Superfamily : 103190 [ Sensory domain-like ]
Class : Alpha and beta proteins (a+b)
Fold : Profilin-like
# of Members : 11
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1p0za1  (   6 )                     erlhyqvGqrAliqAmqISa----mpeLveAVq
d2basa2  ( 263 )                   kkletvyehseqFykrVhqAvtslrk-------nn
d2hjea-  (  52 )                skqqtsalIhniFdshFaaIqihHdsnSksevIrdFYt
d2p7ja1  ( 181 )                                                      
d2p7ja2  (   9 )        nnventakealhqlaytgreynniqdqIetiSdllghsqsLydylr
d3by8a-  (  46 )                     dmtrdglankAlavArtlad----speIrqGLq
d3c38a-  (  52 )                tsvqtsslIqslFdfrLaaLrihQdstAknasLInaLv
d3c8ca1  (  63 )           rsVsdsVdeiVdgvSktTaevIngrksiAqyATslIennpe--
d3li9a-  (  41 )           klayeksi-eAgnyAnqfdaq-eaNqaiArtlAct-aeyg---
d4xmra1  (  41 )    ftktslyesTlknqtdlLkvTqstVedfrstNqsfTraLekdIanlpyqs
d6py3a-  (  37 )        airedldnyLn-mGevtAdnIqtwLsgrillIenaAqnIai-pe--
                                      aaaaaaaaaaaaaaaaaaaaa   aa      

                             60        70        80        90        100 
d1p0za1  (  35 )    -----krdla-rIkalIdpmrsfsdAtYITVGda----------------
d2basa2  ( 291 )    lss-------dddfIkkLAeeLtdcSfrIYCdeeGdQltGNVfkqd----
d2hjea-  (  90 )    drdtdvLnffF--lsidqsd-pshtPeFRFLtdh----------------
d2p7ja1  ( 181 )    nys-------pv-----------rdfhielVkhkGfYiaSpd--------
d2p7ja2  (  55 )    epskanltiLenWssvArnq---kLYkqIRFLdt----------------
d3by8a-  (  75 )    -----kkpqeSgIqaiAeavrkrndLlFIVVTdm----------------
d3c38a-  (  90 )    srdssrLdefF--ssvdele-lsnaPdLrFISsh----------------
d3c8ca1  ( 105 )    -------pdnVrtiIsqplikn--tFllVGFGlek---------------
d3li9a-  (  81 )    ----sqdReeA-siIk-riLnenpqLiGVYLGYepd----aFDgrdknyi
d4xmra1  (  91 )    LiteenIinnVGpiLk-yyrhsi-nALNVYLGln----------------
d6py3a-  (  81 )    -------paaVaslLeqkalts--tFmaSylGda----------------
                                 aaa aaa       bbbbb                  

                             110       120       130       140       150 
d1p0za1  (  63 )    -------sGqrLYHvn--pdeigksmeg------gdsdeAlin------a
d2basa2  ( 331 )    gewiyqpeyae---------knwswrp--------yflenirr---nlrk
d2hjea-  ( 121 )    -------k-giiWddg-nAhfygVn-------dl-iLdsLanrVs--fsn
d2p7ja1  ( 205 )    ------esrlyGdiipersqfnFsnyp--------dIwprVvs---eqag
d2p7ja2  (  87 )    -------sGtEkVrIkydfktiAgpslilrdksareYFkyAqsLdneqis
d3by8a-  ( 104 )    -------qslRYSHpe--aqrigqpFkg------ddIlkAl-n------g
d3c38a-  ( 121 )    -------d-nilwddg-nAsfygIa-------qq-eLnkLirrVa--isg
d3c8ca1  ( 131 )    -------dGs-nInNdp--s---wnpgptwdPrvrpWYkdAknag----k
d3li9a-  ( 122 )    napghdstGrFVPyCNkIng--pviieplvhydssdyYqlPkttg----k
d4xmra1  ( 123 )    -------ngk-VLLSqk--s--mpelrddldIktkdwYqeAlktn----d
d6py3a-  ( 106 )    -------tgh-ftirpd-------ampdgfdPrvrpWykgAesss----t
                                b                       aaaaaa        

                             160       170       180       190       200 
d1p0za1  (  92 )    ksyvsvrkgs----lgsSLrGKSPIqd---atgkviGIVSVGyTi---eq
d2basa2  ( 363 )    GfFsdlysdletg----eIrtFsypdd---------qylfIDLpy---sy
d2hjea-  ( 152 )    nwyyinVmTsi----gsrhMLVRrVpIldpstgevlGfSFNAVVLDnnfa
d2p7ja1  ( 239 )    ysysg-------e----hlIaFsSikfvsn----eplHlIiDlsn---eq
d2p7ja2  ( 131 )    awgielErdkgelvyplspSlRILPisv---ndvrqGYlVLNVdi---ey
d3by8a-  ( 132 )    eenvainrgf----laqALRVFTPIyd---enhkqiGVVAIGlel---sr
d3c38a-  ( 152 )    nWhlvqTpseg----ksvhILMRrssLieag-gqvvGyLYVGIVLNdnfa
d3c8ca1  ( 164 )    lvITaPyadsasg----eiLVSVATpVkdsatgqflGSIFYDVsL---ae
d3li9a-  ( 166 )    dtltePyfye-------gifVSyDSPIfkn--gefAGIAGVdVpL---ey
d4xmra1  ( 161 )    IfvTpayldtvlk----qyVITYSkAIykd--gkiiGVLGVDIpS---ed
d6py3a-  ( 138 )    StLtePyidaatg----qtIISIAtaAa-----gsvgVVGGDLsl---qt
                      b               bbbbbbbb         bbbbbbbbb    aa

                             210       220       230       240       250 
d1p0za1  ( 132 )    le                                                
d2basa2  ( 400 )    Lyeqd-----------gLi                               
d2hjea-  ( 198 )    LMekLkseSnVd--NVVLVAn-svpLAnSli-------gdepynvadVlq
d2p7ja1  ( 271 )    lsk                                               
d2p7ja2  ( 176 )    Lssll                                             
d3by8a-  ( 172 )    Vtqqind                                           
d3c38a-  ( 198 )    LLenIrsgSnse--NLVLAvd-ttpLvsTLk-------gnepYsldyVVh
d3c8ca1  ( 207 )    LAelVnevklfdAgyVFIVsedgtTIAHp-kkefNg---------kps-e
d3li9a-  ( 205 )    vddvAssirtfdtGyAf-VSntGiFLShptqknwiGeksLsdfdveeikn
d4xmra1  ( 202 )    LqnlVaktp----gnTFLFdqknkifAAt-nkelln----psidhspvln
d6py3a-  ( 179 )    LintLsa----gmgyaFLVSadgkILVHp-dkalvm---------kslke
                    aaaa                                              

                             260       270       280       290       300 
d1p0za1                                                               
d2basa2                                                               
d2hjea-  ( 248 )    ---------------------llvietpIvvnavtteLcLlTVqd     
d2p7ja1                                                               
d2p7ja2                                                               
d3by8a-                                                               
d3c38a-  ( 238 )    sakdad--------------sfiVgqtfLeVesvptyLCVYsIqtn    
d3c8ca1  ( 247 )    fl-geskinvdthqvii-ngkpyAVSFsdVe---gedWyVGVVIdeeiAy
d3li9a-  ( 255 )    aAsdIreGigghveikdpitgktvIFYepvk---tgdfSFvlvvpkeel 
d4xmra1  ( 243 )    ayklngd--nnFFsykl-nneerLGAÇTkVf-----aytAÇITesAdiIn
d6py3a-  ( 219 )    AypqdtPissdfseVtv-dgktrIVNFtpIkgLpsvnWyIGlSVdkd-Af
                                                                      

                             
d1p0za1                      
d2basa2                      
d2hjea-                      
d2p7ja1                      
d2p7ja2                      
d3by8a-                      
d3c38a-                      
d3c8ca1  ( 292 )    aaldelrrs
d3li9a-                      
d4xmra1  ( 285 )    k        
d6py3a-  ( 269 )    s
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Sensor kinase CitASensory domain of two-component sensor kinaseKlebsiella pneumoniae [TaxId: 573]view
Hypothetical protein YkuI, C-terminal domainYkuI C-terminal domain-likeBacillus subtilis [TaxId: 1423]view
Autoinducer 2 sensor kinase/phosphatase LuxQLuxQ-periplasmic domain-likeVibrio harveyi [TaxId: 669]view
GGDEF family protein VP0354, C-terminal domainYkuI C-terminal domain-likeVibrio parahaemolyticus [TaxId: 670]view
GGDEF family protein VP0354, N-terminal domainYkuI C-terminal domain-likeVibrio parahaemolyticus [TaxId: 670]view
automated matchesSensory domain of two-component sensor kinaseEscherichia coli [TaxId: 562]view
Autoinducer 2 sensor kinase/phosphatase LuxQLuxQ-periplasmic domain-likeVibrio cholerae [TaxId: 666]view
VC_A0923Histidine kinase family 1 (HK1) sensor domainsVibrio cholerae [TaxId: 243277]view
MM_2955Histidine kinase family 1 (HK1) sensor domainsMethanosarcina mazei [TaxId: 2209]view
Cj1564Histidine kinase family 1 (HK1) sensor domainsCampylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168) [TaxId: 192222]view
automated matchesHistidine kinase family 1 (HK1) sensor domainsPseudomonas fluorescens [TaxId: 205922]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300
- - - - - - - - - - - - - - - - - E R L H Y Q V G Q R A L I Q A M Q I S A - - - - M P E L V E A V Q - - - - - K R D L A - R I K A L I D P M R S F S D A T Y I T V G D A - - - - - - - - - - - - - - - - - - - - - - - S G Q R L Y H V N - - P D E I G K S M E G - - - - - - G D S D E A L I N - - - - - - A K S Y V S V R K G S - - - - L G S S L R G K S P I Q D - - - A T G K V I G I V S V G Y T I - - - E Q L E - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - K K L E T V Y E H S E Q F Y K R V H Q A V T S L R K - - - - - - - N N L S S - - - - - - - D D D F I K K L A E E L T D C S F R I Y C D E E G D Q L T G N V F K Q D - - - - G E W I Y Q P E Y A E - - - - - - - - - K N W S W R P - - - - - - - - Y F L E N I R R - - - N L R K G F F S D L Y S D L E T G - - - - E I R T F S Y P D D - - - - - - - - - Q Y L F I D L P Y - - - S Y L Y E Q D - - - - - - - - - - - G L I - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - S K Q Q T S A L I H N I F D S H F A A I Q I H H D S N S K S E V I R D F Y T D R D T D V L N F F F - - L S I D Q S D - P S H T P E F R F L T D H - - - - - - - - - - - - - - - - - - - - - - - K - G I I W D D G - N A H F Y G V N - - - - - - - D L - I L D S L A N R V S - - F S N N W Y Y I N V M T S I - - - - G S R H M L V R R V P I L D P S T G E V L G F S F N A V V L D N N F A L M E K L K S E S N V D - - N V V L V A N - S V P L A N S L I - - - - - - - G D E P Y N V A D V L Q - - - - - - - - - - - - - - - - - - - - - L L V I E T P I V V N A V T T E L C L L T V Q D - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - N Y S - - - - - - - P V - - - - - - - - - - - R D F H I E L V K H K G F Y I A S P D - - - - - - - - - - - - - - E S R L Y G D I I P E R S Q F N F S N Y P - - - - - - - - D I W P R V V S - - - E Q A G Y S Y S G - - - - - - - E - - - - H L I A F S S I K F V S N - - - - E P L H L I I D L S N - - - E Q L S K - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - N N V E N T A K E A L H Q L A Y T G R E Y N N I Q D Q I E T I S D L L G H S Q S L Y D Y L R E P S K A N L T I L E N W S S V A R N Q - - - K L Y K Q I R F L D T - - - - - - - - - - - - - - - - - - - - - - - S G T E K V R I K Y D F K T I A G P S L I L R D K S A R E Y F K Y A Q S L D N E Q I S A W G I E L E R D K G E L V Y P L S P S L R I L P I S V - - - N D V R Q G Y L V L N V D I - - - E Y L S S L L - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - D M T R D G L A N K A L A V A R T L A D - - - - S P E I R Q G L Q - - - - - K K P Q E S G I Q A I A E A V R K R N D L L F I V V T D M - - - - - - - - - - - - - - - - - - - - - - - Q S L R Y S H P E - - A Q R I G Q P F K G - - - - - - D D I L K A L - N - - - - - - G E E N V A I N R G F - - - - L A Q A L R V F T P I Y D - - - E N H K Q I G V V A I G L E L - - - S R V T Q Q I N D - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - T S V Q T S S L I Q S L F D F R L A A L R I H Q D S T A K N A S L I N A L V S R D S S R L D E F F - - S S V D E L E - L S N A P D L R F I S S H - - - - - - - - - - - - - - - - - - - - - - - D - N I L W D D G - N A S F Y G I A - - - - - - - Q Q - E L N K L I R R V A - - I S G N W H L V Q T P S E G - - - - K S V H I L M R R S S L I E A G - G Q V V G Y L Y V G I V L N D N F A L L E N I R S G S N S E - - N L V L A V D - T T P L V S T L K - - - - - - - G N E P Y S L D Y V V H S A K D A D - - - - - - - - - - - - - - S F I V G Q T F L E V E S V P T Y L C V Y S I Q T N - - - - - - - - - - - - -
- - - - - - - R S V S D S V D E I V D G V S K T T A E V I N G R K S I A Q Y A T S L I E N N P E - - - - - - - - - P D N V R T I I S Q P L I K N - - T F L L V G F G L E K - - - - - - - - - - - - - - - - - - - - - - D G S - N I N N D P - - S - - - W N P G P T W D P R V R P W Y K D A K N A G - - - - K L V I T A P Y A D S A S G - - - - E I L V S V A T P V K D S A T G Q F L G S I F Y D V S L - - - A E L A E L V N E V K L F D A G Y V F I V S E D G T T I A H P - K K E F N G - - - - - - - - - K P S - E F L - G E S K I N V D T H Q V I I - N G K P Y A V S F S D V E - - - G E D W Y V G V V I D E E I A Y A A L D E L R R S
- - - - - - - K L A Y E K S I - E A G N Y A N Q F D A Q - E A N Q A I A R T L A C T - A E Y G - - - - - - - S Q D R E E A - S I I K - R I L N E N P Q L I G V Y L G Y E P D - - - - A F D G R D K N Y I N A P G H D S T G R F V P Y C N K I N G - - P V I I E P L V H Y D S S D Y Y Q L P K T T G - - - - K D T L T E P Y F Y E - - - - - - - G I F V S Y D S P I F K N - - G E F A G I A G V D V P L - - - E Y V D D V A S S I R T F D T G Y A F - V S N T G I F L S H P T Q K N W I G E K S L S D F D V E E I K N A A S D I R E G I G G H V E I K D P I T G K T V I F Y E P V K - - - T G D F S F V L V V P K E E L - - - - - - - - - -
F T K T S L Y E S T L K N Q T D L L K V T Q S T V E D F R S T N Q S F T R A L E K D I A N L P Y Q S L I T E E N I I N N V G P I L K - Y Y R H S I - N A L N V Y L G L N - - - - - - - - - - - - - - - - - - - - - - - N G K - V L L S Q K - - S - - M P E L R D D L D I K T K D W Y Q E A L K T N - - - - D I F V T P A Y L D T V L K - - - - Q Y V I T Y S K A I Y K D - - G K I I G V L G V D I P S - - - E D L Q N L V A K T P - - - - G N T F L F D Q K N K I F A A T - N K E L L N - - - - P S I D H S P V L N A Y K L N G D - - N N F F S Y K L - N N E E R L G A C T K V F - - - - - A Y T A C I T E S A D I I N K - - - - - - - -
- - - - A I R E D L D N Y L N - M G E V T A D N I Q T W L S G R I L L I E N A A Q N I A I - P E - - - - - - - - - P A A V A S L L E Q K A L T S - - T F M A S Y L G D A - - - - - - - - - - - - - - - - - - - - - - - T G H - F T I R P D - - - - - - - A M P D G F D P R V R P W Y K G A E S S S - - - - T S T L T E P Y I D A A T G - - - - Q T I I S I A T A A A - - - - - G S V G V V G G D L S L - - - Q T L I N T L S A - - - - G M G Y A F L V S A D G K I L V H P - D K A L V M - - - - - - - - - K S L K E A Y P Q D T P I S S D F S E V T V - D G K T R I V N F T P I K G L P S V N W Y I G L S V D K D - A F S - - - - - - - -

 

 

 

 

 

Member Chain UniProtKB GO term
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in