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STIFDB - Entry Name : AT5G56290 | Stress Signals involved in |
STIFDB Provides Data in 2 levels:
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Gene Description : AT5G56290
Locus Identifier | Gene Model Name | Gene Model Description | Gene Model Type | AT5G56290 | AT5G56290.1 | Encodes the peroxisomal targeting signal type 1 receptor that facilitates peroxisomal protein translocation. It recognizes proteins with the PTS1 consensus sequence (tripeptide SKL or a conserved variant) at the extreme C terminus. The protein has several domains, including C-terminal tetratricopeptide repeat motifs which act in binding the C-terminal "SKL" targeting signal. The mechanism of transport has been worked out in other organisms: The receptor recognizes and binds cytosolic PTS1-containing proteins. The PEX5-PTS1 complex binds a PEX14/PEX13 receptor complex at the peroxisome membrane and is translocated into the peroxisome matrix in a process dependent on PEX2,PEX10, and PEX12. In the peroxisome matrix, PEX5 releases its cargo and is recycled to the cytosol in a process dependent on PEX1, PEX4, PEX6 and PEX22. It is also involved, in conjunction with PEX7, in PTS1- and PTS2-dependent peroxisomal protein import. RNAi experiments suggest that PEX5 is necessary for the maintenance of both glyoxysomal and leaf peroxisomal functions. | |
Gene Ontology Data from
TAIR
: AT5G56290
GO Category |
GO Annotation Type |
GO ID |
GO Evidence Type |
References |
Biological Process | protein targeting to peroxisome | GO:0006625 |
IGI | Publication:501714612|PMID:15548601 |
Molecular Function | protein binding | GO:0005515 |
IPI | Publication:501717822|PMID:16256065 |
Molecular Function | peroxisome matrix targeting signal-1 binding | GO:0005052 |
ISS | Communication:501714663 |
Biological Process | protein targeting to peroxisome | GO:0006625 |
ISS | Communication:501714663 |
Biological Process | response to auxin stimulus | GO:0009733 |
IMP | Publication:5909|PMID:11063705 |
Molecular Function | protein binding | GO:0005515 |
IPI | Publication:501681308|PMID:11978862 |
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Biological Process |
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Molecular Function |
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Cellular Compartment |
Click here for
Guide to GO Evidence Codes
Orthologs
Gene Id | Sorghum bicolor | Zea mays | Glycine Max
| AT5G56290 | Sb07g028340 | GRMZM2G080775 | -- |
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