3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1ZD2

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 P PF13419 Haloacid dehalogenase-like hydrolase PF13419 PF13419

2 P PF12695 Alpha/beta hydrolase family PF12695 PF12695

3 P PF12697 Alpha/beta hydrolase family PF12697 PF12697

4 P PF00561 alpha/beta hydrolase fold PF00561 PF00561

Conserved Domain Database Superfamily Annotations: 1ZD2

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1ZD2 119389 HAD_like N cl11391

2 1ZD2 212620 HAD_like superfamily N -

3 1ZD2 211462 Esterase_lipase superfamily NC -

4 1ZD2 211462 Esterase_lipase superfamily NC -

5 1ZD2 211462 Esterase_lipase superfamily NC -

6 1ZD2 211462 Esterase_lipase superfamily NC -

Structural Details of PDB entry 1ZD2

Structural Details of PDB entry 1ZD2

PDBid Chains Hinge Swapped Domain

1ZD2 A,P A:219-234,P:219-234 A:2-218,P:235-300

Swapped-domain interface residues and interactions:

Chains Residues
A 56, 57, 58, 59, 61, 62, 127, 128, 129, 133, 134, 136, 137, 138, 140, 141, 144, 155,

B 320, 325, 326, 347, 348, 349, 477, 480, 481, 484, 485,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 233, 234, 235, 236, 237, 238, 239, 240, 241, 252, 253, 254, 255, 285, 316, 320, 321, 322, 323, 324, 325, 326, 345, 346, 347, 348, 349, 477, 480, 481, 482, 484, 485, 547,

B 56, 57, 58, 59, 61, 62, 127, 128, 129, 133, 134, 136, 137, 138, 140, 141, 144, 155, 233, 234, 235, 236, 237, 238, 239, 240, 241, 252, 253, 254, 255, 285, 316, 321, 322, 323, 324, 345, 346, 482,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

P No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

B:1ZD2 P:1ZD2 A:1ZD2

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1ZD2.ali
atm file: 1ZD2.atm
cof file: 1ZD2.cof
hbd file: 1ZD2.hbd
html file: 1ZD2.html
pdb file: 1ZD2.pdb
ps file: 1ZD2.ps
psa file: 1ZD2.psa
rtf file: 1ZD2.rtf
sst file: 1ZD2.sst
tem file: 1ZD2.tem