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Camptothecin acetate

PubChem CID: 9886692

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Compound Synonyms camptothecin acetate, O-Acetylcamptothecin, UNII-1V364427UG, NSC 95382, 1V364427UG, O-ACETYLCAMPTOTHECINE, 20(S)-camptothecin acetate, 20-O-ACETYLCAMPTOTHECIN, CAMPTOTHECIN ACETATE [MI], CAMPTOTHECIN ACETATE, (+)-, NSC-95382, CAMPTOTHECINE, ACETATE (ESTER), 7688-64-4, (S)-4-(Acetyloxy)4-ethyl-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 1H-PYRANO(3',4':6,7)INDOLIZINO(1,2-B)QUINOLINE-3,14(4H,12H)-DIONE, 4-(ACETYLOXY)-4-ETHYL-, (4S)-, 1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-(acetyloxy)-4-ethyl-, (S)-, Camptothecin-20(S)-acetate, ((19S)-19-ethyl-14,18-dioxo-17-oxa-3,13-diazapentacyclo(11.8.0.02,11.04,9.015,20)henicosa-1(21),2,4,6,8,10,15(20)-heptaen-19-yl) acetate, [(19S)-19-ethyl-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-19-yl] acetate, Camptothecin-20-acetate, CHEMBL430750, SCHEMBL5697379, 4-Ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl acetate, G86995, AE-641/10257064, Q27252932
Topological Polar Surface Area 85.8
Hydrogen Bond Donor Count 0.0
Heavy Atom Count 29.0
Isotope Atom Count 0.0
Molecular Complexity 846.0
Database Name cmaup_ingredients;pubchem
Defined Atom Stereocenter Count 1.0
Iupac Name [(19S)-19-ethyl-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-19-yl] acetate
Prediction Hob 1.0
Xlogp 1.6
Molecular Formula C22H18N2O5
Prediction Swissadme 1.0
Inchi Key ASVIEXKOXDCZDF-QFIPXVFZSA-N
Fcsp3 0.2727272727272727
Logs -4.801
Rotatable Bond Count 3.0
Logd 1.9
Compound Name Camptothecin acetate
Prediction Hob Swissadme 1.0
Exact Mass 390.122
Formal Charge 0.0
Monoisotopic Mass 390.122
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 390.4
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Esol -4.5182248620689665
Inchi InChI=1S/C22H18N2O5/c1-3-22(29-12(2)25)16-9-18-19-14(8-13-6-4-5-7-17(13)23-19)10-24(18)20(26)15(16)11-28-21(22)27/h4-9H,3,10-11H2,1-2H3/t22-/m0/s1
Smiles CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)OC(=O)C
Nring 5.0
Defined Bond Stereocenter Count 0.0