HEADER TRANSCRIPTION/DNA REVDAT 5 10-APR-00 1CF7 1 HEADER REMARK COMPND MOL_ID: 1; COMPND 2 MOLECULE: TRANSCRIPTION FACTOR E2F-4; COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: DNA-BINDING DOMAIN; COMPND 5 ENGINEERED: YES; COMPND 6 MOL_ID: 2; COMPND 7 MOLECULE: TRANSCRIPTION FACTOR DP-2; COMPND 8 CHAIN: B; COMPND 9 FRAGMENT: DNA-BINDING DOMAIN; COMPND 10 ENGINEERED: YES; COMPND 11 MOL_ID: 3; COMPND 12 MOLECULE: DNA (5'- COMPND 13 D(*AP*TP*TP*TP*TP*CP*GP*CP*GP*CP*GP*GP*TP*TP*TP*T)-3'); COMPND 14 CHAIN: C; COMPND 15 FRAGMENT: ADENOVIRUS TYPE 5 E2 PROMOTER E2F-BINDING SITE; COMPND 16 ENGINEERED: YES; COMPND 17 MOL_ID: 4; COMPND 18 MOLECULE: DNA (5'- COMPND 19 D(*TP*AP*AP*AP*AP*CP*CP*GP*CP*GP*CP*GP*AP*AP*AP*A)-3'); COMPND 20 CHAIN: D; COMPND 21 FRAGMENT: ADENOVIRUS TYPE 5 E2 PROMOTER E2F-BINDING SITE; COMPND 22 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 5 EXPRESSION_SYSTEM_CELL_LINE: BL21(DE3); SOURCE 6 EXPRESSION_SYSTEM_CELLULAR_LOCATION: CYTOPLASM; SOURCE 7 EXPRESSION_SYSTEM_PLASMID: PGEX-4T3; SOURCE 8 MOL_ID: 2; SOURCE 9 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 10 ORGANISM_COMMON: HUMAN; SOURCE 11 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 12 EXPRESSION_SYSTEM_CELL_LINE: BL21(DE3); SOURCE 13 EXPRESSION_SYSTEM_CELLULAR_LOCATION: CYTOPLASM; SOURCE 14 EXPRESSION_SYSTEM_PLASMID: PGEX-4T3; SOURCE 15 MOL_ID: 3; SOURCE 16 SYNTHETIC: YES; SOURCE 17 MOL_ID: 4; SOURCE 18 SYNTHETIC: YES RESOLUTION SOURCE : CHESS AUTHOR N.ZHENG,E.FRAENKEL,C.O.PABO,N.P.PAVLETICH RESOLUTION : BRUNGER,ADAMS,CLORE,DELANO,GROS,GROSSE- EXPDTA X-RAY DIFFRACTION REVDAT 4 27-MAR-00 1CF7 1 JRNL REVDAT 2 14-APR-99 1CF7 1 JRNL JRNL AUTH N.ZHENG,E.FRAENKEL,C.O.PABO,N.P.PAVLETICH JRNL TITL STRUCTURAL BASIS OF DNA RECOGNITION BY THE JRNL TITL 2 HETERODIMERIC CELL CYCLE TRANSCRIPTION FACTOR JRNL TITL 3 E2F-DP JRNL REF GENES DEV. V. 13 666 1999 JRNL REFN ASTM GEDEEP US ISSN 0890-9369 RESOLUTION 2.60 ANGSTROMS.

Sequence in PIR format:

>P1;1cf7A structureX:1cf7A: 16 :A: 82 :A:dna (5'-:homo sapiens: 9.99: 9.99 SRHEKSLGLLTTKFVSLLQEAKDGVLDLKLAADTLAVRQKRRIYDITNVLEGIGLIEKKSKNSIQWK*

View SSTRUC file for 1cf7A

Rasmol View of 1cf7A