FASSM Server:

FASSM [Function Association using Sequence and Structural Motifs] is an algorithm developed to detect remote homology. The method is especially useful to detect difficult relationships across protein famlies. It has been shown that FASSM can be used to assign function to sequence belong to difficult categories such as discontinuous domains, small domains and circular-permutations in domains. FASSM is demonstrated to perform accurate family associations at sequence identities as low as 15%. FASSM is now available as a web server, which can be used for function association of protein sequences using FASSM approach that used Best Representative PSSM profiles (BRPs) derived from 3PFDB database.

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Prof. R. Sowdhamini [mini@ncbs.res.in]
Khader Shameer