttsipLkGn----VrnLsVkIrEcTglawewwrtVyektdLplvrkrt
d6nala1                                                               
                                                                      

                             510       
d1pfoa1                                
d2qp2a1                                
d3hvna3                                
d6jmpa-  ( 451 )    IsIwgttlypqvedkvend
d6nala1
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Perfringolysin N-terminal domainPerfringolysin N-terminal-likeClostridium perfringens 1 [TaxId: 1502]view
Plu-MACPFMembrane attack complex/perforin (MACPF) familyPhotorhabdus luminescens [TaxId: 141679]view
Suilysin N-terminal domainPerfringolysin N-terminal-likeStreptococcus suis 1 [TaxId: 391295]view
Pneumolysin N-terminal domainPerfringolysin N-terminal-likePneumococcus (Streptococcus pneumoniae) [TaxId: 1313]view
Desulfobulbus propionicus cytolysin N-terminal domainPerfringolysin N-terminal-likeDesulfobulbus propionicus (strain ATCC 33891 / DSM 2032 / 1pr3) [TaxId: 577650]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
D I T D K N Q S I D S G I S S L S Y N R N E V L A S N G D K I E S - F V P K E G K K A G N K F I V V E R Q K R S L T T S P V - - D I S I I D S V N D R T Y P G - A L Q L A D K A L V - - - - E N R P T I L M V K R K P I N I N I D L P G L K G - E N S I K V D D P T Y G K V S G A I D E L V S K W N E K Y S S T H - - T L P A R T Q Y S E S M V Y S K S Q I S S A L N V N A K V L E N S L G V D F N A V A N N E K K V M I L A Y K Q I F Y T V S A D L P K N P S D L F D D - - - - - - - S V - T F N D L K Q K G V S N E A P P L M V S N V A Y G R T I Y V K L E T T - - - S S S K - - - - - D V Q A A F K A L - - I K N T D I K N - - S Q Q Y K D I Y E N S S F T A V V L G G D A Q - - - - - - E H N K V V T K - - - - D F D E I R K V I K D N A T F S T K N P A Y P I S Y T S V F L K D N S V A A V H N K T D Y I E T T S T E Y S - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
E E N S E R D V E I R D R N Y - - - F R K L S L F D D - - - - - - - - - - - - - - - - - - - - - - - - - - - - - T V I A G A E M I G T S Y D V F G K Y C N V G S C M N S L F D K I N A S E D N F K V T I G K T L K V P Y Y I D C Y S V G - D L K Y T N A S G E - - S I E S Y Q S N I S S K S R I G - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - N Y L F F S A S L K V D F - D T D S L T D F E N A F S R I Q Y T Y D L Y I L K S S - A E A L K E F L K E S V K T A L D K A D T E E D M N D L F N - - T W G S H F L S G V V M G G C A Q Y S S S T N K Y T S N L T N S F D V V A A A S F A G F I G L S A R T - G N S F M E D I K K F R S A S N I K T H A I G G D L S R F D P F G G A T A D P S A E I A A A K K A F E D W K A S V P - - - - - N A P E L V N F A D S - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - N P L T G I W E L C S D - - - - - R T Q K A K L K K H F E - - - - - T V W A P A E S A K R R V H - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - D I N Q Y F Q S L T Y E P Q E I L T N E G E Y I D N - P P A T T G M L E N G R F V V L R R E K K N I T N N S A - - D I A V I D A K A A N I Y P G - A L L R A D Q N L L - - - - D N N P T L I S I A R G D L T L S L N L P G L A N G D S H T V V N S P T R S T V R T G V N N L L S K W N N T Y - A G E Y G N T Q A E L Q Y D E T M A Y S M S Q L K T K F G T S F E K I A V P L D I N F D A V N S G E K Q V Q I V N F K Q I Y Y T V S V D E P E S P S K L F G - - - - - - - - T T - - V E D L K R N G I T D E V P P V Y V S S V S Y G R S M F I K L E T S - - - S R S T - - - - - Q V Q A A F K A A - - I K G V D I S G - - N A E Y Q D I L K N T S F S A Y I F G G D A G S - - - - - A A T V V S G N - - - - - I E T L K K I I E E G A R Y G K L N L G V P I S Y S T N F V K D N R P A Q I L S N S E Y I E T T S T V H N - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - M A N K A V N D F I L A M N Y D K K K L L T H Q G E S I E N - R F I K E G N Q L P D E F V V I E R K K R S L S T N T S - - D I S V T A T N D S R L Y P G - A L L V V D E T L L - - - - E N N P T L L A V D R A P M T Y S I D L P G L A S S D S F L Q V E D P S N S S V R G A V N D L L A K W H Q D Y - - G Q V N N V P A - M Q H E K I T A H S M E Q L K V K F G S D F E K I G N S L D I D F N S V H S G E K Q I Q I V N F K Q I Y Y T V S V D A V K N P G D V F Q D - - - - - - - T V - T V E D L R Q R G I S A E R P L V Y I S S V A Y G R Q V Y L K L E T T - - - S K S D - - - - - E V E A A F E S L - - I K G V A P Q - - - - T E W K Q I L D N T E V K A V I L G G D P S S - - - - - G A R V V T G K - - - - - V D M V E D L I Q E G S R F T A D H P G L P I S Y T T S F L R D N V V A T F Q N S T D Y V E T K V T A Y R N G D L L L D H S G A Y V A Q Y Y I T W D E L S Y D H Q G K E V L T P K A W D R N G Q D L T A - H F T T S I P L K G N - - - - V R N L S V K I R E C T G L A W E W W R T V Y E K T D L P L V R K R T I S I W G T T L Y P Q V E D K V E N D
- - G N N R A L I N D K L A S L Q Y N P K T V V F N - G T S I S N I D L P A E E R F D D S T Y I V - T R E K C S Y E A D F - - - D I A V P S A Y E D V T Y P G - A L L V A S N D L L - - - - D G K P Q E L A V D K D R V N I T V D L P G A T - - D I S F K V - V P T F A N V R A G I N D I L S K W F D S H G - - G E W S L P A N F Q Y S S S L V Y D E N E L L - K F G C D I S Y L K Q K L S I D F S S T R A E K K S V Y L I R F K Q I F Y S V S A E R P A K P A D I F A E - - - - - - - S T - T W E D L A R A G I S E E H P P L F V K N V Q Y G R Q I F L K F E S K - - - L S S T - - - - - E L E T T I K G T C S K D G L K I D A N A S A A L K E K L S Q I D V S I V V H G G S - - - - - - - - E A V Y N G L S L N S D D V Q K I N R I I W D N T L L S R T N T A A P L N Y Y T V F L K D G V S A G V H G T T E Y V A E K T E R Y S - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

 

 

 

 

 

Member Chain UniProtKB GO term
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in