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Ibogamine-18-carboxylic acid, 13-methoxy-, methyl ester

PubChem CID: 99199

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Compound Synonyms 596-54-3, (-)-Isovoacangine, NSC 195198, Ibogamine-18-carboxylic acid, 13-methoxy-, methyl ester, DTXSID601316325
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 54.6
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1C2CCC2CC3CCC2C1C3
Np Classifier Class Iboga type
Deep Smiles CC[C@H]C[C@H]CN[C@@H]6[C@]C6)C=O)OC)))c[nH]ccc5CC%10)))cccc6)OC
Heavy Atom Count 27.0
Classyfire Class Ibogan-type alkaloids
Scaffold Graph Node Level C1CCC2C(C1)NC1C2CCN2CC3CCC2C1C3
Isotope Atom Count 0.0
Molecular Complexity 598.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 4.0
Iupac Name methyl (1S,15R,17S,18S)-17-ethyl-6-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene-1-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 3.5
Gsk 4 400 Rule True
Molecular Formula C22H28N2O3
Scaffold Graph Node Bond Level c1ccc2c3c([nH]c2c1)C1CC2CCC1N(CC3)C2
Inchi Key FPUHKQMDWMVBRI-PHKAQXKASA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 4.0
Synonyms isovoacangine
Esol Class Moderately soluble
Functional Groups CN(C)C, COC(C)=O, cOC, c[nH]c
Compound Name Ibogamine-18-carboxylic acid, 13-methoxy-, methyl ester
Exact Mass 368.21
Formal Charge 0.0
Monoisotopic Mass 368.21
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 368.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C22H28N2O3/c1-4-14-9-13-11-22(21(25)27-3)19-17(7-8-24(12-13)20(14)22)16-6-5-15(26-2)10-18(16)23-19/h5-6,10,13-14,20,23H,4,7-9,11-12H2,1-3H3/t13-,14+,20+,22-/m1/s1
Smiles CC[C@H]1C[C@@H]2C[C@@]3([C@H]1N(C2)CCC4=C3NC5=C4C=CC(=C5)OC)C(=O)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids