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20-Hydroxyecdysone

PubChem CID: 5459840

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Compound Synonyms 20-HYDROXYECDYSONE, Ecdysterone, 5289-74-7, Crustecdysone, beta-Ecdysone, Isoinokosterone, Viticosterone, Commisterone, Crustecdyson, Ecdysteron, Ekdisten, Hydroxyecdysone, THE-7, Ecdysten, beta-ECDYSTERONE, 20-OH ecdysone, beta-Ecdisone, (2beta,3beta,5beta,22R)-2,3,14,20,22,25-hexahydroxycholest-7-en-6-one, (+)-Ecdysterone, BIO101, (+)-20-Hydroxyecdysone, .beta-Ecdysterone, 20-Hydroxyecdyson, UNII-779A7KPL0Y, 20 Hydroxyecdysone, 779A7KPL0Y, CHEBI:16587, BIO-101, 20-Hydroxy-a-ecdysone, 20-HYDROXY-.ALPHA.-ECDYSONE, MFCD00036740, NSC 629484, NSC-629484, Bio 101, BRN 1917578, AI3-44727, b-Ecdysone, CHEMBL224128, (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one, DTXSID5040388, 20-HYDROXYECDYSONE [MI], 20-HYDROXYECDYSONE [WHO-DD], Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2.beta.,3.beta.,5.beta.,22R)-, 20E, 20-E, 2-beta,3-beta,14,20,22,25-Hexahydroxy-5-beta-cholet-7-en-6-one, 2beta,3beta,14alpha,20,22R,25-hexahydroxy-5beta-cholest-7-en-6-one, 2beta,3beta,14alpha,20R,22R,25-hexahydroxy-5beta-cholest-7-en-6-one, Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2beta,3beta,5beta,22R)-, (2b,3b,5b,22R)-2,3,14,20,22,25-Hexahydroxycholest-7-en-6-one, (22R)-2beta,3beta,14alpha,20,22,25-hexahydroxy-5beta-cholest-7-en-6-one, 5-beta-Cholest-7-en-6-one, 2-beta,3-beta,14,20,22,25-hexahydroxy-, (22R)-, Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2-beta,3-beta,5-beta,22R)-, SMR000539832, Ecdystene, Sarconeos, b-Ecdysterone, beta-Ecydisone, 20-Hydroxyedysone, ?- Ecdysone, (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-((2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl)-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta(a)phenanthren-6-one, 20r-hydroxyecdysone, Crustecdysone (Standard), 2beta,3beta,14alpha,20beta,22,25-Hexahydroxy-7-cholesten-6-one, , A-ECDYSONE,2,3,14,20,22,25-HEXAHYDROXY-7-CHOLESTEN-6-ONE, 20-Hydroxy-I+--ecdysone, Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2b,3b,5b,22R)-, SCHEMBL22086, MLS001164644, MLS002207226, BIO 101 [WHO-DD], BIO-101 [WHO-DD], DTXCID3020388, GTPL11987, HY-N6979R, 20-HYDROXY-ALPHA-ECDYSONE, NKDFYOWSKOHCCO-YPVLXUMRSA-N, HMS2230L09, 3a,7,8-trihydroxy-9a,11a-dimethyl-1-(2,3,6-trihydroxy-6-methylheptan-2-yl)-1h,2h,3h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta(a)phenanthren-5-one, 3A,7,8-TRIHYDROXY-9A,11A-DIMETHYL-1-(2,3,6-TRIHYDROXY-6-METHYLHEPTAN-2-YL)-1H,2H,3H,5AH,6H,7H,8H,9H,9BH,10H,11H-CYCLOPENTA[A]PHENANTHREN-5-ONE, HY-N6979, Ecdysterone, (+)-20-Hydroxyecdysone, BDBM50326777, HB3718, LMST01010209, s2417, AKOS004120029, CCG-269554, FH10452, AC-19603, AC-34796, CS-0007134, NS00097285, 20-Hydroxyecdysone, >=93% (HPLC), powder, Q423338, (2Beta,3beta,5beta)-2,3,14,20,22,25-hexahydroxycholest-7-en-6-one, 2-beta,3-beta,14,20,22,25-Hexahydroxy-5-beta-cholet-7-en-6- one, 2beta,3beta,14alpha,20beta,22alpha,25-Hexahydroxycholest-7-en-6-one, (2alpha,3alpha,5alpha,22R)-2,3,14,20,22,25-hexahydroxycholest-7-en-6-one, Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2-beta,3-beta,5-beta,22R)-(9CI), (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-((2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl)-1,2,3,4,5,9,10,11,12,13,14,15,16,17-tetradecahydro-6H-cyclopenta[a]phenanthren-6-one, (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(1R,2R)-1,2,5-trihydroxy-1,5-dimethyl-hexyl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one, 2,3,14-Trihydroxy-10,13-dimethyl-17-(1,2,5-trihydroxy-1,5-dimethyl-hexyl)-1,2,3,4,5,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-6-one
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 138.0
Hydrogen Bond Donor Count 6.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CC2C3CCCC3CCC2C2CCCCC12
Np Classifier Class Ecdysteroids
Deep Smiles O[C@H]C[C@@]C)[C@@H]C[C@H]6O)))C=O)C=C[C@@H]6CC[C@][C@@]6O)CC[C@@H]5[C@][C@@H]CCCO)C)C))))O))O)C))))))C
Heavy Atom Count 34.0
Classyfire Class Steroids and steroid derivatives
Scaffold Graph Node Level OC1CC2C3CCCC3CCC2C2CCCCC12
Classyfire Subclass Bile acids, alcohols and derivatives
Isotope Atom Count 0.0
Molecular Complexity 869.0
Database Name cmaup_ingredients;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 10.0
Uniprot Id P34021, O18531, O00167, Q9UNA4, P08183, O75496, O42275, P81908, Q8MWR1, E5L6Y0, Q4W6C8, P20153, Q9Y6L6, Q9NPD5, P06276, n.a.
Iupac Name (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one
Prediction Hob 0.0
Class Steroids and steroid derivatives
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 0.5
Superclass Lipids and lipid-like molecules
Subclass Bile acids, alcohols and derivatives
Gsk 4 400 Rule False
Molecular Formula C27H44O7
Scaffold Graph Node Bond Level O=C1C=C2C3CCCC3CCC2C2CCCCC12
Prediction Swissadme 0.0
Inchi Key NKDFYOWSKOHCCO-YPVLXUMRSA-N
Silicos It Class Soluble
Fcsp3 0.8888888888888888
Logs -3.169
Rotatable Bond Count 5.0
State Solid
Logd 0.122
Synonyms 20-OH Ecdysone, beta-Ecdysone, beta-Ecdysterone, Ecdysterone, b-Ecdysone, Β-ecdysone, b-Ecdysterone, Β-ecdysterone, 20 Hydroxyecdysone, Beta Ecdysone, Crustecdysone, (2beta,3beta,5beta,22R)-2,3,14,20,22,25-Hexahydroxycholest-7-en-6-one, (2β,3β,5β,22R)-2,3,14,20,22,25-Hexahydroxycholest-7-en-6-one, (+)-20-Hydroxyecdysone, (+)-Ecdysterone, 20-Hydroxy-alpha-ecdysone, 20-Hydroxy-α-ecdysone, 20-Hydroxyecdysone, 20R-Hydroxyecdysone, 2beta,3beta,14alpha,20beta,22alpha,25-Hexahydroxycholest-7-en-6-one, 2β,3β,14α,20β,22α,25-Hexahydroxycholest-7-en-6-one, Commisterone, Crustecdyson, Ecdysten, Ecdysteron, Ekdisten, Polypodin A, Polypodin C, Polypodine A, Polypodine C, beta-Ecydisone, β-Ecydisone, 20-hydroxy ecdysone(β-ecdysone), 20-hydroxyecdysone, beta-ecdysone, commisterone, ecdysterone
Esol Class Soluble
Functional Groups CC(C)=CC(C)=O, CO
Compound Name 20-Hydroxyecdysone
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 480.309
Formal Charge 0.0
Monoisotopic Mass 480.309
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 480.6
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 10.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aliphatic homopolycyclic compounds
Lipinski Rule Of 5 True
Esol -2.7797804000000013
Inchi InChI=1S/C27H44O7/c1-23(2,32)9-8-22(31)26(5,33)21-7-11-27(34)16-12-18(28)17-13-19(29)20(30)14-24(17,3)15(16)6-10-25(21,27)4/h12,15,17,19-22,29-34H,6-11,13-14H2,1-5H3/t15-,17-,19+,20-,21-,22+,24+,25+,26+,27+/m0/s1
Smiles C[C@]12CC[C@H]3C(=CC(=O)[C@H]4[C@@]3(C[C@@H]([C@@H](C4)O)O)C)[C@@]1(CC[C@@H]2[C@](C)([C@@H](CCC(C)(C)O)O)O)O
Nring 4.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule False
Taxonomy Direct Parent Hydroxy bile acids, alcohols and derivatives
Np Classifier Superclass Steroids

  • 1. Outgoing r'ship FOUND_IN to/from Achyranthes Aspera (Plant) Rel Props:Reference:https://doi.org/10.1002/minf.201000163
  • 2. Outgoing r'ship FOUND_IN to/from Achyranthes Bidentata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Achyranthes Fauriei (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Achyranthes Japonica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Amischotolype Mollissima (Plant) Rel Props:Reference:ISBN:9770972795006; ISBN:9788185042114
  • 6. Outgoing r'ship FOUND_IN to/from Artemisia Lactiflora (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Asparagus Filicinus (Plant) Rel Props:Reference:ISBN:9788185042145
  • 8. Outgoing r'ship FOUND_IN to/from Attalea Excelsa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Boerhavia Diffusa (Plant) Rel Props:Reference:ISBN:9780387706375
  • 10. Outgoing r'ship FOUND_IN to/from Catalpa Ovata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Chenopodium Album (Plant) Rel Props:Reference:ISBN:9788172363130
  • 12. Outgoing r'ship FOUND_IN to/from Cistanche Mongolica (Plant) Rel Props:Reference:ISBN:9788172362089; ISBN:9788185042145
  • 13. Outgoing r'ship FOUND_IN to/from Cistanche Tubulosa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 14. Outgoing r'ship FOUND_IN to/from Citrus Hassaku (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 15. Outgoing r'ship FOUND_IN to/from Commiphora Myrrha (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 16. Outgoing r'ship FOUND_IN to/from Coutarea Latifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 17. Outgoing r'ship FOUND_IN to/from Crepidiastrum Sonchifolium (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 18. Outgoing r'ship FOUND_IN to/from Cyanotis Arachnoidea (Plant) Rel Props:Reference:ISBN:9788185042084
  • 19. Outgoing r'ship FOUND_IN to/from Cyanotis Vaga (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 20. Outgoing r'ship FOUND_IN to/from Cyathula Prostrata (Plant) Rel Props:Reference:ISBN:9788172360481
  • 21. Outgoing r'ship FOUND_IN to/from Diploclisia Glaucescens (Plant) Rel Props:Reference:ISBN:9788185042138
  • 22. Outgoing r'ship FOUND_IN to/from Dipsacus Asper (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 23. Outgoing r'ship FOUND_IN to/from Duguetia Calycina (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 24. Outgoing r'ship FOUND_IN to/from Dysphania Botrys (Plant) Rel Props:Source_db:npass_chem_all
  • 25. Outgoing r'ship FOUND_IN to/from Echinops Setifer (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 26. Outgoing r'ship FOUND_IN to/from Echinopsis Latifolius (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 27. Outgoing r'ship FOUND_IN to/from Eriosema Chinense (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 28. Outgoing r'ship FOUND_IN to/from Eriostemon Spicatus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 29. Outgoing r'ship FOUND_IN to/from Fibraurea Tinctoria (Plant) Rel Props:Reference:ISBN:9788172362300
  • 30. Outgoing r'ship FOUND_IN to/from Garcinia Pyrifera (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 31. Outgoing r'ship FOUND_IN to/from Gentiana Crassicaulis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 32. Outgoing r'ship FOUND_IN to/from Gentiana Dahurica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 33. Outgoing r'ship FOUND_IN to/from Gentiana Macrophylla (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 34. Outgoing r'ship FOUND_IN to/from Gentiana Straminea (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 35. Outgoing r'ship FOUND_IN to/from Geranium Thunbergii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 36. Outgoing r'ship FOUND_IN to/from Gomphrena Celosioides (Plant) Rel Props:Reference:ISBN:9788172360481
  • 37. Outgoing r'ship FOUND_IN to/from Gomphrena Serrata (Plant) Rel Props:Reference:ISBN:9788185042084
  • 38. Outgoing r'ship FOUND_IN to/from Greenwayodendron Oliveri (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 39. Outgoing r'ship FOUND_IN to/from Hemidesmus Indicus (Plant) Rel Props:Reference:ISBN:9788190648912
  • 40. Outgoing r'ship FOUND_IN to/from Hymenothrix Wislizenii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 41. Outgoing r'ship FOUND_IN to/from Jacaranda Chelonia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 42. Outgoing r'ship FOUND_IN to/from Lablab Purpureus (Plant) Rel Props:Source_db:npass_chem_all
  • 43. Outgoing r'ship FOUND_IN to/from Lemmaphyllum Microphyllum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 44. Outgoing r'ship FOUND_IN to/from Matteuccia Struthiopteris (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 45. Outgoing r'ship FOUND_IN to/from Melilotus Albus (Plant) Rel Props:Source_db:npass_chem_all
  • 46. Outgoing r'ship FOUND_IN to/from Myrtopsis Sellingii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 47. Outgoing r'ship FOUND_IN to/from Ophryosporus Floribundus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 48. Outgoing r'ship FOUND_IN to/from Osmunda Japonica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 49. Outgoing r'ship FOUND_IN to/from Parablechnum Minus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 50. Outgoing r'ship FOUND_IN to/from Paratinospora Sagittata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 51. Outgoing r'ship FOUND_IN to/from Paris Polyphylla (Plant) Rel Props:Source_db:npass_chem_all
  • 52. Outgoing r'ship FOUND_IN to/from Payena Lucida (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 53. Outgoing r'ship FOUND_IN to/from Phalaris Canariensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 54. Outgoing r'ship FOUND_IN to/from Pimpinella Heyneana (Plant) Rel Props:Source_db:npass_chem_all
  • 55. Outgoing r'ship FOUND_IN to/from Plumbagella Micrantha (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 56. Outgoing r'ship FOUND_IN to/from Polypodium Vulgare (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 57. Outgoing r'ship FOUND_IN to/from Populus Tremuloides (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 58. Outgoing r'ship FOUND_IN to/from Pteridium Aquilinum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 59. Outgoing r'ship FOUND_IN to/from Rhaponticum Uniflorum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 60. Outgoing r'ship FOUND_IN to/from Rhododendron Micranthum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 61. Outgoing r'ship FOUND_IN to/from Rivina Humilis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 62. Outgoing r'ship FOUND_IN to/from Samadera Indica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 63. Outgoing r'ship FOUND_IN to/from Sesuvium Portulacastrum (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/12713122
  • 64. Outgoing r'ship FOUND_IN to/from Sida Acuta (Plant) Rel Props:Reference:ISBN:9788185042084
  • 65. Outgoing r'ship FOUND_IN to/from Sida Cordifolia (Plant) Rel Props:Reference:ISBN:9788183602525
  • 66. Outgoing r'ship FOUND_IN to/from Silene Banksia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 67. Outgoing r'ship FOUND_IN to/from Silene Fortunei (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 68. Outgoing r'ship FOUND_IN to/from Spinacia Oleracea (Plant) Rel Props:Reference:ISBN:9788185042114
  • 69. Outgoing r'ship FOUND_IN to/from Strychnos Cathayensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 70. Outgoing r'ship FOUND_IN to/from Styrax Formosanus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 71. Outgoing r'ship FOUND_IN to/from Tanacetum Parthenifolium (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 72. Outgoing r'ship FOUND_IN to/from Taxus Baccata (Plant) Rel Props:Reference:ISBN:9788171360536
  • 73. Outgoing r'ship FOUND_IN to/from Tinospora Capillipes (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 74. Outgoing r'ship FOUND_IN to/from Trianthema Portulacastrum (Plant) Rel Props:Reference:ISBN:9780387706375; ISBN:9788172363130; ISBN:9788185042084
  • 75. Outgoing r'ship FOUND_IN to/from Trichocolea Tomentella (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 76. Outgoing r'ship FOUND_IN to/from Vaccaria Hispanica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 77. Outgoing r'ship FOUND_IN to/from Vicia Sativa (Plant) Rel Props:Source_db:npass_chem_all
  • 78. Outgoing r'ship FOUND_IN to/from Vigna Angularis (Plant) Rel Props:Source_db:npass_chem_all
  • 79. Outgoing r'ship FOUND_IN to/from Vinca Minor (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 80. Outgoing r'ship FOUND_IN to/from Vitex Pinnata (Plant) Rel Props:Reference:ISBN:9788172363093
  • 81. Outgoing r'ship FOUND_IN to/from Woodwardia Orientalis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all