HEADER ENDOCYTOSIS/EXOCYTOSIS COMPND MOL_ID: 1; COMPND 2 MOLECULE: CLATHRIN COAT ASSEMBLY PROTEIN AP50; COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: RESIDUES 122-435; COMPND 5 SYNONYM: MU2 ADAPTIN OF AP2 ADAPTOR; COMPND 6 ENGINEERED: YES; COMPND 7 MOL_ID: 2; COMPND 8 MOLECULE: EPIDERMAL GROWTH FACTOR RECEPTOR; COMPND 9 CHAIN: P; COMPND 10 FRAGMENT: RESIDUES 998-1003; COMPND 11 SYNONYM: EGFR; COMPND 12 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: RATTUS NORVEGICUS; SOURCE 3 ORGANISM_COMMON: RAT; SOURCE 4 GENE: AP50; SOURCE 5 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 6 EXPRESSION_SYSTEM_COMMON: BACTERIA; SOURCE 7 EXPRESSION_SYSTEM_STRAIN: BL21(DE3); SOURCE 8 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 9 EXPRESSION_SYSTEM_PLASMID: PPROEX; SOURCE 10 MOL_ID: 2; SOURCE 11 SYNTHETIC: YES; SOURCE 12 OTHER_DETAILS: THE HEXAPEPTIDE OF EPIDERMAL GROWTH FACTOR SOURCE 13 RECEPTOR WAS CHEMICALLY SYNTHESIZED RESOLUTION SOURCE : APS AUTHOR Y.MODIS,W.BOLL,I.RAPOPORT,T.KIRCHHAUSEN RESOLUTION : MURSHUDOV,VAGIN,DODSON EXPDTA X-RAY DIFFRACTION JRNL AUTH Y.MODIS,W.BOLL,I.RAPOPORT,T.KIRCHHAUSEN JRNL TITL MU2 ADAPTIN SUBUNIT (AP50) OF AP2 CLATHRIN JRNL TITL 2 ADAPTOR, COMPLEXED WITH EGFR INTERNALIZATION JRNL TITL 3 PEPTIDE FYRALM AT 2.5 A RESOLUTION JRNL REF TO BE PUBLISHED JRNL REFN RESOLUTION 2.50 ANGSTROMS.
Sequence in PIR format:
>P1;1i31A structureX:1i31A: 159 :A: 435 :A:epidermal growth factor receptor:rattus norvegicus: 9.99: 9.99 IGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKI/KQSIAIDDCTFH QCVRLS/ERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTP LNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVR YLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC*
View SSTRUC file for 1i31A
Rasmol View of 1i31A