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CID 9977936

PubChem CID: 9977936

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Compound Synonyms Akuammiline, 1897-26-3, Methyl (1S,10S,12R,13E)-18-(acetyloxymethyl)-13-ethylidene-8,15-diazapentacyclo[10.5.1.01,9.02,7.010,15]octadeca-2,4,6,8-tetraene-18-carboxylate, FS-9433, DA-50298
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 68.2
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2CCC34CC1CC2C3CC1CCCCC14
Np Classifier Class Corynanthe type
Deep Smiles COC=O)CCOC=O)C))))[C@@H]C[C@H]C=Ncc[C@@]95CCN9C/C/%13=C/C))))))))cccc6
Heavy Atom Count 29.0
Classyfire Class Corynanthean-type alkaloids
Scaffold Graph Node Level CC1CN2CCC34CC1CC2C3NC1CCCCC14
Isotope Atom Count 0.0
Molecular Complexity 805.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 3.0
Iupac Name methyl (1S,10S,12R,13E)-18-(acetyloxymethyl)-13-ethylidene-8,15-diazapentacyclo[10.5.1.01,9.02,7.010,15]octadeca-2,4,6,8-tetraene-18-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.5
Gsk 4 400 Rule True
Molecular Formula C23H26N2O4
Scaffold Graph Node Bond Level C=C1CN2CCC34CC1CC2C3=Nc1ccccc14
Inchi Key QBHALCZZZWCCLV-CLNIADLISA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 5.0
Synonyms akuammiline
Esol Class Soluble
Functional Groups C/C=C(/C)C, CN(C)C, COC(C)=O, cN=C(C)C
Compound Name CID 9977936
Exact Mass 394.189
Formal Charge 0.0
Monoisotopic Mass 394.189
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 394.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C23H26N2O4/c1-4-15-12-25-10-9-22-16-7-5-6-8-18(16)24-20(22)19(25)11-17(15)23(22,21(27)28-3)13-29-14(2)26/h4-8,17,19H,9-13H2,1-3H3/b15-4-/t17-,19+,22-,23?/m1/s1
Smiles C/C=C\1/CN2CC[C@@]34C5=CC=CC=C5N=C3[C@@H]2C[C@H]1C4(COC(=O)C)C(=O)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Catharanthus Roseus (Plant) Rel Props:Reference:https://doi.org/10.1093/database/bav075