Pfam Domains mapped on to the structure: 1HZD

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00378	Enoyl-CoA hydratase/isomerase family	PF00378	PF00378

Conserved Domain Database Superfamily Annotations: 1HZD

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1HZD	119339	cd06558	crotonase-like -	cl15762
2	1HZD	210162	cl15762	crotonase-like	superfamily - -
3	1HZD	210162	cl15762	crotonase-like	superfamily - -

Structural Details of PDB entry 1HZD PDBid Chains Hinge Swapped Domain 1HZD A,C,B A:299-303,C:299-303,B:299-303 A:304-339,C:304-339,B:304-339 Swapped-domain interface residues and interactions: Chains Residues A 147, 151, 155, 159, 212, 213, 214, 215, 217, 219, 221, 222, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 321, 324, 325, 328, 336, 339, B 147, 151, 155, 159, 212, 213, 214, 215, 217, 219, 221, 222, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 321, 324, 325, 328, 334, 336, 339, C 151, 155, 159, 212, 213, 214, 215, 217, 219, 221, 222, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 321, 324, 325, 328, 334, 336, 339, D 307, 310, 311, 313, 314, E 307, 310, 311, 313, 314, F 307, 310, 311, 313, 314, Non-swapped-domain interface residues and interactions: Chains Residues A 143, 146, 154, 158, 162, 166, 174, 195, 196, 197, 210, 211, 223, 225, 226, 230, 231, 232, 234, 235, 237, 238, 239, 255, 256, 274, 277, 278, 281, 282, 285, 286, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, B 122, 143, 144, 146, 154, 158, 162, 166, 174, 195, 196, 197, 210, 211, 223, 225, 226, 230, 231, 232, 234, 235, 237, 238, 239, 255, 256, 274, 277, 278, 281, 282, 285, 286, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, C 120, 143, 146, 147, 152, 153, 154, 158, 162, 166, 174, 195, 196, 197, 210, 211, 223, 225, 226, 230, 231, 232, 234, 235, 237, 238, 239, 241, 255, 256, 274, 277, 278, 281, 282, 285, 286, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, D 122, 143, 146, 147, 151, 154, 155, 158, 159, 162, 166, 174, 195, 196, 197, 210, 211, 212, 213, 214, 215, 217, 219, 221, 222, 223, 225, 226, 230, 231, 232, 234, 235, 237, 238, 239, 255, 256, 274, 277, 278, 281, 282, 285, 286, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 308, 309, 312, 315, 316, 317, 321, 324, 325, 328, 334, 336, 339, E 143, 144, 146, 147, 151, 152, 153, 154, 155, 158, 159, 162, 166, 174, 195, 196, 197, 210, 211, 212, 213, 214, 215, 217, 219, 221, 222, 223, 225, 226, 230, 231, 232, 234, 235, 237, 238, 239, 241, 255, 256, 274, 277, 278, 281, 282, 285, 286, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 308, 309, 312, 315, 316, 317, 321, 324, 325, 328, 334, 336, 339, F 143, 144, 146, 147, 151, 154, 155, 158, 159, 162, 166, 174, 195, 196, 197, 210, 211, 212, 213, 214, 215, 217, 219, 221, 222, 223, 225, 226, 230, 231, 232, 234, 235, 237, 238, 239, 255, 256, 274, 277, 278, 281, 282, 285, 286, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 308, 309, 312, 315, 316, 317, 321, 324, 325, 328, 334, 336,

Swapped domains are represented using trasperent spheres. Non-swapped part is reprented using light color and cartoon reprentation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
C	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

3:1HZD

A:1HZD

F:1HZD

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1HZD.ali
atm file:	1HZD.atm
cof file:	1HZD.cof
hbd file:	1HZD.hbd
html file:	1HZD.html
pdb file:	1HZD.pdb
ps file:	1HZD.ps
psa file:	1HZD.psa
rtf file:	1HZD.rtf
sst file:	1HZD.sst
tem file:	1HZD.tem