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Rhetsinine

PubChem CID: 99652

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Compound Synonyms Rhetsinine, 526-43-2, 2-[2-(methylamino)benzoyl]-4,9-dihydro-3H-pyrido[3,4-b]indol-1-one, YQ7LSR9JJA, CHEMBL508030, 1H-Pyrido(3,4-b)indol-1-one, 2,3,4,9-tetrahydro-2-(2-(methyamino)benzoyl)-, NSC-258315, 2-[2-(Methylamino)benzoyl]-3,4-dihydro-beta-carboline-1(2H)-one, 2-(2-(Methylamino)benzoyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one, NSC258315, NSC 258315, Spectrum_001552, SpecPlus_000722, UNII-YQ7LSR9JJA, Spectrum2_001661, Spectrum3_001649, Spectrum4_001894, Spectrum5_000548, BSPBio_003377, KBioGR_002453, KBioSS_002032, DivK1c_006818, SPECTRUM1504176, SPBio_001841, SCHEMBL14478778, KBio1_001762, KBio2_002032, KBio2_004600, KBio2_007168, KBio3_002597, DTXSID30200576, BDBM50292374, CCG-38771, 2,3,4,9-Tetrahydro-2-[2-(methylamino)benzoyl]-1H-pyrido[3,4-b]indol-1-one, NCGC00095696-01, NCGC00095696-02, SR-05000002580, SR-05000002580-1, BRD-K08814982-001-02-9, 1H-Pyrido[3, 2,3,4,9-tetrahydro-2-[2-(methylamino)benzoyl]-, 2-[2-(Methylamino)benzoyl]-2,3,4,9-tetrahydro-1H- pyrido[3,4-b]indol-1-one
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 65.2
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC(C1CCCCC1)C1CCC2C3CCCCC3CC2C1C
Np Classifier Class Carboline alkaloids
Deep Smiles CNcccccc6C=O)NCCccC6=O))[nH]cc5cccc6
Heavy Atom Count 24.0
Classyfire Class Indoles and derivatives
Scaffold Graph Node Level OC(C1CCCCC1)N1CCC2C3CCCCC3NC2C1O
Classyfire Subclass Pyridoindoles
Isotope Atom Count 0.0
Molecular Complexity 509.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P08908, P02545, B2RXH2, P55210, P00352, P02791, P15428, P29466, P08684, Q92830, Q9NUW8, Q9Y6L6, Q9NPD5
Iupac Name 2-[2-(methylamino)benzoyl]-4,9-dihydro-3H-pyrido[3,4-b]indol-1-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Target Id NPT92, NPT483, NPT48, NPT1226, NPT94, NPT151, NPT277, NPT109
Xlogp 3.9
Gsk 4 400 Rule True
Molecular Formula C19H17N3O2
Scaffold Graph Node Bond Level O=C(c1ccccc1)N1CCc2c([nH]c3ccccc23)C1=O
Prediction Swissadme 0.0
Inchi Key RAEOYMOPVHBBKE-UHFFFAOYSA-N
Silicos It Class Poorly soluble
Fcsp3 0.1578947368421052
Logs -5.103
Rotatable Bond Count 2.0
Logd 3.176
Synonyms rhetsinine, rhetsinine (hydroxyevodiamine)
Esol Class Moderately soluble
Functional Groups cC(=O)N(C)C(c)=O, cNC, c[nH]c
Compound Name Rhetsinine
Prediction Hob Swissadme 0.0
Exact Mass 319.132
Formal Charge 0.0
Monoisotopic Mass 319.132
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 319.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.510056799999999
Inchi InChI=1S/C19H17N3O2/c1-20-15-8-4-3-7-14(15)18(23)22-11-10-13-12-6-2-5-9-16(12)21-17(13)19(22)24/h2-9,20-21H,10-11H2,1H3
Smiles CNC1=CC=CC=C1C(=O)N2CCC3=C(C2=O)NC4=CC=CC=C34
Nring 4.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Euodia Bodinieri (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Euodia Officinalis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Euodia Ruticarpa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Tetradium Ruticarpum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Zanthoxylum Limonella (Plant) Rel Props:Reference:ISBN:9788172363093
  • 6. Outgoing r'ship FOUND_IN to/from Zanthoxylum Oxyphyllum (Plant) Rel Props:Reference:ISBN:9770972795006; ISBN:9788185042053
  • 7. Outgoing r'ship FOUND_IN to/from Zanthoxylum Rhetsa (Plant) Rel Props:Reference:ISBN:9788185042053; ISBN:9788185042145