Superfamily : 111331 [ NAD kinase/diacylglycerol kinase-like ]
Class : Multi-domain proteins (alpha and beta)
Fold : NAD kinase/diacylglycerol kinase-like
# of Members : 6
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1u0ta-  (   5 )        rsvlLVvhtg---rdatetArrVekvLgdnkIaLrvl---------
d1z0sa-  (   1 )        mrAAVVyktd-------ghVkrIeeALkrleVeVelfn--------
d2bona1  (   5 )        paSLLILng---kStdnlpLreaimlLreegmtIhvrvtwekgdaa
d2qv7a1  (   2 )       rkrArIIYnptsgkeqfkrelpdAlikLekagyeTsayatekigDAt
d3s40a-  (   3 )    ktkFekVLLIVnpkagqgdlhtNltkIvppLaaaFpdLhilhtkeqgdAt
d4wera1  (   2 )        kkAVLIvnpssggekakefetlAeekLkqlFdeVvvkqtekggdAe
                          bbbbb          aaaaaaaaaaa     bbbb         

                             60        70        80        90        100 
d1u0ta-  (  40 )    ----------scLVLVLggdgtFlrAAlArn-----asipVLGVNlgrig
d1z0sa-  (  32 )    qpseeLen--FdFIVSVGgdgTIlrILqkLk-----rCppIFGIntgrvG
d2bona1  (  48 )    ryVeeArkfgVaTVIAGGgdgTIneVStaLiqCegddiPALGILplgtan
d2qv7a1  (  49 )    lEAerAh-enYdVLIAAGgdgTLneVVnGIAekp--nrpkLGVIPG-tvn
d3s40a-  (  53 )    kyCqefAs-kVdLIIVFGgdgtvfeCTnGLAple--irptlAIIPGgtcn
d4wera1  (  48 )    qfAreAAeshfdSVFV-GgdgTvneGisGLAeqa--yrPkFGFfPlgtvn
                                bbbbb  aaaaaaaa aa          bbbb      

                             110       120       130       140       150 
d1u0ta-  ( 112 )    fLa--EaeaeaidaVLehVvaqdyrvedrLTLdVvVrqggrivnrgwALn
d1z0sa-  (  75 )    lLT--HaspenFeveLkkaVekf-everFPRVsCs------ampdvlALn
d2bona1  (  98 )    DFAtSVgIpealdkALklAIa--gdAiaIDMAqVnk--------qtcFIN
d2qv7a1  (  97 )    DFGraLhIpndi-gALdvIie--ghStkVDIGkn----------nryFIn
d3s40a-  ( 100 )    dFSrTlgVpqniaeAAklItk--ehvkpvDVAkAn---------gqhFLn
d4wera1  (  96 )    DlarALnlp-dpeeAIqqldl--ektsaLDVGkIn---------ddyF-n
                                aaaaaaa      bbbb  bbb            bb  

                             160       170       180       190       200 
d1u0ta-  ( 160 )    eVsLekgprl------------------gvlgVvVeidgrpvsafgCdGV
d1z0sa-  ( 116 )    EIAVlsrkpa------------------kmIdVaLrvdgvevdrIrCdGF
d2bona1  ( 138 )    MATGGFgtrialgsvsyIihgLMrMdtLqpdrCeIrGen-fhwqgdALVI
d2qv7a1  ( 136 )    lAAGgqltg----pfayigFeLp----qkavdLrIeydg-nvfqgeAllF
d3s40a-  ( 139 )    fWgIgg-----------yyls-----tietfpVkItydg-qvyedeAvlV
d4wera1  ( 135 )    vVaIgtiklgklayfisgala-----naqtypFhLsLdq-keqtieSStV
                    bbbb                          bbbbbbb   bbbbbbb bb

                             210       220       230       240       250 
d1u0ta-  ( 192 )    LVSTPtG--STa-yAfsagGpvlwpdleaILVVPnnAhal----------
d1z0sa-  ( 148 )    IVATQiG--Stg-yAfsagGpvvePyleCFILIPiapfrf----------
d2bona1  ( 197 )    GIG-NGrqagggQqLCp---nAlIndglLqLrIFtg--deIlpalvsTLk
d2qv7a1  ( 195 )    FLG-LTNsagfe-klVp---dAkLDdGyFTLIIVekSnlaelghI-tlas
d3s40a-  ( 199 )    -VG-NGeylGgipSfIP---nVkCddGtLDIFVVks---tGiqaFkdYig
d4wera1  ( 194 )    lVG-LTnSiggfetlLp---eAqvddgkLHLVYLkDqslwdAvkAvpdll
                    bbb                          bbbbb                

                             260       270       280       290       300 
d1u0ta-  ( 229 )    ----------fgrpmvtspeAtIAIeIeadghdAlVfCDgrremlIpagS
d1z0sa-  ( 185 )    ----------gwkpyvvsMerkIeViAe----kAiVvADgqksvdfd--g
d2bona1  ( 241 )    s--de--dnpnIiegaSs---wFdIqAp---hdItFnLdg---eplsg-q
d2qv7a1  ( 241 )    r--geHtkHpkViyekAk---aInIssf---td-LLNvDg---eyGgk-L
d3s40a-  ( 241 )    kklfedsnendIfhvkAk---sIhIeTe---eekeVdTd-----sslh-T
d4wera1  ( 240 )    kGVdqst--dnLvyltFk---egtIsLe-nqeeltTnvdg---degaa-L
                                  bbb     bbbbb       bbbb     bb     

                             310       320       330      
d1u0ta-  ( 269 )    rLeVtrcvtsVkWArldsapftdrlvrkfrlpvtgwrg
d1z0sa-  ( 219 )    eItIeksefpAvFFkne--kRfrnLfgkvrsi-----g
d2bona1  ( 277 )    nFhIeIlpaalrCrLpp--dCpLlr             
d2qv7a1  ( 279 )    panFlNlerhIdVFApndivNeeLi------nndhvnl
d3s40a-  ( 281 )    pCqIeLlqghFtIynpavv                   
d4wera1  ( 280 )    pItLkIlpkhLtVYcg                      
                     bbbbb    bbbb
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Inorganic polyphosphate/ATP-NAD kinase PpnKNAD kinase-likeMycobacterium tuberculosis [TaxId: 1773]view
Inorganic polyphosphate/ATP-NAD kinase PpnKNAD kinase-likeArchaeoglobus fulgidus [TaxId: 2234]view
Lipid kinase YegSDiacylglycerol kinase-likeEscherichia coli [TaxId: 562]view
Diacylglycerol kinase DgkBDiacylglycerol kinase-likeStaphylococcus aureus [TaxId: 1280]view
automated matchesautomated matchesBacillus anthracis [TaxId: 260799]view
automated matchesautomated matchesEnterococcus faecalis [TaxId: 226185]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330
- - - - R S V L L V V H T G - - - R D A T E T A R R V E K V L G D N K I A L R V L - - - - - - - - - - - - - - - - - - - S C L V L V L G G D G T F L R A A L A R N - - - - - A S I P V L G V N L G R I G F L A - - E A E A E A I D A V L E H V V A Q D Y R V E D R L T L D V V V R Q G G R I V N R G W A L N E V S L E K G P R L - - - - - - - - - - - - - - - - - - G V L G V V V E I D G R P V S A F G C D G V L V S T P T G - - S T A - Y A F S A G G P V L W P D L E A I L V V P N N A H A L - - - - - - - - - - - - - - - - - - - - F G R P M V T S P E A T I A I E I E A D G H D A L V F C D G R R E M L I P A G S R L E V T R C V T S V K W A R L D S A P F T D R L V R K F R L P V T G W R G
- - - - M R A A V V Y K T D - - - - - - - G H V K R I E E A L K R L E V E V E L F N - - - - - - - - Q P S E E L E N - - F D F I V S V G G D G T I L R I L Q K L K - - - - - R C P P I F G I N T G R V G L L T - - H A S P E N F E V E L K K A V E K F - E V E R F P R V S C S - - - - - - A M P D V L A L N E I A V L S R K P A - - - - - - - - - - - - - - - - - - K M I D V A L R V D G V E V D R I R C D G F I V A T Q I G - - S T G - Y A F S A G G P V V E P Y L E C F I L I P I A P F R F - - - - - - - - - - - - - - - - - - - - G W K P Y V V S M E R K I E V I A E - - - - K A I V V A D G Q K S V D F D - - G E I T I E K S E F P A V F F K N E - - K R F R N L F G K V R S I - - - - - G
- - - - P A S L L I L N G - - - K S T D N L P L R E A I M L L R E E G M T I H V R V T W E K G D A A R Y V E E A R K F G V A T V I A G G G D G T I N E V S T A L I Q C E G D D I P A L G I L P L G T A N D F A T S V G I P E A L D K A L K L A I A - - G D A I A I D M A Q V N K - - - - - - - - Q T C F I N M A T G G F G T R I A L G S V S Y I I H G L M R M D T L Q P D R C E I R G E N - F H W Q G D A L V I G I G - N G R Q A G G G Q Q L C P - - - N A L I N D G L L Q L R I F T G - - D E I L P A L V S T L K S - - D E - - D N P N I I E G A S S - - - W F D I Q A P - - - H D I T F N L D G - - - E P L S G - Q N F H I E I L P A A L R C R L P P - - D C P L L R - - - - - - - - - - - - -
- - - R K R A R I I Y N P T S G K E Q F K R E L P D A L I K L E K A G Y E T S A Y A T E K I G D A T L E A E R A H - E N Y D V L I A A G G D G T L N E V V N G I A E K P - - N R P K L G V I P G - T V N D F G R A L H I P N D I - G A L D V I I E - - G H S T K V D I G K N - - - - - - - - - - N R Y F I N L A A G G Q L T G - - - - P F A Y I G F E L P - - - - Q K A V D L R I E Y D G - N V F Q G E A L L F F L G - L T N S A G F E - K L V P - - - D A K L D D G Y F T L I I V E K S N L A E L G H I - T L A S R - - G E H T K H P K V I Y E K A K - - - A I N I S S F - - - T D - L L N V D G - - - E Y G G K - L P A N F L N L E R H I D V F A P N D I V N E E L I - - - - - - N N D H V N L
K T K F E K V L L I V N P K A G Q G D L H T N L T K I V P P L A A A F P D L H I L H T K E Q G D A T K Y C Q E F A S - K V D L I I V F G G D G T V F E C T N G L A P L E - - I R P T L A I I P G G T C N D F S R T L G V P Q N I A E A A K L I T K - - E H V K P V D V A K A N - - - - - - - - - G Q H F L N F W G I G G - - - - - - - - - - - Y Y L S - - - - - T I E T F P V K I T Y D G - Q V Y E D E A V L V - V G - N G E Y L G G I P S F I P - - - N V K C D D G T L D I F V V K S - - - T G I Q A F K D Y I G K K L F E D S N E N D I F H V K A K - - - S I H I E T E - - - E E K E V D T D - - - - - S S L H - T P C Q I E L L Q G H F T I Y N P A V V - - - - - - - - - - - - - - - - - - -
- - - - K K A V L I V N P S S G G E K A K E F E T L A E E K L K Q L F D E V V V K Q T E K G G D A E Q F A R E A A E S H F D S V F V - G G D G T V N E G I S G L A E Q A - - Y R P K F G F F P L G T V N D L A R A L N L P - D P E E A I Q Q L D L - - E K T S A L D V G K I N - - - - - - - - - D D Y F - N V V A I G T I K L G K L A Y F I S G A L A - - - - - N A Q T Y P F H L S L D Q - K E Q T I E S S T V L V G - L T N S I G G F E T L L P - - - E A Q V D D G K L H L V Y L K D Q S L W D A V K A V P D L L K G V D Q S T - - D N L V Y L T F K - - - E G T I S L E - N Q E E L T T N V D G - - - D E G A A - L P I T L K I L P K H L T V Y C G - - - - - - - - - - - - - - - - - - - - - -

 

 

 

 

 

Member Chain UniProtKB GO term
d1u0ta_ A P9WHV7 GO:0003951
d1u0ta_ A P9WHV7 GO:0005524
d1u0ta_ A P9WHV7 GO:0005737
d1u0ta_ A P9WHV7 GO:0006741
d1u0ta_ A P9WHV7 GO:0006797
d1u0ta_ A P9WHV7 GO:0016301
d1u0ta_ A P9WHV7 GO:0016310
d1u0ta_ A P9WHV7 GO:0019674
d1u0ta_ A P9WHV7 GO:0046872
d1u0ta_ A P9WHV7 GO:0051287
d2bona1 A P76407 GO:0000287
d2bona1 A P76407 GO:0001727
d2bona1 A P76407 GO:0005515
d2bona1 A P76407 GO:0005524
d2bona1 A P76407 GO:0005737
d2bona1 A P76407 GO:0008654
d2bona1 A P76407 GO:0016301
d2bona1 A P76407 GO:0016310
d2bona1 A P76407 GO:0046872
d2qv7a1 A Q6GFF9 GO:0004143
d2qv7a1 A Q6GFF9 GO:0005524
d2qv7a1 A Q6GFF9 GO:0005886
d2qv7a1 A Q6GFF9 GO:0008654
d2qv7a1 A Q6GFF9 GO:0016301
d2qv7a1 A Q6GFF9 GO:0016310
d2qv7a1 A Q6GFF9 GO:0042802
d2qv7a1 A Q6GFF9 GO:0046872
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in