Superfamily : 102712 [ JAB1/MPN domain ]
Class : Alpha and beta proteins (a/b)
Fold : Cytidine deaminase-like
# of Members : 6
Superposed Structure
solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla
positive phi: italic x
 
                             10        20        30        40        50  
d1oi0a-  (   1 )                                    gssmkIsrgLLktIleaA
d2kcqa1  (   1 )                                       Mkttpdildqirvhg
d2znra1  ( 264 )    e------------------------------glrcVvLPedLchkFlqlA
d4ilgc-  (2148 )    sknewrksaiantlLylrlkniyvsaddfveeqnvYvLPknLLkkFIeIS
d5w83a-  (   3 )                                  lqHekvtiAplvllsAldHY
d5w83b-  (  24 )                                    ketvyissiAllkMlkhG
                                                        bb aaaaaaaaaaa

                             60        70        80        90        100 
d1oi0a-  (  19 )    ksahp---deFiAlLsGs-------kdvMdeLiflpfv------------
d2kcqa1  (  16 )    aday---peegcgfllGtvt--ddgdnrvaalhratnrrseqrtrryelt
d2znra1  ( 284 )    esntvrg-iETcGILCGklth---neFtIthVIVPkQsag-----pdyCd
d4ilgc-  (2198 )    Dv----k-iqVAAFIyGmsakdhpkvkeIkTVVLVPQlGh-----vgsVq
d5w83a-  (  23 )    ertqtkenkRcvGvilGdAn--ss-tirvtnSfalp----Feeeknsdvw
d5w83b-  (  42 )    ragv---pmevmGlMlGefv--ddytvnvvDvfaMp----qs--------
                    aa         bbbbbbb        bbbbbbb                 

                             110       120       130       140       150 
d1oi0a-  (  47 )    ------------si-----gmkvFGTVHShpspsÇrpseedlslFtr---
d2kcqa1  (  61 )    addyraAdaaAqeq-----gldvvGvYhshpdhpArPsatdleeAtfp--
d2znra1  ( 325 )    menveelfnvqdqh-----dLltLGwIHTHPtqtAfLssvdLhtHCsyql
d4ilgc-  (2238 )    ISniPdigdlpdTe-----gLelLGWIHTQteelkfMaaseVatHSkLFa
d5w83a-  (  67 )    fldhnyienmnemckkinakekliGWYHSGp----klrasDlkinelFkk
d5w83b-  (  82 )    avddvfqakmmdmlkqtgrdqmvvGWYHSHPgfgCwlssvDvntqksFeq
                                         bbbbbbbb         aaaaaaaaa   

                             160       170       180       190       200 
d1oi0a-  (  90 )    ----fgkyHIIVçypYd--enswkCYn----rkGe----------eveLe
d2kcqa1  ( 104 )    ----gftYvivsvr--dgapealtAwalapdrs-----------------
d2znra1  ( 370 )    -mlpEA-IAIVCS-pkh--k-dtgifrLt--naGmleVsackkkgfhpht
d4ilgc-  (2283 )    dkkrdCIDISIfStp-g--sVsLsAynLt--deGYqWGeenkdimnvlse
d5w83a-  ( 113 )    ytqnnPlllivdvkgv---glptdAyvAieqvdgt---------------
d5w83b-  ( 132 )    lns-rAvAvvvDPiqSvkgkvvidAFrli---------------------
                           bbbbb          bbbbbb                      

                             210       220       230       240       250 
d1oi0a-  ( 120 )    vv                                                
d2kcqa1  ( 131 )    ------eFhredivrpdpea------p                       
d2znra1  ( 412 )    k-eprLfsiCkhVlvkd-ikIivldlr                       
d4ilgc-  (2328 )    gfeptfSthA-qLllsdritGnfIIPsgnvWNytfmgtaFnqegdynFky
d5w83a-  ( 149 )    ----stektFlhlpCtieAe------eaeeigvehllrd           
d5w83b-  ( 160 )    -----dhyyslnidykt---------aketkmlmnlhkeqwq        
                           bb                                         

                             260    
d1oi0a-                             
d2kcqa1                             
d2znra1                             
d4ilgc-  (2377 )    giPleFynemHrpvhf
d5w83a-                             
d5w83b-
 

 

Domain IDNameFamilySourceDomainSTRING-DB
Hypothetical protein AF2198JAB1/MPN domainArchaeoglobus fulgidus [TaxId: 2234]view
SRU_2040JAB1/MPN domainSalinibacter ruber DSM 13855 [TaxId: 309807]view
automated matchesJAB1/MPN domainHuman (Homo sapiens) [TaxId: 9606]view
automated matchesautomated matchesBaker's yeast (Saccharomyces cerevisiae) [TaxId: 559292]view
Proteasome regulatory subunit Rpn8JAB1/MPN domainBaker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]view
Proteasome regulatory subunit Rpn11JAB1/MPN domainBaker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]view

 

No outliers

FeatureDownload
Superfamily
Distance Matrix
Conserved Interactions
Cusp Results
Alistat - Alignment Statistics
SMotif - Conserved Structural Motifs
MeanRMS
PCSSE Details
Absolutely Conserved Residues
Highly Conserved Residues

 

10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G S S M K I S R G L L K T I L E A A K S A H P - - - D E F I A L L S G S - - - - - - - K D V M D E L I F L P F V - - - - - - - - - - - - - - - - - - - - - - - - S I - - - - - G M K V F G T V H S H P S P S C R P S E E D L S L F T R - - - - - - - F G K Y H I I V C Y P Y D - - E N S W K C Y N - - - - R K G E - - - - - - - - - - E V E L E V V - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - M K T T P D I L D Q I R V H G A D A Y - - - P E E G C G F L L G T V T - - D D G D N R V A A L H R A T N R R S E Q R T R R Y E L T A D D Y R A A D A A A Q E Q - - - - - G L D V V G V Y H S H P D H P A R P S A T D L E E A T F P - - - - - - G F T Y V I V S V R - - D G A P E A L T A W A L A P D R S - - - - - - - - - - - - - - - - - - - - - - - E F H R E D I V R P D P E A - - - - - - P - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
E - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - G L R C V V L P E D L C H K F L Q L A E S N T V R G - I E T C G I L C G K L T H - - - N E F T I T H V I V P K Q S A G - - - - - P D Y C D M E N V E E L F N V Q D Q H - - - - - D L L T L G W I H T H P T Q T A F L S S V D L H T H C S Y Q L - M L P E A - I A I V C S - P K H - - K - D T G I F R L T - - N A G M L E V S A C K K K G F H P H T K - E P R L F S I C K H V L V K D - I K I I V L D L R - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
S K N E W R K S A I A N T L L Y L R L K N I Y V S A D D F V E E Q N V Y V L P K N L L K K F I E I S D V - - - - K - I Q V A A F I Y G M S A K D H P K V K E I K T V V L V P Q L G H - - - - - V G S V Q I S N I P D I G D L P D T E - - - - - G L E L L G W I H T Q T E E L K F M A A S E V A T H S K L F A D K K R D C I D I S I F S T P - G - - S V S L S A Y N L T - - D E G Y Q W G E E N K D I M N V L S E G F E P T F S T H A - Q L L L S D R I T G N F I I P S G N V W N Y T F M G T A F N Q E G D Y N F K Y G I P L E F Y N E M H R P V H F
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - L Q H E K V T I A P L V L L S A L D H Y E R T Q T K E N K R C V G V I L G D A N - - S S - T I R V T N S F A L P - - - - F E E E K N S D V W F L D H N Y I E N M N E M C K K I N A K E K L I G W Y H S G P - - - - K L R A S D L K I N E L F K K Y T Q N N P L L L I V D V K G V - - - G L P T D A Y V A I E Q V D G T - - - - - - - - - - - - - - - - - - - S T E K T F L H L P C T I E A E - - - - - - E A E E I G V E H L L R D - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - K E T V Y I S S I A L L K M L K H G R A G V - - - P M E V M G L M L G E F V - - D D Y T V N V V D V F A M P - - - - Q S - - - - - - - - A V D D V F Q A K M M D M L K Q T G R D Q M V V G W Y H S H P G F G C W L S S V D V N T Q K S F E Q L N S - R A V A V V V D P I Q S V K G K V V I D A F R L I - - - - - - - - - - - - - - - - - - - - - - - - - - D H Y Y S L N I D Y K T - - - - - - - - - A K E T K M L M N L H K E Q W Q - - - - - - - - - - - - - - - - - - - - - - - -

 

 

 

 

 

Member Chain UniProtKB GO term
d1oi0a_ A O28085 GO:0006508
d1oi0a_ A O28085 GO:0008237
d1oi0a_ A O28085 GO:0046872
 
Contact: Prof. R. Sowdhamini - mini@ncbs.res.in