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Pinellic acid

PubChem CID: 9858729

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Compound Synonyms Pinellic acid, 97134-11-7, 9,12,13-TriHOME, 9S,12S,13S-trihydroxy-10E-octadecenoic acid, Dihydrofulgidic acid, (E,9S,12S,13S)-9,12,13-trihydroxyoctadec-10-enoic acid, 9(S),12(S),13(S)-Trihydroxy-10(E)-octadecenoic acid, CHEBI:34506, 9(S),12(S),13(S)-TriHOME, 9S,12S,13S-trihydroxy-10E-octadecenoate, (10E)-(9S,12S,13S)-9,12,13-Trihydroxyoctadec-10-enoic acid, 9(S),12(S),13(S)-Trihydroxy-10(E)-octadecenoate, (10E)-(9S,12S,13S)-9,12,13-Trihydroxyoctadec-10-enoate, (9S,10E,12S,13S)-9,12,13-trihydroxyoctadec-10-enoic acid, 9,12,13-Trihydroxyoctadec-10-enoic acid, SCHEMBL3989371, CHEMBL4436085, MDIUMSLCYIJBQC-MVFSOIOZSA-N, DTXSID001317644, LMFA02000014, AKOS040755725, DA-60617, PD131487, Q27116118, (9s,12s,13s)-e-9,12,13-trihydroxy-10-octadecaenoic acid
Topological Polar Surface Area 98.0
Hydrogen Bond Donor Count 4.0
Heavy Atom Count 23.0
Description 9,12,13-TriHOME is a trihydroxyoctadecenoic acid metabolite of linoleic acid, one of the major fatty acids found in lipids. Vascular tissue converts various polyunsaturated fatty acids to monohydroxy and trihydroxy metabolites derived from hydroperoxides which may be involved in regulating prostaglandin synthesis. The absolute amounts of 9,12,13-TriHOME varies considerably from one species to another. There are several possible mechanisms for the formation of esterified oxygenated polyunsaturated fatty acids: oxygenated and then incorporated into lipids, not well incorporated into either vascular endothelial or smooth muscle cells, or could accumulated in lipids either due to autoxidation in vivo or to the action of an enzyme similar to Iipoxygenase. (PMID: 3997883, 6414520) [HMDB]
Isotope Atom Count 0.0
Molecular Complexity 317.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;pubchem
Defined Atom Stereocenter Count 3.0
Iupac Name (E,9S,12S,13S)-9,12,13-trihydroxyoctadec-10-enoic acid
Prediction Hob 0.0
Class Fatty Acyls
Xlogp 3.1
Superclass Lipids and lipid-like molecules
Subclass Fatty acids and conjugates
Molecular Formula C18H34O5
Prediction Swissadme 0.0
Inchi Key MDIUMSLCYIJBQC-MVFSOIOZSA-N
Fcsp3 0.8333333333333334
Logs -3.589
Rotatable Bond Count 15.0
State Solid
Logd 2.118
Synonyms (10E)-(9S,12S,13S)-9,12,13-Trihydroxyoctadec-10-enoate, (10E)-(9S,12S,13S)-9,12,13-Trihydroxyoctadec-10-enoic acid, 9(S),12(S),13(S)-Trihydroxy-10(E)-octadecenoate, 9(S),12(S),13(S)-Trihydroxy-10(E)-octadecenoic acid, 9S,12S,13S-trihydroxy-10E-octadecenoate, 9S,12S,13S-trihydroxy-10E-octadecenoic acid, 9(S),12(S),13(S)-Trihydroxy-10(e)-octadecenoic acid, 9S,12S,13S-Trihydroxy-10E-octadecenoic acid, 9(S),12(S),13(S)-Trihydroxy-10(e)-octadecenoate, 9S,12S,13S-Trihydroxy-10E-octadecenoate, Pinellic acid
Substituent Name Long-chain fatty acid, Hydroxy fatty acid, Unsaturated fatty acid, Secondary alcohol, Polyol, 1,2-diol, Monocarboxylic acid or derivatives, Carboxylic acid, Carboxylic acid derivative, Hydrocarbon derivative, Organooxygen compound, Carbonyl group, Alcohol, Aliphatic acyclic compound
Compound Name Pinellic acid
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 330.241
Formal Charge 0.0
Monoisotopic Mass 330.241
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 330.5
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 1.0
Molecular Framework Aliphatic acyclic compounds
Esol -2.8833829999999994
Inchi InChI=1S/C18H34O5/c1-2-3-7-11-16(20)17(21)14-13-15(19)10-8-5-4-6-9-12-18(22)23/h13-17,19-21H,2-12H2,1H3,(H,22,23)/b14-13+/t15-,16-,17-/m0/s1
Smiles CCCCC[C@@H]([C@H](/C=C/[C@H](CCCCCCCC(=O)O)O)O)O
Nring 0.0
Defined Bond Stereocenter Count 1.0
Taxonomy Direct Parent Long-chain fatty acids

  • 1. Outgoing r'ship FOUND_IN to/from Chaenomeles Sinensis (Plant) Rel Props:Source_db:cmaup_ingredients
  • 2. Outgoing r'ship FOUND_IN to/from Chaenomeles Speciosa (Plant) Rel Props:Source_db:cmaup_ingredients
  • 3. Outgoing r'ship FOUND_IN to/from Panax Quinquefolius (Plant) Rel Props:Source_db:cmaup_ingredients
  • 4. Outgoing r'ship FOUND_IN to/from Perilla Frutescens (Plant) Rel Props:Source_db:cmaup_ingredients
  • 5. Outgoing r'ship FOUND_IN to/from Pinellia Ternata (Plant) Rel Props:Source_db:cmaup_ingredients