3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1WA9

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF00989 PAS fold PF00989 PF00989

2 A PF00989 PAS fold PF00989 PF00989

3 A PF08447 PAS fold PF08447 PF08447

Gene Ontology Annotations: 1WA9

No. GO ID GO Description Linkout - AmiGO

1 GO:0005515 protein binding GO:0005515

Conserved Domain Database Superfamily Annotations: 1WA9

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1WA9 29035 cd00130 PAS - cl02459

2 1WA9 207601 cl02459 PAS superfamily - -

3 1WA9 207601 cl02459 PAS superfamily - -

4 1WA9 207601 cl02459 PAS superfamily - -

Structural Details of PDB entry 1WA9

Structural Details of PDB entry 1WA9

PDBid Chains Hinge Swapped Domain

1WA9 A,B A:375-379,B:375-379 A:235-374,B:235-374

Swapped-domain interface residues and interactions:

Chains Residues
A 237, 239, 241, 243, 246, 247, 248, 249, 250, 252, 253, 254, 255, 270, 275, 286, 287, 290, 291, 294, 308, 310, 341, 343, 345, 348, 350, 360, 361, 362, 365, 367, 369, 371, 449, 450, 451, 452, 453, 481, 482, 540, 544, 547, 548,

B 235, 246, 247, 248, 249, 250, 252, 267, 270, 271, 272, 273, 275, 286, 287, 290, 291, 294, 355, 356, 359, 360, 361, 362, 449, 450, 451, 452, 453, 481, 482, 540, 560, 564, 568, 571,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 446, 448, 478, 480, 484, 487, 488, 541, 542, 551, 552,

B 394, 478, 480, 484, 487, 488, 541, 542, 547, 550, 551, 553, 556, 557, 559, 563, 566, 567, 572,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1WA9 B:1WA9

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1WA9.ali
atm file: 1WA9.atm
cof file: 1WA9.cof
hbd file: 1WA9.hbd
html file: 1WA9.html
pdb file: 1WA9.pdb
ps file: 1WA9.ps
psa file: 1WA9.psa
rtf file: 1WA9.rtf
sst file: 1WA9.sst
tem file: 1WA9.tem