Centaurea scoparia
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| Scientific Name | Centaurea scoparia |
|---|---|
| Database Name | cmaup_plants |
| Synonyms | Centaurea Scoparia |
| Ipni Id | 191546-1 |
| Plant Name | Centaurea Scoparia |
| Genus Tax Id | 41503 |
| Disease Name | Psoriatic arthritis, Pituitary gland disorder, Psoriasis, Dyspareunia, Endometriosis, Idiopathic inflammatory myopathy, Breast cancer, Multiple sclerosis, Solid tumour/cancer, Acquired prion disease, Female pelvic pain, Arteries/arterioles disorder, Prostate cancer, Metastatic tumour, Acne vulgaris, Vaginitis, Breast in situ carcinoma, Rheumatoid arthritis, Menstrual cycle bleeding disorder, Neuropathy, Cushing syndrome, Unspecified viral infection of unspecified site, Pancreatic cancer, Melanoma, Skeletal anomaly, Male infertility, Low bone mass disorder, Adrenal cancer, Irritable bowel syndrome, Hyper-lipoproteinaemia, Brain cancer, Female genital tract noninflammatory disorder, Oesophagitis, Diabetes mellitus, type unspecified, Menopausal disorder, Female infertility, Cerebral ischaemic stroke, Carcinosarcoma of uterus, Serous cystadenoma,borderline malignancy of ovary, Pheochromocytoma, Dengue fever, unspecified, Malignant neoplasms of biliary tract, distal bile duct, Hepatoblastoma, Leishmaniasis, Adenocarcinoma of stomach, Diffuse large B-cell lymphomas, Other specified malignant neoplasms of kidney, except renal pelvis, West Nile virus infection, Adenocarcinoma of pancreas, Mesothelioma of pleura, Tetralogy of Fallot, Melanoma of skin, Hepatocellular carcinoma of liver, Superficial ovarian endometriosis, Cytomegaloviral disease, Chikungunya virus disease, Dilated cardiomyopathy, Malignant neoplasms of thymus, Invasive carcinoma of breast, Heart failure, unspecified, Glioblastoma of brain, Germ cell tumour of testis, Carpal tunnel syndrome, Malignant neoplasms of adrenal gland |
| Genus Name | Centaurea |
| Disease Id | FA21, 5A60-5A61, EA90, GA12, GA10, 4A41, 2C60-2C6Y, 8A40, 2A00-2F9Z, 8.00E+01, GA34, BD52, 2C82, 2D50-2E2Z, ED80, GA02, 2.00E+65, FA20, GA20, 8C0Z, 5A70, 1D9Z, 2C10, 2C30, LD24, GB04, FB83, 2D11, DD91, 5C80, 2A00, GA1Y, DA24, 5A14, GA30, GA31, 8B11, 2C76.43, 2C73.4, XH3854, 1D2Z, 2C15, 2C12.01, 1F54, 2B72.0, 2A81, 2C90.Y, 1D46, 2C10.0, 2C26.0, LA88.2, 2C12.02, GA10.B4, 1D82, 1D40, BC43.0, 2C27, 2C61, BD1Z, 2A00.00, 2C80.2, 8C10.0 |
| Family Name | Asteraceae |
| Family Tax Id | 4210 |
- 1. (+/-)-Isopanduratin A1 (PubChem CID: 44444913)
- 2. (-)-Alpha-Pinene (PubChem CID: 440968)
- 3. (-)-Nicolaioidesin B (PubChem CID: 637029)
- 4. (1' R,2' S,6' R)-2-Hydroxyisopanduratin A (PubChem CID: 23656472)
- 5. (1r,3ar,5ar,5br,7as,9s,11ar,11br,13ar,13br)-3a,5a,5b,8,8,11a-Hexamethyl-1-Prop-1-En-2-Yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-Hexadecahydrocyclopenta[A]chrysen-9-Ol (PubChem CID: 7092625)
- 6. (1s,4ar,5s,7s,8s,8ar)-8-Benzoyloxy-7-Hydroxy-5-[(E)-5-Hydroxy-3-Methylpent-3-Enyl]-1,4a-Dimethyl-6-Methylidene-3,4,5,7,8,8a-Hexahydro-2h-Naphthalene-1-Carboxylic Acid (PubChem CID: 118707632)
- 7. (2,6-Dihydroxy-4-Methoxyphenyl)-[(1s,2r,6s)-3-Methyl-2-(3-Methylbut-2-Enyl)-6-Phenylcyclohex-3-En-1-Yl]methanone (PubChem CID: 25023021)
- 8. (2-Hydroxy-4,6-Dimethoxyphenyl)-[(1r,2s,6r)-3-Methyl-2-(3-Methylbut-2-Enyl)-6-Phenylcyclohex-3-En-1-Yl]methanone (PubChem CID: 44444916)
- 9. (2e,4e,8z,11z)-N-(2-Hydroxy-2-Methylpropyl)tetradeca-2,4,8,11-Tetraenamide (PubChem CID: 14135319)
- 10. (2r)-2-Methylbutanoic Acid (PubChem CID: 6950479)
- 11. (2r)-5,7-Dimethoxyflavanone (PubChem CID: 689012)
- 12. (2r)-8-Geranylpinostrobin (PubChem CID: 23656470)
- 13. (2r,3s,4s,5r,6r)-2-(Hydroxymethyl)-6-[(2r)-4-[(1s,4s,6r)-4-Hydroxy-2,2,6-Trimethylcyclohexyl]butan-2-Yl]oxyoxane-3,4,5-Triol (PubChem CID: 10384912)
- 14. (2r,3s,4s,5r,6r)-2-[[(2r,3r,4r)-3,4-Dihydroxy-4-(Hydroxymethyl)oxolan-2-Yl]oxymethyl]-6-[(E)-3-(4-Hydroxy-3,5-Dimethoxyphenyl)prop-2-Enoxy]oxane-3,4,5-Triol (PubChem CID: 11386564)
- 15. (2s)-5,7-Dihydroxy-8-[(2r)-5-Hydroxy-5-Methyl-2-Prop-1-En-2-Ylhexyl]-2-(2-Hydroxyphenyl)-2,3-Dihydrochromen-4-One (PubChem CID: 44563122)
- 16. (2s)-5,7-Dimethoxy-2-Phenyl-3,4-Dihydro-2h-1-Benzopyran-4-One (PubChem CID: 689011)
- 17. (2s)-6-[(2e)-3,7-Dimethylocta-2,6-Dienyl]-5,7-Dihydroxy-2-Phenyl-2,3-Dihydrochromen-4-One (PubChem CID: 44444915)
- 18. (2s)-6-Geranylpinostrobin (PubChem CID: 44444914)
- 19. (2s,4s,5s)-2-[2-(3,4-Dihydroxyphenyl)-7-Hydroxy-3-[(2s,5s)-3,4,5-Trihydroxy-6-(Hydroxymethyl)oxan-2-Yl]oxychromenylium-5-Yl]oxy-6-(Hydroxymethyl)oxane-3,4,5-Triol (PubChem CID: 44256718)
- 20. (2s,8s)-5-Hydroxy-2-Methyl-2-(4-Methylpent-3-Enyl)-8-Phenyl-7,8-Dihydropyrano[3,2-G]chromen-6-One (PubChem CID: 162981219)
- 21. (3s)-16,17-Didehydrofalcarinol (PubChem CID: 5469785)
- 22. (4ar,6ar,6ar,6br,8ar,10r,12ar,14br)-10-Acetyloxy-2,2,4a,6b,9,9,12a-Heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-Tetradecahydropicene-6a-Carboxylic Acid (PubChem CID: 21633161)
- 23. (6-Hydroxy-4-Methoxy-1-Benzofuran-7-Yl)-[(1r,2s,6r)-3-Methyl-2-(3-Methylbut-2-Enyl)-6-Phenylcyclohex-3-En-1-Yl]methanone (PubChem CID: 24864268)
- 24. (7-Hydroxy-5-Methoxy-2,2-Dimethylchromen-8-Yl)-[(1r,2s,6r)-3-Methyl-2-(3-Methylbut-2-Enyl)-6-Phenylcyclohex-3-En-1-Yl]methanone (PubChem CID: 24864269)
- 25. (E)-1-[(1r,4s,13r)-9-Hydroxy-1,5,5-Trimethyl-6,15-Dioxatetracyclo[9.3.1.04,13.07,12]pentadeca-7,9,11-Trien-8-Yl]-3-Phenylprop-2-En-1-One (PubChem CID: 101306880)
- 26. (E)-1-[(2r)-7-Hydroxy-5-Methoxy-2-Methyl-2-(4-Methylpent-3-Enyl)chromen-8-Yl]-3-Phenylprop-2-En-1-One (PubChem CID: 163004499)
- 27. (E)-1-[(2s)-5-Hydroxy-7-Methoxy-2-Methyl-2-(4-Methylpent-3-Enyl)chromen-6-Yl]-3-Phenylprop-2-En-1-One (PubChem CID: 154496269)
- 28. (E)-1-[3-[(2e)-3,7-Dimethylocta-2,6-Dienyl]-2,4-Dihydroxy-6-Methoxyphenyl]-3-Phenylprop-2-En-1-One (PubChem CID: 23656471)
- 29. (E)-2-Tridecyl-2-Heptadecenal (PubChem CID: 11122959)
- 30. (S)-2,3-Dihydro-5-Hydroxy-7-Methoxy-2-Phenyl-4-Benzopyrone (PubChem CID: 6950539)
- 31. 1,2,3-Tri-O-Galloyl-Beta-D-Glucose (PubChem CID: 5322038)
- 32. 1,2,6-Trigalloylglucose (PubChem CID: 440308)
- 33. 1-(2-Hydroxy-4,7-Dimethoxyphenanthren-1-Yl)-4-Methoxyphenanthrene-2,7-Diol (PubChem CID: 11533293)
- 34. 1-Hexanol (PubChem CID: 8103)
- 35. 1beta-Hydroxybufalin (PubChem CID: 10993111)
- 36. 2',4-Dihydroxy-4',6'-Dimethoxychalcone (PubChem CID: 6293081)
- 37. 2,4-Heptadienal (PubChem CID: 5283321)
- 38. 2,6-Dimethoxy-4-(2-Methoxyphenyl)phenol (PubChem CID: 44720381)
- 39. 2-(2,4-Dihydroxy-5-Prenylphenyl)-5,6-Methylenedioxybenzofuran (PubChem CID: 15953774)
- 40. 2-Acetylhydroquinone (PubChem CID: 10279)
- 41. 29-Nor-20-Oxolupeol (PubChem CID: 490365)
- 42. 2h-Pyran-3-Ol, 6-Ethenyltetrahydro-2,2,6-Trimethyl-, 3-Acetate, (3r,6r)-Rel- (PubChem CID: 21116838)
- 43. 3',4',5,7-Tetramethoxyflavone (PubChem CID: 631170)
- 44. 3,3'-Digalloylprocyanidin B2 (PubChem CID: 124016)
- 45. 3-Acetoxy-8(17),13e-Labdadien-15-Oic Acid (PubChem CID: 13858192)
- 46. 3-Hexenol (PubChem CID: 5281167)
- 47. 3-Hydroxy-3,4-Bis((4-Hydroxy-3-Methoxyphenyl)methyl)oxolan-2-One (PubChem CID: 321311)
- 48. 3-Methoxy-4-Hydroxy-Cinnamic Acid (PubChem CID: 709)
- 49. 3-Phenyl-1-(2,4,6-Trihydroxyphenyl)prop-2-En-1-One (PubChem CID: 460718)
- 50. 30-Hydroxylup-20(29)-En-3-One (PubChem CID: 15038289)
- 51. 3beta,22beta-Dihydroxyolean-12-En-29-Oic Acid (PubChem CID: 21603566)
- 52. 4,2',4'-Trihydroxy-6'-Methoxydihydrochalcone (PubChem CID: 42607705)
- 53. 4-[(1r,3as,4s,6as)-4-(1,3-Benzodioxol-5-Yl)tetrahydro-1h,3h-Furo[3,4-C]furan-1-Yl]-2-Methoxyphenol (PubChem CID: 44144290)
- 54. 4-Hydroxyacetophenone (PubChem CID: 7469)
- 55. 4-Hydroxypanduratin A (PubChem CID: 636530)
- 56. 4-Methylindeno[2,1-B]pyridin-9-One (PubChem CID: 14626439)
- 57. 4-Terpineol, (+)- (PubChem CID: 2724161)
- 58. 4-Vinylphenol (PubChem CID: 62453)
- 59. 4h-1-Benzopyran-4-One, 5-Hydroxy-3,7-Dimethoxy-2-Phenyl- (PubChem CID: 5748697)
- 60. 5,7-Dimethoxyflavone (PubChem CID: 88881)
- 61. 5-O-Methylnaringenin (PubChem CID: 182315)
- 62. 5-P-Coumaroylquinic Acid, (Z)- (PubChem CID: 90478782)
- 63. 6beta-Hydroxystigmast-4-En-3-One (PubChem CID: 9823926)
- 64. 7,8-Dihydro-5,6-Dehydrokawain (PubChem CID: 160673)
- 65. [(1r,2s,6r)-6-(4-Hydroxyphenyl)-3-Methyl-2-(3-Methylbut-2-Enyl)cyclohex-3-En-1-Yl]-(2,4,6-Trihydroxyphenyl)methanone (PubChem CID: 163049404)
- 66. [(2r)-7-Hydroxy-5-Methoxy-2-Methyl-2-(4-Methylpent-3-Enyl)chromen-8-Yl]-[(1r,2r,6s)-3-Methyl-2-(3-Methylbut-2-Enyl)-6-Phenylcyclohex-3-En-1-Yl]methanone (PubChem CID: 163083698)
- 67. [(2r)-7-Hydroxy-5-Methoxy-2-Methyl-2-(4-Methylpent-3-Enyl)chromen-8-Yl]-[(1r,2s,6r)-3-Methyl-2-(3-Methylbut-2-Enyl)-6-Phenylcyclohex-3-En-1-Yl]methanone (PubChem CID: 101855692)
- 68. [(2s)-7-Hydroxy-5-Methoxy-2-Methyl-2-(4-Methylpent-3-Enyl)chromen-8-Yl]-[(1r,2r,6s)-3-Methyl-2-(3-Methylbut-2-Enyl)-6-Phenylcyclohex-3-En-1-Yl]methanone (PubChem CID: 163083697)
- 69. [(2s)-7-Hydroxy-5-Methoxy-2-Methyl-2-(4-Methylpent-3-Enyl)chromen-8-Yl]-[(1r,2s,6r)-3-Methyl-2-(3-Methylbut-2-Enyl)-6-Phenylcyclohex-3-En-1-Yl]methanone (PubChem CID: 101855694)
- 70. Agmatine (PubChem CID: 199)
- 71. Alpha-Eudesmol (PubChem CID: 92762)
- 72. Alpha-Pinene (PubChem CID: 6654)
- 73. Alpha-Pinene, (+)- (PubChem CID: 82227)
- 74. Alpha-Tocopherol (PubChem CID: 14985)
- 75. Alpinetin (PubChem CID: 154279)
- 76. Alpinumisoflavone (PubChem CID: 5490139)
- 77. Altersolanol A (PubChem CID: 89644)
- 78. Anhydropisatin (PubChem CID: 11822566)
- 79. Anonaine (PubChem CID: 160597)
- 80. Apigenin 7,4'-Dimethyl Ether (PubChem CID: 5281601)
- 81. Apigenin Trimethyl Ether (PubChem CID: 79730)
- 82. Aromadendrin 7-Methyl Ether (PubChem CID: 181132)
- 83. Aspalathin (PubChem CID: 11282394)
- 84. Aucuparin (PubChem CID: 442508)
- 85. Avicularin (PubChem CID: 5490064)
- 86. Beilschmin A (PubChem CID: 22297613)
- 87. Benzaldehyde (PubChem CID: 240)
- 88. Beta-Ocimene, (3z)- (PubChem CID: 5320250)
- 89. Beta-Phenylethanol Beta-D-Rutinoside (PubChem CID: 11166301)
- 90. Beta-Pinene (PubChem CID: 14896)
- 91. Beta-Sitosterol (PubChem CID: 222284)
- 92. Blestriarene A (PubChem CID: 11317652)
- 93. Blestriarene B (PubChem CID: 442695)
- 94. Bornyl Acetate, (-)- (PubChem CID: 93009)
- 95. Bufalin (PubChem CID: 9547215)
- 96. Bufogenin B (PubChem CID: 12358889)
- 97. Bufotalin (PubChem CID: 12302120)
- 98. Bufotenin Oxide (PubChem CID: 3083669)
- 99. Cadalene (PubChem CID: 10225)
- 100. Campesterol (PubChem CID: 173183)
- 101. Cardamomin (PubChem CID: 641785)
- 102. Carvacrol (PubChem CID: 10364)
- 103. Carvone, (+)- (PubChem CID: 16724)
- 104. Caryophyllene (PubChem CID: 5281515)
- 105. Caryophyllene,alpha + Beta Mixt. (PubChem CID: 5354499)
- 106. Chavicol (PubChem CID: 68148)
- 107. Cholesterol (PubChem CID: 5997)
- 108. Chryseriol (PubChem CID: 5280666)
- 109. Clovanemagnolol (PubChem CID: 10323149)
- 110. Cochlioquinone B (PubChem CID: 182083)
- 111. Cynaropicrin (PubChem CID: 119093)
- 112. D-(-)-Fructose (PubChem CID: 5984)
- 113. Delta-Cadinol (PubChem CID: 3084311)
- 114. Demethoxyyangonin (PubChem CID: 5273621)
- 115. Diacetyl (PubChem CID: 650)
- 116. Epicatechin (PubChem CID: 72276)
- 117. Eschweilenol C (PubChem CID: 10026656)
- 118. Ethane (PubChem CID: 6324)
- 119. Eucalyptin (PubChem CID: 76573)
- 120. Eucalyptol (PubChem CID: 2758)
- 121. Formononetin (PubChem CID: 5280378)
- 122. Galangin 3,5,7-Trimethyl Ether (PubChem CID: 117900)
- 123. Gallocatechin (PubChem CID: 65084)
- 124. Gamabufotalin (PubChem CID: 259803)
- 125. Garbanzol (PubChem CID: 442410)
- 126. Geranyl-2,4-Dihydroxy-6-Phenethylbenzoate (PubChem CID: 23656469)
- 127. Helichrysetin (PubChem CID: 6253344)
- 128. Hexyl Benzoate (PubChem CID: 23235)
- 129. Histamine (PubChem CID: 774)
- 130. Homoveratrylamine (PubChem CID: 8421)
- 131. Honokiol (PubChem CID: 72303)
- 132. Hydroxy-Alpha-Sanshool (PubChem CID: 10084135)
- 133. Hydroxy-Gamma-Isosanshool (PubChem CID: 14135316)
- 134. Hyperoside (PubChem CID: 5281643)
- 135. Isoamylamine (PubChem CID: 7894)
- 136. Isoeugenol (PubChem CID: 853433)
- 137. Isopanduratin A (PubChem CID: 10069916)
- 138. Isoquercetin (PubChem CID: 5280804)
- 139. Jaceosidin (PubChem CID: 5379096)
- 140. Juglanin (PubChem CID: 5318717)
- 141. Kaempferol 3,7,4'-Trimethyl Ether (PubChem CID: 5468749)
- 142. Kalopanaxsaponin B (PubChem CID: 11491905)
- 143. Kealiinine A (PubChem CID: 9997944)
- 144. Kealiinine C (PubChem CID: 23248791)
- 145. Kuraidin (PubChem CID: 44428631)
- 146. Kurarinol (PubChem CID: 44563198)
- 147. Leachianone G (PubChem CID: 5275227)
- 148. Linalool, (+)- (PubChem CID: 67179)
- 149. Liriodenine (PubChem CID: 10144)
- 150. Lupalbigenin (PubChem CID: 10001388)
- 151. Luteolin-4'-O-Glucoside (PubChem CID: 5319116)
- 152. Lyclavatol (PubChem CID: 11633800)
- 153. Lycodine (PubChem CID: 5462443)
- 154. Lycopodine (PubChem CID: 5462445)
- 155. Maackiain (PubChem CID: 91510)
- 156. Magnocurarine (PubChem CID: 53266)
- 157. Manghaslin (PubChem CID: 11498684)
- 158. Melitensin (PubChem CID: 14162547)
- 159. Methyl (1r,2s,6r)-3-Methyl-2-(3-Methylbut-2-Enyl)-6-Phenylcyclohex-3-Ene-1-Carboxylate (PubChem CID: 24864449)
- 160. Methyl (1s,5r,6s)-4-Methyl-5-(3-Methylbut-2-Enyl)-6-Phenylcyclohex-3-Ene-1-Carboxylate (PubChem CID: 163040699)
- 161. Methyl 4-[(3s,5r,8r,9s,10s,13s)-3-Hydroxy-10,13-Dimethyl-2,3,4,5,6,7,8,9,11,12-Decahydro-1h-Cyclopenta[A]phenanthren-17-Yl]-4-Oxobutanoate (PubChem CID: 72701756)
- 162. Methylheptenone (PubChem CID: 9862)
- 163. Morolic Acid (PubChem CID: 489944)
- 164. Myricetin (PubChem CID: 5281672)
- 165. N-Trans-Feruloyltramine (PubChem CID: 5280537)
- 166. Neoruscogenin (PubChem CID: 9910474)
- 167. Nicotine (PubChem CID: 89594)
- 168. Nonanal (PubChem CID: 31289)
- 169. Octylaldehyde (PubChem CID: 454)
- 170. Onopordopicrin (PubChem CID: 6440861)
- 171. P-Anisaldehyde (PubChem CID: 31244)
- 172. P-Coumaric Acid (PubChem CID: 637542)
- 173. Palmitic Acid (PubChem CID: 985)
- 174. Panduratin A (PubChem CID: 6483648)
- 175. Panduratin C (PubChem CID: 6483647)
- 176. Paulownin (PubChem CID: 3084131)
- 177. Phloretin (PubChem CID: 4788)
- 178. Phlorizin (PubChem CID: 6072)
- 179. Pinocembrin (PubChem CID: 68071)
- 180. Pinostrobin (PubChem CID: 73201)
- 181. Pinosylvin Monomethyl Ether (PubChem CID: 5281719)
- 182. Pluviatilol (PubChem CID: 70695727)
- 183. Pratensein (PubChem CID: 5281803)
- 184. Procyanidin A2 (PubChem CID: 124025)
- 185. Procyanidin B3 (PubChem CID: 146798)
- 186. Pseudoisoeugenol 2-Methylbutanoate (PubChem CID: 14056365)
- 187. Putrescine (PubChem CID: 1045)
- 188. Quercetin 3-Arabinoside (PubChem CID: 10252339)
- 189. Quercetin 3-O-Robinobioside (PubChem CID: 10371536)
- 190. Quercetin Pentamethyl Ether (PubChem CID: 97332)
- 191. Regeol A (PubChem CID: 10694409)
- 192. Resacetophenone (PubChem CID: 6990)
- 193. Retene (PubChem CID: 10222)
- 194. Retusin (PubChem CID: 5352005)
- 195. Rhamnocitrin (PubChem CID: 5320946)
- 196. Ruscogenin (PubChem CID: 441893)
- 197. Rutin (PubChem CID: 5280805)
- 198. Safynol (PubChem CID: 6442707)
- 199. Sakuranetin (PubChem CID: 73571)
- 200. Serotonin (PubChem CID: 5202)
- 201. Sesamin, (-)- (PubChem CID: 382073)
- 202. Shanzhiside Methyl Ester (PubChem CID: 13892722)
- 203. Sophoranol (PubChem CID: 12442899)
- 204. Stigmasterol Glucoside (PubChem CID: 6602508)
- 205. Stylopine (PubChem CID: 440583)
- 206. Styrene (PubChem CID: 7501)
- 207. Tectochrysin (PubChem CID: 5281954)
- 208. Tetramethylkaempferol (PubChem CID: 631095)
- 209. Teuflin (PubChem CID: 13071598)
- 210. Tirotundin (PubChem CID: 9975297)
- 211. Trans,trans-1,3,11-Tridecatriene-5,7,9-Triyne (PubChem CID: 5322028)
- 212. Trans-2,cis-6-Nonadienal (PubChem CID: 643731)
- 213. Trans-3-Hexen-1-Ol (PubChem CID: 5284503)
- 214. Trans-Calamenene (PubChem CID: 6429022)
- 215. Tricetin (PubChem CID: 5281701)
- 216. Triptotriterpenic Acid A (PubChem CID: 21594203)
- 217. Verbascoside (PubChem CID: 5281800)
- 218. Wikstromol (PubChem CID: 479756)
- 219. Xanthohumol (PubChem CID: 639665)
Not listed in any formulations.