HEADER NUCLEAR PROTEIN COMPND MOL_ID: 1; COMPND 2 MOLECULE: NUCLEAR AUTOANTIGEN SP100-B; COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: RESIDUES 595-688; COMPND 5 SYNONYM: SAND DOMAIN, KDWK DOMAIN, SPECKLED 100 KDA, COMPND 6 NUCLEAR DOT-ASSOCIATED SP100 PROTEIN, LYSP100B; COMPND 7 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 5 EXPRESSION_SYSTEM_STRAIN: BL21; SOURCE 6 EXPRESSION_SYSTEM_VARIANT: DE3; SOURCE 7 EXPRESSION_SYSTEM_PLASMID: MODIFIED PET-24D; SOURCE 8 EXPRESSION_SYSTEM_GENE: EXPRESSED AS FUSION PROTEIN WITH SOURCE 9 N-TERMINAL 6-HISTIDINE TAG AND A TEV PROTEASE CLEAVAGE SITE AUTHOR M.J.BOTTOMLEY,Z.LIU,M.W.COLLARD,J.I.HUGGENVIK,T.J.GIBSON, AUTHOR 2 M.SATTLER RESOLUTION : BRUNGER,ADAMS,CLORE,DELANO,GROS, EXPDTA NMR, 10 STRUCTURES JRNL AUTH M.J.BOTTOMLEY,M.W.COLLARD,J.I.HUGGENVIK,Z.LIU, JRNL AUTH 2 T.J.GIBSON,M.SATTLER JRNL TITL THE SAND DOMAIN STRUCTURE DEFINES A NOVEL DNA JRNL TITL 2 BINDING FOLD IN TRANSCRIPTIONAL REGULATION JRNL REF NAT.STRUCT.BIOL. V. 8 626 2001 JRNL REFN ASTM NSBIEW US ISSN 1072-8368 RESOLUTION NOT APPLICABLE.

Sequence in PIR format:

>P1;1h5pA structureX:1h5pA: 594 :A: 688 :A:nuclear autoantigen sp100-b:homo sapiens: 9.99: 9.99 MDENINFKQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKWFTPREFEIEGDRGASKNWKLSIRCGGYTLKV LMENKFLPEPPSTRKKVTIK*

View SSTRUC file for 1h5pA

Rasmol View of 1h5pA