Pfam Domains mapped on to the structure: 2Q3B

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00291	Pyridoxal-phosphate dependent enzyme	PF00291	PF00291

Conserved Domain Database Superfamily Annotations: 2Q3B

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2Q3B	107204	cd01561	CBS_like -	cl00342
2	2Q3B	212605	cl00342	Trp-synth-beta_II	superfamily - -
3	2Q3B	212605	cl00342	Trp-synth-beta_II	superfamily - -

Structural Details of PDB entry 2Q3B PDBid Chains Hinge Swapped Domain 2Q3B A,B A:258-263,B:258-263 A:264-300,B:264-300 Swapped-domain interface residues and interactions: Chains Residues A 105, 287, 295, 297, 298, 300, B 104, 105, 287, 295, 297, 298, Non-swapped-domain interface residues and interactions: Chains Residues A 1, 2, 3, 4, 5, 6, 7, 10, 15, 16, 17, 18, 20, 21, 31, 36, 37, 39, 41, 81, 84, 85, 86, 87, 101, 104, 107, 108, 109, 110, 165, 166, 167, 169, 256, 257, 259, 260, 261, 262, B 1, 2, 3, 4, 5, 6, 7, 10, 15, 16, 17, 18, 20, 21, 31, 36, 37, 39, 41, 81, 84, 85, 86, 87, 101, 107, 108, 109, 110, 165, 166, 167, 169, 256, 257, 259, 260, 261, 262,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2Q3B

B:2Q3B

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2Q3B.ali
atm file:	2Q3B.atm
cof file:	2Q3B.cof
hbd file:	2Q3B.hbd
html file:	2Q3B.html
pdb file:	2Q3B.pdb
ps file:	2Q3B.ps
psa file:	2Q3B.psa
rtf file:	2Q3B.rtf
sst file:	2Q3B.sst
tem file:	2Q3B.tem