PASS2.8 - Home

solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x

beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x

hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x

                             10        20        30        40        50  
d4ogca4  ( 822 )         dgahtv-------npsklvshrLGd-GLtvqqIdRAct---paLw
d4oo8a4  (1103 )                                                      
d5axwa4  ( 782 )    elindtlysTrkdkgntliVnnLngLydndkLlinspekLlmyhhdpqTY
                                                                      

                             60        70        80        90        100 
d4ogca4  ( 857 )    cALtrekdfde--knGLparedRaIrvhgheikSsdyIqVFSkrkktdsd
d4oo8a4  (1103 )                                          ggfskesilpkr
d5axwa4  ( 838 )    qklklimeqygdekNplyyyetgnyt---kyskngpvikIkyyg------
                                                                      

                             110       120       130       140       150 
d4ogca4  ( 905 )    rdetpfGAiav-------gGFveigpsIhHARIyrveg--kpvyAlrVFt
d4oo8a4  (1115 )    n-----sLiarkwdpk---yGGfdsptvaySVLVvAvgslsvkeLlgIti
d5axwa4  ( 885 )    ---nLnahlditddypnsnkvVklslkpyRFDVyldn---gvykFVtVkn
                            bb           bb    bbbbbbbbb      bbbbbbb 

                             160       170       180       190       200 
d4ogca4  ( 949 )    hdLlsqr---hgdlfsavIppqsISRCaepkLrkAittgnAtylgwVvvg
d4oo8a4  (1169 )    merssFe-----------npidfLakgyk----------eVdliikLpky
d5axwa4  ( 931 )    ld----vikkyyeVnsayeaklkIsn-------------qAefiasFynn
                                                                bbb   

                             210       220       230       240       250 
d4ogca4  ( 997 )    dELeInVdsft--------------------------------------y
d4oo8a4  (1202 )    slFelengRkRmLasageLqKGnelalpsyvnFlylAshpnkqlveqhkh
d5axwa4  ( 970 )    dlIkIng-------------------------------------------
                     bbb                                              

                             260       270       280       290       300 
d4ogca4  (1010 )    aiGrFledfpnttrWrIcgYdt--ns-kltLkPivla-aeglnpssAVne
d4oo8a4  (1265 )    yldeIieqIsef--SrVIla--danld------kVlsaynkhpiAenIih
d5axwa4  ( 977 )    ------------elyrVigVnndlln-rIeVnmidityreyLenmndr--
                                                                      

                             310       320       330       340       350 
d4ogca4  (1057 )    IVel--------kGWrVain---vLTkvhPtVVrrdalgrpryssslptS
d4oo8a4  (1312 )    LftlTnlgapaafYfdttIrrytsteVldatLIhqsitgl------yetr
d5axwa4  (1013 )    ---p--------priiktIa---sT--qsIkkystdilgnlyevskpqii
                                                  bbb                 

                           
d4ogca4  (1098 )    wtIe   
d4oo8a4  (1360 )    idLsqlg
d5axwa4

Domains
Outliers

Domain ID	Name	Family	Source	STRING-DB
d4ogca4 # Domain Specific Files ATM file: Atomic coordinates by ASTRAL ATM2ALI file: Amino acid sequences by ATM2ALI SST file: Secondary structure by SSTRUC PSA file: solvent accessibility by PSA HBD file: Hydrogen bonds by HBOND PSE file: PyMol session file for conserved interactions PDBSUM1: Topological diagram d4ogca4 # Links to other databases and tools RCSB-PDB: Research Collaboratory for Structural Bioinformatics SCOP: Structural Classification of Proteins EBI: European Bioinformatics Institute HOMSTRAD: Homologous Structure Alignment Database DDBASE: Dial-Derived Domain Database CATH: Class Architecture Topology and Homologous sfily PALI: Phylogeny and ALIgnment of homologous protein structures MODBASE: A Database of Annotated Comparative Protein Structure Models 3Dee: A Database of Protein Domain Definition PQS: Protein Quaternary Structure Query Form at the EBI LPC/CSU: Ligand-Protein Contacts & Contacts of Structural LPFC: A Library of Protein Family Cores MMDB: Molecular Modelling DataBase,NCBI CE: Databases and Tools for 3-D Protein Structure Comparison and Alignment PDBSUM: Summaries and structural analyses of PDB data files Pfam: Protein families database of alignments and HMMs	CRISPR-associated endonuclease Cas9/Csn1, PI domain	CRISPR-associated endonuclease Cas9/Csn1, PAM-interacting (PI) domain	Actinomyces naeslundii [TaxId: 1115803]	view
d4oo8a4 # Domain Specific Files ATM file: Atomic coordinates by ASTRAL ATM2ALI file: Amino acid sequences by ATM2ALI SST file: Secondary structure by SSTRUC PSA file: solvent accessibility by PSA HBD file: Hydrogen bonds by HBOND PSE file: PyMol session file for conserved interactions PDBSUM1: Topological diagram d4oo8a4 # Links to other databases and tools RCSB-PDB: Research Collaboratory for Structural Bioinformatics SCOP: Structural Classification of Proteins EBI: European Bioinformatics Institute HOMSTRAD: Homologous Structure Alignment Database DDBASE: Dial-Derived Domain Database CATH: Class Architecture Topology and Homologous sfily PALI: Phylogeny and ALIgnment of homologous protein structures MODBASE: A Database of Annotated Comparative Protein Structure Models 3Dee: A Database of Protein Domain Definition PQS: Protein Quaternary Structure Query Form at the EBI LPC/CSU: Ligand-Protein Contacts & Contacts of Structural LPFC: A Library of Protein Family Cores MMDB: Molecular Modelling DataBase,NCBI CE: Databases and Tools for 3-D Protein Structure Comparison and Alignment PDBSUM: Summaries and structural analyses of PDB data files Pfam: Protein families database of alignments and HMMs	CRISPR-associated endonuclease Cas9/Csn1, PI domain	CRISPR-associated endonuclease Cas9/Csn1, PAM-interacting (PI) domain	Streptococcus pyogenes [TaxId: 301447]	view
d5axwa4 # Domain Specific Files ATM file: Atomic coordinates by ASTRAL ATM2ALI file: Amino acid sequences by ATM2ALI SST file: Secondary structure by SSTRUC PSA file: solvent accessibility by PSA HBD file: Hydrogen bonds by HBOND PSE file: PyMol session file for conserved interactions PDBSUM1: Topological diagram d5axwa4 # Links to other databases and tools RCSB-PDB: Research Collaboratory for Structural Bioinformatics SCOP: Structural Classification of Proteins EBI: European Bioinformatics Institute HOMSTRAD: Homologous Structure Alignment Database DDBASE: Dial-Derived Domain Database CATH: Class Architecture Topology and Homologous sfily PALI: Phylogeny and ALIgnment of homologous protein structures MODBASE: A Database of Annotated Comparative Protein Structure Models 3Dee: A Database of Protein Domain Definition PQS: Protein Quaternary Structure Query Form at the EBI LPC/CSU: Ligand-Protein Contacts & Contacts of Structural LPFC: A Library of Protein Family Cores MMDB: Molecular Modelling DataBase,NCBI CE: Databases and Tools for 3-D Protein Structure Comparison and Alignment PDBSUM: Summaries and structural analyses of PDB data files Pfam: Protein families database of alignments and HMMs	CRISPR-associated endonuclease Cas9/Csn1, PI domain	CRISPR-associated endonuclease Cas9/Csn1, PAM-interacting (PI) domain	Staphylococcus aureus subsp. aureus [TaxId: 46170]	view

No outliers

Feature	Download
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

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E	L	I	N	D	T	L	Y	S	T	R	K	D	K	G	N	T	L	I	V	N	N	L	N	G	L	Y	D	N	D	K	L	L	I	N	S	P	E	K	L	L	M	Y	H	H	D	P	Q	T	Y	Q	K	L	K	L	I	M	E	Q	Y	G	D	E	K	N	P	L	Y	Y	Y	E	T	G	N	Y	T	-	-	-	K	Y	S	K	N	G	P	V	I	K	I	K	Y	Y	G	-	-	-	-	-	-	-	-	-	N	L	N	A	H	L	D	I	T	D	D	Y	P	N	S	N	K	V	V	K	L	S	L	K	P	Y	R	F	D	V	Y	L	D	N	-	-	-	G	V	Y	K	F	V	T	V	K	N	L	D	-	-	-	-	V	I	K	K	Y	Y	E	V	N	S	A	Y	E	A	K	L	K	I	S	N	-	-	-	-	-	-	-	-	-	-	-	-	-	Q	A	E	F	I	A	S	F	Y	N	N	D	L	I	K	I	N	G	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	E	L	Y	R	V	I	G	V	N	N	D	L	L	N	-	R	I	E	V	N	M	I	D	I	T	Y	R	E	Y	L	E	N	M	N	D	R	-	-	-	-	-	P	-	-	-	-	-	-	-	-	P	R	I	I	K	T	I	A	-	-	-	S	T	-	-	Q	S	I	K	K	Y	S	T	D	I	L	G	N	L	Y	E	V	S	K	P	Q	I	I	-	-	-	-	-	-	-

Member	Chain	UniProtKB	GO term

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-	-	-	-	-	D	G	A	H	T	V	-	-	-	-	-	-	-	N	P	S	K	L	V	S	H	R	L	G	D	-	G	L	T	V	Q	Q	I	D	R	A	C	T	-	-	-	P	A	L	W	C	A	L	T	R	E	K	D	F	D	E	-	-	K	N	G	L	P	A	R	E	D	R	A	I	R	V	H	G	H	E	I	K	S	S	D	Y	I	Q	V	F	S	K	R	K	K	T	D	S	D	R	D	E	T	P	F	G	A	I	A	V	-	-	-	-	-	-	-	G	G	F	V	E	I	G	P	S	I	H	H	A	R	I	Y	R	V	E	G	-	-	K	P	V	Y	A	L	R	V	F	T	H	D	L	L	S	Q	R	-	-	-	H	G	D	L	F	S	A	V	I	P	P	Q	S	I	S	R	C	A	E	P	K	L	R	K	A	I	T	T	G	N	A	T	Y	L	G	W	V	V	V	G	D	E	L	E	I	N	V	D	S	F	T	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Y	A	I	G	R	F	L	E	D	F	P	N	T	T	R	W	R	I	C	G	Y	D	T	-	-	N	S	-	K	L	T	L	K	P	I	V	L	A	-	A	E	G	L	N	P	S	S	A	V	N	E	I	V	E	L	-	-	-	-	-	-	-	-	K	G	W	R	V	A	I	N	-	-	-	V	L	T	K	V	H	P	T	V	V	R	R	D	A	L	G	R	P	R	Y	S	S	S	L	P	T	S	W	T	I	E	-	-	-
-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	G	G	F	S	K	E	S	I	L	P	K	R	N	-	-	-	-	-	S	L	I	A	R	K	W	D	P	K	-	-	-	Y	G	G	F	D	S	P	T	V	A	Y	S	V	L	V	V	A	V	G	S	L	S	V	K	E	L	L	G	I	T	I	M	E	R	S	S	F	E	-	-	-	-	-	-	-	-	-	-	-	N	P	I	D	F	L	A	K	G	Y	K	-	-	-	-	-	-	-	-	-	-	E	V	D	L	I	I	K	L	P	K	Y	S	L	F	E	L	E	N	G	R	K	R	M	L	A	S	A	G	E	L	Q	K	G	N	E	L	A	L	P	S	Y	V	N	F	L	Y	L	A	S	H	P	N	K	Q	L	V	E	Q	H	K	H	Y	L	D	E	I	I	E	Q	I	S	E	F	-	-	S	R	V	I	L	A	-	-	D	A	N	L	D	-	-	-	-	-	-	K	V	L	S	A	Y	N	K	H	P	I	A	E	N	I	I	H	L	F	T	L	T	N	L	G	A	P	A	A	F	Y	F	D	T	T	I	R	R	Y	T	S	T	E	V	L	D	A	T	L	I	H	Q	S	I	T	G	L	-	-	-	-	-	-	Y	E	T	R	I	D	L	S	Q	L	G
E	L	I	N	D	T	L	Y	S	T	R	K	D	K	G	N	T	L	I	V	N	N	L	N	G	L	Y	D	N	D	K	L	L	I	N	S	P	E	K	L	L	M	Y	H	H	D	P	Q	T	Y	Q	K	L	K	L	I	M	E	Q	Y	G	D	E	K	N	P	L	Y	Y	Y	E	T	G	N	Y	T	-	-	-	K	Y	S	K	N	G	P	V	I	K	I	K	Y	Y	G	-	-	-	-	-	-	-	-	-	N	L	N	A	H	L	D	I	T	D	D	Y	P	N	S	N	K	V	V	K	L	S	L	K	P	Y	R	F	D	V	Y	L	D	N	-	-	-	G	V	Y	K	F	V	T	V	K	N	L	D	-	-	-	-	V	I	K	K	Y	Y	E	V	N	S	A	Y	E	A	K	L	K	I	S	N	-	-	-	-	-	-	-	-	-	-	-	-	-	Q	A	E	F	I	A	S	F	Y	N	N	D	L	I	K	I	N	G	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	E	L	Y	R	V	I	G	V	N	N	D	L	L	N	-	R	I	E	V	N	M	I	D	I	T	Y	R	E	Y	L	E	N	M	N	D	R	-	-	-	-	-	P	-	-	-	-	-	-	-	-	P	R	I	I	K	T	I	A	-	-	-	S	T	-	-	Q	S	I	K	K	Y	S	T	D	I	L	G	N	L	Y	E	V	S	K	P	Q	I	I	-	-	-	-	-	-	-

									10										20										30										40										50										60										70										80										90										100										110										120										130										140										150										160										170										180										190										200										210										220										230										240										250										260										270										280										290										300										310										320										330										340										350
-	-	-	-	-	D	G	A	H	T	V	-	-	-	-	-	-	-	N	P	S	K	L	V	S	H	R	L	G	D	-	G	L	T	V	Q	Q	I	D	R	A	C	T	-	-	-	P	A	L	W	C	A	L	T	R	E	K	D	F	D	E	-	-	K	N	G	L	P	A	R	E	D	R	A	I	R	V	H	G	H	E	I	K	S	S	D	Y	I	Q	V	F	S	K	R	K	K	T	D	S	D	R	D	E	T	P	F	G	A	I	A	V	-	-	-	-	-	-	-	G	G	F	V	E	I	G	P	S	I	H	H	A	R	I	Y	R	V	E	G	-	-	K	P	V	Y	A	L	R	V	F	T	H	D	L	L	S	Q	R	-	-	-	H	G	D	L	F	S	A	V	I	P	P	Q	S	I	S	R	C	A	E	P	K	L	R	K	A	I	T	T	G	N	A	T	Y	L	G	W	V	V	V	G	D	E	L	E	I	N	V	D	S	F	T	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Y	A	I	G	R	F	L	E	D	F	P	N	T	T	R	W	R	I	C	G	Y	D	T	-	-	N	S	-	K	L	T	L	K	P	I	V	L	A	-	A	E	G	L	N	P	S	S	A	V	N	E	I	V	E	L	-	-	-	-	-	-	-	-	K	G	W	R	V	A	I	N	-	-	-	V	L	T	K	V	H	P	T	V	V	R	R	D	A	L	G	R	P	R	Y	S	S	S	L	P	T	S	W	T	I	E	-	-	-
-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	G	G	F	S	K	E	S	I	L	P	K	R	N	-	-	-	-	-	S	L	I	A	R	K	W	D	P	K	-	-	-	Y	G	G	F	D	S	P	T	V	A	Y	S	V	L	V	V	A	V	G	S	L	S	V	K	E	L	L	G	I	T	I	M	E	R	S	S	F	E	-	-	-	-	-	-	-	-	-	-	-	N	P	I	D	F	L	A	K	G	Y	K	-	-	-	-	-	-	-	-	-	-	E	V	D	L	I	I	K	L	P	K	Y	S	L	F	E	L	E	N	G	R	K	R	M	L	A	S	A	G	E	L	Q	K	G	N	E	L	A	L	P	S	Y	V	N	F	L	Y	L	A	S	H	P	N	K	Q	L	V	E	Q	H	K	H	Y	L	D	E	I	I	E	Q	I	S	E	F	-	-	S	R	V	I	L	A	-	-	D	A	N	L	D	-	-	-	-	-	-	K	V	L	S	A	Y	N	K	H	P	I	A	E	N	I	I	H	L	F	T	L	T	N	L	G	A	P	A	A	F	Y	F	D	T	T	I	R	R	Y	T	S	T	E	V	L	D	A	T	L	I	H	Q	S	I	T	G	L	-	-	-	-	-	-	Y	E	T	R	I	D	L	S	Q	L	G
E	L	I	N	D	T	L	Y	S	T	R	K	D	K	G	N	T	L	I	V	N	N	L	N	G	L	Y	D	N	D	K	L	L	I	N	S	P	E	K	L	L	M	Y	H	H	D	P	Q	T	Y	Q	K	L	K	L	I	M	E	Q	Y	G	D	E	K	N	P	L	Y	Y	Y	E	T	G	N	Y	T	-	-	-	K	Y	S	K	N	G	P	V	I	K	I	K	Y	Y	G	-	-	-	-	-	-	-	-	-	N	L	N	A	H	L	D	I	T	D	D	Y	P	N	S	N	K	V	V	K	L	S	L	K	P	Y	R	F	D	V	Y	L	D	N	-	-	-	G	V	Y	K	F	V	T	V	K	N	L	D	-	-	-	-	V	I	K	K	Y	Y	E	V	N	S	A	Y	E	A	K	L	K	I	S	N	-	-	-	-	-	-	-	-	-	-	-	-	-	Q	A	E	F	I	A	S	F	Y	N	N	D	L	I	K	I	N	G	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	E	L	Y	R	V	I	G	V	N	N	D	L	L	N	-	R	I	E	V	N	M	I	D	I	T	Y	R	E	Y	L	E	N	M	N	D	R	-	-	-	-	-	P	-	-	-	-	-	-	-	-	P	R	I	I	K	T	I	A	-	-	-	S	T	-	-	Q	S	I	K	K	Y	S	T	D	I	L	G	N	L	Y	E	V	S	K	P	Q	I	I	-	-	-	-	-	-	-